Overview
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The results showed that both strains significantly reduced the colonization and inflammatory responses in the stomach, evidenced by lower markers for inflammation and improved immune cell infiltration.
Overall, NCFM and Lp-115 appear to be promising options for helping to manage gastritis-related symptoms.
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Medical Researches
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This combination also helped lessen negative side effects from treatment. Thus, incorporating Lactobacillus acidophilus and other probiotics alongside traditional medications could be a game-changer in combatting H. pylori-related conditions.
In our study, mice that received the recombinant L. acidophilus showed significantly less H. pylori colonization compared to those who didn’t. This vaccine also stimulated both mucosal and systemic immune responses, indicated by increased antibody levels.
Overall, the results suggest that this approach could be a promising and cost-effective strategy to protect against H. pylori infections.
However, we also found concerning resistance rates to antibiotics like clarithromycin and metronidazole. This highlights an urgent need to adjust treatment strategies due to rising antibiotic resistance, while also showcasing the beneficial role probiotics may play in enhancing treatment outcomes.
The results showed that both strains significantly reduced the colonization and inflammatory responses in the stomach, evidenced by lower markers for inflammation and improved immune cell infiltration.
Overall, NCFM and Lp-115 appear to be promising options for helping to manage gastritis-related symptoms.
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Frequently Asked Questions
Gastritis is an inflammation of the stomach lining, which can lead to a range of symptoms including abdominal pain, nausea, vomiting, and indigestion. This condition can be acute, arising suddenly and lasting for a short period, or chronic, developing gradually and persisting over time. Various factors can contribute to gastritis, such as excessive alcohol consumption, prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs), bacterial infections (most notably Helicobacter pylori), and autoimmune disorders.
Treatment for gastritis often focuses on addressing the underlying cause and might include medications to reduce stomach acid, antibiotics for infections, and lifestyle modifications like avoiding irritating foods and beverages. While many people recover from gastritis with adequate care, it's important to consult a healthcare professional for a proper diagnosis and treatment plan. If left untreated, gastritis can lead to more serious complications, such as stomach ulcers or even an increased risk for gastric cancer.
Acidophilus, scientifically known as Lactobacillus acidophilus, is a type of beneficial bacteria that is commonly found in the human gut, as well as in fermented foods like yogurt and dietary supplements. This probiotic strain plays a crucial role in maintaining gut health by aiding digestion, enhancing nutrient absorption, and supporting the immune system. It is particularly known for its ability to break down lactose, making it easier for lactose-intolerant individuals to digest dairy products.
In addition to its digestive benefits, acidophilus has been studied for its potential to prevent or alleviate certain gastrointestinal issues, such as diarrhea and irritable bowel syndrome (IBS). Some research also suggests that it may support vaginal health by helping to maintain a balanced microbiome in women. When selecting a probiotic supplement that contains acidophilus, it is essential to look for products that contain live and active cultures, ensuring that you receive the full benefits of this beneficial bacteria. Always consult with a healthcare professional before beginning any new supplement regimen.
Acidophilus, a type of beneficial bacteria (probiotic) often found in yogurt and dietary supplements, may aid in digestive health, including conditions like gastritis. While research specifically linking Acidophilus to improved symptoms of gastritis is limited, probiotics in general have shown promise in supporting gut health and potentially reducing inflammation in the gastrointestinal tract. Gastritis, characterized by inflammation of the stomach lining, can be aggravated by factors such as stress, certain medications, and an imbalance of gut bacteria. By introducing beneficial bacteria and restoring this balance, Acidophilus may help alleviate some gastrointestinal symptoms.
However, it's important to note that the effectiveness of Acidophilus can vary from person to person, and it should not be considered a standalone treatment for gastritis. Consulting with a healthcare provider is crucial to develop a comprehensive treatment plan that may include dietary changes, medications, or specific probiotics. If you're dealing with gastritis symptoms, be sure to discuss the most appropriate options for you with your doctor before adding any new supplement to your regimen.
Based on user reviews, individuals taking this supplement for gastritis report varying times to notice improvements in their symptoms. Some users have experienced significant relief after just a few days of use, highlighting a rapid response in digestive health and a reduction in gastritis symptoms (Read Review). Others have noted that they felt positive changes after their very first capsule, suggesting that immediate effects are possible for some (Read Review).
However, for a sustained treatment plan, a longer-term commitment may be required, as one user recommends a six-month course for optimal results (Read Review). Overall, while some may experience quick relief, users indicate that persistence in taking the supplement will enhance its benefits, especially in conjunction with dietary considerations and other treatments.
Recent scientific studies provide promising evidence for the role of certain probiotic strains, specifically Lactobacillus, in managing gastritis, particularly when associated with Helicobacter pylori infection. One study indicated that Lactobacillus strains NCFM and Lp-115 significantly reduced inflammation by limiting the adhesion of H. pylori to gastric cells [1]. Similarly, the probiotic drink BIFICO, containing Lactobacillus acidophilus, showed an ability to soothe inflammation linked to H. pylori-related gastritis [2]. Furthermore, using Lactobacillus acidophilus in conjunction with conventional H. pylori treatments has been reported to enhance treatment efficacy, with one study noting a 100% eradication rate when combined with bismuth [3].
In addition to these findings, there's substantial evidence suggesting that probiotics can effectively reduce markers of inflammation and H. pylori colonization, which are critical in the management of gastritis [7]. Noteworthy, certain studies highlight that while probiotics can be beneficial, they may not completely replace traditional treatment protocols, underscoring the importance of a comprehensive approach to managing gastritis [13]. Overall, the scientific backing for using probiotics, particularly Lactobacillus strains, suggests a valid supplementary strategy for alleviating symptoms and complications associated with gastritis.
Users have reported a range of improvements in their gastritis symptoms and overall digestive health after taking this supplement. Many individuals noted feeling instant relief, with some experiencing noticeable changes after just the first dose; one user shared they felt a change right after the first pill (Read Review), while another remarked on feeling lightness in their digestive tract from the very first capsule (Read Review). Others highlighted significant long-term benefits, such as improved bowel regularity and the alleviation of constipation and bloating after consistent use over several days (Read Review).
Furthermore, users emphasized the supplement's positive impact on their overall digestion, citing decreases in symptoms like flatulence and indigestion, which have made it an essential part of their daily routine (Read Review). This indicates that while individual experiences may vary, many users found substantial relief from gastritis and enhancements to their digestive wellness, suggesting that a regular intake of the supplement can foster beneficial results.
Users have reported positive experiences when combining this supplement with other digestive aids to manage gastritis. One reviewer noted that they take the supplement alongside a complex of mushrooms and lecithin, experiencing significant relief from symptoms such as bloating and flatulence, which they claimed disappeared as a result of this combination (Read Review). Another user, who faced severe gut issues, mentioned that this supplement works effectively on its own but can also complement the use of antibiotics, enhancing overall digestion (Read Review).
However, caution is advised for those with gastritis due to high stomach acidity, as some probiotics may not be suitable in such cases. One user highlighted that while certain strains, like Acidophilus, are beneficial for gastritis and digestion, they might not be suitable for everyone, particularly those sensitive to acidity (Read Review). Overall, the feedback emphasizes that combining this supplement with other digestive health products can amplify its effects for those managing gastritis, provided the individual considers their specific health needs.
Users report various dosing strategies for Acidophilus when using it to manage gastritis. Many recommend taking one capsule daily, often during or after a meal, which users found effective in alleviating symptoms. One reviewer noted, "I take one capsule during or after a meal," and mentioned that their treatment lasted six months with no side effects ((Read Review)). Another user affirmed a similar dosing regimen, stating, "I take one a day," to effectively address their digestive issues, tied to their gastritis ((Read Review)).
The general consensus among users is that starting with one capsule can lead to noticeable improvements in digestion and gastritis symptoms. Some individuals have opted for a nightly dose, reporting that taking "one tablet at night" helped them feel "great during the day" ((Read Review)). Despite minor variations in individual preferences, it seems that a daily dose of one capsule is a commonly reported approach for many users seeking relief from gastritis symptoms.
The results showed that both strains significantly reduced the colonization and inflammatory responses in the stomach, evidenced by lower markers for inflammation and improved immune cell infiltration.
Overall, NCFM and Lp-115 appear to be promising options for helping to manage gastritis-related symptoms.
This combination also helped lessen negative side effects from treatment. Thus, incorporating Lactobacillus acidophilus and other probiotics alongside traditional medications could be a game-changer in combatting H. pylori-related conditions.
In this study, various groups were treated with either antibiotics or Lactobacillus strains, and their gastritis was evaluated through detailed analysis. Both strains showed effectiveness in reducing H. pylori density and inflammation, indicating potential benefits for treating gastritis.
However, it's important to note that L. fermenti exhibited stronger anti-H. pylori activity compared to L. acidophilus.
References
- Shen S, Ren F, Qin H, Bukhari I, Yang J, et al. NCFM and Lp-115 inhibit colonization and gastric inflammation in a murine model. Front Cell Infect Microbiol. 2023;13:1196084. doi:10.3389/fcimb.2023.1196084
- Yu HJ, Liu W, Chang Z, Shen H, He LJ, et al. Probiotic BIFICO cocktail ameliorates Helicobacter pylori induced gastritis. World J Gastroenterol. 2015;21:6561. doi:10.3748/wjg.v21.i21.6561
- Srinarong C, Siramolpiwat S, Wongcha-um A, Mahachai V, Vilaichone RK. Improved eradication rate of standard triple therapy by adding bismuth and probiotic supplement for Helicobacter pylori treatment in Thailand. Asian Pac J Cancer Prev. 2014;15:9909.
- Hongying F, Xianbo W, Fang Y, Yang B, Beiguo L. Oral immunization with recombinant Lactobacillus acidophilus expressing the adhesin Hp0410 of Helicobacter pylori induces mucosal and systemic immune responses. Clin Vaccine Immunol. 2014;21:126. doi:10.1128/CVI.00434-13
- Du YQ, Su T, Fan JG, Lu YX, Zheng P, et al. Adjuvant probiotics improve the eradication effect of triple therapy for Helicobacter pylori infection. World J Gastroenterol. 2012;18:6302. doi:10.3748/wjg.v18.i43.6302
- Hsieh PS, Tsai YC, Chen YC, Teh SF, Ou CM, et al. Eradication of Helicobacter pylori infection by the probiotic strains Lactobacillus johnsonii MH-68 and L. salivarius ssp. salicinius AP-32. Helicobacter. 2012;17:466. doi:10.1111/j.1523-5378.2012.00992.x
- Cui Y, Wang CL, Liu XW, Wang XH, Chen LL, et al. Two stomach-originated Lactobacillus strains improve Helicobacter pylori infected murine gastritis. World J Gastroenterol. 2010;16:445.
- Zwolińska-Wcisło M, Brzozowski T, Mach T, Budak A, Trojanowska D, et al. Are probiotics effective in the treatment of fungal colonization of the gastrointestinal tract? Experimental and clinical studies. J Physiol Pharmacol. 2006;57 Suppl 9:35.
- Ziemniak W. Efficacy of Helicobacter pylori eradication taking into account its resistance to antibiotics. J Physiol Pharmacol. 2006;57 Suppl 3:123.
- Johnson-Henry KC, Mitchell DJ, Avitzur Y, Galindo-Mata E, Jones NL, et al. Probiotics reduce bacterial colonization and gastric inflammation in H. pylori-infected mice. Dig Dis Sci. 2004;49:1095.
- Felley CP, Corthésy-Theulaz I, Rivero JL, Sipponen P, Kaufmann M, et al. Favourable effect of an acidified milk (LC-1) on Helicobacter pylori gastritis in man. Eur J Gastroenterol Hepatol. 2001;13:25.
- Michetti P, Dorta G, Wiesel PH, Brassart D, Verdu E, et al. Effect of whey-based culture supernatant of Lactobacillus acidophilus (johnsonii) La1 on Helicobacter pylori infection in humans. Digestion. 1999;60:203.
- Mrda Z, Zivanović M, Rasić J, Gajin S, Somer L, et al. [Therapy of Helicobacter pylori infection using Lactobacillus acidophilus]. Med Pregl. 1998;51:343.
- Bhatia SJ, Kochar N, Abraham P, Nair NG, Mehta AP. Lactobacillus acidophilus inhibits growth of Campylobacter pylori in vitro. J Clin Microbiol. 1989;27:2328.
