Last update
5/21/2026
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.5
USERS' SCORE
Good
Based on 1 Review
8.4
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Calcium (as Calcium Carbonate)
600 mg
46%
Top Medical Research Studies
9
We explored how calcium phosphate (CaP) injections impact knee pain, particularly in patients suffering from osteoarthritis-related bone marrow lesions (OA-BML). In this study, we compared two groups of patients: those who received knee arthroscopy combined with CaP injections and those who had knee arthroscopy for different knee issues.
Our observations showed that patients receiving the CaP injections experienced less frequent conversions to total knee arthroplasty (TKA) when compared to the other group. Notably, within the CaP group, we noticed a significant improvement in their knee injury and functional outcome scores before and after the procedure. However, patients who only underwent knee arthroscopy did not show the same level of improvement.
Overall, we found that adding CaP injections during knee surgery for OA-BML significantly enhanced functional outcomes over traditional surgery alone. This study underscores the potential benefits of CaP treatments in managing knee pain and improving quality of life for those suffering from knee OA.
Our observations showed that patients receiving the CaP injections experienced less frequent conversions to total knee arthroplasty (TKA) when compared to the other group. Notably, within the CaP group, we noticed a significant improvement in their knee injury and functional outcome scores before and after the procedure. However, patients who only underwent knee arthroscopy did not show the same level of improvement.
Overall, we found that adding CaP injections during knee surgery for OA-BML significantly enhanced functional outcomes over traditional surgery alone. This study underscores the potential benefits of CaP treatments in managing knee pain and improving quality of life for those suffering from knee OA.
Read More
4
We explored the role of calcium gluconate as an activator alongside platelet-rich plasma (PRP) injections for patients dealing with early knee osteoarthritis. In this study, participants were split into two groups: one received PRP alone, while the other got PRP mixed with calcium gluconate.
Both groups were evaluated over six months for pain relief and overall satisfaction. Interestingly, despite a noticeable decrease in pain and improvement in overall function in both groups, we found no significant differences when comparing the effectiveness of the two treatments.
This led us to conclude that adding calcium gluconate might not provide any extra benefit to PRP injections in managing knee pain for early-stage osteoarthritis, which is quite important for patients considering their treatment options.
Both groups were evaluated over six months for pain relief and overall satisfaction. Interestingly, despite a noticeable decrease in pain and improvement in overall function in both groups, we found no significant differences when comparing the effectiveness of the two treatments.
This led us to conclude that adding calcium gluconate might not provide any extra benefit to PRP injections in managing knee pain for early-stage osteoarthritis, which is quite important for patients considering their treatment options.
Read More
Most Useful Reviews
7.5
Less knee pain
My knees hurt, but since starting Calcemin, they have been less painful and crunching less. I take it with vitamin K. I recommend it.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.5
- All Researches
9
We explored how calcium phosphate (CaP) injections impact knee pain, particularly in patients suffering from osteoarthritis-related bone marrow lesions (OA-BML). In this study, we compared two groups of patients: those who received knee arthroscopy combined with CaP injections and those who had knee arthroscopy for different knee issues.
Our observations showed that patients receiving the CaP injections experienced less frequent conversions to total knee arthroplasty (TKA) when compared to the other group. Notably, within the CaP group, we noticed a significant improvement in their knee injury and functional outcome scores before and after the procedure. However, patients who only underwent knee arthroscopy did not show the same level of improvement.
Overall, we found that adding CaP injections during knee surgery for OA-BML significantly enhanced functional outcomes over traditional surgery alone. This study underscores the potential benefits of CaP treatments in managing knee pain and improving quality of life for those suffering from knee OA.
Our observations showed that patients receiving the CaP injections experienced less frequent conversions to total knee arthroplasty (TKA) when compared to the other group. Notably, within the CaP group, we noticed a significant improvement in their knee injury and functional outcome scores before and after the procedure. However, patients who only underwent knee arthroscopy did not show the same level of improvement.
Overall, we found that adding CaP injections during knee surgery for OA-BML significantly enhanced functional outcomes over traditional surgery alone. This study underscores the potential benefits of CaP treatments in managing knee pain and improving quality of life for those suffering from knee OA.
Read More
4
We explored the role of calcium gluconate as an activator alongside platelet-rich plasma (PRP) injections for patients dealing with early knee osteoarthritis. In this study, participants were split into two groups: one received PRP alone, while the other got PRP mixed with calcium gluconate.
Both groups were evaluated over six months for pain relief and overall satisfaction. Interestingly, despite a noticeable decrease in pain and improvement in overall function in both groups, we found no significant differences when comparing the effectiveness of the two treatments.
This led us to conclude that adding calcium gluconate might not provide any extra benefit to PRP injections in managing knee pain for early-stage osteoarthritis, which is quite important for patients considering their treatment options.
Both groups were evaluated over six months for pain relief and overall satisfaction. Interestingly, despite a noticeable decrease in pain and improvement in overall function in both groups, we found no significant differences when comparing the effectiveness of the two treatments.
This led us to conclude that adding calcium gluconate might not provide any extra benefit to PRP injections in managing knee pain for early-stage osteoarthritis, which is quite important for patients considering their treatment options.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Less knee pain
My knees hurt, but since starting Calcemin, they have been less painful and crunching less. I take it with vitamin K. I recommend it.
Read More
Frequently Asked Questions
7.5
Less knee pain
My knees hurt, but since starting Calcemin, they have been less painful and crunching less. I take it with vitamin K. I recommend it.
4
We explored the role of calcium gluconate as an activator alongside platelet-rich plasma (PRP) injections for patients dealing with early knee osteoarthritis. In this study, participants were split into two groups: one received PRP alone, while the other got PRP mixed with calcium gluconate.
Both groups were evaluated over six months for pain relief and overall satisfaction. Interestingly, despite a noticeable decrease in pain and improvement in overall function in both groups, we found no significant differences when comparing the effectiveness of the two treatments.
This led us to conclude that adding calcium gluconate might not provide any extra benefit to PRP injections in managing knee pain for early-stage osteoarthritis, which is quite important for patients considering their treatment options.
Both groups were evaluated over six months for pain relief and overall satisfaction. Interestingly, despite a noticeable decrease in pain and improvement in overall function in both groups, we found no significant differences when comparing the effectiveness of the two treatments.
This led us to conclude that adding calcium gluconate might not provide any extra benefit to PRP injections in managing knee pain for early-stage osteoarthritis, which is quite important for patients considering their treatment options.
9
We explored how calcium phosphate (CaP) injections impact knee pain, particularly in patients suffering from osteoarthritis-related bone marrow lesions (OA-BML). In this study, we compared two groups of patients: those who received knee arthroscopy combined with CaP injections and those who had knee arthroscopy for different knee issues.
Our observations showed that patients receiving the CaP injections experienced less frequent conversions to total knee arthroplasty (TKA) when compared to the other group. Notably, within the CaP group, we noticed a significant improvement in their knee injury and functional outcome scores before and after the procedure. However, patients who only underwent knee arthroscopy did not show the same level of improvement.
Overall, we found that adding CaP injections during knee surgery for OA-BML significantly enhanced functional outcomes over traditional surgery alone. This study underscores the potential benefits of CaP treatments in managing knee pain and improving quality of life for those suffering from knee OA.
Our observations showed that patients receiving the CaP injections experienced less frequent conversions to total knee arthroplasty (TKA) when compared to the other group. Notably, within the CaP group, we noticed a significant improvement in their knee injury and functional outcome scores before and after the procedure. However, patients who only underwent knee arthroscopy did not show the same level of improvement.
Overall, we found that adding CaP injections during knee surgery for OA-BML significantly enhanced functional outcomes over traditional surgery alone. This study underscores the potential benefits of CaP treatments in managing knee pain and improving quality of life for those suffering from knee OA.
References
- Rai S, Patel S, Chouhan DK, Jain A, Thami T, et al. Is There a Need for an Exogenous Activator Along with PRP for Early Knee Osteoarthritis? A Triple-Blinded Randomized Control Trial. Indian J Orthop. 2024;58:905. 10.1007/s43465-024-01159-7
- Stratton A, Wanless M, Abidi N. Total Knee Conversion Rates and Functional Outcome After Calcium Phosphate Injection for Bone Marrow Lesions of the Knee. J Knee Surg. 2024;37:341. 10.1055/a-2094-5724
