Last update
5/22/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8
USERS' SCORE
Good
Based on 8 Reviews
8
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Proprietary Blend Containing 1 billion live cultures† Lactobacillus acidophilus Lactobacillus salivarius Bifidobacterium bifidum Streptococcus thermophilus
175 mg
**
Top Medical Research Studies
7
We explored the impact of Lactobacillus acidophilus and other probiotics on children suffering from acute gastroenteritis. Our systematic review included randomized controlled trials comparing probiotics to placebos, focusing on strains available in Japan.
Although we found that probiotics like Lactobacillus acidophilus might shorten diarrhea duration by roughly one day, the evidence is not very strong.
Overall, while there were some positive signs in our findings, we recommend more research to confirm these effects and improve treatment strategies.
Although we found that probiotics like Lactobacillus acidophilus might shorten diarrhea duration by roughly one day, the evidence is not very strong.
Overall, while there were some positive signs in our findings, we recommend more research to confirm these effects and improve treatment strategies.
Read More
8
We explored the impact of Lactobacillus acidophilus (LA) on inflammation and oxidative stress caused by Salmonella Typhimurium in mice. After treating the mice with LA for 14 days, we observed significant improvements in gut health. LA reduced harmful serum compounds and boosted antioxidant enzyme levels, supporting better recovery.
The study also highlighted how LA regulates gut bacteria, suggesting it could be useful for disease resistance. While the research focused on animal models, it offers promising insights for future solutions in gut health and disease prevention.
The study also highlighted how LA regulates gut bacteria, suggesting it could be useful for disease resistance. While the research focused on animal models, it offers promising insights for future solutions in gut health and disease prevention.
Read More
7
We examined how the introduction of routine supplementation with Bifidobacterium bifidum and Lactobacillus acidophilus affects outcomes in very preterm infants. Through a retrospective study comparing two six-year periods, we looked at infants less than 32 weeks gestation.
Our findings revealed a significant reduction in severe necrotising enterocolitis (NEC) and death after starting probiotic administration, showing improved outcomes for these vulnerable infants. This suggests that probiotics may play a crucial role in neonatal care.
Our findings revealed a significant reduction in severe necrotising enterocolitis (NEC) and death after starting probiotic administration, showing improved outcomes for these vulnerable infants. This suggests that probiotics may play a crucial role in neonatal care.
Read More
Most Useful Reviews
9
Pain relief achieved
8 people found this helpful
I was suffering from significant stomach pain, and the gastroenterologist advised that I should enhance my intestinal flora. He recommended adding a probiotic to my diet, which has been tremendously helpful. My pain and swelling have reduced considerably, and I take it before bed.
Read More
7.5
Significant improvements noted
6 people found this helpful
Upon the gastroenterologist's recommendation, I began using this probiotic and noticed a marked improvement in my stomach pains and bowel movements. Besides Acidophilus, it contains other strains that assist in intestinal regulation. Highly approved!
Read More
7.5
Marked intestinal improvement
2 people found this helpful
I have been using this probiotic for a month, and I’m experiencing substantial improvements. Being lactose intolerant, this product has significantly enhanced my gut health. Previously tried others without improvement. My gastro recommended it, stating it notably benefits women's health regarding candidiasis.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8
- All Researches
9
Probiotics improve poultry health
We combined findings from three separate trials to evaluate the effects of a dual-strain probiotic consisting of Lactobacillus acidophilus and Bifidobacterium animalis on broilers facing mild necrotic enteritis.
In these studies, birds receiving the probiotic showed improved growth and feed intake, alongside a reduction in mortality and intestinal lesions compared to untreated controls.
This suggests that probiotics can effectively counter the adverse impacts of necrotic enteritis in poultry, enhancing overall gut health and growth performance.
In these studies, birds receiving the probiotic showed improved growth and feed intake, alongside a reduction in mortality and intestinal lesions compared to untreated controls.
This suggests that probiotics can effectively counter the adverse impacts of necrotic enteritis in poultry, enhancing overall gut health and growth performance.
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9
We explored how two strains of Lactobacillus, NCFM and Lp-115, can help tackle the pesky H. pylori bacteria that often lead to gastric inflammation.
In a controlled study using mice, we treated groups with these probiotics for six weeks. Results showed that both strains significantly reduced H. pylori adhesion and the inflammation response in stomach tissues.
This suggests that Lactobacillus could be a promising ally in managing the negative effects of gastric infections.
In a controlled study using mice, we treated groups with these probiotics for six weeks. Results showed that both strains significantly reduced H. pylori adhesion and the inflammation response in stomach tissues.
This suggests that Lactobacillus could be a promising ally in managing the negative effects of gastric infections.
Read More
9
This study looked into how Lactobacillus acidophilus LA85 impacts ulcerative colitis in mice. We established a mouse model of this condition by using a chemical solution that triggers colitis symptoms.
The results were encouraging: mice treated with L. acidophilus LA85 showed significant improvements, such as less weight loss and reduced colon damage compared to untreated counterparts.
Additionally, this probiotic helped balance gut bacteria and improved inflammation markers, making it a promising option for addressing similar conditions in humans.
The results were encouraging: mice treated with L. acidophilus LA85 showed significant improvements, such as less weight loss and reduced colon damage compared to untreated counterparts.
Additionally, this probiotic helped balance gut bacteria and improved inflammation markers, making it a promising option for addressing similar conditions in humans.
Read More
8
We explored the impact of Lactobacillus acidophilus (LA) on inflammation and oxidative stress caused by Salmonella Typhimurium in mice. After treating the mice with LA for 14 days, we observed significant improvements in gut health. LA reduced harmful serum compounds and boosted antioxidant enzyme levels, supporting better recovery.
The study also highlighted how LA regulates gut bacteria, suggesting it could be useful for disease resistance. While the research focused on animal models, it offers promising insights for future solutions in gut health and disease prevention.
The study also highlighted how LA regulates gut bacteria, suggesting it could be useful for disease resistance. While the research focused on animal models, it offers promising insights for future solutions in gut health and disease prevention.
Read More
7
We explored the impact of Lactobacillus acidophilus and other probiotics on children suffering from acute gastroenteritis. Our systematic review included randomized controlled trials comparing probiotics to placebos, focusing on strains available in Japan.
Although we found that probiotics like Lactobacillus acidophilus might shorten diarrhea duration by roughly one day, the evidence is not very strong.
Overall, while there were some positive signs in our findings, we recommend more research to confirm these effects and improve treatment strategies.
Although we found that probiotics like Lactobacillus acidophilus might shorten diarrhea duration by roughly one day, the evidence is not very strong.
Overall, while there were some positive signs in our findings, we recommend more research to confirm these effects and improve treatment strategies.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Pain relief achieved
8 people found this helpful
I was suffering from significant stomach pain, and the gastroenterologist advised that I should enhance my intestinal flora. He recommended adding a probiotic to my diet, which has been tremendously helpful. My pain and swelling have reduced considerably, and I take it before bed.
Read More
7.5
Significant improvements noted
6 people found this helpful
Upon the gastroenterologist's recommendation, I began using this probiotic and noticed a marked improvement in my stomach pains and bowel movements. Besides Acidophilus, it contains other strains that assist in intestinal regulation. Highly approved!
Read More
7.5
Marked intestinal improvement
2 people found this helpful
I have been using this probiotic for a month, and I’m experiencing substantial improvements. Being lactose intolerant, this product has significantly enhanced my gut health. Previously tried others without improvement. My gastro recommended it, stating it notably benefits women's health regarding candidiasis.
Read More
7.5
Effective for gastroenteritis
Works for gastroenteritis and ulcers. I was initially sceptical, but this definitely works. I suffer from severe gastroenteritis, possibly an ulcer and IBS, and I noticed a difference after starting these. Just one capsule a day sufficed for me. However, when my stomach was healthy, I didn’t see much change, suggesting that if you don’t have serious digestive issues, the effects may not be as pronounced. I paused taking them for two years but returned, and they still worked! However, be cautious with frequent constipation; high doses of acidophilus can worsen it. It's more effective for diarrhoea. People often overlook this, leading to complaints. For constipation, one requires bifidum. This blend includes bifidum too but check the dosage of acidophilus to avoid complications. My only issue is that they contain gelatin and whey, which I overlooked when purchasing.
Read More
7.5
Helps gut condition
I bought this for a friend with acute gastroenteritis, and she claims this product helps her gut significantly.
Read More
Frequently Asked Questions
7.5
Helps gut condition
I bought this for a friend with acute gastroenteritis, and she claims this product helps her gut significantly.
6
Slight improvement noted
When you experience mild gastroenteritis, these can help slightly improve diarrhoea.
7.5
Effective for gastroenteritis
Works for gastroenteritis and ulcers. I was initially sceptical, but this definitely works. I suffer from severe gastroenteritis, possibly an ulcer and IBS, and I noticed a difference after starting these. Just one capsule a day sufficed for me. However, when my stomach was healthy, I didn’t see much change, suggesting that if you don’t have serious digestive issues, the effects may not be as pronounced. I paused taking them for two years but returned, and they still worked! However, be cautious with frequent constipation; high doses of acidophilus can worsen it. It's more effective for diarrhoea. People often overlook this, leading to complaints. For constipation, one requires bifidum. This blend includes bifidum too but check the dosage of acidophilus to avoid complications. My only issue is that they contain gelatin and whey, which I overlooked when purchasing.
5
Good condition maintained
With hypersensitivity gastroenteritis, I tried acidophilus and found it effective. It's not without impact, as my condition has remained stable; I've not caught a cold. Despite using various products, I feel this one has kept me in good condition without specific changes. The quantity is ample, making it a good deal, but I wonder if I should rotate it monthly. I'm curious if the bacteria remain effective even when refrigerated. I'd like to try it again.
7
We explored the impact of Lactobacillus acidophilus and other probiotics on children suffering from acute gastroenteritis. Our systematic review included randomized controlled trials comparing probiotics to placebos, focusing on strains available in Japan.
Although we found that probiotics like Lactobacillus acidophilus might shorten diarrhea duration by roughly one day, the evidence is not very strong.
Overall, while there were some positive signs in our findings, we recommend more research to confirm these effects and improve treatment strategies.
Although we found that probiotics like Lactobacillus acidophilus might shorten diarrhea duration by roughly one day, the evidence is not very strong.
Overall, while there were some positive signs in our findings, we recommend more research to confirm these effects and improve treatment strategies.
7
We reviewed multiple databases for studies on using Lactobacillus acidophilus to treat acute gastroenteritis in children. Our analysis incorporated 15 randomized controlled trials with 1,765 young patients.
While Lactobacillus acidophilus appeared to shorten diarrhea duration when used at a daily dose of 10 CFU or more, this finding wasn't statistically significant for single strains. It did show some effectiveness in reducing diarrhea frequency after a few days, primarily on day three.
However, the evidence overall remains moderate to low in quality, suggesting the need for further research.
While Lactobacillus acidophilus appeared to shorten diarrhea duration when used at a daily dose of 10 CFU or more, this finding wasn't statistically significant for single strains. It did show some effectiveness in reducing diarrhea frequency after a few days, primarily on day three.
However, the evidence overall remains moderate to low in quality, suggesting the need for further research.
8
We explored the impact of Lactobacillus acidophilus (LA) on inflammation and oxidative stress caused by Salmonella Typhimurium in mice. After treating the mice with LA for 14 days, we observed significant improvements in gut health. LA reduced harmful serum compounds and boosted antioxidant enzyme levels, supporting better recovery.
The study also highlighted how LA regulates gut bacteria, suggesting it could be useful for disease resistance. While the research focused on animal models, it offers promising insights for future solutions in gut health and disease prevention.
The study also highlighted how LA regulates gut bacteria, suggesting it could be useful for disease resistance. While the research focused on animal models, it offers promising insights for future solutions in gut health and disease prevention.
References
- Li H, Ma X, Shang Z, Liu X, Qiao J. alleviate Serovar Typhimurium-induced murine inflammatory/oxidative responses via the p62-Keap1-Nrf2 signaling pathway and cecal microbiota. Front Microbiol. 2024;15:1483705. 10.3389/fmicb.2024.1483705
- van der Klein SAS, Bernardeau M, Wang Q, Gibbs K. A cross-study analysis of the effect of a dual-strain probiotic applied via the waterline on the growth performance and gut health of broilers under a mild necrotic enteritis challenge. Poult Sci. 2025;104:104550. 10.1016/j.psj.2024.104550
- Higuchi T, Furuichi M, Maeda N, Tsugawa T, Ito K. Effects of probiotics in children with acute gastroenteritis: A systematic review and meta-analysis focusing on probiotics utilized in Japan. J Infect Chemother. 2024;30:337. 10.1016/j.jiac.2023.11.005
- Shen S, Ren F, Qin H, Bukhari I, Yang J, et al. NCFM and Lp-115 inhibit colonization and gastric inflammation in a murine model. Front Cell Infect Microbiol. 2023;13:1196084. 10.3389/fcimb.2023.1196084
- Han M, Liao W, Dong Y, Fei T, Gai Z. Sustained ameliorative effect of Lactobacillus acidophilus LA85 on dextran sulfate sodium-induced colitis in mice. J Food Sci. 2023;88:3893. 10.1111/1750-3841.16723
- Healy DB, Campbell-Green B, Livingstone V, Ryan CA, Ross RP, et al. Neonatal outcomes following introduction of routine probiotic supplementation to very preterm infants. Acta Paediatr. 2023;112:2093. 10.1111/apa.16923
- Cheng H, Ma Y, Liu X, Tian C, Zhong X, et al. A Systematic Review and Meta-Analysis: for Treating Acute Gastroenteritis in Children. Nutrients. 2022;14. 10.3390/nu14030682
