Last update
4/13/2026
Research Authors

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.9
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Pantothenic Acid (Vitamin B-5) (From Calcium Pantothenate)
500 mg
10,000%
Calcium (From Calcium Pantothenate)
45 mg
3%
📅 Last updated:

Top Medical Research Studies

7
Calcium spirulan may help cold sores
We investigated the potential of calcium spirulan, a compound derived from the microalga Spirulina platensis, to help prevent cold sores caused by the herpes simplex virus type 1 (HSV-1). In a thorough study, we assessed the effectiveness of this sulfated polysaccharide both in laboratory tests and through a practical trial involving people with recurring herpes labialis, also known as cold sores.

Our approach included examining how calcium spirulan affected the virus’s ability to attach to human skin cells. Using various experiments such as plaque reduction assays and analyzing viral proteins, we confirmed that calcium spirulan had significant inhibitory effects on HSV-1. In the practical trial, we compared the effects of topical calcium spirulan treatment against other commonly used antiviral medications among 198 participants, all of whom dealt with repeat cold sore outbreaks.

The results suggest that calcium spirulan could be a valuable option for topical treatment, offering new hope for those who suffer from cold sores. Additionally, our findings indicate that calcium spirulan may also show effectiveness against other herpesviruses. This points to the broader clinical implications of using natural compounds like calcium spirulan in managing viral infections.
Read More

Most Useful Reviews

7.5
Helps oily scalp
5 people found this helpful
Recommended for those with oily scalp and face. I'm concerned about my scalp being sore and my face being oily and prone to acne, but pantothenic acid alleviates these issues. I initially took four tablets nightly, but now I take two in the morning and evening. It's beneficial to adjust the amount according to your menstrual cycle and the season. The capsules are easy to swallow.
Read More
0
No improvement noted
1 people found this helpful
I want to improve my adult cold sore issue, but after three months of taking it, I haven't noticed any improvement.
Read More

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Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
  • All Researches
7
Calcium spirulan may help cold sores
We investigated the potential of calcium spirulan, a compound derived from the microalga Spirulina platensis, to help prevent cold sores caused by the herpes simplex virus type 1 (HSV-1). In a thorough study, we assessed the effectiveness of this sulfated polysaccharide both in laboratory tests and through a practical trial involving people with recurring herpes labialis, also known as cold sores.

Our approach included examining how calcium spirulan affected the virus’s ability to attach to human skin cells. Using various experiments such as plaque reduction assays and analyzing viral proteins, we confirmed that calcium spirulan had significant inhibitory effects on HSV-1. In the practical trial, we compared the effects of topical calcium spirulan treatment against other commonly used antiviral medications among 198 participants, all of whom dealt with repeat cold sore outbreaks.

The results suggest that calcium spirulan could be a valuable option for topical treatment, offering new hope for those who suffer from cold sores. Additionally, our findings indicate that calcium spirulan may also show effectiveness against other herpesviruses. This points to the broader clinical implications of using natural compounds like calcium spirulan in managing viral infections.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 2 Reviews
7.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Helps oily scalp
5 people found this helpful
Recommended for those with oily scalp and face. I'm concerned about my scalp being sore and my face being oily and prone to acne, but pantothenic acid alleviates these issues. I initially took four tablets nightly, but now I take two in the morning and evening. It's beneficial to adjust the amount according to your menstrual cycle and the season. The capsules are easy to swallow.
Read More
0
No improvement noted
1 people found this helpful
I want to improve my adult cold sore issue, but after three months of taking it, I haven't noticed any improvement.
Read More

Frequently Asked Questions

0
No improvement noted
1 people found this helpful
I want to improve my adult cold sore issue, but after three months of taking it, I haven't noticed any improvement.
7.5
Helps oily scalp
5 people found this helpful
Recommended for those with oily scalp and face. I'm concerned about my scalp being sore and my face being oily and prone to acne, but pantothenic acid alleviates these issues. I initially took four tablets nightly, but now I take two in the morning and evening. It's beneficial to adjust the amount according to your menstrual cycle and the season. The capsules are easy to swallow.
7
Calcium spirulan may help cold sores
We investigated the potential of calcium spirulan, a compound derived from the microalga Spirulina platensis, to help prevent cold sores caused by the herpes simplex virus type 1 (HSV-1). In a thorough study, we assessed the effectiveness of this sulfated polysaccharide both in laboratory tests and through a practical trial involving people with recurring herpes labialis, also known as cold sores.

Our approach included examining how calcium spirulan affected the virus’s ability to attach to human skin cells. Using various experiments such as plaque reduction assays and analyzing viral proteins, we confirmed that calcium spirulan had significant inhibitory effects on HSV-1. In the practical trial, we compared the effects of topical calcium spirulan treatment against other commonly used antiviral medications among 198 participants, all of whom dealt with repeat cold sore outbreaks.

The results suggest that calcium spirulan could be a valuable option for topical treatment, offering new hope for those who suffer from cold sores. Additionally, our findings indicate that calcium spirulan may also show effectiveness against other herpesviruses. This points to the broader clinical implications of using natural compounds like calcium spirulan in managing viral infections.

References

  1. Mader J, Gallo A, Schommartz T, Handke W, Nagel CH, et al. Calcium spirulan derived from Spirulina platensis inhibits herpes simplex virus 1 attachment to human keratinocytes and protects against herpes labialis. J Allergy Clin Immunol. 2016;137:197. 10.1016/j.jaci.2015.07.027
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