Last update
4/14/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 12 Reviews
8.1
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Thiamin (as Thiamin Mononitrate, Vitamin B-1)
100 mg
8,333%
Riboflavin (Vitamin B-2)
100 mg
7,692%
Niacin (as Niacinamide)
100 mg
625%
Vitamin B-6 (as Pyridoxine HCl)
100 mg
5,882%
Folate
667 mcg DFE(400 mcg Folic Acid
167%
Vitamin B-12 (as Cyanocobalamin)
100 mcg
4,167%
Biotin
100 mcg
333%
Pantothenic Acid (as d-Calcium Pantothenate)
100 mg
2,000%
Calcium (as Calcium Carbonate & Dicalcium Phosphate)
124 mg
10%
Top Medical Research Studies
7
We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
Read More
Most Useful Reviews
9
Significant improvement noted
2 people found this helpful
I started taking the Vital B Complete Complex as I was perpetually exhausted and needed an energy boost. After just one week, I felt significantly more alert and less fatigued. My mood has stabilised, likely thanks to the B vitamins supporting my nervous system.
Read More
9
Highly effective remedy
1 people found this helpful
Excellent for Chronic Fatigue Syndrome! 👍👍👍👍
Read More
8
Eliminates fatigue
1 people found this helpful
I consider these daily supplements essential. Vitamin B makes a notable difference in my daily life. I feel it significantly helps in eliminating fatigue, as I can clearly tell when I am taking it versus when I am not. It is highly recommended!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
- All Researches
7
We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
Read More
User Reviews
USERS' SCORE
Good
Based on 12 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Significant improvement noted
2 people found this helpful
I started taking the Vital B Complete Complex as I was perpetually exhausted and needed an energy boost. After just one week, I felt significantly more alert and less fatigued. My mood has stabilised, likely thanks to the B vitamins supporting my nervous system.
Read More
9
Highly effective remedy
1 people found this helpful
Excellent for Chronic Fatigue Syndrome! 👍👍👍👍
Read More
8
Eliminates fatigue
1 people found this helpful
I consider these daily supplements essential. Vitamin B makes a notable difference in my daily life. I feel it significantly helps in eliminating fatigue, as I can clearly tell when I am taking it versus when I am not. It is highly recommended!
Read More
7.5
Increased energy levels
The complex of B vitamins positively impacts the nervous system, strengthening it and providing energy while alleviating fatigue. It especially aids in managing Chronic Fatigue Syndrome and supports the nervous system effectively. I feel more energetic, and my metabolism has sped up. I hope to enhance my stress resistance and increase my energy further. The quality is good, with a neutral taste and an unusual aroma. The strength and effect are remarkable, and I am pleased with the results.
Read More
7.5
Productivity increased
2 people found this helpful
One notable benefit is a significant increase in my energy levels. Taking the complex in the morning helps, and I feel more alert and active throughout the day. I noticed a marked improvement in my productivity; the fatigue episodes have diminished. B vitamins have evidently supported my nervous system, helping me react more calmly to stress, leading to a more stable mood.
Read More
Frequently Asked Questions
9
Significant improvement noted
2 people found this helpful
I started taking the Vital B Complete Complex as I was perpetually exhausted and needed an energy boost. After just one week, I felt significantly more alert and less fatigued. My mood has stabilised, likely thanks to the B vitamins supporting my nervous system.
8
Eliminates fatigue
1 people found this helpful
I consider these daily supplements essential. Vitamin B makes a notable difference in my daily life. I feel it significantly helps in eliminating fatigue, as I can clearly tell when I am taking it versus when I am not. It is highly recommended!
7.5
Productivity increased
2 people found this helpful
One notable benefit is a significant increase in my energy levels. Taking the complex in the morning helps, and I feel more alert and active throughout the day. I noticed a marked improvement in my productivity; the fatigue episodes have diminished. B vitamins have evidently supported my nervous system, helping me react more calmly to stress, leading to a more stable mood.
7
We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
References
- Regland B, Forsmark S, Halaouate L, Matousek M, Peilot B, et al. Response to vitamin B12 and folic acid in myalgic encephalomyelitis and fibromyalgia. PLoS One. 2015;10:e0124648. 10.1371/journal.pone.0124648
