Last update
4/11/2026
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9.5
USERS' SCORE
Good
Based on 8 Reviews
8.1
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Pantothenic Acid (Vitamin B-5) (From Calcium Pantothenate)
500 mg
10,000%
Calcium (From Calcium Pantothenate)
45 mg
3%
Top Medical Research Studies
9.5
We investigated how calcium, specifically in the form of two-dimensional layered calcium disilicide nanoparticles (CSNs), can play a role in treating rheumatoid arthritis (RA). Unlike typical RA treatments that primarily focus on reducing inflammation, we observed that CSNs have multifunctional properties that can address the inflammatory aspect while also promoting bone health and repair.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
Read More
Most Useful Reviews
9
Skin condition enhanced
13 people found this helpful
The vitamin I ordered on my doctor's advice is crucial for my treatment. After nearly a month, I saw my skin transform from dry and itchy to smooth and velvety within a week. This vitamin has become my best ally and I plan to continue taking it with short breaks.
Read More
7.5
Autoimmune condition managed
5 people found this helpful
For many years, I've been taking NOW B5 without any stomach issues, and it has significantly helped keep my autoimmune condition in check when combined with NOW Niacinamide (B3) as recommended by a Naturopath. I take 2 x B5 and 1 Niac twice daily. Additionally, B5 aids in calming my nerves.
Read More
9
Skin enhancement noted
3 people found this helpful
I have been using this product for a few weeks to improve my skin condition (acne), and I can already see a substantial improvement. Thank you for this excellent product; I will be ordering it again soon.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9.5
- All Researches
9.5
We investigated how calcium, specifically in the form of two-dimensional layered calcium disilicide nanoparticles (CSNs), can play a role in treating rheumatoid arthritis (RA). Unlike typical RA treatments that primarily focus on reducing inflammation, we observed that CSNs have multifunctional properties that can address the inflammatory aspect while also promoting bone health and repair.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Skin condition enhanced
13 people found this helpful
The vitamin I ordered on my doctor's advice is crucial for my treatment. After nearly a month, I saw my skin transform from dry and itchy to smooth and velvety within a week. This vitamin has become my best ally and I plan to continue taking it with short breaks.
Read More
7.5
Autoimmune condition managed
5 people found this helpful
For many years, I've been taking NOW B5 without any stomach issues, and it has significantly helped keep my autoimmune condition in check when combined with NOW Niacinamide (B3) as recommended by a Naturopath. I take 2 x B5 and 1 Niac twice daily. Additionally, B5 aids in calming my nerves.
Read More
9
Skin enhancement noted
3 people found this helpful
I have been using this product for a few weeks to improve my skin condition (acne), and I can already see a substantial improvement. Thank you for this excellent product; I will be ordering it again soon.
Read More
7.5
Symptoms alleviated
2 people found this helpful
The quality and quantity of the ingredients are excellent. I have been experiencing issues due to poor eating habits, which resulted in skin problems. While the product alleviated my symptoms, they did not completely disappear, and I’ve committed to a healthier lifestyle for better results.
Read More
7.5
Skin and hair growth
1 people found this helpful
I am about to place my second order after taking these capsules for less than a year. I've noticed improvements not only in my skin but also slight hair and nail growth. For beginners, I recommend taking one capsule per day for a week before increasing the dosage. In my case, taking 4 capsules has proven beneficial.
Read More
Frequently Asked Questions
7.5
Nails and hair thrive
1 people found this helpful
I had a severe vitamin deficiency due to my autoimmune disorder, which affected my hair and nails significantly. A friend introduced this supplement to me, and I've since realised my nails are much stronger and growing longer, as well as my hair thickening remarkably. I wasn't aware that this supplement contained B5, which is also in many hair products. I eat healthily, but this product quickly delivered visible results.
7.5
Autoimmune condition managed
5 people found this helpful
For many years, I've been taking NOW B5 without any stomach issues, and it has significantly helped keep my autoimmune condition in check when combined with NOW Niacinamide (B3) as recommended by a Naturopath. I take 2 x B5 and 1 Niac twice daily. Additionally, B5 aids in calming my nerves.
7.5
Skin and hair growth
1 people found this helpful
I am about to place my second order after taking these capsules for less than a year. I've noticed improvements not only in my skin but also slight hair and nail growth. For beginners, I recommend taking one capsule per day for a week before increasing the dosage. In my case, taking 4 capsules has proven beneficial.
9.5
We investigated how calcium, specifically in the form of two-dimensional layered calcium disilicide nanoparticles (CSNs), can play a role in treating rheumatoid arthritis (RA). Unlike typical RA treatments that primarily focus on reducing inflammation, we observed that CSNs have multifunctional properties that can address the inflammatory aspect while also promoting bone health and repair.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
References
- Ji P, Qiu S, Huang J, Wang L, Wang Y, et al. Hydrolysis of 2D Nanosheets Reverses Rheumatoid Arthritis Through Anti-Inflammation and Osteogenesis. Adv Mater. 2025;37:e2415543. 10.1002/adma.202415543
