5/4/2025
Last update
5/4/2025
Reviewed By
Research Authors
Infographics 
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.1
USERS' SCORE
Good
Based on 4 Reviews
8.3
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol)
13 mcg (500 IU)
63%
Calcium (as Calcium Citrate)
630 mg
48%
Top Medical Research Studies
9
We explored the link between vitamin D3 and knee osteoarthritis (OA) by examining both young and older mice. Our findings revealed that a deficiency in vitamin D3, specifically the active form known as 1,25(OH)D, significantly sped up the development of age-related OA. This included issues such as cartilage damage and increased chondrocyte senescence.
When we supplemented with vitamin D3, we were pleased to see a reversal of these negative changes in OA phenotypes among the test mice. It not only improved cartilage health but also countered oxidative stress and cell aging associated with OA.
Our research highlights the important role of vitamin D3 in maintaining joint health and its potential to help prevent or slow down the onset of OA through mechanisms involving Sirt1, a gene linked to aging and cellular health. This suggests that ensuring sufficient levels of vitamin D3 could be a useful strategy for those at risk of developing arthritis.
When we supplemented with vitamin D3, we were pleased to see a reversal of these negative changes in OA phenotypes among the test mice. It not only improved cartilage health but also countered oxidative stress and cell aging associated with OA.
Our research highlights the important role of vitamin D3 in maintaining joint health and its potential to help prevent or slow down the onset of OA through mechanisms involving Sirt1, a gene linked to aging and cellular health. This suggests that ensuring sufficient levels of vitamin D3 could be a useful strategy for those at risk of developing arthritis.
8
We explored the impact of 1,25-Dihydroxyvitamin D, commonly known as vitamin D3, on rheumatoid arthritis (RA) and macrophage activity. Our research reveals that vitamin D3 can significantly suppress the activation of a particular type of immune cell known as M1 macrophages, which are often linked to inflammation and RA.
Specifically, vitamin D3 appears to reduce the expression of inflammatory markers like IL-6 and CXCL10 in the macrophages of RA patients. Through experiments with THP-1 cells—lab-induced macrophages— vitamin D3 was found to boost the expression of fructose-1,6-bisphosphatase 1 (FBP1), a protein that helps control immune responses by interacting with another protein called PKR.
Importantly, treatment with vitamin D3 not only diminished M1 macrophage activity but also led to improvements in arthritis symptoms in mice genetically predisposed to develop RA. This suggests that vitamin D3 could play a beneficial role in regulating macrophage function and alleviating the clinical signs of arthritis.
Overall, we are encouraged by these findings, as they provide a clearer understanding of how vitamin D3 can support the immune system and potentially aid individuals suffering from arthritis.
Specifically, vitamin D3 appears to reduce the expression of inflammatory markers like IL-6 and CXCL10 in the macrophages of RA patients. Through experiments with THP-1 cells—lab-induced macrophages— vitamin D3 was found to boost the expression of fructose-1,6-bisphosphatase 1 (FBP1), a protein that helps control immune responses by interacting with another protein called PKR.
Importantly, treatment with vitamin D3 not only diminished M1 macrophage activity but also led to improvements in arthritis symptoms in mice genetically predisposed to develop RA. This suggests that vitamin D3 could play a beneficial role in regulating macrophage function and alleviating the clinical signs of arthritis.
Overall, we are encouraged by these findings, as they provide a clearer understanding of how vitamin D3 can support the immune system and potentially aid individuals suffering from arthritis.
8
We investigated how vitamin D3 supplementation affects symptoms in patients dealing with knee osteoarthritis (OA). This was an open-label clinical trial conducted over three months, where participants received 4000 IU of vitamin D3 daily. We measured clinical responses at the beginning and after three months using specific assessment tools.
Our findings were promising, as we saw a notable drop in pain levels and improvements in stiffness and physical function based on patient reports. Out of the 80 patients who completed the study, an impressive 86.7% showed a positive response to treatment, indicating that vitamin D3 could play a beneficial role in managing OA symptoms.
Interestingly, while vitamin D3 supplementation raised serum levels of certain inflammatory markers, specifically IL-33, it also led to significant reductions in other pro-inflammatory cytokines like TNF-α and IL-17. No adverse effects were reported during the trial, underscoring the safety profile of vitamin D3.
In conclusion, our results suggest that vitamin D3 is a promising option for easing symptoms in knee OA, and further research is warranted to explore the implications of altered inflammatory markers in the disease process.
Our findings were promising, as we saw a notable drop in pain levels and improvements in stiffness and physical function based on patient reports. Out of the 80 patients who completed the study, an impressive 86.7% showed a positive response to treatment, indicating that vitamin D3 could play a beneficial role in managing OA symptoms.
Interestingly, while vitamin D3 supplementation raised serum levels of certain inflammatory markers, specifically IL-33, it also led to significant reductions in other pro-inflammatory cytokines like TNF-α and IL-17. No adverse effects were reported during the trial, underscoring the safety profile of vitamin D3.
In conclusion, our results suggest that vitamin D3 is a promising option for easing symptoms in knee OA, and further research is warranted to explore the implications of altered inflammatory markers in the disease process.
Most Useful Reviews
9
Helps with osteoarthritis
Excellent! This citrate formula genuinely aids with osteoarthritis. I buy it regularly; however, it's disappointing that the 1kg cans have been discontinued, leaving only smaller sizes available.
7.5
Joint support agent
I've been using this remedy for several years for the comprehensive maintenance of my joints due to rheumatoid arthritis. It truly works and complements the primary treatment as a joint support agent. I highly recommend it.
7.5
Reduced joint symptoms
I ordered this for my father, who suffers from rheumatoid arthritis. During flare-ups, his joints become very sore and swollen. After taking these for two months, his symptoms nearly vanished, although they returned later, prompting me to purchase it again. I hope this calcium continues to provide such positive results. My father also takes an additional vitamin D3 supplement due to its low content in this complex.
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.1
- All Researches
9
We conducted an insightful study to explore how vitamin D3 supplementation might affect rheumatoid arthritis (RA) symptoms, particularly focusing on disease activity and fatigue. This research involved a total of 68 RA patients who were monitored over a period of 12 weeks.
Our participants were divided into two groups. One group received a weekly dose of 50,000 IU of vitamin D3 alongside their conventional arthritis medications. The other group continued with their standard treatment regimen without any vitamin D3.
As we evaluated the outcomes, we found that the group receiving vitamin D3 exhibited significant improvements. Specifically, they showed enhanced levels of vitamin D and reported lower fatigue, as measured by the FACIT-F score. While both groups initially presented similar health characteristics, those on vitamin D3 achieved a normal range in fatigue levels compared to the continued struggle within the other group.
Interestingly, we observed a positive correlation between higher vitamin D levels and improved fatigue scores, indicating that vitamin D3 could indeed play a beneficial role in managing symptoms associated with rheumatoid arthritis. However, disease activity scores did not show a strong significant correlation with vitamin D levels, suggesting that more research may be necessary to understand this relationship fully.
Our participants were divided into two groups. One group received a weekly dose of 50,000 IU of vitamin D3 alongside their conventional arthritis medications. The other group continued with their standard treatment regimen without any vitamin D3.
As we evaluated the outcomes, we found that the group receiving vitamin D3 exhibited significant improvements. Specifically, they showed enhanced levels of vitamin D and reported lower fatigue, as measured by the FACIT-F score. While both groups initially presented similar health characteristics, those on vitamin D3 achieved a normal range in fatigue levels compared to the continued struggle within the other group.
Interestingly, we observed a positive correlation between higher vitamin D levels and improved fatigue scores, indicating that vitamin D3 could indeed play a beneficial role in managing symptoms associated with rheumatoid arthritis. However, disease activity scores did not show a strong significant correlation with vitamin D levels, suggesting that more research may be necessary to understand this relationship fully.
9
We explored the link between vitamin D3 and knee osteoarthritis (OA) by examining both young and older mice. Our findings revealed that a deficiency in vitamin D3, specifically the active form known as 1,25(OH)D, significantly sped up the development of age-related OA. This included issues such as cartilage damage and increased chondrocyte senescence.
When we supplemented with vitamin D3, we were pleased to see a reversal of these negative changes in OA phenotypes among the test mice. It not only improved cartilage health but also countered oxidative stress and cell aging associated with OA.
Our research highlights the important role of vitamin D3 in maintaining joint health and its potential to help prevent or slow down the onset of OA through mechanisms involving Sirt1, a gene linked to aging and cellular health. This suggests that ensuring sufficient levels of vitamin D3 could be a useful strategy for those at risk of developing arthritis.
When we supplemented with vitamin D3, we were pleased to see a reversal of these negative changes in OA phenotypes among the test mice. It not only improved cartilage health but also countered oxidative stress and cell aging associated with OA.
Our research highlights the important role of vitamin D3 in maintaining joint health and its potential to help prevent or slow down the onset of OA through mechanisms involving Sirt1, a gene linked to aging and cellular health. This suggests that ensuring sufficient levels of vitamin D3 could be a useful strategy for those at risk of developing arthritis.
9
We investigated the potential of 2D layered calcium disilicide nanoparticles (CSNs) to treat rheumatoid arthritis (RA) through their unique properties. CSNs are crafted using a straightforward method of aqueous exfoliation, and their hydrolysis generates several beneficial components including hydrogen gas, alkaline calcium hydroxide (Ca(OH)), and silica.
These components support healing by improving anti-oxidation and reducing inflammation while promoting bone regeneration. The hydrogen gas helps eliminate harmful radicals and can alter macrophage behavior, which is crucial for regulating inflammation. Meanwhile, calcium hydroxide works to balance the acidic environment in the joints, limiting the harmful activity of osteoclasts, the cells that break down bone.
Furthermore, the calcium released can bind with phosphates, aiding in the formation of calcium phosphate, which is essential for bone mineralization. We confirmed these multifaceted benefits through tests on arthritic mice and rabbits, demonstrating that CSNs can provide a promising, biocompatible treatment strategy that enhances therapy beyond just addressing inflammation.
This study emphasizes the importance of calcium and its interactive role in more comprehensive arthritis treatments, fostering both anti-inflammatory and pro-osteogenic effects vital for joint health.
These components support healing by improving anti-oxidation and reducing inflammation while promoting bone regeneration. The hydrogen gas helps eliminate harmful radicals and can alter macrophage behavior, which is crucial for regulating inflammation. Meanwhile, calcium hydroxide works to balance the acidic environment in the joints, limiting the harmful activity of osteoclasts, the cells that break down bone.
Furthermore, the calcium released can bind with phosphates, aiding in the formation of calcium phosphate, which is essential for bone mineralization. We confirmed these multifaceted benefits through tests on arthritic mice and rabbits, demonstrating that CSNs can provide a promising, biocompatible treatment strategy that enhances therapy beyond just addressing inflammation.
This study emphasizes the importance of calcium and its interactive role in more comprehensive arthritis treatments, fostering both anti-inflammatory and pro-osteogenic effects vital for joint health.
8
Calcitriol impacts immune response in RA
We explored the effects of calcitriol, the active form of vitamin D3, on mesenchymal stem cells (MSCs) and their potential to influence rheumatoid arthritis (RA) in a mouse model. Using a well-structured study design, we induced RA in BALB/c mice and divided them into three groups: one group received untreated MSCs, another received calcitriol-treated MSCs, while the third group received no treatment at all. After the treatment, we assessed various immune responses and inflammatory mediators.
Our findings revealed that the calcitriol-treated MSCs significantly outperformed untreated MSCs in regulating immune responses. Specifically, we noted improvements in the function of innate immune cells, particularly splenocytes. These cells showed enhanced regulatory abilities, which led to a decrease in pro-inflammatory cytokines like IL-17 and an increase in anti-inflammatory cytokines such as IL-4 and IL-10. This suggests that calcitriol may play a crucial role in modulating the immune response in RA.
However, while the study shows encouraging results for calcitriol-treated MSCs in reducing inflammation, it’s important to note that this research is still in the early stages and primarily conducted in a controlled laboratory environment. Further studies are needed to determine how these findings translate to human treatment outcomes.
Our findings revealed that the calcitriol-treated MSCs significantly outperformed untreated MSCs in regulating immune responses. Specifically, we noted improvements in the function of innate immune cells, particularly splenocytes. These cells showed enhanced regulatory abilities, which led to a decrease in pro-inflammatory cytokines like IL-17 and an increase in anti-inflammatory cytokines such as IL-4 and IL-10. This suggests that calcitriol may play a crucial role in modulating the immune response in RA.
However, while the study shows encouraging results for calcitriol-treated MSCs in reducing inflammation, it’s important to note that this research is still in the early stages and primarily conducted in a controlled laboratory environment. Further studies are needed to determine how these findings translate to human treatment outcomes.
8
We investigated the effects of vitamin D3 on arthritis, particularly focusing on its potential to influence the NF-κB pathway, a key player in the development of osteoarthritis (OA). Our findings revealed that vitamin D3 significantly protects against OA symptoms by stabilizing NF-κB, an important transcription factor involved in inflammation.
Through a series of experiments, including analysis of protein levels and gene expression in both living models and isolated cells, we observed that vitamin D3 helps to inhibit the phosphorylation and nuclear translocation of NF-κB. This means that vitamin D3 could effectively prevent this factor from entering the nucleus of chondrocytes—cells crucial for cartilage health—where it could drive damaging inflammatory processes.
We also found that vitamin D3 promotes a process called autophagy in chondrocytes. This process helps maintain cellular health by clearing out damaged components. Our study reinforced the idea that vitamin D3 not only acts through the vitamin D receptor but also significantly impacts the AMPK/mTOR signaling pathway, further supporting its role in managing arthritis.
Overall, our research underscores the beneficial effects of vitamin D3 on arthritis, suggesting that enhancing vitamin D levels might be a valuable strategy in OA treatment.
Through a series of experiments, including analysis of protein levels and gene expression in both living models and isolated cells, we observed that vitamin D3 helps to inhibit the phosphorylation and nuclear translocation of NF-κB. This means that vitamin D3 could effectively prevent this factor from entering the nucleus of chondrocytes—cells crucial for cartilage health—where it could drive damaging inflammatory processes.
We also found that vitamin D3 promotes a process called autophagy in chondrocytes. This process helps maintain cellular health by clearing out damaged components. Our study reinforced the idea that vitamin D3 not only acts through the vitamin D receptor but also significantly impacts the AMPK/mTOR signaling pathway, further supporting its role in managing arthritis.
Overall, our research underscores the beneficial effects of vitamin D3 on arthritis, suggesting that enhancing vitamin D levels might be a valuable strategy in OA treatment.
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Helps with osteoarthritis
Excellent! This citrate formula genuinely aids with osteoarthritis. I buy it regularly; however, it's disappointing that the 1kg cans have been discontinued, leaving only smaller sizes available.
7.5
Joint support agent
I've been using this remedy for several years for the comprehensive maintenance of my joints due to rheumatoid arthritis. It truly works and complements the primary treatment as a joint support agent. I highly recommend it.
7.5
Reduced joint symptoms
I ordered this for my father, who suffers from rheumatoid arthritis. During flare-ups, his joints become very sore and swollen. After taking these for two months, his symptoms nearly vanished, although they returned later, prompting me to purchase it again. I hope this calcium continues to provide such positive results. My father also takes an additional vitamin D3 supplement due to its low content in this complex.
7.5
Calcium for polyarthritis
A good, easily absorbed calcium form that does not cause kidney stones. My mother has polyarthritis, and she must consistently take calcium. It's a good price, and I recommend it.
Frequently Asked Questions
7.5
Reduced joint symptoms
I ordered this for my father, who suffers from rheumatoid arthritis. During flare-ups, his joints become very sore and swollen. After taking these for two months, his symptoms nearly vanished, although they returned later, prompting me to purchase it again. I hope this calcium continues to provide such positive results. My father also takes an additional vitamin D3 supplement due to its low content in this complex.
7.5
Joint support agent
I've been using this remedy for several years for the comprehensive maintenance of my joints due to rheumatoid arthritis. It truly works and complements the primary treatment as a joint support agent. I highly recommend it.
9
Helps with osteoarthritis
Excellent! This citrate formula genuinely aids with osteoarthritis. I buy it regularly; however, it's disappointing that the 1kg cans have been discontinued, leaving only smaller sizes available.
7.5
Calcium for polyarthritis
A good, easily absorbed calcium form that does not cause kidney stones. My mother has polyarthritis, and she must consistently take calcium. It's a good price, and I recommend it.
9
We conducted an insightful study to explore how vitamin D3 supplementation might affect rheumatoid arthritis (RA) symptoms, particularly focusing on disease activity and fatigue. This research involved a total of 68 RA patients who were monitored over a period of 12 weeks.
Our participants were divided into two groups. One group received a weekly dose of 50,000 IU of vitamin D3 alongside their conventional arthritis medications. The other group continued with their standard treatment regimen without any vitamin D3.
As we evaluated the outcomes, we found that the group receiving vitamin D3 exhibited significant improvements. Specifically, they showed enhanced levels of vitamin D and reported lower fatigue, as measured by the FACIT-F score. While both groups initially presented similar health characteristics, those on vitamin D3 achieved a normal range in fatigue levels compared to the continued struggle within the other group.
Interestingly, we observed a positive correlation between higher vitamin D levels and improved fatigue scores, indicating that vitamin D3 could indeed play a beneficial role in managing symptoms associated with rheumatoid arthritis. However, disease activity scores did not show a strong significant correlation with vitamin D levels, suggesting that more research may be necessary to understand this relationship fully.
Our participants were divided into two groups. One group received a weekly dose of 50,000 IU of vitamin D3 alongside their conventional arthritis medications. The other group continued with their standard treatment regimen without any vitamin D3.
As we evaluated the outcomes, we found that the group receiving vitamin D3 exhibited significant improvements. Specifically, they showed enhanced levels of vitamin D and reported lower fatigue, as measured by the FACIT-F score. While both groups initially presented similar health characteristics, those on vitamin D3 achieved a normal range in fatigue levels compared to the continued struggle within the other group.
Interestingly, we observed a positive correlation between higher vitamin D levels and improved fatigue scores, indicating that vitamin D3 could indeed play a beneficial role in managing symptoms associated with rheumatoid arthritis. However, disease activity scores did not show a strong significant correlation with vitamin D levels, suggesting that more research may be necessary to understand this relationship fully.
8
We explored the impact of 1,25-Dihydroxyvitamin D, commonly known as vitamin D3, on rheumatoid arthritis (RA) and macrophage activity. Our research reveals that vitamin D3 can significantly suppress the activation of a particular type of immune cell known as M1 macrophages, which are often linked to inflammation and RA.
Specifically, vitamin D3 appears to reduce the expression of inflammatory markers like IL-6 and CXCL10 in the macrophages of RA patients. Through experiments with THP-1 cells—lab-induced macrophages— vitamin D3 was found to boost the expression of fructose-1,6-bisphosphatase 1 (FBP1), a protein that helps control immune responses by interacting with another protein called PKR.
Importantly, treatment with vitamin D3 not only diminished M1 macrophage activity but also led to improvements in arthritis symptoms in mice genetically predisposed to develop RA. This suggests that vitamin D3 could play a beneficial role in regulating macrophage function and alleviating the clinical signs of arthritis.
Overall, we are encouraged by these findings, as they provide a clearer understanding of how vitamin D3 can support the immune system and potentially aid individuals suffering from arthritis.
Specifically, vitamin D3 appears to reduce the expression of inflammatory markers like IL-6 and CXCL10 in the macrophages of RA patients. Through experiments with THP-1 cells—lab-induced macrophages— vitamin D3 was found to boost the expression of fructose-1,6-bisphosphatase 1 (FBP1), a protein that helps control immune responses by interacting with another protein called PKR.
Importantly, treatment with vitamin D3 not only diminished M1 macrophage activity but also led to improvements in arthritis symptoms in mice genetically predisposed to develop RA. This suggests that vitamin D3 could play a beneficial role in regulating macrophage function and alleviating the clinical signs of arthritis.
Overall, we are encouraged by these findings, as they provide a clearer understanding of how vitamin D3 can support the immune system and potentially aid individuals suffering from arthritis.
8
We investigated how vitamin D3 supplementation affects symptoms in patients dealing with knee osteoarthritis (OA). This was an open-label clinical trial conducted over three months, where participants received 4000 IU of vitamin D3 daily. We measured clinical responses at the beginning and after three months using specific assessment tools.
Our findings were promising, as we saw a notable drop in pain levels and improvements in stiffness and physical function based on patient reports. Out of the 80 patients who completed the study, an impressive 86.7% showed a positive response to treatment, indicating that vitamin D3 could play a beneficial role in managing OA symptoms.
Interestingly, while vitamin D3 supplementation raised serum levels of certain inflammatory markers, specifically IL-33, it also led to significant reductions in other pro-inflammatory cytokines like TNF-α and IL-17. No adverse effects were reported during the trial, underscoring the safety profile of vitamin D3.
In conclusion, our results suggest that vitamin D3 is a promising option for easing symptoms in knee OA, and further research is warranted to explore the implications of altered inflammatory markers in the disease process.
Our findings were promising, as we saw a notable drop in pain levels and improvements in stiffness and physical function based on patient reports. Out of the 80 patients who completed the study, an impressive 86.7% showed a positive response to treatment, indicating that vitamin D3 could play a beneficial role in managing OA symptoms.
Interestingly, while vitamin D3 supplementation raised serum levels of certain inflammatory markers, specifically IL-33, it also led to significant reductions in other pro-inflammatory cytokines like TNF-α and IL-17. No adverse effects were reported during the trial, underscoring the safety profile of vitamin D3.
In conclusion, our results suggest that vitamin D3 is a promising option for easing symptoms in knee OA, and further research is warranted to explore the implications of altered inflammatory markers in the disease process.
References
- Rafati A, Ramezani R, Esmaeili Gouvarchin Ghaleh H, Bahrami S, Alvanegh AG, et al. Calcitriol Treated Mesenchymal Stem Cells Modulated Immune Response in Collagen-Induced Rheumatoid Arthritis in BALB/c Mice. Transplant Proc. 2025;57:355. 10.1016/j.transproceed.2024.12.020
- Liu P, Zhou J, Cui H, Xu J, Ruan G, et al. 1,25(OH)D induces chondrocyte autophagy and reduces the loss of proteoglycans in osteoarthritis through inhibiting the NF-κB pathway. Clin Rheumatol. 2025;44:811. 10.1007/s10067-024-07281-z
- Wielińska J, Górna K, Świerkot J, Bugaj B, Kolossa K, et al. Polymorphic Variants in the Vitamin D Receptor and Clinical Parameters of Rheumatoid Arthritis Patients Undergoing Anti-TNF Treatment. Arch Immunol Ther Exp (Warsz). 2024;72. 10.2478/aite-2024-0023
- Elfituri S. The effects of vitamin D supplementation on disease activity and fatigue in Libyan rheumatoid arthritis patients. Reumatologia. 2024;62:109. 10.5114/reum/187391
- Kim S, Chen N, Reid P. Current and future advances in practice: aromatase inhibitor-induced arthralgia. Rheumatol Adv Pract. 2024;8:rkae024. 10.1093/rap/rkae024
- Tekeli SÖ, Köse Ö, Yapar D, Tekeli FY, Asoğlu MM, et al. Relationship between serum vitamin D levels and the prevalence of knee osteoarthritis: A retrospective study on 3424 subjects. Technol Health Care. 2024;32:3649. 10.3233/THC-230802
- Huovinen J, Palosaari S, Pesonen P, Huhtakangas JA, Lehenkari P. 1,25(OH)D and its analogue calcipotriol inhibit the migration of human synovial and mesenchymal stromal cells in a wound healing model - A comparison with glucocorticoids. J Steroid Biochem Mol Biol. 2023;233:106373. 10.1016/j.jsbmb.2023.106373
- Zhu W, Zhu Y, Zhang S, Zhang W, Si Z, et al. 1,25-Dihydroxyvitamin D regulates macrophage activation through FBP1/PKR and ameliorates arthritis in TNF-transgenic mice. J Steroid Biochem Mol Biol. 2023;228:106251. 10.1016/j.jsbmb.2023.106251
- Chen J, Zhang J, Li J, Qin R, Lu N, et al. 1,25-Dihydroxyvitamin D Deficiency Accelerates Aging-related Osteoarthritis via Downregulation of Sirt1 in Mice. Int J Biol Sci. 2023;19:610. 10.7150/ijbs.78785
- Divjak A, Jovanovic I, Matic A, Lucic AT, Gajovic N, et al. The influence of vitamin D supplementation on the expression of mediators of inflammation in knee osteoarthritis. Immunol Res. 2023;71:442. 10.1007/s12026-022-09354-0
- Ji P, Qiu S, Huang J, Wang L, Wang Y, et al. Hydrolysis of 2D Nanosheets Reverses Rheumatoid Arthritis Through Anti-Inflammation and Osteogenesis. Adv Mater. 2025;37:e2415543. 10.1002/adma.202415543
