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Specifically, we found that 1,25-(OH)D not only extends the growth phase of hair follicles but also improves the abilities of certain skin cells that are vital for hair growth. This process relies on receptors for vitamin D, highlighting the importance of our body’s biological pathways in managing hair health.
Interestingly, our findings showed that 1,25-(OH)D can also negate some of the negative effects of DHT—a hormone often linked to hair loss. Overall, this suggests that vitamin D3 could be an effective treatment option for those experiencing androgenetic alopecia, or common hair loss.
After treatment, we assessed the participants' hair growth condition 15 days following their last dose. We found that the average age of the women was 32.2 years, with the age group of 21-30 exhibiting a higher prevalence of TE than those aged 31-40.
Remarkably, 82.5% of the women experienced significant improvement in hair growth after the treatment. We observed that younger women who do not use sunscreen but often consume milk or milk protein showed particularly notable results. This suggests that vitamin D could be a promising option for those struggling with hair loss due to TE.
To promote hair growth, both patients were given dietary supplementation of vitamin D3 at a dose of 1000 IU daily. Over a treatment period of 3 to 4 months, we noted significant improvements in both patients. This was evidenced by a reduction in hair loss linked to their obsessive-compulsive disorder, which corresponded with increases in their serum 25-hydroxyvitamin D levels.
The results suggest there's a potential connection between vitamin D deficiency and trichotillomania, particularly how inadequate vitamin D may exacerbate hair loss in those susceptible to this disorder. Overall, we found support in both experimental and clinical evidence for the role vitamin D may play in hair loss associated with trichotillomania.
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Specifically, we found that 1,25-(OH)D not only extends the growth phase of hair follicles but also improves the abilities of certain skin cells that are vital for hair growth. This process relies on receptors for vitamin D, highlighting the importance of our body’s biological pathways in managing hair health.
Interestingly, our findings showed that 1,25-(OH)D can also negate some of the negative effects of DHT—a hormone often linked to hair loss. Overall, this suggests that vitamin D3 could be an effective treatment option for those experiencing androgenetic alopecia, or common hair loss.
Over the course of the study, we initiated a regimen that started with a six-month course of vitamin D3 repletion using oral cholecalciferol, which did not yield immediate results. However, upon switching to calcitriol and its analog, paricalcitol, two out of the three girls experienced significant hair regrowth. One girl saw hair begin to regrow within six months, and her progress stabilized over the next four years with increased doses.
The second patient faced some side effects, such as mild hypercalcemia when taking calcitriol, which we successfully managed by transitioning to paricalcitol. Meanwhile, our third patient experienced a rapid resolution of hair loss with a high dose of cholecalciferol. These findings suggest that vitamin D may hold promise as a therapeutic option in managing specific types of alopecia, warranting further study in larger clinical trials.
After treatment, we assessed the participants' hair growth condition 15 days following their last dose. We found that the average age of the women was 32.2 years, with the age group of 21-30 exhibiting a higher prevalence of TE than those aged 31-40.
Remarkably, 82.5% of the women experienced significant improvement in hair growth after the treatment. We observed that younger women who do not use sunscreen but often consume milk or milk protein showed particularly notable results. This suggests that vitamin D could be a promising option for those struggling with hair loss due to TE.
To promote hair growth, both patients were given dietary supplementation of vitamin D3 at a dose of 1000 IU daily. Over a treatment period of 3 to 4 months, we noted significant improvements in both patients. This was evidenced by a reduction in hair loss linked to their obsessive-compulsive disorder, which corresponded with increases in their serum 25-hydroxyvitamin D levels.
The results suggest there's a potential connection between vitamin D deficiency and trichotillomania, particularly how inadequate vitamin D may exacerbate hair loss in those susceptible to this disorder. Overall, we found support in both experimental and clinical evidence for the role vitamin D may play in hair loss associated with trichotillomania.
Throughout the study, we measured participants' progress using clinical evaluations and a scoring system to gauge hair regrowth. Interestingly, both the vitamin D3 and bimatoprost groups showed significant improvements in hair regrowth compared to the microneedling-only group. However, after three months, we found no notable difference between the regrowth achieved with vitamin D3 and that with bimatoprost.
Importantly, all treatments were well tolerated, with only mild and temporary side effects reported. This leads us to conclude that while vitamin D3 in combination with microneedling offers a promising approach for localized AA, its benefits may not be significantly greater than those of bimatoprost.
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Frequently Asked Questions
Hair loss, also known as alopecia, is a common condition that affects both men and women, characterized by the thinning or complete loss of hair from the scalp or other areas of the body. It can occur due to various factors, including genetics, hormonal changes, medical conditions, and environmental factors. The most prevalent type of hair loss is androgenetic alopecia, often referred to as male or female pattern baldness, which typically results in a receding hairline or thinning crown in men and overall thinning in women.
In addition to genetic predisposition, hair loss can be triggered by stress, poor diet, certain medications, and underlying health issues such as thyroid disorders or autoimmune diseases. There are various treatment options available, ranging from over-the-counter products like minoxidil to prescription medications and hair restoration procedures, depending on the severity and cause of hair loss. It's crucial to consult with a healthcare professional to determine the most appropriate treatment plan tailored to individual needs and conditions.
Calcium Plus Vitamin D is a dietary supplement that combines calcium, an essential mineral vital for maintaining strong bones and teeth, with Vitamin D, a nutrient that enhances calcium absorption in the body. This combination is particularly beneficial for individuals looking to support their bone health, especially those at risk for osteoporosis or conditions that lead to decreased bone density. Calcium plays a key role in various bodily functions, including muscle contraction and nerve signaling, while Vitamin D aids in the regulation of calcium levels within the blood and helps promote overall immune function.
Many formulations of Calcium Plus Vitamin D are available in various forms, including tablets, capsules, and chewables, catering to different preferences and dietary needs. When considering adding a calcium and vitamin D supplement to your daily routine, it's essential to consult with a healthcare professional to ensure it's appropriate for your specific health requirements and to determine the right dosage. A balanced diet combined with regular sunlight exposure can also help maintain adequate calcium and vitamin D levels without the need for supplementation. However, for individuals who have limited sun exposure or have dietary restrictions, such supplements can provide a convenient and effective way to support bone health.
The relationship between calcium, vitamin D, and hair loss is a nuanced one. Vitamin D plays a significant role in various bodily functions, including the hair growth cycle. Studies suggest that a deficiency in vitamin D can lead to hair thinning and loss, particularly in conditions like alopecia areata. Therefore, supplementing with vitamin D may help improve hair health for individuals who are deficient. Calcium, on the other hand, is essential for overall health and supports bone and dental health, but its direct impact on hair loss is not as well established. It’s crucial to maintain a balanced intake of both nutrients for general health, which may indirectly benefit hair growth.
If you are considering calcium plus vitamin D supplements to address hair loss, it's advisable to consult with a healthcare provider first. They can assess your specific nutritional needs, check for deficiencies, and recommend the most effective approach for your situation. It's worth noting that hair loss can be influenced by various factors including genetics, stress, and hormonal changes, so addressing these root causes is essential for effective management.
Based on user reviews, individuals taking this calcium supplement for hair loss generally report observing results within a few weeks to two months. For instance, one reviewer mentioned noticeable improvements in hair strength and thickness after just three weeks of use (Read Review). Another user, who followed a two-month treatment plan, saw a significant reduction in hair loss (Read Review).
In some cases, users experienced benefits even sooner; one reported a significant reduction in hair loss after just one month of using the supplement (Read Review). Overall, while results can vary, many customers express satisfaction with the effectiveness of the supplement within a relatively short timeframe, often highlighting improvements during the first month or two of consistent use.
Scientific research supports the use of vitamin D3 as a potential treatment for various types of hair loss. A study involving 120 patients revealed that 79.17% were vitamin D3 deficient, linking this deficiency to conditions like male and female pattern hair loss, alopecia areata, and telogen effluvium [1]. Moreover, another investigation showed that patients receiving intralesional vitamin D3 injections for patchy alopecia areata reported satisfaction and fewer side effects compared to other treatments, indicating that vitamin D3 could be a safer option for treating this condition [2].
Further research has indicated that a potent form of vitamin D3 enhances hair regeneration and counteracts negative effects associated with hormones linked to hair loss, suggesting its potential effectiveness in addressing androgenetic alopecia [3]. Studies have also demonstrated significant improvements in hair growth among women taking vitamin D supplements, particularly in cases of telogen effluvium, where 82.5% of participants experienced positive results [1]. While more research is needed, these findings collectively suggest that incorporating vitamin D3 into treatment regimens could be beneficial for individuals experiencing various forms of hair loss.
Users report a variety of improvements in symptoms after taking the calcium supplement, particularly in relation to hair loss, which seems to be especially relevant for those who have recently given birth. Many individuals have noted significant reductions in hair shedding and enhanced hair strength after a few weeks to a couple of months of consistent use. For instance, one reviewer highlighted a marked improvement, stating that their hair became stronger and thicker after following a two-month treatment plan (Read Review). Similarly, another user experienced a notable decrease in hair loss after only one month of use (Read Review).
Beyond hair benefits, users also highlight improvements in their nails and overall health. For example, one reviewer mentioned that their nails ceased to break and flake, indicating a general enhancement in nail health while on the supplement (Read Review). Others reported a noticeable improvement in both hair and nail conditions, further emphasizing the comprehensive benefits of this calcium product (Read Review). While individual experiences may vary, these positive reports suggest that many users found significant relief from their hair loss concerns and other related symptoms.
Based on user reviews, many individuals have successfully combined this calcium supplement with other vitamins or supplements for positive results in managing hair loss. Users noted that the addition of vitamin D3, often included with calcium, yields beneficial effects. One reviewer specifically mentioned following their endocrinologist’s advice to take calcium citrate with D3, leading to stronger and thicker hair after a two-month regimen (Read Review). Moreover, several users expressed satisfaction with the overall health benefits they experienced, claiming improvements in hair strength and reduction of hair loss, which they attributed to this combination approach (Read Review).
Additionally, reviewers highlighted that using this supplement alongside other healthful practices contributed to their successes. For instance, one user reported remarkable results with their hair and nails after incorporating the calcium supplement into their routine during pregnancy (Read Review), indicating a consensus among users that this supplement, particularly when aligned with other care strategies, significantly aids in addressing hair loss issues. Overall, these positive user experiences suggest that combining this calcium supplement with additional vitamins could enhance its efficacy for those concerned about hair loss.
Users report that the Calcium Plus Vitamin D combination can be effective in reducing hair loss, particularly for those experiencing hair thinning after childbirth or during pregnancy. Multiple reviews highlight positive outcomes after following the recommended dosage. For instance, one user noted a significant improvement after taking calcium citrate with Vitamin D3 for two months under the advice of their endocrinologist, stating that their hair had grown stronger and thicker (Read Review). Others echoed similar sentiments, with one user mentioning a noticeable decrease in hair loss within just one month of consistent use (Read Review).
Overall, users suggest that adhering to the dosages of calcium and vitamin D as recommended by their healthcare providers led to remarkable improvements, both in hair strength and overall well-being. For example, individuals reported stronger nails, enhanced skin condition, and overall health benefits in conjunction with reduced hair loss (Read Review). While specific dosages weren't detailed in the reviews, the consistent use of calcium citrate with Vitamin D3 appears to have had a favorable impact on many users (Read Review).
Through our analysis, we found that a staggering 79.17% of these individuals were vitamin D3 deficient. The average vitamin D3 level among the patients was just 17.33 ng/ml. Most of the patients were under 30 years old, indicating that this issue may affect younger adults significantly.
Interestingly, vitamin D3 deficiency was particularly noted in various types of hair loss, including female and male pattern hair loss, diffuse alopecia areata, and telogen effluvium.
This study emphasizes the importance of recognizing and treating vitamin D3 deficiency, especially in patients experiencing diffuse hair fall. By addressing these nutritional gaps, we may offer a viable pathway to help reduce hair loss in affected individuals.
Our observations included clinical and trichoscopic evaluations at the start of treatment, after each injection, and three months following the treatment sessions. While both treatments showed a significant reduction in AA-specific trichoscopic signs, there was no statistically significant difference in the overall improvement between the two groups.
Interestingly, while both treatments were similarly effective, patients reported fewer adverse effects and greater satisfaction with the vitamin D3 injections. This points to the potential of vitamin D3 as a simpler, safer, and cost-effective option for patients dealing with patchy hair loss. Overall, our findings suggest that intralesional vitamin D3 could indeed be a promising alternative in treating alopecia areata.
Specifically, we found that 1,25-(OH)D not only extends the growth phase of hair follicles but also improves the abilities of certain skin cells that are vital for hair growth. This process relies on receptors for vitamin D, highlighting the importance of our body’s biological pathways in managing hair health.
Interestingly, our findings showed that 1,25-(OH)D can also negate some of the negative effects of DHT—a hormone often linked to hair loss. Overall, this suggests that vitamin D3 could be an effective treatment option for those experiencing androgenetic alopecia, or common hair loss.
References
- Jalil P, Masood S, Sadique M, Jalil MA, Jalil M, et al. Filling the Gaps: Vitamin D Status in Diffuse Hair Fall Among Pakistanis. Dermatol Pract Concept. 2024;14. doi:10.5826/dpc.1404a232
- Ragaie MH, Mohammed SE, Shehata SS. Intralesional vitamin D3 versus intralesional triamcinolone acetonoid in patchy alopecia areata: a comparative clinical and dermoscopic study. J Cosmet Laser Ther. 2024;26:89. doi:10.1080/14764172.2024.2389275
- Zong X, Yang S, Tang Z, Li X, Long D, et al. 1,25-(OH)D promotes hair growth by inhibiting NLRP3/IL-1β and HIF-1α/IL-1β signaling pathways. J Nutr Biochem. 2024;132:109695. doi:10.1016/j.jnutbio.2024.109695
- Meguid AMA, Ghazally A, Ahmed AM, Bakr RM. Fractional carbon dioxide laser alone and as an assisted drug delivery for treatment of alopecia areata: a clinical, dermoscopic and immunohistochemical study. Arch Dermatol Res. 2023;315:1675. doi:10.1007/s00403-023-02565-x
- Ali MS, Hafiz HSA, Ahmed NA, Galal SA. Combined microneedling with topical vitamin D3 or bimatoprost versus microneedling alone in the treatment of alopecia areata: A comparative randomized trial. J Cosmet Dermatol. 2023;22:1286. doi:10.1111/jocd.15569
- Papadimitriou DT, Bothou C, Dermitzaki E, Alexopoulos A, Mastorakos G. Treatment of alopecia totalis/universalis/focalis with vitamin D and analogs: Three case reports and a literature review. World J Clin Pediatr. 2021;10:192. doi:10.5409/wjcp.v10.i6.192
- Sattar F, Almas U, Ibrahim NA, Akhtar A, Shazad MK, et al. Efficacy of Oral Vitamin D Therapy in Patients Suffering from Diffuse Hair Loss (Telogen Effluvium). J Nutr Sci Vitaminol (Tokyo). 2021;67:68. doi:10.3177/jnsv.67.68
- Titus-Lay E, Eid TJ, Kreys TJ, Chu BXJ, Malhotra A. Trichotillomania associated with a 25-hydroxy vitamin D deficiency: A case report. Ment Health Clin. 2020;10:38. doi:10.9740/mhc.2020.01.038
- Nayak K, Garg A, Mithra P, Manjrekar P. Serum Vitamin D Levels and Diffuse Hair Fall among the Student Population in South India: A Case-Control Study. Int J Trichology. 2016;8:160. doi:10.4103/ijt.ijt_57_16
- Narang T, Daroach M, Kumaran MS. Efficacy and safety of topical calcipotriol in management of alopecia areata: A pilot study. Dermatol Ther. 2017;30. doi:10.1111/dth.12464
