Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 33 Researches
7.4
USERS' SCORE
Moderately Good
Based on 208 Reviews
7.5
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Proprietary Blend Containing 1 billion live cultures† Lactobacillus acidophilus Lactobacillus salivarius Bifidobacterium bifidum Streptococcus thermophilus
175 mg
**
Top Medical Research Studies
9.5
In our clinical trial, we examined the effects of a probiotic combination of Lactobacillus acidophilus and L. plantarum on patients with diarrhea-predominant irritable bowel syndrome (IBS-D). We randomly assigned 100 participants to standard IBS treatment or the same treatment plus probiotics over 12 weeks.
Both groups experienced significant symptom relief, but those taking probiotics saw even greater improvements. By the end of the study, everyone in the probiotic group achieved either complete remission or mild symptoms, while some in the standard treatment group still reported moderate issues. These results suggest that adding probiotics could enhance IBS management strategies.
Both groups experienced significant symptom relief, but those taking probiotics saw even greater improvements. By the end of the study, everyone in the probiotic group achieved either complete remission or mild symptoms, while some in the standard treatment group still reported moderate issues. These results suggest that adding probiotics could enhance IBS management strategies.
Read More
9.5
Bifidobacterium bifidum improves IBS symptoms
We assessed how Bifidobacterium bifidum MIMBb75 impacts symptoms of irritable bowel syndrome (IBS) in a controlled study of 122 participants.
Over four weeks, those taking MIMBb75 reported significantly reduced IBS symptoms compared to the placebo group.
With many experiencing better pain relief and improved quality of life, these findings suggest that MIMBb75 could be a valuable treatment option for IBS, showing durability with minimal side effects.
Over four weeks, those taking MIMBb75 reported significantly reduced IBS symptoms compared to the placebo group.
With many experiencing better pain relief and improved quality of life, these findings suggest that MIMBb75 could be a valuable treatment option for IBS, showing durability with minimal side effects.
Read More
9
Heat-inactivated Bifidobacterium alleviates IBS
We examined how heat-inactivated Bifidobacterium bifidum MIMBb75 can help those suffering from irritable bowel syndrome (IBS). In a well-structured double-blind study involving 443 patients, we found that 34% of those taking the probiotic reported significant relief from abdominal pain and IBS symptoms, compared to just 19% in the placebo group.
Importantly, the probiotic was well-tolerated, with no serious side effects. This research suggests that even non-viable probiotics can effectively support IBS treatment, thanks to their unique beneficial properties.
Importantly, the probiotic was well-tolerated, with no serious side effects. This research suggests that even non-viable probiotics can effectively support IBS treatment, thanks to their unique beneficial properties.
Read More
Most Useful Reviews
9
Regular bowel movements
109 people found this helpful
This probiotic has greatly helped my irritable bowel syndrome since childhood. I used to have stool problems and bloating, but after taking one tablet at night, I now have regular bowel movements twice a day. The gassiness has decreased significantly too. I will continue to order it and plan to share it with my mother as well.
Read More
9
Family-friendly
38 people found this helpful
As we age, digestive issues can arise, and I began taking these probiotics after my doctor's recommendation for irritable bowel syndrome. Initially, I had a bowel movement every day. Now, my whole family is using it, appreciating both the affordable price and the positive effects on our intestinal health. I strongly recommend this product.
Read More
9
Effective probiotic
31 people found this helpful
This probiotic works effectively for my irritable bowel syndrome. I take one capsule every morning on an empty stomach, and my stools have normalised. My digestive system now functions smoothly. A recent experiment showed active bacteria in my milk when I added this probiotic, further proving its efficacy.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 33 Researches
7.4
- All Researches
9.5
In our clinical trial, we examined the effects of a probiotic combination of Lactobacillus acidophilus and L. plantarum on patients with diarrhea-predominant irritable bowel syndrome (IBS-D). We randomly assigned 100 participants to standard IBS treatment or the same treatment plus probiotics over 12 weeks.
Both groups experienced significant symptom relief, but those taking probiotics saw even greater improvements. By the end of the study, everyone in the probiotic group achieved either complete remission or mild symptoms, while some in the standard treatment group still reported moderate issues. These results suggest that adding probiotics could enhance IBS management strategies.
Both groups experienced significant symptom relief, but those taking probiotics saw even greater improvements. By the end of the study, everyone in the probiotic group achieved either complete remission or mild symptoms, while some in the standard treatment group still reported moderate issues. These results suggest that adding probiotics could enhance IBS management strategies.
Read More
9.5
This randomized, single-blinded trial evaluated the impact of probiotics, specifically Lactobacillus acidophilus and plantarum, on patients with diarrhea-predominant irritable bowel syndrome (IBS-D).
We found that when added to standard IBS treatment, these probiotics significantly improved symptoms over a 12-week period.
Group B, the probiotic group, experienced better results, including fewer days with pain and greater satisfaction with bowel habits. While both groups saw reductions in IBS severity, the probiotics led to complete remission in many patients, which is promising for future treatment guidelines.
We found that when added to standard IBS treatment, these probiotics significantly improved symptoms over a 12-week period.
Group B, the probiotic group, experienced better results, including fewer days with pain and greater satisfaction with bowel habits. While both groups saw reductions in IBS severity, the probiotics led to complete remission in many patients, which is promising for future treatment guidelines.
Read More
9.5
Bifidobacterium bifidum improves IBS symptoms
We assessed how Bifidobacterium bifidum MIMBb75 impacts symptoms of irritable bowel syndrome (IBS) in a controlled study of 122 participants.
Over four weeks, those taking MIMBb75 reported significantly reduced IBS symptoms compared to the placebo group.
With many experiencing better pain relief and improved quality of life, these findings suggest that MIMBb75 could be a valuable treatment option for IBS, showing durability with minimal side effects.
Over four weeks, those taking MIMBb75 reported significantly reduced IBS symptoms compared to the placebo group.
With many experiencing better pain relief and improved quality of life, these findings suggest that MIMBb75 could be a valuable treatment option for IBS, showing durability with minimal side effects.
Read More
9
Probiotic milk improves IBS symptoms
We examined the effects of a daily cultured milk drink containing Lactobacillus acidophilus on individuals with constipation-predominant irritable bowel syndrome (IBS-C). Over 30 days, participants reported significant relief in constipation symptoms alongside improved intestinal transit time and decreased fecal pH.
Notably, the pro-inflammatory cytokines levels also dropped significantly, indicating a positive immune response. These results suggest that incorporating probiotic-rich cultured milk drinks might serve as a helpful addition to treat this condition effectively.
Notably, the pro-inflammatory cytokines levels also dropped significantly, indicating a positive immune response. These results suggest that incorporating probiotic-rich cultured milk drinks might serve as a helpful addition to treat this condition effectively.
Read More
9
We investigated the effects of two probiotic strains, DDS-1 and UABla-12, on abdominal pain and symptoms in people with irritable bowel syndrome (IBS). In a well-structured study involving 330 participants, those receiving probiotics experienced significant improvements in pain severity compared to a placebo group.
The DDS-1 strain showed a 52.3% response rate, while UABla-12 had a 28.2% response. Both probiotics also improved overall IBS symptoms, bowel consistency, and quality of life measures.
These findings suggest that probiotics could be a beneficial option for managing IBS symptoms.
The DDS-1 strain showed a 52.3% response rate, while UABla-12 had a 28.2% response. Both probiotics also improved overall IBS symptoms, bowel consistency, and quality of life measures.
These findings suggest that probiotics could be a beneficial option for managing IBS symptoms.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 208 Reviews
7.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Regular bowel movements
109 people found this helpful
This probiotic has greatly helped my irritable bowel syndrome since childhood. I used to have stool problems and bloating, but after taking one tablet at night, I now have regular bowel movements twice a day. The gassiness has decreased significantly too. I will continue to order it and plan to share it with my mother as well.
Read More
9
Family-friendly
38 people found this helpful
As we age, digestive issues can arise, and I began taking these probiotics after my doctor's recommendation for irritable bowel syndrome. Initially, I had a bowel movement every day. Now, my whole family is using it, appreciating both the affordable price and the positive effects on our intestinal health. I strongly recommend this product.
Read More
9
Effective probiotic
31 people found this helpful
This probiotic works effectively for my irritable bowel syndrome. I take one capsule every morning on an empty stomach, and my stools have normalised. My digestive system now functions smoothly. A recent experiment showed active bacteria in my milk when I added this probiotic, further proving its efficacy.
Read More
7.5
Affordable alternative
29 people found this helpful
Despite having irritable bowel syndrome, I found this cheap yet highly rated probiotic effective for my digestive issues. After taking one tablet before bed, my stool has been normalised without discomfort. This affordable option works better for me than pricier alternatives, and I plan to continue using it.
Read More
9
Cured candida
26 people found this helpful
A product I repeatedly use! I heard acidophilus is effective against candida. I had esophageal candida for two years, but after trying this, I noticed it had cleared up, and I haven’t experienced symptoms since. My bowel movements have also improved, leading my whole family to take it due to its bifidobacteria content.
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Frequently Asked Questions
9
Significant improvement
11 people found this helpful
I purchased this for my father, who suffers from irritable bowel syndrome. After just five days, he's experienced marked improvement. The 150-pack offers great value compared to similar products. I even make yogurt with it, which turned out excellent.
9
Reduced intestinal pain
4 people found this helpful
Having suffered from irritable bowel syndrome for years, I sought probiotics with acidophilus bacillus that endure digestive juices. After a week of taking capsules with food and making yoghurt, the pain in my intestines has vanished, bringing immense relief and happiness.
9
Daily digestion support
5 people found this helpful
I've taken this supplement for three months and started with one capsule each evening, sometimes two after larger meals. It aids digestion, absorbed easily, and eliminated issues such as constipation and gas. Now, I have smooth bowel movements daily without discomfort.
9
Regular bowel movements
109 people found this helpful
This probiotic has greatly helped my irritable bowel syndrome since childhood. I used to have stool problems and bloating, but after taking one tablet at night, I now have regular bowel movements twice a day. The gassiness has decreased significantly too. I will continue to order it and plan to share it with my mother as well.
9
Effective probiotic
31 people found this helpful
This probiotic works effectively for my irritable bowel syndrome. I take one capsule every morning on an empty stomach, and my stools have normalised. My digestive system now functions smoothly. A recent experiment showed active bacteria in my milk when I added this probiotic, further proving its efficacy.
9
Family-friendly
38 people found this helpful
As we age, digestive issues can arise, and I began taking these probiotics after my doctor's recommendation for irritable bowel syndrome. Initially, I had a bowel movement every day. Now, my whole family is using it, appreciating both the affordable price and the positive effects on our intestinal health. I strongly recommend this product.
2
Increased gas issue
5 people found this helpful
There was no effect from the 2,000 lbf of lactic acid bacteria. My gas problems worsened, which is distressing with irritable bowel syndrome. I now struggle to sleep due to stomach discomfort.
9
Bowel movement improvement
14 people found this helpful
I struggled with bowel movements for a week, facing bloating and hard stools, but after taking apple pectin with probiotics, my stools softened. I now drink warm water in the morning, leading to quick bowel movements. Probiotics have not only improved my digestion over four months but also eliminated body odour, while my skin has become less oily.
9
Irritable bowel relief
14 people found this helpful
I combine various probiotics for my irritable bowel syndrome. Since I started taking these, I no longer experience diarrhoea or constipation. My husband also benefited when he tried a tablet for his stomach issues. We continue using it for better health.
9
Noticed digestive relief
19 people found this helpful
I have chronic pancreatitis, hyperacidity, and irritable bowel syndrome. After trying numerous ineffective alternatives, this product resolved my digestive issues with as little as one to two capsules daily. It’s been a life-changer, and I highly recommend it.
9
Improved bowel movement
5 people found this helpful
I have taken probiotics for a month now, and I can say they have significantly improved my bowel movements. I previously suffered from diarrhoea daily, but it is now much easier for me to go to the toilet. Initially, I experienced some bloating when taking it during the day, so I switched to taking it at night. Please note this is not medical advice, just my experience.
9.5
In our clinical trial, we examined the effects of a probiotic combination of Lactobacillus acidophilus and L. plantarum on patients with diarrhea-predominant irritable bowel syndrome (IBS-D). We randomly assigned 100 participants to standard IBS treatment or the same treatment plus probiotics over 12 weeks.
Both groups experienced significant symptom relief, but those taking probiotics saw even greater improvements. By the end of the study, everyone in the probiotic group achieved either complete remission or mild symptoms, while some in the standard treatment group still reported moderate issues. These results suggest that adding probiotics could enhance IBS management strategies.
Both groups experienced significant symptom relief, but those taking probiotics saw even greater improvements. By the end of the study, everyone in the probiotic group achieved either complete remission or mild symptoms, while some in the standard treatment group still reported moderate issues. These results suggest that adding probiotics could enhance IBS management strategies.
9
We investigated the effects of two probiotic strains, DDS-1 and UABla-12, on abdominal pain and symptoms in people with irritable bowel syndrome (IBS). In a well-structured study involving 330 participants, those receiving probiotics experienced significant improvements in pain severity compared to a placebo group.
The DDS-1 strain showed a 52.3% response rate, while UABla-12 had a 28.2% response. Both probiotics also improved overall IBS symptoms, bowel consistency, and quality of life measures.
These findings suggest that probiotics could be a beneficial option for managing IBS symptoms.
The DDS-1 strain showed a 52.3% response rate, while UABla-12 had a 28.2% response. Both probiotics also improved overall IBS symptoms, bowel consistency, and quality of life measures.
These findings suggest that probiotics could be a beneficial option for managing IBS symptoms.
We examined the effects of a specific synbiotic preparation on patients suffering from diarrhea-predominant irritable bowel syndrome (IBS-D).
In a randomized, double-blind trial with eighty participants, those receiving synbiotics showed significant improvements in symptom severity after eight weeks, particularly in areas related to flatulence and bowel habits.
Patients reported feeling less discomfort overall and noticed an enhancement in stool consistency.
Importantly, no increased adverse events were observed, indicating the treatment was safe and well-tolerated.
In a randomized, double-blind trial with eighty participants, those receiving synbiotics showed significant improvements in symptom severity after eight weeks, particularly in areas related to flatulence and bowel habits.
Patients reported feeling less discomfort overall and noticed an enhancement in stool consistency.
Importantly, no increased adverse events were observed, indicating the treatment was safe and well-tolerated.
References
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- Sarkawi M, Raja Ali RA, Abdul Wahab N, Abdul Rathi ND, Mokhtar NM. A randomized, double-blinded, placebo-controlled clinical trial on Lactobacillus-containing cultured milk drink as adjuvant therapy for depression in irritable bowel syndrome. Sci Rep. 2024;14:9478. 10.1038/s41598-024-60029-2
- Shanshal SA, Alsaaty MH, Al-Qazaz H, Al-Zidan RN. Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial. Ceska Slov Farm. 2024;72:233.
- Chang YH, Choi YJ, Shin CM, Moon JS, Kim TY, et al. Efficacy of Quadruple-coated Probiotics in Patients With Irritable Bowel Syndrome: A Randomized, Double-blind, Placebo-controlled, Parallel-group Study. J Neurogastroenterol Motil. 2024;30:73. 10.5056/jnm23036
- Drozdov VN, Shikh EV, Astapovskii AA, Khalaidzheva KN, Solovieva SA, et al. [Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea and antibiotic-associated diarrhea]. Vopr Pitan. 2023;92:92. 10.33029/0042-8833-2023-92-4-92-103
- Cocetta V, Giacomini I, Tinazzi M, Berretta M, Quagliariello V, et al. Maintenance of intestinal epithelial barrier integrity by a combination of probiotics, herbal extract, and vitamins. Minerva Pediatr (Torino). 2023. 10.23736/S2724-5276.23.07128-8
- Mokhtar NM, Jaafar NM, Alfian E, Mohd Rathi ND, Abdul Rani R, et al. Clinical assessment and cytokines level in constipation-predominant irritable bowel syndrome participants treated with Lactobacillus-containing cultured milk drink. Acta Gastroenterol Belg. 2021;84:585. 10.51821/84.4.009
- Skrzydło-Radomańska B, Prozorow-Król B, Cichoż-Lach H, Majsiak E, Bierła JB, et al. The Effectiveness of Synbiotic Preparation Containing and Probiotic Strains and Short Chain Fructooligosaccharides in Patients with Diarrhea Predominant Irritable Bowel Syndrome-A Randomized Double-Blind, Placebo-Controlled Study. Nutrients. 2020;12. 10.3390/nu12071999
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- Martoni CJ, Srivastava S, Leyer GJ. DDS-1 and UABla-12 Improve Abdominal Pain Severity and Symptomology in Irritable Bowel Syndrome: Randomized Controlled Trial. Nutrients. 2020;12. 10.3390/nu12020363
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- Preston K, Krumian R, Hattner J, de Montigny D, Stewart M, et al. Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R and Lactobacillus rhamnosus CLR2 improve quality-of-life and IBS symptoms: a double-blind, randomised, placebo-controlled study. Benef Microbes. 2018;9:697. 10.3920/BM2017.0105
- Leventogiannis K, Gkolfakis P, Spithakis G, Tsatali A, Pistiki A, et al. Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritable Bowel Syndrome: Association with Intestinal Bacterial Overgrowth. Probiotics Antimicrob Proteins. 2019;11:627. 10.1007/s12602-018-9401-3
- Sadrin S, Sennoune SR, Gout B, Marque S, Moreau J, et al. Lactobacillus acidophilus versus placebo in the symptomatic treatment of irritable bowel syndrome: the LAPIBSS randomized trial. Cell Mol Biol (Noisy-le-grand). 2017;63:122. 10.14715/cmb/2017.63.9.21
- Bogovič Matijašić B, Obermajer T, Lipoglavšek L, Sernel T, Locatelli I, et al. Effects of synbiotic fermented milk containing Lactobacillus acidophilus La-5 and Bifidobacterium animalis ssp. lactis BB-12 on the fecal microbiota of adults with irritable bowel syndrome: A randomized double-blind, placebo-controlled trial. J Dairy Sci. 2016;99:5008. 10.3168/jds.2015-10743
- Yoon H, Park YS, Lee DH, Seo JG, Shin CM, et al. Effect of administering a multi-species probiotic mixture on the changes in fecal microbiota and symptoms of irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Clin Biochem Nutr. 2015;57:129. 10.3164/jcbn.15-14
- Shanshal SA, Alsaaty MH, Al-Qazaz H, Al-Zidan RN. Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial. Ceska Slov Farm. 2024;73:233.
- Shin SY, Park S, Moon JM, Kim K, Kim JW, et al. Compositional Changes in the Gut Microbiota of Responders and Non-responders to Probiotic Treatment Among Patients With Diarrhea-predominant Irritable Bowel Syndrome: A Post Hoc Analysis of a Randomized Clinical Trial. J Neurogastroenterol Motil. 2022;28:642. 10.5056/jnm21202
- Yoon JS, Sohn W, Lee OY, Lee SP, Lee KN, et al. Effect of multispecies probiotics on irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Gastroenterol Hepatol. 2014;29:52. 10.1111/jgh.12322
- Chung HG, Min YW, Lee C, Hong SN, Won JY, et al. Effects of Novel Probiotics in a Murine Model of Irritable Bowel Syndrome. Korean J Gastroenterol. 2020;75:141. 10.4166/kjg.2020.75.3.141
- Ruiz-Sánchez C, Escudero-López B, Fernández-Pachón MS. Evaluation of the efficacy of probiotics as treatment in irritable bowel syndrome. Endocrinol Diabetes Nutr (Engl Ed). 2024;71:19. 10.1016/j.endien.2024.01.003
- Tomita T, Fukui H, Okugawa T, Nakanishi T, Mieno M, et al. Effect of G9-1 on the Intestinal Environment and Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)-like Symptoms in Patients with Quiescent Crohn's Disease: A Prospective Pilot Study. J Clin Med. 2023;12. 10.3390/jcm12103368
- Andresen V, Gschossmann J, Layer P. Heat-inactivated Bifidobacterium bifidum MIMBb75 (SYN-HI-001) in the treatment of irritable bowel syndrome: a multicentre, randomised, double-blind, placebo-controlled clinical trial. Lancet Gastroenterol Hepatol. 2020;5:658. 10.1016/S2468-1253(20)30056-X
- Guglielmetti S, Mora D, Gschwender M, Popp K. Randomised clinical trial: Bifidobacterium bifidum MIMBb75 significantly alleviates irritable bowel syndrome and improves quality of life--a double-blind, placebo-controlled study. Aliment Pharmacol Ther. 2011;33:1123. 10.1111/j.1365-2036.2011.04633.x
- Hong KS, Kang HW, Im JP, Ji GE, Kim SG, et al. Effect of probiotics on symptoms in korean adults with irritable bowel syndrome. Gut Liver. 2009;3:101. 10.5009/gnl.2009.3.2.101
- Williams EA, Stimpson J, Wang D, Plummer S, Garaiova I, et al. Clinical trial: a multistrain probiotic preparation significantly reduces symptoms of irritable bowel syndrome in a double-blind placebo-controlled study. Aliment Pharmacol Ther. 2009;29:97. 10.1111/j.1365-2036.2008.03848.x
- Yoon JY, Cha JM, Oh JK, Tan PL, Kim SH, et al. Probiotics Ameliorate Stool Consistency in Patients with Chronic Constipation: A Randomized, Double-Blind, Placebo-Controlled Study. Dig Dis Sci. 2018;63:2754. 10.1007/s10620-018-5139-8
- Ortiz-Lucas M, Tobías A, Saz P, Sebastián JJ. Effect of probiotic species on irritable bowel syndrome symptoms: A bring up to date meta-analysis. Rev Esp Enferm Dig. 2013;105:19.
- Ki Cha B, Mun Jung S, Hwan Choi C, Song ID, Woong Lee H, et al. The effect of a multispecies probiotic mixture on the symptoms and fecal microbiota in diarrhea-dominant irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Clin Gastroenterol. 2012;46:220. 10.1097/MCG.0b013e31823712b1
- Zeng J, Li YQ, Zuo XL, Zhen YB, Yang J, et al. Clinical trial: effect of active lactic acid bacteria on mucosal barrier function in patients with diarrhoea-predominant irritable bowel syndrome. Aliment Pharmacol Ther. 2008;28:994. 10.1111/j.1365-2036.2008.03818.x
- Drouault-Holowacz S, Bieuvelet S, Burckel A, Cazaubiel M, Dray X, et al. A double blind randomized controlled trial of a probiotic combination in 100 patients with irritable bowel syndrome. Gastroenterol Clin Biol. 2008;32:147. 10.1016/j.gcb.2007.06.001
- Astegiano M, Pellicano R, Terzi E, Simondi D, Rizzetto M. Treatment of irritable bowel syndrome. A case control experience. Minerva Gastroenterol Dietol. 2006;52:359.
- Brigidi P, Vitali B, Swennen E, Bazzocchi G, Matteuzzi D. Effects of probiotic administration upon the composition and enzymatic activity of human fecal microbiota in patients with irritable bowel syndrome or functional diarrhea. Res Microbiol. 2001;152:735.
