Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 78 Reviews
8.1
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol)
13 mcg (500 IU)
63%
Calcium (as Calcium Citrate)
630 mg
48%
Top Medical Research Studies
8
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
Read More
8
We explored a unique case of a 3-year-old Iranian girl with Juvenile Paget's disease (JPD) linked to a new mutation and vitamin D deficiency. This rare condition led to her experiencing significant bone pain, fractures, and deformities from an early age.
Our findings revealed that she had a unique mutation in the TNFRSF11B gene, which contributes to OPG deficiency. Remarkably, she showed improvement following treatment with oral vitamin D and intravenous pamidronate. This case highlights both the impact of genetic factors and the importance of vitamin D in managing JPD effectively.
Our findings revealed that she had a unique mutation in the TNFRSF11B gene, which contributes to OPG deficiency. Remarkably, she showed improvement following treatment with oral vitamin D and intravenous pamidronate. This case highlights both the impact of genetic factors and the importance of vitamin D in managing JPD effectively.
Read More
Most Useful Reviews
7.5
Bone fusion success
174 people found this helpful
A few months ago, I suffered a compound fracture in my leg, which required an operation. I used calcium supplements in chelate form during my recovery, and by the third month, my X-ray showed good bone healing. The doctor allowed me to remove the cast early. Now, I’ve switched to calcium citrate, and I’m pleased with the results. After two weeks of using it, my ability to walk has significantly improved. I continue to heal and strengthen my bones.
Read More
9
Morning pain relief
162 people found this helpful
I recommend this product for anyone with a calcium deficiency. It offers a good price-to-quality ratio, has no unpleasant aftertaste, and I experienced no side effects. My bone pain and lower back issues have decreased, making mornings much better.
Read More
9
No side effects
117 people found this helpful
Excellent! I take this particular calcium as it absorbs easily, and I have concerns about my stool when taking calcium supplements. This brand has produced no side effects. I’m satisfied with its quality and the neutral taste. Many suffer from calcium deficiency, so it’s important to monitor this.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
- All Researches
8
We explored a unique case of a 3-year-old Iranian girl with Juvenile Paget's disease (JPD) linked to a new mutation and vitamin D deficiency. This rare condition led to her experiencing significant bone pain, fractures, and deformities from an early age.
Our findings revealed that she had a unique mutation in the TNFRSF11B gene, which contributes to OPG deficiency. Remarkably, she showed improvement following treatment with oral vitamin D and intravenous pamidronate. This case highlights both the impact of genetic factors and the importance of vitamin D in managing JPD effectively.
Our findings revealed that she had a unique mutation in the TNFRSF11B gene, which contributes to OPG deficiency. Remarkably, she showed improvement following treatment with oral vitamin D and intravenous pamidronate. This case highlights both the impact of genetic factors and the importance of vitamin D in managing JPD effectively.
Read More
8
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
Read More
User Reviews
USERS' SCORE
Good
Based on 78 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Bone fusion success
174 people found this helpful
A few months ago, I suffered a compound fracture in my leg, which required an operation. I used calcium supplements in chelate form during my recovery, and by the third month, my X-ray showed good bone healing. The doctor allowed me to remove the cast early. Now, I’ve switched to calcium citrate, and I’m pleased with the results. After two weeks of using it, my ability to walk has significantly improved. I continue to heal and strengthen my bones.
Read More
9
Morning pain relief
162 people found this helpful
I recommend this product for anyone with a calcium deficiency. It offers a good price-to-quality ratio, has no unpleasant aftertaste, and I experienced no side effects. My bone pain and lower back issues have decreased, making mornings much better.
Read More
9
No side effects
117 people found this helpful
Excellent! I take this particular calcium as it absorbs easily, and I have concerns about my stool when taking calcium supplements. This brand has produced no side effects. I’m satisfied with its quality and the neutral taste. Many suffer from calcium deficiency, so it’s important to monitor this.
Read More
9
Reduces pain
117 people found this helpful
This vitamin worked well for my mother's hand pain; after taking it, her pain disappeared. Although the composition isn't the best, it remains affordable.
Read More
9
Pain relief success
19 people found this helpful
I ordered this due to its price, not expecting much. I had shoulder joint pain that hindered daily activities. Amazingly, after two weeks of taking calcium, I realised my bone pain had disappeared. I highly recommend it; it truly works!
Read More
Frequently Asked Questions
9
Pain relief success
19 people found this helpful
I ordered this due to its price, not expecting much. I had shoulder joint pain that hindered daily activities. Amazingly, after two weeks of taking calcium, I realised my bone pain had disappeared. I highly recommend it; it truly works!
9
Pain relief achieved
2 people found this helpful
Great size, good doses. My mother experienced leg pain due to bone pain. After investigating, we discovered osteoporosis. I ordered these tablets for their better absorption compared to carbonate, along with included vitamin D for calcium absorption. The pain diminished within a day and disappeared after a week. I took one tablet twice daily for a month. Pain did not return after a two-month break. This is an effective product, and I buy it at discounts for the whole family.
7.5
Bone fusion success
174 people found this helpful
A few months ago, I suffered a compound fracture in my leg, which required an operation. I used calcium supplements in chelate form during my recovery, and by the third month, my X-ray showed good bone healing. The doctor allowed me to remove the cast early. Now, I’ve switched to calcium citrate, and I’m pleased with the results. After two weeks of using it, my ability to walk has significantly improved. I continue to heal and strengthen my bones.
9
Improved back condition
3 people found this helpful
This calcium has greatly benefitted my mother, aged 67, who had difficulty straightening her back due to osteochondrosis. After three months, her back is straightened, and she feels lighter. We've also added vitamin K2 for additional bone benefits. We’re happy to continue using this product.
9
Stronger teeth
2 people found this helpful
After completing a course of this calcium, my joint pains have vanished, and my teeth feel stronger than ever. Calcium citrate absorbs perfectly for me, whereas calcium carbonate caused discomfort. I highly recommend this product!
9
Eliminated bone pain
3 people found this helpful
The pain in my bones has disappeared since I started this supplement. I had a vitamin D deficiency, so I took extra vitamin D along with it, and now all is well. I take two easy-to-swallow pills a day and hope you benefit as much as I have!
9
Muscle relief
1 people found this helpful
I purchased this supplement to alleviate chronic muscular issues stemming from overuse and nutritional deficiency, and it has worked wonders alongside my magnesium routine. I've noticed less muscle pain and cramps, providing relief from bone pain too, with no side effects.
9
Essential for osteoporosis
1 people found this helpful
On my doctor's advice, I started taking calcium, as citrate is the safest form. It's a blessing to find this calcium at an affordable price, complete with Vitamin D. It's crucial for preventing osteoporosis and advantageous for my teeth. Highly recommend for bone health.
8
We explored a unique case of a 3-year-old Iranian girl with Juvenile Paget's disease (JPD) linked to a new mutation and vitamin D deficiency. This rare condition led to her experiencing significant bone pain, fractures, and deformities from an early age.
Our findings revealed that she had a unique mutation in the TNFRSF11B gene, which contributes to OPG deficiency. Remarkably, she showed improvement following treatment with oral vitamin D and intravenous pamidronate. This case highlights both the impact of genetic factors and the importance of vitamin D in managing JPD effectively.
Our findings revealed that she had a unique mutation in the TNFRSF11B gene, which contributes to OPG deficiency. Remarkably, she showed improvement following treatment with oral vitamin D and intravenous pamidronate. This case highlights both the impact of genetic factors and the importance of vitamin D in managing JPD effectively.
8
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
References
- Saki F, Karamizadeh Z, Nasirabadi S, Mumm S, McAlister WH, et al. Juvenile paget's disease in an Iranian kindred with vitamin D deficiency and novel homozygous TNFRSF11B mutation. J Bone Miner Res. 2013;28:1501. 10.1002/jbmr.1868
- von Brackel FN, Grambeck J, Barvencik F, Amling M, Oheim R. In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution. JBMR Plus. 2024;8:ziae139. 10.1093/jbmrpl/ziae139
