Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Moderately Good
Based on 13 Reviews
7.4
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Pantothenic Acid (Vitamin B-5) (From Calcium Pantothenate)
500 mg
10,000%
Calcium (From Calcium Pantothenate)
45 mg
3%
Top Medical Research Studies
9
We examined the effects of embelin, a compound derived from the dried berries of Embelia ribes, on cholesterol levels by focusing on its relationship with calcium in liver cells. Our analysis showed that embelin treatment aids in regulating cholesterol metabolism by influencing key proteins associated with cholesterol clearance.
The study highlighted how embelin can elevate calcium levels within the endoplasmic reticulum (ER), which is essential for proper cellular function. By increasing calcium, we observed a decrease in the activity of a protein known as PCSK9, which typically hinders the liver's ability to remove low-density lipoprotein (LDL) cholesterol from circulation.
By regulating the levels of SREBP2, another protein linked to cholesterol control, embelin ultimately enhances the liver's capacity to clear LDL from the bloodstream. This mechanism reveals that calcium plays an important role, particularly in how embelin mediates cholesterol levels through its effects on proteins involved in cholesterol metabolism.
Overall, the findings suggest that embelin may offer a natural avenue for improving cholesterol management, particularly in the context of cardiovascular health.
The study highlighted how embelin can elevate calcium levels within the endoplasmic reticulum (ER), which is essential for proper cellular function. By increasing calcium, we observed a decrease in the activity of a protein known as PCSK9, which typically hinders the liver's ability to remove low-density lipoprotein (LDL) cholesterol from circulation.
By regulating the levels of SREBP2, another protein linked to cholesterol control, embelin ultimately enhances the liver's capacity to clear LDL from the bloodstream. This mechanism reveals that calcium plays an important role, particularly in how embelin mediates cholesterol levels through its effects on proteins involved in cholesterol metabolism.
Overall, the findings suggest that embelin may offer a natural avenue for improving cholesterol management, particularly in the context of cardiovascular health.
Read More
Most Useful Reviews
7.5
Aids fat metabolism
7 people found this helpful
Aiding in fat metabolism and cholesterol management, I find this product effective. I take it with inositol after dinner and have noticed an increase in energy levels along with satisfactory results.
Read More
10
Maintains clear skin
3 people found this helpful
It helps control my breakouts and oily skin. I cleared my hormonal cystic acne in just a few months with a maintenance dose, and I’ve kept it clear for three years now. Highly recommended!
Read More
9
Effective for acne
1 people found this helpful
I purchased this for my son, as high doses of pantothenic acid are effective against acne, and it has really worked for him.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
We examined the effects of embelin, a compound derived from the dried berries of Embelia ribes, on cholesterol levels by focusing on its relationship with calcium in liver cells. Our analysis showed that embelin treatment aids in regulating cholesterol metabolism by influencing key proteins associated with cholesterol clearance.
The study highlighted how embelin can elevate calcium levels within the endoplasmic reticulum (ER), which is essential for proper cellular function. By increasing calcium, we observed a decrease in the activity of a protein known as PCSK9, which typically hinders the liver's ability to remove low-density lipoprotein (LDL) cholesterol from circulation.
By regulating the levels of SREBP2, another protein linked to cholesterol control, embelin ultimately enhances the liver's capacity to clear LDL from the bloodstream. This mechanism reveals that calcium plays an important role, particularly in how embelin mediates cholesterol levels through its effects on proteins involved in cholesterol metabolism.
Overall, the findings suggest that embelin may offer a natural avenue for improving cholesterol management, particularly in the context of cardiovascular health.
The study highlighted how embelin can elevate calcium levels within the endoplasmic reticulum (ER), which is essential for proper cellular function. By increasing calcium, we observed a decrease in the activity of a protein known as PCSK9, which typically hinders the liver's ability to remove low-density lipoprotein (LDL) cholesterol from circulation.
By regulating the levels of SREBP2, another protein linked to cholesterol control, embelin ultimately enhances the liver's capacity to clear LDL from the bloodstream. This mechanism reveals that calcium plays an important role, particularly in how embelin mediates cholesterol levels through its effects on proteins involved in cholesterol metabolism.
Overall, the findings suggest that embelin may offer a natural avenue for improving cholesterol management, particularly in the context of cardiovascular health.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 13 Reviews
7.4
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Aids fat metabolism
7 people found this helpful
Aiding in fat metabolism and cholesterol management, I find this product effective. I take it with inositol after dinner and have noticed an increase in energy levels along with satisfactory results.
Read More
10
Maintains clear skin
3 people found this helpful
It helps control my breakouts and oily skin. I cleared my hormonal cystic acne in just a few months with a maintenance dose, and I’ve kept it clear for three years now. Highly recommended!
Read More
9
Effective for acne
1 people found this helpful
I purchased this for my son, as high doses of pantothenic acid are effective against acne, and it has really worked for him.
Read More
9
Recommended for acne
1 people found this helpful
My acne has cleared right up with these. During my hormonal cycle, I take six a day; otherwise, I take three. They keep my skin clear, and I've experienced no side effects over the past four months.
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2
No cholesterol improvement
I haven't noticed any significant difference since I began taking this product. I can't identify any specific effect, nor have I observed any improvement in my cholesterol levels.
Read More
Frequently Asked Questions
6
Minimal cholesterol impact
1 people found this helpful
Pantothenic acid, known as vitamin B5, assists in synthesising immune antibodies, detoxifying drugs, increasing good cholesterol to enhance lipid metabolism, and is also involved in hormone production. While it seems beneficial for irritability, the dosage of 5 mg per day for an adult woman is considerable. However, as it is a water-soluble vitamin, taking it in excess appears to pose no health risks. I have dyslipidaemia and tried it, but I did not observe any significant changes. My HDL cholesterol did increase slightly, so I query whether it had any effect.
2
No cholesterol improvement
I haven't noticed any significant difference since I began taking this product. I can't identify any specific effect, nor have I observed any improvement in my cholesterol levels.
10
Maintains clear skin
3 people found this helpful
It helps control my breakouts and oily skin. I cleared my hormonal cystic acne in just a few months with a maintenance dose, and I’ve kept it clear for three years now. Highly recommended!
9
Recommended for acne
1 people found this helpful
My acne has cleared right up with these. During my hormonal cycle, I take six a day; otherwise, I take three. They keep my skin clear, and I've experienced no side effects over the past four months.
6
Reduced sebum production
54 people found this helpful
I highly recommend this product for oily skin concerned with sebum production. Initially, I took one tablet at night and one in the morning, feeling little effect. I increased now to two tablets each time. Now, my T-zone remains smooth even hours after applying makeup, and my sebum secretion has significantly decreased. As a result, my acne occurrences have lessened. Although I haven't noticed stress relief yet, this product is effective at this price, and I’m worried it might suddenly stop working.
7.5
Effective acne prevention
8 people found this helpful
I find pantothenic acid effective for preventing acne. I take one tablet in the morning and another in the evening when I notice excess oil in my T-zone. It helps to prolong my makeup wear and is especially beneficial around menstruation when skin issues are more prevalent.
7.5
Aids fat metabolism
7 people found this helpful
Aiding in fat metabolism and cholesterol management, I find this product effective. I take it with inositol after dinner and have noticed an increase in energy levels along with satisfactory results.
9
We examined the effects of embelin, a compound derived from the dried berries of Embelia ribes, on cholesterol levels by focusing on its relationship with calcium in liver cells. Our analysis showed that embelin treatment aids in regulating cholesterol metabolism by influencing key proteins associated with cholesterol clearance.
The study highlighted how embelin can elevate calcium levels within the endoplasmic reticulum (ER), which is essential for proper cellular function. By increasing calcium, we observed a decrease in the activity of a protein known as PCSK9, which typically hinders the liver's ability to remove low-density lipoprotein (LDL) cholesterol from circulation.
By regulating the levels of SREBP2, another protein linked to cholesterol control, embelin ultimately enhances the liver's capacity to clear LDL from the bloodstream. This mechanism reveals that calcium plays an important role, particularly in how embelin mediates cholesterol levels through its effects on proteins involved in cholesterol metabolism.
Overall, the findings suggest that embelin may offer a natural avenue for improving cholesterol management, particularly in the context of cardiovascular health.
The study highlighted how embelin can elevate calcium levels within the endoplasmic reticulum (ER), which is essential for proper cellular function. By increasing calcium, we observed a decrease in the activity of a protein known as PCSK9, which typically hinders the liver's ability to remove low-density lipoprotein (LDL) cholesterol from circulation.
By regulating the levels of SREBP2, another protein linked to cholesterol control, embelin ultimately enhances the liver's capacity to clear LDL from the bloodstream. This mechanism reveals that calcium plays an important role, particularly in how embelin mediates cholesterol levels through its effects on proteins involved in cholesterol metabolism.
Overall, the findings suggest that embelin may offer a natural avenue for improving cholesterol management, particularly in the context of cardiovascular health.
References
- Chandran M, Rameshkumar KB, Jaleel A, Ayyappan JP. Embelin Elevates Endoplasmic Reticulum Calcium Levels and Blocks the Sterol Regulatory Element-Binding Protein 2 Mediated Proprotein Convertase Subtilisin/Kexin Type 9 Expression and Improves the Low-Density Lipoprotein Receptor Mediated Lipid Clearance on Hepatocytes. Chem Biol Drug Des. 2025;105:e70055. 10.1111/cbdd.70055
