5/27/2025
Last update
5/27/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Niacin
500 mg
3,125%
Top Medical Research Studies
8
We aimed to understand the relationship between niacin intake and osteoarthritis (OA) by analyzing data from the National Health and Nutrition Examination Survey spanning from 1999 to 2018. With over 30,000 participants in the study and almost 2,000 diagnosed with osteoarthritis, we found some interesting results.
Our analysis used advanced statistical methods to explore how different levels of niacin intake affected the risk of developing OA. What we discovered was that higher niacin intake was consistently associated with a reduced risk of osteoarthritis. In fact, participants in the highest intake group had a remarkable 33% lower risk compared to those in the lowest intake group.
We also noticed that there’s a non-linear relationship; once we reach an inflection point in niacin intake, the way it impacts OA risk changes. The results were particularly striking in Non-Hispanic Black individuals and others in different racial groups.
Overall, this research suggests that by increasing the consumption of niacin-rich foods, we may be able to reduce the risk of developing osteoarthritis. However, further investigations are needed to confirm these findings and explore the potential of niacin as an effective dietary approach to OA prevention and treatment.
Our analysis used advanced statistical methods to explore how different levels of niacin intake affected the risk of developing OA. What we discovered was that higher niacin intake was consistently associated with a reduced risk of osteoarthritis. In fact, participants in the highest intake group had a remarkable 33% lower risk compared to those in the lowest intake group.
We also noticed that there’s a non-linear relationship; once we reach an inflection point in niacin intake, the way it impacts OA risk changes. The results were particularly striking in Non-Hispanic Black individuals and others in different racial groups.
Overall, this research suggests that by increasing the consumption of niacin-rich foods, we may be able to reduce the risk of developing osteoarthritis. However, further investigations are needed to confirm these findings and explore the potential of niacin as an effective dietary approach to OA prevention and treatment.
Read More
8
We explored the relationship between dietary niacin intake and rheumatoid arthritis (RA) in American women using data from the National Health and Nutrition Examination Survey. By analyzing data collected from 2003 to 2016, we aimed to understand whether higher levels of niacin could lead to a decrease in the prevalence of RA.
Our findings revealed that women with RA had lower dietary niacin intakes compared to those without the condition. Specifically, we observed a significant negative correlation between niacin intake and the likelihood of having RA. This means that as dietary niacin intake increased, the odds of having RA decreased.
Notably, we found that the association was particularly strong among women aged 40 and above, those with a poverty income ratio greater than 3.5, women with at least a college education, and individuals who were obese or non-smokers. These insights suggest that dietary niacin could be an important dietary consideration for reducing the risk of RA in specific groups of women.
Our findings revealed that women with RA had lower dietary niacin intakes compared to those without the condition. Specifically, we observed a significant negative correlation between niacin intake and the likelihood of having RA. This means that as dietary niacin intake increased, the odds of having RA decreased.
Notably, we found that the association was particularly strong among women aged 40 and above, those with a poverty income ratio greater than 3.5, women with at least a college education, and individuals who were obese or non-smokers. These insights suggest that dietary niacin could be an important dietary consideration for reducing the risk of RA in specific groups of women.
Read More
Most Useful Reviews
9
Effective remedy
3 people found this helpful
Dr Recommended this to me. I’ve added this product to my daily regimen at my dermatologist’s suggestion to help with psoriatic arthritis. It has worked wonders. I now take it twice daily and will never stop using this product.
Read More
9
Pain relief
5 people found this helpful
So happy I tried this! My osteoarthritis was significantly affecting my right hand. After using Niacinamide, the pain has vanished. I read about its benefits and decided to try it, as I prefer avoiding many prescription drugs. I’m delighted with the results.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
- All Researches
8
We aimed to understand the relationship between niacin intake and osteoarthritis (OA) by analyzing data from the National Health and Nutrition Examination Survey spanning from 1999 to 2018. With over 30,000 participants in the study and almost 2,000 diagnosed with osteoarthritis, we found some interesting results.
Our analysis used advanced statistical methods to explore how different levels of niacin intake affected the risk of developing OA. What we discovered was that higher niacin intake was consistently associated with a reduced risk of osteoarthritis. In fact, participants in the highest intake group had a remarkable 33% lower risk compared to those in the lowest intake group.
We also noticed that there’s a non-linear relationship; once we reach an inflection point in niacin intake, the way it impacts OA risk changes. The results were particularly striking in Non-Hispanic Black individuals and others in different racial groups.
Overall, this research suggests that by increasing the consumption of niacin-rich foods, we may be able to reduce the risk of developing osteoarthritis. However, further investigations are needed to confirm these findings and explore the potential of niacin as an effective dietary approach to OA prevention and treatment.
Our analysis used advanced statistical methods to explore how different levels of niacin intake affected the risk of developing OA. What we discovered was that higher niacin intake was consistently associated with a reduced risk of osteoarthritis. In fact, participants in the highest intake group had a remarkable 33% lower risk compared to those in the lowest intake group.
We also noticed that there’s a non-linear relationship; once we reach an inflection point in niacin intake, the way it impacts OA risk changes. The results were particularly striking in Non-Hispanic Black individuals and others in different racial groups.
Overall, this research suggests that by increasing the consumption of niacin-rich foods, we may be able to reduce the risk of developing osteoarthritis. However, further investigations are needed to confirm these findings and explore the potential of niacin as an effective dietary approach to OA prevention and treatment.
Read More
8
We explored the relationship between dietary niacin intake and rheumatoid arthritis (RA) in American women using data from the National Health and Nutrition Examination Survey. By analyzing data collected from 2003 to 2016, we aimed to understand whether higher levels of niacin could lead to a decrease in the prevalence of RA.
Our findings revealed that women with RA had lower dietary niacin intakes compared to those without the condition. Specifically, we observed a significant negative correlation between niacin intake and the likelihood of having RA. This means that as dietary niacin intake increased, the odds of having RA decreased.
Notably, we found that the association was particularly strong among women aged 40 and above, those with a poverty income ratio greater than 3.5, women with at least a college education, and individuals who were obese or non-smokers. These insights suggest that dietary niacin could be an important dietary consideration for reducing the risk of RA in specific groups of women.
Our findings revealed that women with RA had lower dietary niacin intakes compared to those without the condition. Specifically, we observed a significant negative correlation between niacin intake and the likelihood of having RA. This means that as dietary niacin intake increased, the odds of having RA decreased.
Notably, we found that the association was particularly strong among women aged 40 and above, those with a poverty income ratio greater than 3.5, women with at least a college education, and individuals who were obese or non-smokers. These insights suggest that dietary niacin could be an important dietary consideration for reducing the risk of RA in specific groups of women.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective remedy
3 people found this helpful
Dr Recommended this to me. I’ve added this product to my daily regimen at my dermatologist’s suggestion to help with psoriatic arthritis. It has worked wonders. I now take it twice daily and will never stop using this product.
Read More
9
Pain relief
5 people found this helpful
So happy I tried this! My osteoarthritis was significantly affecting my right hand. After using Niacinamide, the pain has vanished. I read about its benefits and decided to try it, as I prefer avoiding many prescription drugs. I’m delighted with the results.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Lv X, Deng X, Lai R, Liu S, Zou Z, et al. Association between niacin intake and osteoarthritis in the US population based on NHANES 1999-2018. Sci Rep. 2025;15:6470. 10.1038/s41598-025-91063-3
- Hong X, Jiang F. Association Between Dietary Niacin Intake and Rheumatoid Arthritis in American Women: A Study Based on National Health and Nutrition Examination Survey Database. Int J Womens Health. 2024;16:2209. 10.2147/IJWH.S482294
