Last update
5/3/2026
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Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.3
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Acetyl-L-Carnitine (from 1,250 mg Acetyl-L-Carnitine HCl)
1 g (1,000 mg)
**
Top Medical Research Studies
7
We examined how acetyl-L-carnitine affects stress responses in rats exposed to cold swimming. Over ten days, we compared the effects of two stress types and found that cold-swimming significantly increased beta-endorphin levels in both the pituitary and plasma. Notably, acetyl-L-carnitine treatment appeared to offset these changes induced by cold stress. However, it’s essential to highlight that while there were improvements observed with acetyl-L-carnitine, the overall effectiveness for treating cold-related symptoms remains uncertain based on these findings.
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8
ALC maintains testosterone under stress
This study explored the impact of stress and acetyl-l-carnitine (ALC) on hormone levels in male rats. We found that chronic swimming stress decreased reproductive hormones and testosterone levels.
However, ALC treatment appeared to counteract this decline, helping maintain testosterone during stress. This suggests ALC may play a protective role against stress-induced hormonal disruptions.
In contrast, ether stress did not show the same effects on testosterone, highlighting the unique responses to different stressors.
However, ALC treatment appeared to counteract this decline, helping maintain testosterone during stress. This suggests ALC may play a protective role against stress-induced hormonal disruptions.
In contrast, ether stress did not show the same effects on testosterone, highlighting the unique responses to different stressors.
Read More
Most Useful Reviews
3
Weight loss with cold
8 people found this helpful
For the first time during menopause, I lost weight. Initially, taking carnitine with alpha lipoic acid on an empty stomach didn’t work, but after switching to other vitamins with dinner, I lost 5kg in a month! I did have a mild cold during this time, but I was pleasantly surprised by the weight drop.
Read More
7
Effective for weight loss
5 people found this helpful
Stay warm in winter and lose weight by sweating in summer! When I took acetyl carnitine in winter, I didn't feel cold at night. In summer, I noticed a significant increase in sweating. It seems effective for weight loss. I no longer feel drowsy upon waking; I feel truly alert.
Read More
6
Improved cold tolerance
5 people found this helpful
I believe there is an effect! I started taking it and found it easier to sweat. Last year, at my workplace in cold weather, I felt chilly even in midsummer. This year, however, it feels just right. I've even asked my colleagues, "Have you been feeling cold recently?" I plan to continue since my body feels slightly tighter.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
- All Researches
8
ALC maintains testosterone under stress
This study explored the impact of stress and acetyl-l-carnitine (ALC) on hormone levels in male rats. We found that chronic swimming stress decreased reproductive hormones and testosterone levels.
However, ALC treatment appeared to counteract this decline, helping maintain testosterone during stress. This suggests ALC may play a protective role against stress-induced hormonal disruptions.
In contrast, ether stress did not show the same effects on testosterone, highlighting the unique responses to different stressors.
However, ALC treatment appeared to counteract this decline, helping maintain testosterone during stress. This suggests ALC may play a protective role against stress-induced hormonal disruptions.
In contrast, ether stress did not show the same effects on testosterone, highlighting the unique responses to different stressors.
Read More
7
We examined how acetyl-L-carnitine affects stress responses in rats exposed to cold swimming. Over ten days, we compared the effects of two stress types and found that cold-swimming significantly increased beta-endorphin levels in both the pituitary and plasma. Notably, acetyl-L-carnitine treatment appeared to offset these changes induced by cold stress. However, it’s essential to highlight that while there were improvements observed with acetyl-L-carnitine, the overall effectiveness for treating cold-related symptoms remains uncertain based on these findings.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.3
- All Reviews
- Positive Reviews
- Negative Reviews
3
Weight loss with cold
8 people found this helpful
For the first time during menopause, I lost weight. Initially, taking carnitine with alpha lipoic acid on an empty stomach didn’t work, but after switching to other vitamins with dinner, I lost 5kg in a month! I did have a mild cold during this time, but I was pleasantly surprised by the weight drop.
Read More
7
Effective for weight loss
5 people found this helpful
Stay warm in winter and lose weight by sweating in summer! When I took acetyl carnitine in winter, I didn't feel cold at night. In summer, I noticed a significant increase in sweating. It seems effective for weight loss. I no longer feel drowsy upon waking; I feel truly alert.
Read More
6
Improved cold tolerance
5 people found this helpful
I believe there is an effect! I started taking it and found it easier to sweat. Last year, at my workplace in cold weather, I felt chilly even in midsummer. This year, however, it feels just right. I've even asked my colleagues, "Have you been feeling cold recently?" I plan to continue since my body feels slightly tighter.
Read More
5
Increased sweating
4 people found this helpful
I trusted Now Foods and purchased it. Taking it before exercise makes me sweat much more than when I don’t. Even in the morning, I feel warm at night. Although it’s cold, I sense that the coldness has diminished since I started taking it. I wonder if I’ll sweat even more in summer.
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6
Warmed body and hands
3 people found this helpful
I felt warm about 30 minutes after drinking it. My metabolism isn’t great; my hands and feet get cold. Drinking it prior to exercising seemed effective, heating my body quicker than usual. However, I struggled to swallow it without water, as the sour powder is quite intense.
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Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Bidzinska B, Petraglia F, Angioni S, Genazzani AD, Criscuolo M, et al. Effect of different chronic intermittent stressors and acetyl-l-carnitine on hypothalamic beta-endorphin and GnRH and on plasma testosterone levels in male rats. Neuroendocrinology. 1993;57:985. PubMed
- Bidzinska B, Petraglia F, Angioni S, Genazzani AD, Criscuolo M, et al. Acetyl-L-carnitine effect on pituitary and plasma beta-endorphin responsiveness to different chronic intermittent stressors. J Neuroendocrinol. 1993;5:151. PubMed
