This study investigated how Silymarin affects the growth of insulin-producing cells in a model of partial pancreas removal in rats.
We treated 72 Wistar rats, half of which were given Silymarin daily. The results were clear: the Silymarin-treated rats showed significant increases in both the Pdx1 gene, which is vital for pancreatic health, and insulin production.
Additionally, their β-cell proliferation improved, leading to better blood sugar control. However, the specific effects on pancreatitis were not explored in this study.
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7
Silymarin protects tissues without lowering glucose
Silymarin Attenuates Hepatic and Pancreatic Redox Imbalance Independent of Glycemic Regulation in the Alloxan-induced Diabetic Rat Model.
We set out to see how silymarin (SMN) could help rats suffering from type 1 diabetes, particularly focusing on the liver and pancreas. In this study, we treated diabetic rats with SMN over 30 days while comparing them to control groups.
Although we noticed that silymarin significantly reduced signs of protein damage in the liver and pancreas, as well as improved renal function, it didn’t help lower blood glucose levels or enhance pancreatic beta-cell function. Overall, this suggests that while silymarin shows promise in protecting pancreatic and liver health, it doesn’t affect blood sugar levels in diabetic conditions.
Read More
Most Useful Reviews
9
Supports digestion
I find this supplement essential and take it daily after my pancreatitis attack and gallstones treatment. It's been incredibly helpful.
Read More
9
Life-saving remedy
This excellent product supports liver function and the whole digestive system. The mega dosage of milk thistle is invaluable for my chronic pancreatitis condition. I highly recommend it; it has been like a salvation for me.
This study investigated how Silymarin affects the growth of insulin-producing cells in a model of partial pancreas removal in rats.
We treated 72 Wistar rats, half of which were given Silymarin daily. The results were clear: the Silymarin-treated rats showed significant increases in both the Pdx1 gene, which is vital for pancreatic health, and insulin production.
Additionally, their β-cell proliferation improved, leading to better blood sugar control. However, the specific effects on pancreatitis were not explored in this study.
Read More
7
Silymarin protects tissues without lowering glucose
Silymarin Attenuates Hepatic and Pancreatic Redox Imbalance Independent of Glycemic Regulation in the Alloxan-induced Diabetic Rat Model.
We set out to see how silymarin (SMN) could help rats suffering from type 1 diabetes, particularly focusing on the liver and pancreas. In this study, we treated diabetic rats with SMN over 30 days while comparing them to control groups.
Although we noticed that silymarin significantly reduced signs of protein damage in the liver and pancreas, as well as improved renal function, it didn’t help lower blood glucose levels or enhance pancreatic beta-cell function. Overall, this suggests that while silymarin shows promise in protecting pancreatic and liver health, it doesn’t affect blood sugar levels in diabetic conditions.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
All Reviews
Positive Reviews
Negative Reviews
9
Supports digestion
I find this supplement essential and take it daily after my pancreatitis attack and gallstones treatment. It's been incredibly helpful.
Read More
9
Life-saving remedy
This excellent product supports liver function and the whole digestive system. The mega dosage of milk thistle is invaluable for my chronic pancreatitis condition. I highly recommend it; it has been like a salvation for me.
Read More
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References
Miranda LMO, Agostini LDC, Lima WG, Camini FC, Costa DC. Silymarin Attenuates Hepatic and Pancreatic Redox Imbalance Independent of Glycemic Regulation in the Alloxan-induced Diabetic Rat Model. Biomed Environ Sci. 2020;33:690. 10.3967/bes2020.090
Soto C, Raya L, Juárez J, Pérez J, González I. Effect of Silymarin in Pdx-1 expression and the proliferation of pancreatic β-cells in a pancreatectomy model. Phytomedicine. 2014;21:233. 10.1016/j.phymed.2013.09.008