Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
5.5
USERS' SCORE
Good
Based on 12 Reviews
8.3
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Folate
667 mcg DFE (400 mcg Folic Acid)
167%
Calcium (as Calcium Carbonate)
100 mg
8%
Top Medical Research Studies
7
Folic acid alleviates gastric hypersensitivity
We investigated how folic acid (FA) impacts gastric hypersensitivity caused by prenatal stress. Through a series of experiments involving nerve recordings and molecular analysis, we found that FA significantly alleviated symptoms related to gastric hypersensitivity.
It worked by boosting the expression of DNMT1, which in turn reduced the activity of ASIC1, a key molecule involved in pain sensation. While promising, further research is essential as this study primarily focuses on rats. The findings may pave the way for potential treatments in humans.
It worked by boosting the expression of DNMT1, which in turn reduced the activity of ASIC1, a key molecule involved in pain sensation. While promising, further research is essential as this study primarily focuses on rats. The findings may pave the way for potential treatments in humans.
Read More
4
Methyl donors may increase allergy risk
We examined how late-gestation maternal supplementation with methyl donors impacts allergic sensitivity in offspring from pregnancies with restricted growth (IUGR).
Our study compared allergic responses in three groups of sheep: those from normal pregnancies, those from PR pregnancies without supplementation, and those whose mothers received the supplementation.
Interestingly, while the IUGR pregnancies showed protection against allergies, the methyl donor supplementation did not change this advantage. In fact, it resulted in more upper dermal mast cells but did not alter overall allergic reactions or birth size.
These findings indicate that while IUGR may limit allergy risk, adding methyl donors might potentially increase it instead.
Our study compared allergic responses in three groups of sheep: those from normal pregnancies, those from PR pregnancies without supplementation, and those whose mothers received the supplementation.
Interestingly, while the IUGR pregnancies showed protection against allergies, the methyl donor supplementation did not change this advantage. In fact, it resulted in more upper dermal mast cells but did not alter overall allergic reactions or birth size.
These findings indicate that while IUGR may limit allergy risk, adding methyl donors might potentially increase it instead.
Read More
Most Useful Reviews
7.5
Reduced allergy symptoms
90 people found this helpful
Excellent! I feel much better taking this every day. I had quite severe allergies, but after starting it, my symptoms have diminished, and I've been sick less often. If you're seeking a way to improve your health, this is it!
Read More
9
No allergies experienced
1 people found this helpful
I liked it; it did not cause allergies.
Read More
9
Beneficial alternative
1 people found this helpful
I preferred Solgar regarding shape, but this is a good and more beneficial alternative. It didn't provoke any allergies.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
5.5
- All Researches
7
Folic acid alleviates gastric hypersensitivity
We investigated how folic acid (FA) impacts gastric hypersensitivity caused by prenatal stress. Through a series of experiments involving nerve recordings and molecular analysis, we found that FA significantly alleviated symptoms related to gastric hypersensitivity.
It worked by boosting the expression of DNMT1, which in turn reduced the activity of ASIC1, a key molecule involved in pain sensation. While promising, further research is essential as this study primarily focuses on rats. The findings may pave the way for potential treatments in humans.
It worked by boosting the expression of DNMT1, which in turn reduced the activity of ASIC1, a key molecule involved in pain sensation. While promising, further research is essential as this study primarily focuses on rats. The findings may pave the way for potential treatments in humans.
Read More
4
Methyl donors may increase allergy risk
We examined how late-gestation maternal supplementation with methyl donors impacts allergic sensitivity in offspring from pregnancies with restricted growth (IUGR).
Our study compared allergic responses in three groups of sheep: those from normal pregnancies, those from PR pregnancies without supplementation, and those whose mothers received the supplementation.
Interestingly, while the IUGR pregnancies showed protection against allergies, the methyl donor supplementation did not change this advantage. In fact, it resulted in more upper dermal mast cells but did not alter overall allergic reactions or birth size.
These findings indicate that while IUGR may limit allergy risk, adding methyl donors might potentially increase it instead.
Our study compared allergic responses in three groups of sheep: those from normal pregnancies, those from PR pregnancies without supplementation, and those whose mothers received the supplementation.
Interestingly, while the IUGR pregnancies showed protection against allergies, the methyl donor supplementation did not change this advantage. In fact, it resulted in more upper dermal mast cells but did not alter overall allergic reactions or birth size.
These findings indicate that while IUGR may limit allergy risk, adding methyl donors might potentially increase it instead.
Read More
User Reviews
USERS' SCORE
Good
Based on 12 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Reduced allergy symptoms
90 people found this helpful
Excellent! I feel much better taking this every day. I had quite severe allergies, but after starting it, my symptoms have diminished, and I've been sick less often. If you're seeking a way to improve your health, this is it!
Read More
9
No allergies experienced
1 people found this helpful
I liked it; it did not cause allergies.
Read More
9
Beneficial alternative
1 people found this helpful
I preferred Solgar regarding shape, but this is a good and more beneficial alternative. It didn't provoke any allergies.
Read More
9
Good value tablets
Small tablets with a good amount of folic acid. They do not provoke allergies. A bargain! I highly recommend them.
Read More
9
Hypoallergenic quality
This product has a lovely scent, is easy to use, and of excellent quality. It is suitable for those over 18 and well-packaged. Importantly, it does not cause allergies and gently moisturises the skin, making it a great choice for personal care.
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Frequently Asked Questions
7.5
Reduced allergy symptoms
90 people found this helpful
Excellent! I feel much better taking this every day. I had quite severe allergies, but after starting it, my symptoms have diminished, and I've been sick less often. If you're seeking a way to improve your health, this is it!
9
No allergies experienced
1 people found this helpful
I liked it; it did not cause allergies.
9
Beneficial alternative
1 people found this helpful
I preferred Solgar regarding shape, but this is a good and more beneficial alternative. It didn't provoke any allergies.
9
Improved immunity
I purchased this for my 12-year-old son. The ingredients are excellent, and it boosts immunity while improving health. The tablet is small and easy to swallow, and it does not trigger allergies. I would recommend it to everyone.
9
No allergies
Fine Vitamins seem to be effective, as they are absorbed well and have not caused any allergies.
9
No allergies
The dosage is suitable for my son with CF, and it helps with iron absorption. No allergies occurred.
9
Gentle formula
Usage should be discussed with a doctor. The product is well-sized and of high quality. It is beneficial and gentle on the skin, with a good formula. I have not experienced any allergies.
References
- Wang HJ, Zhang FC, Xu TW, Xu YC, Tian YQ, et al. DNMT1 involved in the analgesic effect of folic acid on gastric hypersensitivity through downregulating ASIC1 in adult offspring rats with prenatal maternal stress. CNS Neurosci Ther. 2023;29:1678. 10.1111/cns.14131
- Wooldridge AL, Bischof RJ, Liu H, Heinemann GK, Hunter DS, et al. Late-gestation maternal dietary methyl donor and cofactor supplementation in sheep partially reverses protection against allergic sensitization by IUGR. Am J Physiol Regul Integr Comp Physiol. 2018;314:R22. 10.1152/ajpregu.00549.2016
