We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
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Most Useful Reviews
9
Joint pain relief
100 people found this helpful
Thanks to this supplement, I've forgotten about bone pain and my bones no longer crunch.
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9
Bone tissue recovery
3 people found this helpful
After buying this supplement, I researched the most effective form of calcium. Despite being the cheapest, I noticed positive changes. My CT scan showed significant bone tissue recovery due to this calcium and vitamin D. I’m planning a pregnancy and may continue with this form or seek something more reliable.
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9
Effective results
1 people found this helpful
I received my calcium supplement, which I take to strengthen my bones after breaking my leg last year. It’s very effective; I noticed significant results, including improved dental health. Plus, it was delivered promptly.
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
Read More
User Reviews
USERS' SCORE
Good
Based on 32 Reviews
8.3
All Reviews
Positive Reviews
Negative Reviews
9
Joint pain relief
100 people found this helpful
Thanks to this supplement, I've forgotten about bone pain and my bones no longer crunch.
Read More
9
Bone tissue recovery
3 people found this helpful
After buying this supplement, I researched the most effective form of calcium. Despite being the cheapest, I noticed positive changes. My CT scan showed significant bone tissue recovery due to this calcium and vitamin D. I’m planning a pregnancy and may continue with this form or seek something more reliable.
Read More
9
Effective results
1 people found this helpful
I received my calcium supplement, which I take to strengthen my bones after breaking my leg last year. It’s very effective; I noticed significant results, including improved dental health. Plus, it was delivered promptly.
Read More
9
Strengthens bones
1 people found this helpful
Excellent! It aids in strengthening bones effectively.
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9
Pain relief
For over a year, my husband and I have consistently taken this calcium along with vitamin D. The cramps in my legs vanished, and my husband swiftly recovered from a fracture, alleviating his pain. Very effective and worth it!
Bone pain is a discomfort or ache that originates within the bones themselves and can range from mild to severe. It is different from muscle or joint pain, as it directly affects the skeletal structure. Bone pain can be caused by a variety of factors, including injuries, medical conditions such as osteoarthritis or osteoporosis, infections, or tumors. Symptoms may vary depending on the underlying cause but often include a dull, penetrating ache that may worsen with movement or pressure.
If you're experiencing persistent bone pain, it’s essential to consult with a healthcare professional for a proper diagnosis and treatment plan. Imaging tests like X-rays, MRI, or CT scans may be utilized to determine the root cause of the pain. Treatment can vary widely, ranging from medications to alleviate pain and inflammation to physical therapy or, in some cases, surgical interventions. Understanding the underlying cause is crucial to effectively managing bone pain and ensuring the best path to recovery.
Calcium is a chemical element represented by the symbol Ca and atomic number 20. It is an essential mineral in the body, playing a critical role in various physiological processes. As one of the most abundant elements in nature, calcium is particularly vital for maintaining strong bones and teeth, where about 99% of the body's calcium is stored. Beyond its structural function, calcium is crucial in muscle contraction, blood clotting, and nerve transmission, making it a key player in overall health.
Dietary sources of calcium include dairy products such as milk, yogurt, and cheese, as well as leafy green vegetables, nuts, seeds, and fortified foods. The recommended daily intake of calcium varies by age and sex, but generally, adults should aim for approximately 1,000 mg per day. For those who may struggle to meet their needs through diet alone, calcium supplements are available but should be taken with caution. It's essential to consult with a healthcare provider before starting any supplement regimen to avoid potential side effects or interactions with medications.
Calcium is an essential mineral that plays a critical role in maintaining bone health and strength. Adequate calcium intake is crucial for the prevention of various bone-related issues, including osteopenia and osteoporosis, conditions that can lead to increased bone pain and fractures. When the body does not receive enough calcium, it may start to leach this mineral from the bones, potentially leading to weakness and pain. Therefore, ensuring you meet your daily calcium requirements can contribute to healthier bones and may, in turn, help alleviate some types of bone pain associated with deficiencies.
However, it's essential to note that while calcium is fundamental for bone health, it may not directly relieve bone pain caused by other factors such as injury, arthritis, or other medical conditions. For those experiencing chronic bone pain, incorporating calcium-rich foods into your diet—such as dairy products, leafy greens, and fortified foods—should be part of a broader approach that includes medical evaluation and potential treatment options. Consulting a healthcare professional is advised to determine the underlying causes of bone pain and to develop a comprehensive plan that may include dietary adjustments, exercise, and medications if necessary.
Based on user reviews, the timeline for seeing results from this bone pain supplement can vary. Many users report noticeable improvements within a few months of consistent use. For example, one user mentioned that after three months of taking the supplement, their bone pain began to subside gradually Read Review. Another user experienced significant results, including improved dental health, after starting their regimen with a consistent intake Read Review.
In addition, some individuals, while not specifying an exact timeframe, highlight long-term positive effects, suggesting that ongoing use leads to cumulative results, such as alleviated pain and restored bone health Read Review. Overall, users affirm that while some may notice improvements sooner, a consistent regimen over several weeks to months is advisable for optimal results.
This supplement has mixed support from scientific research regarding its efficacy for bone pain. A study investigated the connection between intravenous iron infusions and bone pain, specifically focusing on patients diagnosed with osteomalacia who underwent supportive treatment that included calcium, phosphate, and active Vitamin D supplementation. While this treatment regimen did show improvements in biochemical markers and reduced pain scores, the study highlighted that it was challenging to isolate the specific effects of calcium on bone pain from the other supportive therapies used ([1]).
Consequently, while calcium is included in treatment protocols aimed at addressing bone pain, its direct impact remains unclear due to the multifaceted nature of the interventions. Overall, while there is a suggestion that calcium may contribute to alleviating bone pain in certain contexts, more targeted studies are needed to confirm its effectiveness as a standalone supplement for this issue.
Users report a variety of improvements in their symptoms after taking this calcium supplement, with many noting significant relief from bone pain and enhanced bone strength. For instance, one user mentioned that their bone pain almost vanished after five years of discomfort, crediting this supplement for the transformation Read Review. Another user highlighted that after consistently taking the supplement, both they and their spouse experienced a marked improvement; their leg cramps disappeared, and their husband quickly recovered from a fracture Read Review.
Moreover, several reviews indicate enhanced overall well-being linked to the supplement, with users experiencing benefits such as increased energy levels, improved dental health, and a noticeable boost in bone density Read Review. Despite the variability in individual experiences and occasional side effects like nausea noted by some Read Review; the general consensus leans positively towards this product's effectiveness in improving bone health and reducing discomfort.
Based on user reviews, many individuals have found considerable success in combining this calcium supplement with other nutrients such as vitamin D and collagen to enhance their bone health and alleviate pain. For instance, one user highlighted the effectiveness of taking the supplement with vitamin D, which resulted in reduced leg cramps and accelerated recovery from a fracture for both themselves and their spouse Read Review. Another user specifically stated that mixing this calcium supplement with collagen helped in stopping bone fractures after experiencing a broken arm Read Review.
Moreover, several reviews emphasize the importance of consistent intake of this supplement alongside other vitamins to achieve optimal results. One user reported improved symptoms and maintained a regimen that included additional calcium in their multivitamins after realizing it was lacking, thus improving their overall condition Read Review. These anecdotes suggest that users are successfully leveraging combinations of supplements to effectively manage bone pain and improve general bone health, indicating that stacking may enhance the benefits of this calcium product.
Based on user reviews, many consumers noted the effectiveness of calcium supplements for alleviating bone pain, with some consistently using them for improved bone health. For instance, one user reported significant decreases in their knee pain after five years of discomfort, attributing the relief to their calcium supplement regimen, although they also noted that it occasionally caused nausea (Read Review). In another review, a user mentioned following their doctor's advice to take 600mg of calcium daily, which led to a slight improvement in their condition after three months of usage (Read Review).
Satisfaction levels were high among users who consistently took calcium supplements in conjunction with vitamin D, leading to improvements in their overall health, including the cessation of leg cramps and better recovery post-fracture (Read Review). Ultimately, users recommend maintaining a steady calcium intake, particularly for those over 35, as part of a proactive approach to support bone strength and mitigate pain over time (Read Review).
7.5
Gradual relief
1 people found this helpful
It is beneficial with continued use; I noticed my bone pain subsiding gradually after three months. Just ensure to evaluate before using it.
9
Effective results
1 people found this helpful
I received my calcium supplement, which I take to strengthen my bones after breaking my leg last year. It’s very effective; I noticed significant results, including improved dental health. Plus, it was delivered promptly.
8
Brittle nails treatment
9 people found this helpful
This supplement has relieved my bone pain and improved my nails, as I suffered from vitamin D and calcium deficiency due to limited sun exposure and dislike for dairy. Taking this vitamin consistently made a noticeable difference. I recommend taking it at night to help with sleep.
9
Knee pain relief
4 people found this helpful
Thank you, Ayherb! I've taken this calcium supplement for the second time and my knee pain has nearly vanished. After five years of discomfort and trying everything else, this product has worked wonders. Although it occasionally makes me feel nauseous, I'm optimistic and have ordered a second jar. I hope it helps others too!
9
Pain relief
For over a year, my husband and I have consistently taken this calcium along with vitamin D. The cramps in my legs vanished, and my husband swiftly recovered from a fracture, alleviating his pain. Very effective and worth it!
9
Prevents fractures
A great supplement that I usually mix with collagen. I can honestly say it has really helped stop my bones from breaking. After a broken arm, I’ve been continuously taking it for about two years. If you're over 35, it’s time to start for better health in older age. Thank you!
7.5
Condition improvement
1 people found this helpful
I have a condition that causes body pain without calcium, so I quickly purchased this product after realising my multivitamin was lacking it. Taking this supplement improved my symptoms.
7.5
Slight improvement
2 people found this helpful
I purchased this as my doctor advised me to take 600mg of calcium daily due to signs of osteoporosis in my bone density test. The tablets are large, so I cut them in half for easier consumption. After three months of taking this supplement, my re-examination showed a slight improvement in my condition.
8
Calcium's role in bone pain unclear
In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution.
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
References
von Brackel FN, Grambeck J, Barvencik F, Amling M, Oheim R. In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution. JBMR Plus. 2024;8:ziae139. 10.1093/jbmrpl/ziae139