Last update
5/22/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.1
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Folate
667 mcg DFE (400 mcg Folic Acid)
167%
Calcium (as Calcium Carbonate)
100 mg
8%
Top Medical Research Studies
8
We examined a patient who experienced severe anemia following COVID-19, presenting with both cold agglutinin and cryoglobulin. Testing showed positivity for C3d but no significant signs of hemolytic anemia or thrombosis.
Remarkably, the anemia improved with just folic acid supplementation, which also reduced the cold agglutination levels and normalized the direct antiglobulin test. Although cryoglobulinemia persisted, the patient remained symptom-free.
This suggests that thorough assessment is crucial before considering treatments for cold-related blood disorders following COVID-19.
Remarkably, the anemia improved with just folic acid supplementation, which also reduced the cold agglutination levels and normalized the direct antiglobulin test. Although cryoglobulinemia persisted, the patient remained symptom-free.
This suggests that thorough assessment is crucial before considering treatments for cold-related blood disorders following COVID-19.
Read More
Most Useful Reviews
7.5
Feeling better overall
1 people found this helpful
I started feeling cold and depressed, so I researched and learned that a folic acid deficiency could lead to depression. I began taking it as a supplement. After about a month, I haven't caught a cold, which suggests it’s working well. My mood has also improved.
Read More
6
Less colds noted
90 people found this helpful
Excellent! I have been taking these vitamins for a few weeks now and feel like this is the start of something new. I no longer feel tired and in pain, and my mood has considerably improved! I even noticed that I am less likely to catch a cold than before. These vitamins are remarkable!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We examined a patient who experienced severe anemia following COVID-19, presenting with both cold agglutinin and cryoglobulin. Testing showed positivity for C3d but no significant signs of hemolytic anemia or thrombosis.
Remarkably, the anemia improved with just folic acid supplementation, which also reduced the cold agglutination levels and normalized the direct antiglobulin test. Although cryoglobulinemia persisted, the patient remained symptom-free.
This suggests that thorough assessment is crucial before considering treatments for cold-related blood disorders following COVID-19.
Remarkably, the anemia improved with just folic acid supplementation, which also reduced the cold agglutination levels and normalized the direct antiglobulin test. Although cryoglobulinemia persisted, the patient remained symptom-free.
This suggests that thorough assessment is crucial before considering treatments for cold-related blood disorders following COVID-19.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Feeling better overall
1 people found this helpful
I started feeling cold and depressed, so I researched and learned that a folic acid deficiency could lead to depression. I began taking it as a supplement. After about a month, I haven't caught a cold, which suggests it’s working well. My mood has also improved.
Read More
6
Less colds noted
90 people found this helpful
Excellent! I have been taking these vitamins for a few weeks now and feel like this is the start of something new. I no longer feel tired and in pain, and my mood has considerably improved! I even noticed that I am less likely to catch a cold than before. These vitamins are remarkable!
Read More
Frequently Asked Questions
7.5
Feeling better overall
1 people found this helpful
I started feeling cold and depressed, so I researched and learned that a folic acid deficiency could lead to depression. I began taking it as a supplement. After about a month, I haven't caught a cold, which suggests it’s working well. My mood has also improved.
6
Less colds noted
90 people found this helpful
Excellent! I have been taking these vitamins for a few weeks now and feel like this is the start of something new. I no longer feel tired and in pain, and my mood has considerably improved! I even noticed that I am less likely to catch a cold than before. These vitamins are remarkable!
References
- Kaneko M, Masuda Y, Ishikawa K, Shikata H. Coexistence of Cold Agglutinin and Cryoglobulin in a Patient With Severe Anemia Following COVID-19 Infection. Cureus. 2024;16:e75257. 10.7759/cureus.75257
