Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.2
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Thiamin (as Thiamin Mononitrate, Vitamin B-1)
100 mg
8,333%
Riboflavin (Vitamin B-2) 
100 mg
7,692%
Niacin (as Niacinamide)
100 mg
625%
Vitamin B-6 (as Pyridoxine HCl)
100 mg
5,882%
Folate
667 mcg DFE(400 mcg Folic Acid
167%
Vitamin B-12 (as Cyanocobalamin)
100 mcg
4,167%
Biotin
100 mcg
333%
Pantothenic Acid (as d-Calcium Pantothenate)
100 mg
2,000%
Calcium (as Calcium Carbonate & Dicalcium Phosphate)
124 mg
10%

Top Medical Research Studies

9
Cariban effectively relieves pregnancy nausea
We examined how Cariban, a combination of doxylamine and pyridoxine, helps alleviate nausea and vomiting during pregnancy. Using a controlled study involving 12 healthy women, we looked at how the modified-release capsules perform in the body compared to other forms.

Our findings showed that Cariban is absorbed quickly and maintains its effectiveness over an extended period. This makes it a reliable option for managing nausea in pregnant women, underscoring its value in clinical practice.
Read More
We examined a case involving an 82-year-old woman with advanced cervical cancer who experienced nausea and significant dietary intake decline. Her thiamine levels were critically low, indicating a deficiency that might have contributed to her condition.

After receiving 100 mg of thiamine intravenously, we observed notable improvements within a couple of hours. Her dietary intake increased significantly, from barely eating to nearly full meals. This suggests that addressing thiamine deficiency can positively impact the quality of life in patients receiving palliative care and highlights the importance of proper diagnosis.
Read More
We explored the effects of pyridoxine, or Vitamin B6, on nausea and vomiting during pregnancy, conditions known as NVP. By reviewing several studies, we found that Vitamin B6 supplementation, whether on its own or combined with other treatments, showed notable improvements in reducing nausea.

Out of 18 studies examined, eight demonstrated that pyridoxine alone is effective, while six indicated positive results when it was paired with other therapies.

Overall, our findings suggest that Vitamin B6 can be a helpful option for pregnant women dealing with these uncomfortable symptoms.
Read More

Most Useful Reviews

7.5
Relieved fatigue
1 people found this helpful
Good composition, fast delivery, and excellent packaging. Although the capsules are slightly large, I have no problem swallowing them; they have a citrus taste that I enjoy. I've been taking one daily with meals for ten days now, and I’ve noticed noticeable benefits. Before starting, I suffered from frequent headaches and nausea. Now, I have more energy and my mood is excellent throughout the day. It's a great supplement for those interested in fitness and diets.
Read More
0
Unsafe product
1 people found this helpful
The quality is very poor. I experienced nausea two hours after taking this supplement, and the vomiting lasted for four hours. Other products from this company are similarly inferior. Intended for good health, it instead makes you unhealthy. I strongly recommend safer products to avoid regret over cheap alternatives.
Read More
7.5
No nausea
An excellent vitamin B complex. It doesn’t cause nausea, unlike stress drug B, despite being similar in composition. Although I’m uncertain who can benefit, I noticed less rash before PMS.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
  • All Researches
We examined a case involving an 82-year-old woman with advanced cervical cancer who experienced nausea and significant dietary intake decline. Her thiamine levels were critically low, indicating a deficiency that might have contributed to her condition.

After receiving 100 mg of thiamine intravenously, we observed notable improvements within a couple of hours. Her dietary intake increased significantly, from barely eating to nearly full meals. This suggests that addressing thiamine deficiency can positively impact the quality of life in patients receiving palliative care and highlights the importance of proper diagnosis.
Read More
9
Cariban effectively relieves pregnancy nausea
We examined how Cariban, a combination of doxylamine and pyridoxine, helps alleviate nausea and vomiting during pregnancy. Using a controlled study involving 12 healthy women, we looked at how the modified-release capsules perform in the body compared to other forms.

Our findings showed that Cariban is absorbed quickly and maintains its effectiveness over an extended period. This makes it a reliable option for managing nausea in pregnant women, underscoring its value in clinical practice.
Read More
We explored the effects of pyridoxine, or Vitamin B6, on nausea and vomiting during pregnancy, conditions known as NVP. By reviewing several studies, we found that Vitamin B6 supplementation, whether on its own or combined with other treatments, showed notable improvements in reducing nausea.

Out of 18 studies examined, eight demonstrated that pyridoxine alone is effective, while six indicated positive results when it was paired with other therapies.

Overall, our findings suggest that Vitamin B6 can be a helpful option for pregnant women dealing with these uncomfortable symptoms.
Read More
7
Pyridoxine shows potential for PONV
We investigated whether pyridoxine, or vitamin B6, could help reduce postoperative nausea and vomiting (PONV) in patients after gynecological laparoscopic surgery. In our study, patients were split into two groups: one received pyridoxine while the other got a placebo.

Those who took pyridoxine, alongside standard medications, reported lower levels of nausea post-surgery. While the results show promise, further research in varied populations is essential for a more definitive conclusion.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 4 Reviews
7.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Relieved fatigue
1 people found this helpful
Good composition, fast delivery, and excellent packaging. Although the capsules are slightly large, I have no problem swallowing them; they have a citrus taste that I enjoy. I've been taking one daily with meals for ten days now, and I’ve noticed noticeable benefits. Before starting, I suffered from frequent headaches and nausea. Now, I have more energy and my mood is excellent throughout the day. It's a great supplement for those interested in fitness and diets.
Read More
0
Unsafe product
1 people found this helpful
The quality is very poor. I experienced nausea two hours after taking this supplement, and the vomiting lasted for four hours. Other products from this company are similarly inferior. Intended for good health, it instead makes you unhealthy. I strongly recommend safer products to avoid regret over cheap alternatives.
Read More
7.5
No nausea
An excellent vitamin B complex. It doesn’t cause nausea, unlike stress drug B, despite being similar in composition. Although I’m uncertain who can benefit, I noticed less rash before PMS.
Read More
0
Bad aftertaste
The taste is... I couldn't drink it because the aftertaste was so terrible that it caused nausea. I suggest making it easier to ingest.
Read More

Frequently Asked Questions

7.5
Relieved fatigue
1 people found this helpful
Good composition, fast delivery, and excellent packaging. Although the capsules are slightly large, I have no problem swallowing them; they have a citrus taste that I enjoy. I've been taking one daily with meals for ten days now, and I’ve noticed noticeable benefits. Before starting, I suffered from frequent headaches and nausea. Now, I have more energy and my mood is excellent throughout the day. It's a great supplement for those interested in fitness and diets.
0
Unsafe product
1 people found this helpful
The quality is very poor. I experienced nausea two hours after taking this supplement, and the vomiting lasted for four hours. Other products from this company are similarly inferior. Intended for good health, it instead makes you unhealthy. I strongly recommend safer products to avoid regret over cheap alternatives.
0
Bad aftertaste
The taste is... I couldn't drink it because the aftertaste was so terrible that it caused nausea. I suggest making it easier to ingest.
7.5
No nausea
An excellent vitamin B complex. It doesn’t cause nausea, unlike stress drug B, despite being similar in composition. Although I’m uncertain who can benefit, I noticed less rash before PMS.
7
Pyridoxine shows potential for PONV
We investigated whether pyridoxine, or vitamin B6, could help reduce postoperative nausea and vomiting (PONV) in patients after gynecological laparoscopic surgery. In our study, patients were split into two groups: one received pyridoxine while the other got a placebo.

Those who took pyridoxine, alongside standard medications, reported lower levels of nausea post-surgery. While the results show promise, further research in varied populations is essential for a more definitive conclusion.
We explored the effects of pyridoxine, or Vitamin B6, on nausea and vomiting during pregnancy, conditions known as NVP. By reviewing several studies, we found that Vitamin B6 supplementation, whether on its own or combined with other treatments, showed notable improvements in reducing nausea.

Out of 18 studies examined, eight demonstrated that pyridoxine alone is effective, while six indicated positive results when it was paired with other therapies.

Overall, our findings suggest that Vitamin B6 can be a helpful option for pregnant women dealing with these uncomfortable symptoms.
9
Cariban effectively relieves pregnancy nausea
We examined how Cariban, a combination of doxylamine and pyridoxine, helps alleviate nausea and vomiting during pregnancy. Using a controlled study involving 12 healthy women, we looked at how the modified-release capsules perform in the body compared to other forms.

Our findings showed that Cariban is absorbed quickly and maintains its effectiveness over an extended period. This makes it a reliable option for managing nausea in pregnant women, underscoring its value in clinical practice.
We examined a case involving an 82-year-old woman with advanced cervical cancer who experienced nausea and significant dietary intake decline. Her thiamine levels were critically low, indicating a deficiency that might have contributed to her condition.

After receiving 100 mg of thiamine intravenously, we observed notable improvements within a couple of hours. Her dietary intake increased significantly, from barely eating to nearly full meals. This suggests that addressing thiamine deficiency can positively impact the quality of life in patients receiving palliative care and highlights the importance of proper diagnosis.

References

  1. Zhang Q, Ye X, Shi S, Zhou S, Ma D, et al. Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecological Laparoscopic Surgery: A Double-blind Randomized Controlled Trial. Anesthesiology. 2024. 10.1097/ALN.0000000000005354
  2. Hayashi E, Matuura T, Takano J, Morofushi K, Toriizuka K, et al. Thiamine deficiency as a cause of anorexia in terminally ill cancer patients: A case of possible gastrointestinal beriberi. Palliat Support Care. 2024;22:1511. 10.1017/S1478951524000415
  3. Saz-Leal P, Zamorano-Domínguez L, Frías J, Guerra P, Saura-Valls M, et al. Bioavailability of Cariban Capsules: A Modified-Release Fixed-Dose Combination of Doxylamine and Pyridoxine to Relieve Nausea and Vomiting During Pregnancy. Drugs R D. 2023;23:185. 10.1007/s40268-023-00425-7
  4. Jayawardena R, Majeed S, Sooriyaarachchi P, Abeywarne U, Ranaweera P. The effects of pyridoxine (vitamin B6) supplementation in nausea and vomiting during pregnancy: a systematic review and meta-analysis. Arch Gynecol Obstet. 2023;308:1075. 10.1007/s00404-023-06925-w
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