'
21st Century Zinc Chewable
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
USERS' SCORE
Excellent
Based on 142 Reviews
9.1
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Total Carbohydrate
<1 g
<1%‡
Vitamin C (as Ascorbic Acid & Sodium Ascorbate)
60 mg
67%
Vitamin B-6 (as Pyridoxine HCl)
5 mg
294%
Zinc (as Zinc Aspartate)
15 mg
136%

Top Medical Research Studies

8
Zinc’s effects on colds
Zinc for prevention and treatment of the common cold: Summary of a Cochrane review.
High relevance to cold treatment
We explored how zinc might help in treating and preventing the common cold. The study focused on zinc's effects, isolating it from other treatments to understand its true impact on cold symptoms. By doing this, the researchers aimed to clarify whether zinc could genuinely shorten the duration of a cold or alleviate its symptoms.

The findings were intriguing but showed that zinc might not yield significant benefits for everyone. While some individuals reported a slight reduction in cold symptoms, the evidence did not strongly support zinc as an effective treatment overall.

This means that, for those seeking relief from a nasty cold, zinc alone might not be the go-to solution we hoped it would be. It’s essential to consider this information when deciding on a cold treatment plan and to approach zinc with realistic expectations.
Read More
7
Effectiveness of Vitamin C on Colds
Vitamin C for the common cold and pneumonia.
Strong relevance to cold prevention
We explored the effects of vitamin C on the common cold and pneumonia by examining a range of studies. Interestingly, research on animals suggests that vitamin C may have protective effects against infections. However, when it comes to preventing colds in the general population, taking more than 1 gram of vitamin C per day didn’t show significant benefits.

But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.

Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.

Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
Read More
9
Vitamin C improves cold tolerance
Application of Exogenous Ascorbic Acid Enhances Cold Tolerance in Tomato Seedlings through Molecular and Physiological Responses.
Directly addresses cold tolerance
We explored the effects of ascorbic acid, commonly known as vitamin C, on cold tolerance in tomato seedlings. In our study, we discovered that applying vitamin C significantly boosts the seedlings' ability to handle cold stress.

By enhancing the antioxidant defense system, vitamin C treatment increased the enzyme activity in the seedlings' leaves. Additionally, it raised levels of important compounds such as proline, sugar, and abscisic acid, all of which play crucial roles in plant stress responses.

Our observations showed that vitamin C also protects the photosynthesis system of tomato seedlings. This implies that it helps maintain chlorophyll function, which is critical for the plant's overall health, especially under cold conditions.

Moreover, we found that vitamin C treatments led to increased expression of genes linked to antioxidant enzymes and cold response mechanisms. Overall, our findings suggest that exogenous vitamin C is a beneficial approach to improve cold tolerance in tomatoes and may provide helpful insights for farmers looking to cultivate hardier varieties during colder months.
Read More

Most Useful Reviews

9.5
Effective for colds
The firm is reliable, I trust it. This complex effectively copes with colds and acute respiratory infections. As soon as the illness begins, I dissolve 1-2 tablets 3-4 times a day. The taste has a slight sourness. It helps me recover in 3-4 days.
Read More
9.5
Godsend for colds
This complex is just brilliant! It deals wonderfully with colds. When my cough starts, I dissolve 1 tablet 2-4 times a day. The taste is pleasant, with a slight sour cherry. It helps me feel better in 2-3 days. Just remember to start taking it promptly. Wishing you health!
Read More
8.8
Prevents colds
This is great for preventing ARVI and supporting the immune system. When I feel it coming on, I take it immediately. It effectively prevents ARVI, colds, and helps me avoid getting ill. The tablets taste nice, but take them with food to avoid nausea on an empty stomach. I recommend it!
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
  • All Researches
9
Zinc enhances rice cold resistance
Effects of different cold-resistant agents and application methods on yield and cold-resistance of machine-transplanted early rice.
Study highlights zinc's effectiveness
We explored the impact of zinc-amino acids chelate on cold stress resistance in machine-transplanted early rice. Our investigation included other cold-resistant agents like uniconazole and abscisic acid, but we found zinc to be particularly effective. When applied during the regreening stage, zinc notably enhanced rice growth by promoting tillering and increasing the leaf area, which led to better yields.

We noted that zinc-amino acids chelate improved antioxidant enzyme activities, which are crucial for helping rice withstand cold temperatures. The yield of rice treated with zinc was approximately 9.22% higher than with uniconazole and 7.14% higher than with abscisic acid.

Additionally, we observed that using 750 g/ha of zinc-amino acids chelate during the transplanting and regreening stages yielded the best results. The timing of the application played a critical role, as spraying during these specific phases maximized both yield and cold resistance.

Overall, zinc treatments stand out as a promising option for improving cold stress resilience in early rice, making it a key consideration for farmers dealing with cold climate conditions.
Read More
9
Vitamin C improves cold tolerance
Application of Exogenous Ascorbic Acid Enhances Cold Tolerance in Tomato Seedlings through Molecular and Physiological Responses.
Directly addresses cold tolerance
We explored the effects of ascorbic acid, commonly known as vitamin C, on cold tolerance in tomato seedlings. In our study, we discovered that applying vitamin C significantly boosts the seedlings' ability to handle cold stress.

By enhancing the antioxidant defense system, vitamin C treatment increased the enzyme activity in the seedlings' leaves. Additionally, it raised levels of important compounds such as proline, sugar, and abscisic acid, all of which play crucial roles in plant stress responses.

Our observations showed that vitamin C also protects the photosynthesis system of tomato seedlings. This implies that it helps maintain chlorophyll function, which is critical for the plant's overall health, especially under cold conditions.

Moreover, we found that vitamin C treatments led to increased expression of genes linked to antioxidant enzymes and cold response mechanisms. Overall, our findings suggest that exogenous vitamin C is a beneficial approach to improve cold tolerance in tomatoes and may provide helpful insights for farmers looking to cultivate hardier varieties during colder months.
Read More
8
Zinc mouthwash reduces cold symptoms
Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms.
Focus on combined treatment effects
We explored the impact of regular gargling with an antimicrobial mouthwash that contains both cetylpyridinium chloride and zinc on upper respiratory symptoms. A total of 150 participants were split into two groups; one group just brushed their teeth, while the other group brushed and gargled with the mouthwash twice a day over three months.

Our findings revealed that those using the mouthwash experienced a 21.5% reduction in the frequency and an 11% decrease in the severity of respiratory symptoms. This strongly suggests that incorporating zinc, alongside cetylpyridinium chloride, can provide benefits for those suffering from cold-related symptoms.

However, it’s important to note that this study’s design involved multiple components, and we can’t isolate zinc’s effectiveness from the impact of the other ingredients. Still, the results encourage us to view mouthwash with these ingredients as a helpful addition to our daily hygiene routines, especially during cold and flu season.

Ultimately, this research indicates that gargling with a mouthwash containing zinc and cetylpyridinium chloride can indeed help alleviate some unpleasant cold symptoms, but we should be mindful of the combination's effects when interpreting these outcomes.
Read More
8
Zinc’s effects on colds
Zinc for prevention and treatment of the common cold: Summary of a Cochrane review.
High relevance to cold treatment
We explored how zinc might help in treating and preventing the common cold. The study focused on zinc's effects, isolating it from other treatments to understand its true impact on cold symptoms. By doing this, the researchers aimed to clarify whether zinc could genuinely shorten the duration of a cold or alleviate its symptoms.

The findings were intriguing but showed that zinc might not yield significant benefits for everyone. While some individuals reported a slight reduction in cold symptoms, the evidence did not strongly support zinc as an effective treatment overall.

This means that, for those seeking relief from a nasty cold, zinc alone might not be the go-to solution we hoped it would be. It’s essential to consider this information when deciding on a cold treatment plan and to approach zinc with realistic expectations.
Read More
7
Effectiveness of Vitamin C on Colds
Vitamin C for the common cold and pneumonia.
Strong relevance to cold prevention
We explored the effects of vitamin C on the common cold and pneumonia by examining a range of studies. Interestingly, research on animals suggests that vitamin C may have protective effects against infections. However, when it comes to preventing colds in the general population, taking more than 1 gram of vitamin C per day didn’t show significant benefits.

But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.

Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.

Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
Read More

User Reviews

USERS' SCORE
Excellent
Based on 142 Reviews
9.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Effective for colds
The firm is reliable, I trust it. This complex effectively copes with colds and acute respiratory infections. As soon as the illness begins, I dissolve 1-2 tablets 3-4 times a day. The taste has a slight sourness. It helps me recover in 3-4 days.
9.5
Godsend for colds
This complex is just brilliant! It deals wonderfully with colds. When my cough starts, I dissolve 1 tablet 2-4 times a day. The taste is pleasant, with a slight sour cherry. It helps me feel better in 2-3 days. Just remember to start taking it promptly. Wishing you health!
8.8
Prevents colds
This is great for preventing ARVI and supporting the immune system. When I feel it coming on, I take it immediately. It effectively prevents ARVI, colds, and helps me avoid getting ill. The tablets taste nice, but take them with food to avoid nausea on an empty stomach. I recommend it!
Read More
9.5
Magic pill
Beautiful! In the cold season, I give half a tablet to dissolve for my child and a whole to adults. At the first sign of a cold, I administer it for five days. I can’t imagine what I would do without this magic pill. I'm very grateful.
9.5
Effective remedy
These tablets are delicious with a slight sourness. They genuinely work if taken at the onset of a cold, helping one to either avoid getting sick or recover more swiftly.
image