Last update
5/7/2026
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9.5
USERS' SCORE
Good
Based on 2 Reviews
8.2
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol)
20 mcg(800 IU)
100%
Calcium (as Calcium Carbonate)
600 mg
46%
Magnesium (as Magnesium Oxide)
50 mg
12%
Zinc (as Zinc Oxide)
7.5 mg
68%
Copper (as Copper Oxide)
1 mg
111%
Manganese (as Manganese Sulfate)
1.8 mg
78%
Boron (as Sodium Borate)
250 mcg
**
Top Medical Research Studies
9.5
We investigated how calcium, specifically in the form of two-dimensional layered calcium disilicide nanoparticles (CSNs), can play a role in treating rheumatoid arthritis (RA). Unlike typical RA treatments that primarily focus on reducing inflammation, we observed that CSNs have multifunctional properties that can address the inflammatory aspect while also promoting bone health and repair.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
Read More
Most Useful Reviews
6
Helps with IBS
3 people found this helpful
Great value and prompt delivery! I sought a Calcium product with minimal Magnesium as I suffer from an autoimmune disorder, IBS-D. I understand that Calcium can generally slow digestion but not when combined with high levels of Magnesium. Finding pure Calcium in the UK proved challenging, so I looked online and discovered this product. I believe it has positively impacted my IBS while also enhancing my Calcium and Vitamin D levels. The delivery was swift, and the price was reasonable, prompting me to order again.
Read More
7
Improvement for mum
I regularly purchase this product for my mum, who requires more than just calcium; she also needs Vitamin D3 due to her autoimmune disorder and related bone issues. Since she started taking these supplements, there has been significant improvement in her daily life. For her age, it’s the best supplement available, and the absence of aftertaste is a major benefit.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9.5
- All Researches
9.5
We investigated how calcium, specifically in the form of two-dimensional layered calcium disilicide nanoparticles (CSNs), can play a role in treating rheumatoid arthritis (RA). Unlike typical RA treatments that primarily focus on reducing inflammation, we observed that CSNs have multifunctional properties that can address the inflammatory aspect while also promoting bone health and repair.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
6
Helps with IBS
3 people found this helpful
Great value and prompt delivery! I sought a Calcium product with minimal Magnesium as I suffer from an autoimmune disorder, IBS-D. I understand that Calcium can generally slow digestion but not when combined with high levels of Magnesium. Finding pure Calcium in the UK proved challenging, so I looked online and discovered this product. I believe it has positively impacted my IBS while also enhancing my Calcium and Vitamin D levels. The delivery was swift, and the price was reasonable, prompting me to order again.
Read More
7
Improvement for mum
I regularly purchase this product for my mum, who requires more than just calcium; she also needs Vitamin D3 due to her autoimmune disorder and related bone issues. Since she started taking these supplements, there has been significant improvement in her daily life. For her age, it’s the best supplement available, and the absence of aftertaste is a major benefit.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Ji P, Qiu S, Huang J, Wang L, Wang Y, et al. Hydrolysis of 2D Nanosheets Reverses Rheumatoid Arthritis Through Anti-Inflammation and Osteogenesis. Adv Mater. 2025;37:e2415543. 10.1002/adma.202415543
