Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
USERS' SCORE
Good
Based on 15 Reviews
8.5
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Thiamin (as Thiamin Mononitrate, Vitamin B-1)
100 mg
8,333%
Riboflavin (Vitamin B-2)
100 mg
7,692%
Niacin (as Niacinamide)
100 mg
625%
Vitamin B-6 (as Pyridoxine HCl)
100 mg
5,882%
Folate
667 mcg DFE(400 mcg Folic Acid
167%
Vitamin B-12 (as Cyanocobalamin)
100 mcg
4,167%
Biotin
100 mcg
333%
Pantothenic Acid (as d-Calcium Pantothenate)
100 mg
2,000%
Calcium (as Calcium Carbonate & Dicalcium Phosphate)
124 mg
10%
Top Medical Research Studies
9
We investigated how benfotiamine might impact stomach ulcers in male rats. The study involved dividing 30 rats into groups receiving different treatments, including benfotiamine at varying doses, following the induction of ulcers using indomethacin.
Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.
However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.
However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
Read More
8
We aimed to determine if ImproWin®, a feed additive, could help improve gastric ulcers in Standardbred and Coldblooded trotting racehorses. By conducting a randomized, double-blinded study, we assessed horses' ulcers before and after three weeks of treatment.
Our results showed a significant reduction in ulcer scores for horses treated with ImproWin®, with 78% classified as responders compared to only 54.8% in the placebo group. This indicates that ImproWin® may be beneficial for aiding the healing of gastric ulcers in affected racehorses.
Our results showed a significant reduction in ulcer scores for horses treated with ImproWin®, with 78% classified as responders compared to only 54.8% in the placebo group. This indicates that ImproWin® may be beneficial for aiding the healing of gastric ulcers in affected racehorses.
Read More
8
We examined how different doses of folic acid supplementation affect ulcer formation in rats. Male Wistar rats were treated with varying doses for 21 days while gastric ulcers were induced with indomethacin.
We found that a dose of 2 mg/kg significantly reduced gastric lesions, while a higher dose of 3 mg/kg unexpectedly worsened damage. Our results suggest that low doses of folic acid can be protective for the stomach, but high doses could pose risks.
Thus, it appears that moderation is key when considering folic acid for ulcer treatment.
We found that a dose of 2 mg/kg significantly reduced gastric lesions, while a higher dose of 3 mg/kg unexpectedly worsened damage. Our results suggest that low doses of folic acid can be protective for the stomach, but high doses could pose risks.
Thus, it appears that moderation is key when considering folic acid for ulcer treatment.
Read More
Most Useful Reviews
10
Immediate relief noted
2 people found this helpful
GOOD for mouth ulcers! After a vitamin-deficient holiday period, I had a mouth ulcer. I took it immediately, recalling I bought the B-100 from iHerb. Drinking in the morning made the inflammation subside by night. I was surprised by the immediate effect! This continuous release type is highly effective and recommended as a regular remedy.
Read More
10
Avoiding ulcers
I will continue to purchase this. If I'm not feeling well and miss my B100 intake, I tend to develop mouth ulcers soon after. I make a point to take it often. Previously, I frequently suffered from mouth ulcers, but now I don’t have them anymore, although the pills are quite large, and I sometimes bite them in half to swallow them more easily.
Read More
9
Prevents ulcers
For some time, my canker sores developed into ulcers, but after testing showed normal bacteria, I sought preventative measures. I purchased B-100, which has good cost performance. It’s true that my canker sores are less frequent and no longer worsen. I take one daily before bed and recommend it to anyone troubled by them.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
- All Researches
9.5
We analyzed the potential connection between folic acid supplementation and gastric ulcers using data from the UK Biobank and advanced statistical methods.
Our findings suggest that folic acid may significantly lower the risk of developing gastric ulcers.
Various robust models reinforced this result, showing consistent outcomes across different analyses.
Ultimately, this research provides genetic evidence supporting the idea that receiving folic acid therapy can be beneficial in reducing gastric ulcer risk.
Our findings suggest that folic acid may significantly lower the risk of developing gastric ulcers.
Various robust models reinforced this result, showing consistent outcomes across different analyses.
Ultimately, this research provides genetic evidence supporting the idea that receiving folic acid therapy can be beneficial in reducing gastric ulcer risk.
Read More
9
We investigated how benfotiamine might impact stomach ulcers in male rats. The study involved dividing 30 rats into groups receiving different treatments, including benfotiamine at varying doses, following the induction of ulcers using indomethacin.
Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.
However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.
However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
Read More
9
We explored the effects of Luffa acutangula extracts on gastric ulcers in diabetic rats. By inducing non-insulin dependent diabetes mellitus (NIDDM) and then creating gastric ulcers, we evaluated the extracts' potential for healing.
The results showed that the methanolic extract significantly boosted healing, improving protective mucosal glycoproteins and antioxidant levels. This was better than the aqueous extract and standard treatments.
Overall, Luffa acutangula appears to offer promising support for treating gastric ulcers in diabetes, highlighting its dual action in managing both conditions.
The results showed that the methanolic extract significantly boosted healing, improving protective mucosal glycoproteins and antioxidant levels. This was better than the aqueous extract and standard treatments.
Overall, Luffa acutangula appears to offer promising support for treating gastric ulcers in diabetes, highlighting its dual action in managing both conditions.
Read More
9
We explored the effectiveness of mecobalamin and vitamin E in treating recurrent oral ulcers. In a study with 58 patients, those receiving both treatments showed significantly improved healing times and reduced symptoms compared to the control group. They experienced longer periods without ulcer flare-ups and better quality of life scores. Both groups felt pain relief, but the test group had more noticeable benefits. This finding suggests that mecobalamin and vitamin E can be a valuable addition to ulcer treatment, enhancing both comfort and recovery.
Read More
8
We aimed to determine if ImproWin®, a feed additive, could help improve gastric ulcers in Standardbred and Coldblooded trotting racehorses. By conducting a randomized, double-blinded study, we assessed horses' ulcers before and after three weeks of treatment.
Our results showed a significant reduction in ulcer scores for horses treated with ImproWin®, with 78% classified as responders compared to only 54.8% in the placebo group. This indicates that ImproWin® may be beneficial for aiding the healing of gastric ulcers in affected racehorses.
Our results showed a significant reduction in ulcer scores for horses treated with ImproWin®, with 78% classified as responders compared to only 54.8% in the placebo group. This indicates that ImproWin® may be beneficial for aiding the healing of gastric ulcers in affected racehorses.
Read More
User Reviews
USERS' SCORE
Good
Based on 15 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
10
Immediate relief noted
2 people found this helpful
GOOD for mouth ulcers! After a vitamin-deficient holiday period, I had a mouth ulcer. I took it immediately, recalling I bought the B-100 from iHerb. Drinking in the morning made the inflammation subside by night. I was surprised by the immediate effect! This continuous release type is highly effective and recommended as a regular remedy.
Read More
10
Avoiding ulcers
I will continue to purchase this. If I'm not feeling well and miss my B100 intake, I tend to develop mouth ulcers soon after. I make a point to take it often. Previously, I frequently suffered from mouth ulcers, but now I don’t have them anymore, although the pills are quite large, and I sometimes bite them in half to swallow them more easily.
Read More
9
Prevents ulcers
For some time, my canker sores developed into ulcers, but after testing showed normal bacteria, I sought preventative measures. I purchased B-100, which has good cost performance. It’s true that my canker sores are less frequent and no longer worsen. I take one daily before bed and recommend it to anyone troubled by them.
Read More
8
Effective healing
I've been repeating myself because I wish to take B vitamins positively and appreciate its continuous release. Since starting this, I haven't had mouth ulcers, and the healing has occurred over time. It is a simple product to continue due to its good cost performance.
Read More
7.5
Mucous membrane repair
1 people found this helpful
What's good about this is that I often get mouth ulcers and swollen tonsils before the season or when unwell, but when I take this, the mucous membrane repairs quickly! I try not to consume too many sweet things, but when stressed, my B group seems to be depleted rapidly, and I begin to get mouth ulcers immediately, making this a good luck charm. The pills are not small, and B group is quickly metabolised, so I break them up with a cutter and take them accordingly.
Read More
Frequently Asked Questions
10
Immediate relief noted
2 people found this helpful
GOOD for mouth ulcers! After a vitamin-deficient holiday period, I had a mouth ulcer. I took it immediately, recalling I bought the B-100 from iHerb. Drinking in the morning made the inflammation subside by night. I was surprised by the immediate effect! This continuous release type is highly effective and recommended as a regular remedy.
10
Avoiding ulcers
I will continue to purchase this. If I'm not feeling well and miss my B100 intake, I tend to develop mouth ulcers soon after. I make a point to take it often. Previously, I frequently suffered from mouth ulcers, but now I don’t have them anymore, although the pills are quite large, and I sometimes bite them in half to swallow them more easily.
9
Prevents ulcers
For some time, my canker sores developed into ulcers, but after testing showed normal bacteria, I sought preventative measures. I purchased B-100, which has good cost performance. It’s true that my canker sores are less frequent and no longer worsen. I take one daily before bed and recommend it to anyone troubled by them.
7.5
Fast healing noted
4 people found this helpful
I take one tablet in the morning and one in the evening. My urine is yellow all day, indicating release. I've not noticed other effects, but my mouth ulcer healed quickly. While it makes my negative state zero, I wonder if I could create a positive from that.
9
Improved skin condition
No mouth ulcers When I drink this, my skin condition improves and I don't get mouth ulcers as often!
7.5
Less likely to occur
I bought this as I find it hard to get vitamin B from my diet. After starting the supplement, I feel that my mouth ulcers are less likely to occur.
7.5
Effective for skin
I'm pleased with both the ingredients and the price. I take it daily with other supplements and find it effective for rough skin and mouth ulcers.
7.5
Mucous membrane repair
1 people found this helpful
What's good about this is that I often get mouth ulcers and swollen tonsils before the season or when unwell, but when I take this, the mucous membrane repairs quickly! I try not to consume too many sweet things, but when stressed, my B group seems to be depleted rapidly, and I begin to get mouth ulcers immediately, making this a good luck charm. The pills are not small, and B group is quickly metabolised, so I break them up with a cutter and take them accordingly.
9.5
We analyzed the potential connection between folic acid supplementation and gastric ulcers using data from the UK Biobank and advanced statistical methods.
Our findings suggest that folic acid may significantly lower the risk of developing gastric ulcers.
Various robust models reinforced this result, showing consistent outcomes across different analyses.
Ultimately, this research provides genetic evidence supporting the idea that receiving folic acid therapy can be beneficial in reducing gastric ulcer risk.
Our findings suggest that folic acid may significantly lower the risk of developing gastric ulcers.
Various robust models reinforced this result, showing consistent outcomes across different analyses.
Ultimately, this research provides genetic evidence supporting the idea that receiving folic acid therapy can be beneficial in reducing gastric ulcer risk.
8
We examined how different doses of folic acid supplementation affect ulcer formation in rats. Male Wistar rats were treated with varying doses for 21 days while gastric ulcers were induced with indomethacin.
We found that a dose of 2 mg/kg significantly reduced gastric lesions, while a higher dose of 3 mg/kg unexpectedly worsened damage. Our results suggest that low doses of folic acid can be protective for the stomach, but high doses could pose risks.
Thus, it appears that moderation is key when considering folic acid for ulcer treatment.
We found that a dose of 2 mg/kg significantly reduced gastric lesions, while a higher dose of 3 mg/kg unexpectedly worsened damage. Our results suggest that low doses of folic acid can be protective for the stomach, but high doses could pose risks.
Thus, it appears that moderation is key when considering folic acid for ulcer treatment.
9
We investigated how benfotiamine might impact stomach ulcers in male rats. The study involved dividing 30 rats into groups receiving different treatments, including benfotiamine at varying doses, following the induction of ulcers using indomethacin.
Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.
However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.
However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
8
We explored the effects of nicotinamide on gastric ulcers caused by indomethacin in a laboratory setting. Using a well-established model, we compared the treatment of nicotinamide with sucralfate, a known antiulcer drug.
Our findings revealed that nicotinamide significantly reduced the severity of gastric lesions. It also helped restore vital biochemical parameters affected by the ulcer-inducing drug.
The protective effect of nicotinamide appears to stem from its ability to conserve gastric mucus and nitric oxide, improve gastric microvascular permeability, and exert antioxidant actions.
Our findings revealed that nicotinamide significantly reduced the severity of gastric lesions. It also helped restore vital biochemical parameters affected by the ulcer-inducing drug.
The protective effect of nicotinamide appears to stem from its ability to conserve gastric mucus and nitric oxide, improve gastric microvascular permeability, and exert antioxidant actions.
References
- Li F, Huang F, Tang Y, Zhang F, Jiang H, et al. Causal association of folic acid supplementary therapy and gastric ulcer: a Mendelian randomisation study. Br J Nutr. 2024;132:1348. doi:10.1017/S0007114524002368
- Shokati Sayyad M, Khanjani MH, Amirbeik M, Seyedabadi M, Talebpour Amiri F, et al. The protective effect of benfotiamine on gastric ulcers in male rats: an experimental study. J Mol Histol. 2024;55:863. doi:10.1007/s10735-024-10237-x
- Hellings IR, Larsen S. ImproWin® in the treatment of gastric ulceration of the squamous mucosa in trotting racehorses. Acta Vet Scand. 2014;56:13. doi:10.1186/1751-0147-56-13
- Ajeigbe K, Oladejo E, Emikpe B, Asuk A, Olaleye S. The dual modulatory effect of folic acid supplementation on indomethacin-induced gastropathy in the rat. Turk J Gastroenterol. 2012;23:639.
- Pimple BP, Kadam PV, Patil MJ. Protective effect of Luffa acutangula extracts on gastric ulceration in NIDDM rats: role of gastric mucosal glycoproteins and antioxidants. Asian Pac J Trop Med. 2012;5:610. doi:10.1016/S1995-7645(12)60126-6
- Abdallah DM. Nicotinamide alleviates indomethacin-induced gastric ulcers: a novel antiulcer agent. Eur J Pharmacol. 2010;627:276. doi:10.1016/j.ejphar.2009.10.037
- Cui J, Lin W, Ma X, Wang J. Clinical Evaluation and Therapeutic Effects of Combination Treatment with Mecobalamin + Vitamin E in Recurrent Oral Ulcer. Clin Ther. 2022;44:123. doi:10.1016/j.clinthera.2021.10.015
