Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
USERS' SCORE
Good
Based on 25 Reviews
8.5
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Gelatin (as capsule fill and capsule shell)
600 mg
**

Top Medical Research Studies

In our study, we explored the impact of collagen peptide (CP) supplementation on knee pain and daily functioning among active middle-aged adults. Conducted as a double-blind randomized control trial, participants received either a placebo or varying dosages of CP for six to nine months.

We observed that a daily intake of 10 grams of CP significantly improved activity levels and reduced pain in highly active individuals. Additionally, mental and physical health assessments showed positive outcomes, particularly in women taking 20 grams of CP. Overall, results indicate potential improvements in quality of life from collagen supplementation.
Read More
7
Gelatin shows promise for knee pain
We evaluated how well quick-soluble gelatin sponge particles help relieve chronic knee pain from osteoarthritis through a procedure called genicular artery embolization (GAE). In this study, 71 patients underwent 97 procedures, achieving a 100% technical success rate.

We observed a significant drop in pain levels over six months, with 72% of patients experiencing a notable improvement. While there were no major health risks, some minor side effects were noted. Overall, GAE with gelatin proved effective and safe for chronic knee pain.
Read More
7
Collagen hydrolysate shows potential benefits
We explored the potential of collagen hydrolysate, particularly as a treatment for osteoarthritis and osteoporosis. After reviewing existing studies, we found that daily consumption of 10 grams of pharmaceutical-grade collagen hydrolysate may help reduce knee pain.

Interestingly, some results showed a notable benefit in specific regions, like Germany, and in patients with more severe symptoms. While its safety profile is favorable, the overall data indicated no major differences in pain relief when comparing collagen with a placebo across all clinics.

This suggests that, while promising, collagen hydrolysate’s effectiveness may vary among individuals.
Read More

Most Useful Reviews

9
Knee pain relief
3 people found this helpful
After just a week, my nails are stronger, and my hair is thicker with less loss during washing. I bought it to help rebuild the cartilage in my knees, and it's effective; my knees no longer creak or ache. The improvement was quick and it's such an affordable solution!
Read More
9
Pain relief miracle
1 people found this helpful
Excellent! This has become my go-to solution for achy joints. I now take it three times daily and have found it essential as I age and encounter more toxins. After a month of consistent use, I noticed a remarkable difference; my ability to use my hands and walk improved significantly. Without it, I'd struggle with severe knee pain.
Read More
9
Miracle for pain
1 people found this helpful
This product helped me with long-lasting joint pain in my middle finger. I have been taking two capsules of gelatin per day after meals for two weeks, and now the pain has vanished. I'm thrilled and grateful for this miracle.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
  • All Researches
In our study, we explored the impact of collagen peptide (CP) supplementation on knee pain and daily functioning among active middle-aged adults. Conducted as a double-blind randomized control trial, participants received either a placebo or varying dosages of CP for six to nine months.

We observed that a daily intake of 10 grams of CP significantly improved activity levels and reduced pain in highly active individuals. Additionally, mental and physical health assessments showed positive outcomes, particularly in women taking 20 grams of CP. Overall, results indicate potential improvements in quality of life from collagen supplementation.
Read More
7
Gelatin shows promise for knee pain
We evaluated how well quick-soluble gelatin sponge particles help relieve chronic knee pain from osteoarthritis through a procedure called genicular artery embolization (GAE). In this study, 71 patients underwent 97 procedures, achieving a 100% technical success rate.

We observed a significant drop in pain levels over six months, with 72% of patients experiencing a notable improvement. While there were no major health risks, some minor side effects were noted. Overall, GAE with gelatin proved effective and safe for chronic knee pain.
Read More
7
Knee pain management study outcomes
We compared the effectiveness of gelatin microspheres to Imipenem/Cilastatin in providing pain relief through genicular artery embolization in patients suffering from moderate to severe knee osteoarthritis.

In a study involving 14 patients, we found that both treatments significantly reduced knee pain over a follow-up period of two years, as measured by the WOMAC questionnaire. The reduction in pain was maintained over this period, with no major adverse events reported.

Ultimately, we concluded that gelatin microspheres could be a viable alternative for knee pain management, offering sustained relief comparable to traditional treatments.
Read More
We examined several studies investigating the effects of collagen derivatives, including gelatin, on knee pain related to osteoarthritis (OA). While some results indicated benefits, particularly from gelatin in reducing pain, the evidence remains mixed and does not consistently support its widespread use.

Overall, the studies showed limited to moderate quality, with insufficient evidence to endorse collagen hydrolysates in daily practice for OA treatment. Major improvements are needed through more rigorous research to truly understand how these options might help those suffering from knee pain.
Read More
7
Collagen hydrolysate shows potential benefits
We explored the potential of collagen hydrolysate, particularly as a treatment for osteoarthritis and osteoporosis. After reviewing existing studies, we found that daily consumption of 10 grams of pharmaceutical-grade collagen hydrolysate may help reduce knee pain.

Interestingly, some results showed a notable benefit in specific regions, like Germany, and in patients with more severe symptoms. While its safety profile is favorable, the overall data indicated no major differences in pain relief when comparing collagen with a placebo across all clinics.

This suggests that, while promising, collagen hydrolysate’s effectiveness may vary among individuals.
Read More

User Reviews

USERS' SCORE
Good
Based on 25 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Knee pain relief
3 people found this helpful
After just a week, my nails are stronger, and my hair is thicker with less loss during washing. I bought it to help rebuild the cartilage in my knees, and it's effective; my knees no longer creak or ache. The improvement was quick and it's such an affordable solution!
Read More
9
Pain relief miracle
1 people found this helpful
Excellent! This has become my go-to solution for achy joints. I now take it three times daily and have found it essential as I age and encounter more toxins. After a month of consistent use, I noticed a remarkable difference; my ability to use my hands and walk improved significantly. Without it, I'd struggle with severe knee pain.
Read More
9
Miracle for pain
1 people found this helpful
This product helped me with long-lasting joint pain in my middle finger. I have been taking two capsules of gelatin per day after meals for two weeks, and now the pain has vanished. I'm thrilled and grateful for this miracle.
Read More
9
Indispensable for pain
1 people found this helpful
Good for anyone with knee pain. It’s absolutely indispensable, and I purchased it for all my friends too.
Read More
9
Effective for arthrosis
1 people found this helpful
I drink it for support due to my diagnosis of arthrosis in knee joints. After two years of periodic intake, it has stopped bothering me. Gelatin genuinely helped! I take six capsules on an empty stomach with 250 mg of vitamin C, and I’ve had no unpleasant consequences. Health to all!
Read More

Frequently Asked Questions

9
Knee pain relief
3 people found this helpful
After just a week, my nails are stronger, and my hair is thicker with less loss during washing. I bought it to help rebuild the cartilage in my knees, and it's effective; my knees no longer creak or ache. The improvement was quick and it's such an affordable solution!
9
Pain relief miracle
1 people found this helpful
Excellent! This has become my go-to solution for achy joints. I now take it three times daily and have found it essential as I age and encounter more toxins. After a month of consistent use, I noticed a remarkable difference; my ability to use my hands and walk improved significantly. Without it, I'd struggle with severe knee pain.
7.5
Crunchy knees improved
10 people found this helpful
I need it; my knees are crunchy. After two weeks, I've noticed an improvement, and my nails are also better.
6
Improvement over time
2 people found this helpful
I love this quality collagen. It's recommended to take 2 tablets three times daily for optimal benefits, which become more noticeable after three months. I’ve seen improvements in my skin and knee condition. The price is reasonable, and the composition is great.
7.5
Knees bending normally
1 people found this helpful
My knees began to hurt a lot, and I tried all prescribed drugs, compresses, lotions, and rubbing. They had only a temporary effect. Then my wife brought Gelatin 21 St Century, which I started taking three times a day. Now, my knees bend normally. I didn’t believe in supplements, but now I will buy more from this company!
9
Beauty benefits noted
13 people found this helpful
An excellent product for enhancing the beauty of hair, nails, and skin. I take one capsule twice daily, and I’ve noticed that the crunching in my knees has stopped. It’s superb!
9
Effective for arthrosis
1 people found this helpful
I drink it for support due to my diagnosis of arthrosis in knee joints. After two years of periodic intake, it has stopped bothering me. Gelatin genuinely helped! I take six capsules on an empty stomach with 250 mg of vitamin C, and I’ve had no unpleasant consequences. Health to all!
7.5
No more aches
1 people found this helpful
I drink gelatin myself, combined with biotin for hair and skin. My husband takes two capsules a day for his joints, and he mentioned his knee does not ache anymore with the weather!
7.5
Reduced noise and pain
1 people found this helpful
My mother-in-law, aged 65, has been taking this alongside collagen every six months for the past two years. She reports that her knees have stopped crackling, and her back and arms hurt considerably less.
In our study, we explored the impact of collagen peptide (CP) supplementation on knee pain and daily functioning among active middle-aged adults. Conducted as a double-blind randomized control trial, participants received either a placebo or varying dosages of CP for six to nine months.

We observed that a daily intake of 10 grams of CP significantly improved activity levels and reduced pain in highly active individuals. Additionally, mental and physical health assessments showed positive outcomes, particularly in women taking 20 grams of CP. Overall, results indicate potential improvements in quality of life from collagen supplementation.
7
Gelatin shows promise for knee pain
We evaluated how well quick-soluble gelatin sponge particles help relieve chronic knee pain from osteoarthritis through a procedure called genicular artery embolization (GAE). In this study, 71 patients underwent 97 procedures, achieving a 100% technical success rate.

We observed a significant drop in pain levels over six months, with 72% of patients experiencing a notable improvement. While there were no major health risks, some minor side effects were noted. Overall, GAE with gelatin proved effective and safe for chronic knee pain.
7
Knee pain management study outcomes
We compared the effectiveness of gelatin microspheres to Imipenem/Cilastatin in providing pain relief through genicular artery embolization in patients suffering from moderate to severe knee osteoarthritis.

In a study involving 14 patients, we found that both treatments significantly reduced knee pain over a follow-up period of two years, as measured by the WOMAC questionnaire. The reduction in pain was maintained over this period, with no major adverse events reported.

Ultimately, we concluded that gelatin microspheres could be a viable alternative for knee pain management, offering sustained relief comparable to traditional treatments.
We examined several studies investigating the effects of collagen derivatives, including gelatin, on knee pain related to osteoarthritis (OA). While some results indicated benefits, particularly from gelatin in reducing pain, the evidence remains mixed and does not consistently support its widespread use.

Overall, the studies showed limited to moderate quality, with insufficient evidence to endorse collagen hydrolysates in daily practice for OA treatment. Major improvements are needed through more rigorous research to truly understand how these options might help those suffering from knee pain.
7
Collagen hydrolysate shows potential benefits
We explored the potential of collagen hydrolysate, particularly as a treatment for osteoarthritis and osteoporosis. After reviewing existing studies, we found that daily consumption of 10 grams of pharmaceutical-grade collagen hydrolysate may help reduce knee pain.

Interestingly, some results showed a notable benefit in specific regions, like Germany, and in patients with more severe symptoms. While its safety profile is favorable, the overall data indicated no major differences in pain relief when comparing collagen with a placebo across all clinics.

This suggests that, while promising, collagen hydrolysate’s effectiveness may vary among individuals.

References

  1. Kviatkovsky SA, Hickner RC, Cabre HE, Small SD, Ormsbee MJ. Collagen peptides supplementation improves function, pain, and physical and mental outcomes in active adults. J Int Soc Sports Nutr. 2023;20:2243252. 10.1080/15502783.2023.2243252
  2. Min J, Park SW, Hwang JH, Lee JK, Lee DW, et al. Evaluating the Safety and Effectiveness of Quick-Soluble Gelatin Sponge Particles for Genicular Artery Embolization for Chronic Knee Pain Associated with Osteoarthritis. J Vasc Interv Radiol. 2023;34:1868. 10.1016/j.jvir.2023.07.009
  3. Bhatia S, Jalaeian H, Kumar J, Acharya V, Shibuya M, et al. Two-year outcomes comparing Embosphere® microspheres versus Imipenem Cilastatin for genicular artery embolization in patients with moderate to severe knee osteoarthritis. Knee. 2023;41:38. 10.1016/j.knee.2022.12.008
  4. Van Vijven JP, Luijsterburg PA, Verhagen AP, van Osch GJ, Kloppenburg M, et al. Symptomatic and chondroprotective treatment with collagen derivatives in osteoarthritis: a systematic review. Osteoarthritis Cartilage. 2012;20:809. 10.1016/j.joca.2012.04.008
  5. Moskowitz RW. Role of collagen hydrolysate in bone and joint disease. Semin Arthritis Rheum. 2000;30:87.
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