Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.7
Supplement Facts
Serving Size: 2 Veggie Capsules
Amount Per Serving
%DV
Quercetin (as Quercetin Dihydrate)(Dimorphandra mollis) (seed pod)
500 mg
â€
Bromelain (from pineapple stem)(2400 GDU/gram)
250 mg
â€
Top Medical Research Studies
9
Quercetin reduces sinus inflammation
This study explored how quercetin may help reduce inflammation associated with sinusitis using a rat model. We observed that introducing lipopolysaccharides (LPS) caused significant inflammation in nasal and sinus areas, as well as in the lungs and brain.
When we administered quercetin after the LPS treatment, it notably decreased inflammatory markers like TNF-α and IL-6. The results indicated reduced inflammation in nasal and lung tissues, showcasing quercetin's potential benefits. However, while there were encouraging findings, its effects on brain inflammation were more limited.
When we administered quercetin after the LPS treatment, it notably decreased inflammatory markers like TNF-α and IL-6. The results indicated reduced inflammation in nasal and lung tissues, showcasing quercetin's potential benefits. However, while there were encouraging findings, its effects on brain inflammation were more limited.
Read More
8
Quercetin enhances mucus transport
We explored how quercetin might help sinusitis by boosting chloride secretion and improving ciliary beat frequency in cultured sinonasal cells. In our analysis, this compound showed notable ability to enhance these functions, suggesting it could promote better mucus clearance from the sinuses.
The study involved primary cultures of human and murine sinonasal epithelial cells and demonstrated quercetin's effectiveness in increasing chloride transport. This implies potential therapeutic benefits for individuals suffering from chronic rhinosinusitis.
The study involved primary cultures of human and murine sinonasal epithelial cells and demonstrated quercetin's effectiveness in increasing chloride transport. This implies potential therapeutic benefits for individuals suffering from chronic rhinosinusitis.
Read More
7
We explored how quercetin affects sinusitis by examining its impact on human mast cells. Specifically, we focused on the expression of inflammatory cytokines after stimulating the cells.
Quercetin showed promise by reducing the gene expression and production of key inflammatory signals like TNF-alpha and IL-6. It did this by dampening the activation of NF-kappaB and p38 MAPK pathways, both crucial for inflammation.
This suggests that quercetin may be beneficial for managing conditions like sinusitis linked to mast cell activity.
Quercetin showed promise by reducing the gene expression and production of key inflammatory signals like TNF-alpha and IL-6. It did this by dampening the activation of NF-kappaB and p38 MAPK pathways, both crucial for inflammation.
This suggests that quercetin may be beneficial for managing conditions like sinusitis linked to mast cell activity.
Read More
Most Useful Reviews
10
No more sinusitis
121 people found this helpful
I developed chronic sinusitis due to Eustachian tube dysfunction linked to allergies. After frequent doctor visits and antibiotics, I sought natural alternatives. Since trying this product, I haven't experienced sinusitis or clogged ears, and it effectively clears my nose when I feel symptoms arising. I'm hopeful it will continue to work during pollen season as it did through winter. However, be cautious about dosage, especially with bromelain.
Read More
9
Good for sinus issues
7 people found this helpful
This product worked well during a recent bout of sinusitis over the Christmas holiday when I was quite miserable. It has now become my go-to remedy for sinus-related problems.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
- All Researches
9
Quercetin reduces sinus inflammation
This study explored how quercetin may help reduce inflammation associated with sinusitis using a rat model. We observed that introducing lipopolysaccharides (LPS) caused significant inflammation in nasal and sinus areas, as well as in the lungs and brain.
When we administered quercetin after the LPS treatment, it notably decreased inflammatory markers like TNF-α and IL-6. The results indicated reduced inflammation in nasal and lung tissues, showcasing quercetin's potential benefits. However, while there were encouraging findings, its effects on brain inflammation were more limited.
When we administered quercetin after the LPS treatment, it notably decreased inflammatory markers like TNF-α and IL-6. The results indicated reduced inflammation in nasal and lung tissues, showcasing quercetin's potential benefits. However, while there were encouraging findings, its effects on brain inflammation were more limited.
Read More
8
Quercetin enhances mucus transport
We explored how quercetin might help sinusitis by boosting chloride secretion and improving ciliary beat frequency in cultured sinonasal cells. In our analysis, this compound showed notable ability to enhance these functions, suggesting it could promote better mucus clearance from the sinuses.
The study involved primary cultures of human and murine sinonasal epithelial cells and demonstrated quercetin's effectiveness in increasing chloride transport. This implies potential therapeutic benefits for individuals suffering from chronic rhinosinusitis.
The study involved primary cultures of human and murine sinonasal epithelial cells and demonstrated quercetin's effectiveness in increasing chloride transport. This implies potential therapeutic benefits for individuals suffering from chronic rhinosinusitis.
Read More
7
We explored how quercetin affects sinusitis by examining its impact on human mast cells. Specifically, we focused on the expression of inflammatory cytokines after stimulating the cells.
Quercetin showed promise by reducing the gene expression and production of key inflammatory signals like TNF-alpha and IL-6. It did this by dampening the activation of NF-kappaB and p38 MAPK pathways, both crucial for inflammation.
This suggests that quercetin may be beneficial for managing conditions like sinusitis linked to mast cell activity.
Quercetin showed promise by reducing the gene expression and production of key inflammatory signals like TNF-alpha and IL-6. It did this by dampening the activation of NF-kappaB and p38 MAPK pathways, both crucial for inflammation.
This suggests that quercetin may be beneficial for managing conditions like sinusitis linked to mast cell activity.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
10
No more sinusitis
121 people found this helpful
I developed chronic sinusitis due to Eustachian tube dysfunction linked to allergies. After frequent doctor visits and antibiotics, I sought natural alternatives. Since trying this product, I haven't experienced sinusitis or clogged ears, and it effectively clears my nose when I feel symptoms arising. I'm hopeful it will continue to work during pollen season as it did through winter. However, be cautious about dosage, especially with bromelain.
Read More
9
Good for sinus issues
7 people found this helpful
This product worked well during a recent bout of sinusitis over the Christmas holiday when I was quite miserable. It has now become my go-to remedy for sinus-related problems.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Tiboc-Schnell CN, Filip GA, Man SC, Decea N, Moldovan R, et al. Quercetin attenuates naso-sinusal inflammation and inflammatory response in lungs and brain on an experimental model of acute rhinosinusitis in rats. J Physiol Pharmacol. 2020;71. 10.26402/jpp.2020.4.03
- Zhang S, Smith N, Schuster D, Azbell C, Sorscher EJ, et al. Quercetin increases cystic fibrosis transmembrane conductance regulator-mediated chloride transport and ciliary beat frequency: therapeutic implications for chronic rhinosinusitis. Am J Rhinol Allergy. 2011;25:307. 10.2500/ajra.2011.25.3643
- Min YD, Choi CH, Bark H, Son HY, Park HH, et al. Quercetin inhibits expression of inflammatory cytokines through attenuation of NF-kappaB and p38 MAPK in HMC-1 human mast cell line. Inflamm Res. 2007;56:210.
