' 
SCIENTIFIC SCORE
Likely Ineffective
Based on 1 Research
3
USERS' SCORE
Good
Based on 4 Reviews
8.7
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Niacin
500 mg
3,125%
Top Medical Research Studies
3
Nicotinamide shows limited effectiveness
The Role of Nicotinamide as Chemo-Preventive Agent in NMSCs: A Systematic Review and Meta-Analysis.
Combines immunocompetent and immunosuppressed
We investigated the effectiveness of nicotinamide, the active form of vitamin B3, in reducing skin cancers, particularly non-melanoma skin cancers (NMSCs). Our exploration included a systematic review of available literature, analyzing data from studies that assessed the potential benefits of oral nicotinamide among high-risk patients, including those with compromised immune systems.
After sifting through 225 studies, we found only four met our criteria for inclusion. The results were clear: there was no significant association between nicotinamide intake and a reduced risk of squamous cell carcinoma (SCC) or basal cell carcinoma (BCC). The statistics showed a rate ratio for SCC at 0.81 and for BCC at 0.88, which indicates no substantial benefit.
Although adverse effects from nicotinamide treatment were rare and manageable, the evidence points towards an insufficient impact of oral nicotinamide therapy on reducing keratinocyte cancers. It’s important to communicate that, while our findings are thorough, they highlight the need for more research. Overall, the use of dietary niacin intake also showed only a potential benefit related to SCC, but no effect on BCC or melanoma.
After sifting through 225 studies, we found only four met our criteria for inclusion. The results were clear: there was no significant association between nicotinamide intake and a reduced risk of squamous cell carcinoma (SCC) or basal cell carcinoma (BCC). The statistics showed a rate ratio for SCC at 0.81 and for BCC at 0.88, which indicates no substantial benefit.
Although adverse effects from nicotinamide treatment were rare and manageable, the evidence points towards an insufficient impact of oral nicotinamide therapy on reducing keratinocyte cancers. It’s important to communicate that, while our findings are thorough, they highlight the need for more research. Overall, the use of dietary niacin intake also showed only a potential benefit related to SCC, but no effect on BCC or melanoma.
Read More
Most Useful Reviews
8.8
Reduced recurrence
I started taking this vitamin because of an Australian study indicating it reduces the recurrence of skin cancer. It's worth checking out niacinamide on Wikipedia regarding its uses in medicine related to skin cancer.
Read More
9.5
Preventing recurrence
My dermatologist suggested that I take these daily to prevent a recurrence of skin cancer. I have now gone about four years without it happening!
Read More
9
Acne cleared
I absolutely adore this niacinamide! I had severe bacne, and after my dermatologist recommended it to help prevent common skin cancers, my back cleared up significantly in just three weeks. My facial skin has improved as well, eliminating painful cystic acne. I now subscribe to it, as I noticed acne returning when I ran out. I appreciate any assistance in preventing skin cancer as I have fair skin.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Ineffective
Based on 1 Research
3
- All Researches
3
Nicotinamide shows limited effectiveness
The Role of Nicotinamide as Chemo-Preventive Agent in NMSCs: A Systematic Review and Meta-Analysis.
Combines immunocompetent and immunosuppressed
We investigated the effectiveness of nicotinamide, the active form of vitamin B3, in reducing skin cancers, particularly non-melanoma skin cancers (NMSCs). Our exploration included a systematic review of available literature, analyzing data from studies that assessed the potential benefits of oral nicotinamide among high-risk patients, including those with compromised immune systems.
After sifting through 225 studies, we found only four met our criteria for inclusion. The results were clear: there was no significant association between nicotinamide intake and a reduced risk of squamous cell carcinoma (SCC) or basal cell carcinoma (BCC). The statistics showed a rate ratio for SCC at 0.81 and for BCC at 0.88, which indicates no substantial benefit.
Although adverse effects from nicotinamide treatment were rare and manageable, the evidence points towards an insufficient impact of oral nicotinamide therapy on reducing keratinocyte cancers. It’s important to communicate that, while our findings are thorough, they highlight the need for more research. Overall, the use of dietary niacin intake also showed only a potential benefit related to SCC, but no effect on BCC or melanoma.
After sifting through 225 studies, we found only four met our criteria for inclusion. The results were clear: there was no significant association between nicotinamide intake and a reduced risk of squamous cell carcinoma (SCC) or basal cell carcinoma (BCC). The statistics showed a rate ratio for SCC at 0.81 and for BCC at 0.88, which indicates no substantial benefit.
Although adverse effects from nicotinamide treatment were rare and manageable, the evidence points towards an insufficient impact of oral nicotinamide therapy on reducing keratinocyte cancers. It’s important to communicate that, while our findings are thorough, they highlight the need for more research. Overall, the use of dietary niacin intake also showed only a potential benefit related to SCC, but no effect on BCC or melanoma.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
8.8
Reduced recurrence
I started taking this vitamin because of an Australian study indicating it reduces the recurrence of skin cancer. It's worth checking out niacinamide on Wikipedia regarding its uses in medicine related to skin cancer.
9.5
Preventing recurrence
My dermatologist suggested that I take these daily to prevent a recurrence of skin cancer. I have now gone about four years without it happening!
9
Acne cleared
I absolutely adore this niacinamide! I had severe bacne, and after my dermatologist recommended it to help prevent common skin cancers, my back cleared up significantly in just three weeks. My facial skin has improved as well, eliminating painful cystic acne. I now subscribe to it, as I noticed acne returning when I ran out. I appreciate any assistance in preventing skin cancer as I have fair skin.
Read More
9
Discourages lesions
This product discourages the formation of squamous cell skin cancer, which can result from sun exposure. I take one tablet twice daily.
