Speaking as someone with many GI issues, Align was recommended to me many months ago by my "Gastro" Dr. as part of my new "let's get better" regimen. It takes a couple of weeks to really get your digestive system going but, HOLY COW!!, this stuff is great. My nausea was gone and my "plumbing" was now in good working order. I did make some dietary changes like staying away from foods that clearly bothered me and were hard to digest and also added Zegerid OTC. I feel fantastic!!! You all do need to know that this is not like taking an aspirin for a Headache. It must be taken daily forever or for as long as you see fit. I'm NOT a Doctor. I'm just a very satisfied customer. In good health to you all