Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Good
Based on 9 Reviews
8
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Thiamin (as Thiamin Mononitrate, Vitamin B-1)
100 mg
8,333%
Riboflavin (Vitamin B-2) 
100 mg
7,692%
Niacin (as Niacinamide)
100 mg
625%
Vitamin B-6 (as Pyridoxine HCl)
100 mg
5,882%
Folate
667 mcg DFE(400 mcg Folic Acid
167%
Vitamin B-12 (as Cyanocobalamin)
100 mcg
4,167%
Biotin
100 mcg
333%
Pantothenic Acid (as d-Calcium Pantothenate)
100 mg
2,000%
Calcium (as Calcium Carbonate & Dicalcium Phosphate)
124 mg
10%

Top Medical Research Studies

We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
Read More
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.

After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.

Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
Read More
8
Nicotinamide suppresses autoimmune activation
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.

Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Read More

Most Useful Reviews

9
Real help
25 people found this helpful
This is the BEST HELP for the neurotic! Having struggled with depression and anxiety-depressive disorder for a decade, I felt an overwhelming sense of calm after taking this pill. It transformed my life almost immediately, alleviating fears that had tormented me. After consuming it for two months and now on a break, I am grateful for this discovery, which I wish I had known about sooner. It truly provides real help. I recommend it to everyone!
Read More
7.5
Positive improvement
155 people found this helpful
I ordered this complex for a test, and after two weeks of taking it, I noticed an effect. I continue taking the drug in hopes of even greater benefits.
Read More
7.5
Increased calmness
5 people found this helpful
I was advised to take vitamins at a dose of 100 IU per day by my endocrinologist. Skeptical at first, I was pleasantly surprised when, after just a week, I felt significantly calmer. My reactions to stress improved, sleep quality enhanced, and my hair began to shine. I can't imagine life without these vitamins and will definitely order more.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
  • All Researches
9
Biotin deficiency mimics neurological disorders
We explored three cases of biotinidase deficiency (BTD) that were misdiagnosed as neuromyelitis optica spectrum disorder (NMOSD) due to similar symptoms and neuroimaging results. Initially, two patients responded to immune therapy but later relapsed, while one showed no improvement. Interestingly, after timely diagnosis and biotin supplementation, two patients exhibited remarkable recoveries in both motor function and vision. This highlights the critical need for accurate diagnosis, as early treatment of BTD can lead to significant improvements.
Read More
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.

After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.

Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
Read More
We focused on a case of pernicious anemia in a 51-year-old Ugandan man who presented with recurring lower limb weakness. After initial treatment for vitamin B12 deficiency years ago and further testing, we confirmed his diagnosis of pernicious anemia marked by low cobalamin levels. Thanks to timely parenteral methylcobalamin therapy, he showed improvement. This case underscores the importance of recognizing vitamin B12 deficiency, especially in rural and resource-limited settings, to address neurological symptoms quickly.
Read More
8
Nicotinamide suppresses autoimmune activation
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.

Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
Read More
7
Vitamin B may indicate GBS severity
We aimed to see if vitamin B levels could signal the severity of Guillain-Barré syndrome (GBS) and its potential for complications like respiratory failure. Our study involved 50 GBS patients, where we examined their vitamin B and creatine kinase levels alongside their motor abilities.

Interestingly, we found that 44% of patients had low vitamin B levels, which linked strongly to GBS severity. However, while vitamin B showed predictive value, the creatine kinase levels did not relate to GBS severity.
Read More

User Reviews

USERS' SCORE
Good
Based on 9 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Real help
25 people found this helpful
This is the BEST HELP for the neurotic! Having struggled with depression and anxiety-depressive disorder for a decade, I felt an overwhelming sense of calm after taking this pill. It transformed my life almost immediately, alleviating fears that had tormented me. After consuming it for two months and now on a break, I am grateful for this discovery, which I wish I had known about sooner. It truly provides real help. I recommend it to everyone!
Read More
7.5
Positive improvement
155 people found this helpful
I ordered this complex for a test, and after two weeks of taking it, I noticed an effect. I continue taking the drug in hopes of even greater benefits.
Read More
7.5
Increased calmness
5 people found this helpful
I was advised to take vitamins at a dose of 100 IU per day by my endocrinologist. Skeptical at first, I was pleasantly surprised when, after just a week, I felt significantly calmer. My reactions to stress improved, sleep quality enhanced, and my hair began to shine. I can't imagine life without these vitamins and will definitely order more.
Read More
9
Enhanced calmness
3 people found this helpful
It truly works! Prescribed by my endocrinologist at 100 IU daily, I was initially sceptical, but just a week in, I felt calmer and noticed improved sleeping patterns along with shinier hair. I will undoubtedly order more. Highly recommend!
Read More
9
Energising boost
1 people found this helpful
I tried this for the first time and felt a surge of energy within a week. My stress resistance improved, and fatigue diminished by the end of the working day. Additionally, two small wen on my forehead reduced in size and dried up after a month. I am satisfied and plan to order more in the future. Highly recommend!
Read More

Frequently Asked Questions

7.5
Increased calmness
5 people found this helpful
I was advised to take vitamins at a dose of 100 IU per day by my endocrinologist. Skeptical at first, I was pleasantly surprised when, after just a week, I felt significantly calmer. My reactions to stress improved, sleep quality enhanced, and my hair began to shine. I can't imagine life without these vitamins and will definitely order more.
9
Energising boost
1 people found this helpful
I tried this for the first time and felt a surge of energy within a week. My stress resistance improved, and fatigue diminished by the end of the working day. Additionally, two small wen on my forehead reduced in size and dried up after a month. I am satisfied and plan to order more in the future. Highly recommend!
7.5
Positive improvement
155 people found this helpful
I ordered this complex for a test, and after two weeks of taking it, I noticed an effect. I continue taking the drug in hopes of even greater benefits.
9
Real help
25 people found this helpful
This is the BEST HELP for the neurotic! Having struggled with depression and anxiety-depressive disorder for a decade, I felt an overwhelming sense of calm after taking this pill. It transformed my life almost immediately, alleviating fears that had tormented me. After consuming it for two months and now on a break, I am grateful for this discovery, which I wish I had known about sooner. It truly provides real help. I recommend it to everyone!
9
Enhanced calmness
3 people found this helpful
It truly works! Prescribed by my endocrinologist at 100 IU daily, I was initially sceptical, but just a week in, I felt calmer and noticed improved sleeping patterns along with shinier hair. I will undoubtedly order more. Highly recommend!
2
Digestive issues
15 people found this helpful
I started taking this drug as per my hematologist's recommendation for my multifactorial anemia. While my skin condition improved after a week, I experienced severe nausea, bloating, and diarrhoea. Once I stopped the drug, all symptoms disappeared within three days. Unfortunately, I won’t take it again due to these side effects, even though there were no adverse reactions from the domestic drug.
7.5
Effective results
1 people found this helpful
I was pleased with this complex, which supports my osteochondrosis. It was costly to keep buying vitamin B treatments elsewhere. After taking this one, I felt a noticeable improvement. I had less neck pain, and the biotin content is a bonus. I have ordered this complex along with another one containing zinc and am satisfied with both.
8
Pernicious anemia misdiagnosed as fibromyalgia
We explored a notable case of a woman suffering from pernicious anemia, an autoimmune condition that can be misdiagnosed due to its vague symptoms like fatigue and cognitive issues.

After years of struggling with these nonspecific symptoms, her low vitamin B12 levels were finally identified as the underlying cause.

Upon receiving treatment with vitamin B12, she experienced neurological improvements, highlighting the importance of recognizing this deficiency, even when traditional anemia indicators are absent.
8
Nicotinamide suppresses autoimmune activation
We explored the influence of Nicotinamide (NAM), a form of vitamin B3, on dendritic cells (DCs) in autoimmune diseases. Our research indicates that NAM can effectively reduce the overactivation of DCs, helping to ease symptoms in conditions like psoriasis.

Through detailed analysis of available studies, we found that NAM affects DCs via a specific signaling pathway, ultimately offering a potential new direction for treatment. Importantly, these findings highlight NAM’s significant role in managing autoimmune disorders related to immune response regulation.
7
Vitamin B may indicate GBS severity
We aimed to see if vitamin B levels could signal the severity of Guillain-Barré syndrome (GBS) and its potential for complications like respiratory failure. Our study involved 50 GBS patients, where we examined their vitamin B and creatine kinase levels alongside their motor abilities.

Interestingly, we found that 44% of patients had low vitamin B levels, which linked strongly to GBS severity. However, while vitamin B showed predictive value, the creatine kinase levels did not relate to GBS severity.

References

  1. Jatav VS, Sardana V, Bhushan B, Maheshwari D, Garg S, et al. Correlation of Serum Vitamin B and Muscle Enzyme (CK-NAC) Level with Severity of Guillain-Barre Syndrome and Its Prediction in Respiratory Failure. J Assoc Physicians India. 2025;73:48. 10.59556/japi.73.0892
  2. Mesgarankarimi A, Rezapour M, Tabrizi N. A long-standing undiagnosed case of vitamin B12 deficiency: a case report. J Med Case Rep. 2025;19:151. 10.1186/s13256-025-05149-7
  3. Mswelo VE, David MM, Banturaki A, Munyambalu DK, Hassan HA, et al. Rural health challenges in Western Uganda: pernicious anemia masquerading as recurrent lower limb weakness-a case report. J Med Case Rep. 2025;19:60. 10.1186/s13256-025-05095-4
  4. Cao AP, Wang YY, Shen YY, Liu YH, Liu JY, et al. Nicotinamide Suppresses Hyperactivation of Dendritic Cells to Control Autoimmune Disease through PARP Dependent Signaling. Nutrients. 2024;16. 10.3390/nu16162665
  5. Ali F, Mukhtiar K, Raza M, Ibrahim S. Atypical presentation of biotinidase deficiency: masquerading neuromyelitis optica spectrum disorder. BMJ Case Rep. 2024;17. 10.1136/bcr-2023-258703
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