Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Good
Based on 16 Reviews
8.8
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Iron (as Dried Ferrous Sulfate)
45 mg
250%
Top Medical Research Studies
9
We evaluated how switching to ferric citrate hydrate (FCH) impacts nausea in women with iron deficiency anemia (IDA) who struggled with oral iron. In a multicenter study of 30 patients, those on FCH experienced significant improvements. Nausea scores dropped from 5.7 to 1.7, and the overall incidence of nausea decreased notably. Also, 80% reported better experiences compared to previous treatments.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Read More
9
We conducted a study to examine the effectiveness of a specific iron supplement, emulsified microsomal ferric pyrophosphate (EMFP), in treating iron deficiency anemia among pregnant women. Our focus was not only on improving hemoglobin levels but also on alleviating related symptoms, including nausea.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Read More
7
We explored the effects of daily versus three times weekly (TIW) oral iron supplementation on nausea in NCAA Division 1 female athletes. The study involved 33 athletes who were either in track and field or soccer. Participants were given either daily doses or TIW doses of ferrous bisglycinate over eight weeks.
Both groups showed an increase in serum ferritin levels, which is a marker of iron stores. However, the TIW regimen resulted in a smaller increase of about 5.17 μg/L, compared to an increase of 12.88 μg/L with the daily regimen. Notably, those taking daily supplements experienced significantly more nausea and constipation than those on the TIW schedule.
While the daily regimen may boost iron levels more effectively, it can come at the cost of increased gastrointestinal discomfort. Meanwhile, the TIW regimen offers a gentler option with fewer side effects, positioning it as a viable alternative for athletes concerned about nausea.
Both groups showed an increase in serum ferritin levels, which is a marker of iron stores. However, the TIW regimen resulted in a smaller increase of about 5.17 μg/L, compared to an increase of 12.88 μg/L with the daily regimen. Notably, those taking daily supplements experienced significantly more nausea and constipation than those on the TIW schedule.
While the daily regimen may boost iron levels more effectively, it can come at the cost of increased gastrointestinal discomfort. Meanwhile, the TIW regimen offers a gentler option with fewer side effects, positioning it as a viable alternative for athletes concerned about nausea.
Read More
Most Useful Reviews
9
No dizziness, nausea
8 people found this helpful
I bought the "slow-release iron, 60 tablets" for my sister. It's an excellent product; I've not encountered such strong dietary supplements in ages. This inexpensive 21st Century brand did not disappoint – no dizziness or nausea at all! I have a new appreciation for this company. I will continue using this slow-release iron supplement.
Read More
9
No ill side effects
4 people found this helpful
Must have if you need iron. Taking iron that was prescribed was horrible and even led to vomiting. This iron is far superior. My levels are back up and I experience no adverse side effects. Goodbye nausea.
Read More
10
Great iron supplement
2 people found this helpful
Premium product! I'm using it before bed on a full stomach and have seen great results! There's no nausea or upset tummy, and my gut feels fine with this iron. It’s truly a fantastic option!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
- All Researches
9
We conducted a study to examine the effectiveness of a specific iron supplement, emulsified microsomal ferric pyrophosphate (EMFP), in treating iron deficiency anemia among pregnant women. Our focus was not only on improving hemoglobin levels but also on alleviating related symptoms, including nausea.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Read More
9
We evaluated how switching to ferric citrate hydrate (FCH) impacts nausea in women with iron deficiency anemia (IDA) who struggled with oral iron. In a multicenter study of 30 patients, those on FCH experienced significant improvements. Nausea scores dropped from 5.7 to 1.7, and the overall incidence of nausea decreased notably. Also, 80% reported better experiences compared to previous treatments.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Read More
7
We explored the effects of daily versus three times weekly (TIW) oral iron supplementation on nausea in NCAA Division 1 female athletes. The study involved 33 athletes who were either in track and field or soccer. Participants were given either daily doses or TIW doses of ferrous bisglycinate over eight weeks.
Both groups showed an increase in serum ferritin levels, which is a marker of iron stores. However, the TIW regimen resulted in a smaller increase of about 5.17 μg/L, compared to an increase of 12.88 μg/L with the daily regimen. Notably, those taking daily supplements experienced significantly more nausea and constipation than those on the TIW schedule.
While the daily regimen may boost iron levels more effectively, it can come at the cost of increased gastrointestinal discomfort. Meanwhile, the TIW regimen offers a gentler option with fewer side effects, positioning it as a viable alternative for athletes concerned about nausea.
Both groups showed an increase in serum ferritin levels, which is a marker of iron stores. However, the TIW regimen resulted in a smaller increase of about 5.17 μg/L, compared to an increase of 12.88 μg/L with the daily regimen. Notably, those taking daily supplements experienced significantly more nausea and constipation than those on the TIW schedule.
While the daily regimen may boost iron levels more effectively, it can come at the cost of increased gastrointestinal discomfort. Meanwhile, the TIW regimen offers a gentler option with fewer side effects, positioning it as a viable alternative for athletes concerned about nausea.
Read More
7
Ferric carboxymaltose reduces nausea
This randomized controlled trial explored how low-dose ferric carboxymaltose (FCM) affects hemoglobin levels and nausea in postpartum East Asian women. Participants received either an intravenous FCM infusion or oral iron for four weeks.
We found that while FCM significantly increased hemoglobin levels after two weeks, both treatments showed no significant difference in final hemoglobin results after four weeks.
Notably, the FCM group experienced fewer gastrointestinal side effects, including nausea, suggesting it may be a more comfortable option for new mothers.
We found that while FCM significantly increased hemoglobin levels after two weeks, both treatments showed no significant difference in final hemoglobin results after four weeks.
Notably, the FCM group experienced fewer gastrointestinal side effects, including nausea, suggesting it may be a more comfortable option for new mothers.
Read More
User Reviews
USERS' SCORE
Good
Based on 16 Reviews
8.8
- All Reviews
- Positive Reviews
- Negative Reviews
9
No dizziness, nausea
8 people found this helpful
I bought the "slow-release iron, 60 tablets" for my sister. It's an excellent product; I've not encountered such strong dietary supplements in ages. This inexpensive 21st Century brand did not disappoint – no dizziness or nausea at all! I have a new appreciation for this company. I will continue using this slow-release iron supplement.
Read More
9
No ill side effects
4 people found this helpful
Must have if you need iron. Taking iron that was prescribed was horrible and even led to vomiting. This iron is far superior. My levels are back up and I experience no adverse side effects. Goodbye nausea.
Read More
10
Great iron supplement
2 people found this helpful
Premium product! I'm using it before bed on a full stomach and have seen great results! There's no nausea or upset tummy, and my gut feels fine with this iron. It’s truly a fantastic option!
Read More
9
No nausea, easy pills
1 people found this helpful
I hope this helps—this iron supplement is gentle on my stomach. Unlike other iron pills, I didn't feel any nausea. The small, dark red pills are easy to swallow.
Read More
9
No nausea or constipation
1 people found this helpful
Cheap and it works! I am on iron essentially for life. I have tried numerous iron brands and this one is my favourite. There are no iron burps or aftertaste, no constipation, and I feel energetic quite quickly. Importantly, there are no dark stools or nausea, plus it’s quite affordable!
Read More
Frequently Asked Questions
10
Great iron supplement
2 people found this helpful
Premium product! I'm using it before bed on a full stomach and have seen great results! There's no nausea or upset tummy, and my gut feels fine with this iron. It’s truly a fantastic option!
9
Steady improvement
I’ve been deficient in iron since becoming pregnant and have taken various supplements. This is easy to drink without the nausea side effects that are often prescribed. My blood tests are improving steadily.
9
Gentle on stomach
It’s gentle on my stomach, with no nausea like other iron supplements. I’ve noticed improved energy and less fatigue since taking it. Highly recommend for those with iron deficiency!
9
Gentle product
Great product! It can be taken at any time without causing nausea, being gentle on your stomach compared to other iron supplements I’ve tried.
10
Dizziness alleviated
Loved it! I no longer feel dizzy and my blood test results are perfect! No nausea at all; the ingredients are great and the quality is superb.
9
No dizziness, nausea
8 people found this helpful
I bought the "slow-release iron, 60 tablets" for my sister. It's an excellent product; I've not encountered such strong dietary supplements in ages. This inexpensive 21st Century brand did not disappoint – no dizziness or nausea at all! I have a new appreciation for this company. I will continue using this slow-release iron supplement.
9
No nausea, easy pills
1 people found this helpful
I hope this helps—this iron supplement is gentle on my stomach. Unlike other iron pills, I didn't feel any nausea. The small, dark red pills are easy to swallow.
9
No nausea
No uneasy stomach. It worked well to increase my iron levels without the nausea that non-slow release pills can sometimes cause. Fantastic!
9
We conducted a study to examine the effectiveness of a specific iron supplement, emulsified microsomal ferric pyrophosphate (EMFP), in treating iron deficiency anemia among pregnant women. Our focus was not only on improving hemoglobin levels but also on alleviating related symptoms, including nausea.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
Within 30 days of starting treatment with EMFP, we observed significant increases in hemoglobin levels, alongside marked improvements in serum ferritin and iron levels. As nausea is a common complaint among pregnant women, we noted a decrease in various symptoms, including nausea, breathlessness, and dizziness, which contributed to a better quality of life for the participants.
Notably, treatment compliance was remarkably high at 99.5%, indicating that the participants were committed to managing their anemia effectively. Importantly, we did not encounter any severe side effects related to the treatment, suggesting a favorable safety profile.
Overall, our findings support the idea that iron treatment can help alleviate nausea and other discomforts related to iron deficiency anemia in pregnancy, positively impacting both mother and baby.
9
We evaluated how switching to ferric citrate hydrate (FCH) impacts nausea in women with iron deficiency anemia (IDA) who struggled with oral iron. In a multicenter study of 30 patients, those on FCH experienced significant improvements. Nausea scores dropped from 5.7 to 1.7, and the overall incidence of nausea decreased notably. Also, 80% reported better experiences compared to previous treatments.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
7
We explored the effects of daily versus three times weekly (TIW) oral iron supplementation on nausea in NCAA Division 1 female athletes. The study involved 33 athletes who were either in track and field or soccer. Participants were given either daily doses or TIW doses of ferrous bisglycinate over eight weeks.
Both groups showed an increase in serum ferritin levels, which is a marker of iron stores. However, the TIW regimen resulted in a smaller increase of about 5.17 μg/L, compared to an increase of 12.88 μg/L with the daily regimen. Notably, those taking daily supplements experienced significantly more nausea and constipation than those on the TIW schedule.
While the daily regimen may boost iron levels more effectively, it can come at the cost of increased gastrointestinal discomfort. Meanwhile, the TIW regimen offers a gentler option with fewer side effects, positioning it as a viable alternative for athletes concerned about nausea.
Both groups showed an increase in serum ferritin levels, which is a marker of iron stores. However, the TIW regimen resulted in a smaller increase of about 5.17 μg/L, compared to an increase of 12.88 μg/L with the daily regimen. Notably, those taking daily supplements experienced significantly more nausea and constipation than those on the TIW schedule.
While the daily regimen may boost iron levels more effectively, it can come at the cost of increased gastrointestinal discomfort. Meanwhile, the TIW regimen offers a gentler option with fewer side effects, positioning it as a viable alternative for athletes concerned about nausea.
References
- Srivastav A, Kshirsagar S, Adhav T, Ganu G, Shah A. Efficacy and Safety of Microsomal Ferric Pyrophosphate Supplement for Iron Deficiency Anemia in Pregnancy. Cureus. 2024;16:e57108. doi:10.7759/cureus.57108
- Schulte J, Peterson K, Thomsen T, Lentz S, Hall M, et al. Daily versus three times weekly dosing for treatment of iron deficiency nonanemia in NCAA Division 1 female athletes. PM R. 2024;16:316. doi:10.1002/pmrj.13172
- Nagao T, Takahashi K, Takahashi S, Yokomizo R, Samura O, et al. Low-dose ferric carboxymaltose vs. oral iron for improving hemoglobin levels in postpartum East Asian women: A randomized controlled trial. PLoS One. 2025;20:e0319795. doi:10.1371/journal.pone.0319795
- Wada-Hiraike O, Maruyama A, Mitobe Y, Iriyama T, Mori-Uchino M, et al. A Multicenter Single-Arm Study of Switching to Ferric Citrate Hydrate for Iron Deficiency Anemia in Patients Intolerant to Oral Iron: RIO-SWITCH. Adv Ther. 2025. doi:10.1007/s12325-025-03123-9
