Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
USERS' SCORE
Good
Based on 3 Reviews
8.3
Top Medical Research Studies
9.5
We explored the potential of a new composite hydrogel that combines probiotics and fucoidan to aid oral ulcer healing. This study focused on how this hydrogel adheres to tissue and releases probiotics effectively. Remarkably, the hydrogels showed better therapeutic results compared to standard oral ulcer patches by promoting faster cell migration and healing.
Overall, this innovative approach suggests a promising future for treating oral ulcers more effectively than traditional methods.
Overall, this innovative approach suggests a promising future for treating oral ulcers more effectively than traditional methods.
Read More
9
We explored the effects of delivering human epidermal growth factor (EGF) through a probiotic strain of E. coli to help treat intestinal ulcers. The study showed that treatment with EGF-EcN not only alleviated ulcers but also helped in restoring damaged barrier layers in the gut. We observed that this method promotes the recovery of important cell types and strengthens mucosal integrity. Importantly, the probiotic did not worsen any cancerous conditions related to ulcerative colitis. Overall, our findings suggest that using probiotics to deliver helpful proteins like EGF can be a safe and effective strategy for managing gastrointestinal ulcers.
Read More
9
We recently explored the protective effects of a specific probiotic called Bifidobacterium breve (Bif195) on small-intestinal damage caused by acetylsalicylic acid (ASA), a common pain reliever. In a randomized, double-blind trial involving 75 healthy volunteers, participants took daily doses of either Bif195 or a placebo for eight weeks.
The results were promising! Those who took Bif195 experienced significantly lower levels of intestinal damage and fewer ulcers compared to the placebo group. Importantly, the use of Bif195 was well tolerated with minimal adverse events reported.
The results were promising! Those who took Bif195 experienced significantly lower levels of intestinal damage and fewer ulcers compared to the placebo group. Importantly, the use of Bif195 was well tolerated with minimal adverse events reported.
Read More
Most Useful Reviews
7.5
Relieves ulcer pain
1 people found this helpful
These greatly assist with my husband's ulcerative colitis symptoms. He suffers severe pain and other issues, but after starting probiotics, we noticed an immediate improvement. In just three weeks, he feels much better and more regular, experiencing far less pain unless he eats something unsuitable. Highly recommend these!
Read More
7.5
Effective for ulcer
2 people found this helpful
Don't let the price deter you! These are fantastic! I tried another reputable brand, but they didn't help as much as this one. I have early signs of a stomach ulcer, and these have significantly alleviated my gas. I am unsure why my doctor didn’t recommend these, but I'm pleased I discovered them.
Read More
7.5
Helps with ulcer treatment
1 people found this helpful
Recommended by a physician, I sought help for a rectal ulcer. A doctor advised taking mineral oil twice a day alongside Align, which significantly improved my digestive health. Although I tried cheaper probiotics, none were as effective as Align. I wholeheartedly support this product, especially considering I can purchase 63 capsules at once on Amazon!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
- All Researches
9.5
We constructed acute gastric ulcer models in mice by administering hydrochloric acid and ethanol, then introduced white jade snail secretion (WJSS) through gastric infusion. Our findings revealed that WJSS significantly reduced ulcer areas and levels of harmful substances like malondialdehyde.
The highest concentration of WJSS led to the most remarkable reduction in ulcers and improved intestinal bacteria diversity. This suggests that WJSS not only offers promising anti-ulcer effects but also promotes beneficial gut probiotics, pointing towards its potential use in ulcer treatment.
The highest concentration of WJSS led to the most remarkable reduction in ulcers and improved intestinal bacteria diversity. This suggests that WJSS not only offers promising anti-ulcer effects but also promotes beneficial gut probiotics, pointing towards its potential use in ulcer treatment.
Read More
9.5
We explored the potential of a new composite hydrogel that combines probiotics and fucoidan to aid oral ulcer healing. This study focused on how this hydrogel adheres to tissue and releases probiotics effectively. Remarkably, the hydrogels showed better therapeutic results compared to standard oral ulcer patches by promoting faster cell migration and healing.
Overall, this innovative approach suggests a promising future for treating oral ulcers more effectively than traditional methods.
Overall, this innovative approach suggests a promising future for treating oral ulcers more effectively than traditional methods.
Read More
9
We explored the effects of delivering human epidermal growth factor (EGF) through a probiotic strain of E. coli to help treat intestinal ulcers. The study showed that treatment with EGF-EcN not only alleviated ulcers but also helped in restoring damaged barrier layers in the gut. We observed that this method promotes the recovery of important cell types and strengthens mucosal integrity. Importantly, the probiotic did not worsen any cancerous conditions related to ulcerative colitis. Overall, our findings suggest that using probiotics to deliver helpful proteins like EGF can be a safe and effective strategy for managing gastrointestinal ulcers.
Read More
9
We recently explored the protective effects of a specific probiotic called Bifidobacterium breve (Bif195) on small-intestinal damage caused by acetylsalicylic acid (ASA), a common pain reliever. In a randomized, double-blind trial involving 75 healthy volunteers, participants took daily doses of either Bif195 or a placebo for eight weeks.
The results were promising! Those who took Bif195 experienced significantly lower levels of intestinal damage and fewer ulcers compared to the placebo group. Importantly, the use of Bif195 was well tolerated with minimal adverse events reported.
The results were promising! Those who took Bif195 experienced significantly lower levels of intestinal damage and fewer ulcers compared to the placebo group. Importantly, the use of Bif195 was well tolerated with minimal adverse events reported.
Read More
8
Topical probiotics boost ulcer healing
We investigated how probiotics influence healing in traumatic ulcers using an animal model. In our study, we organized rats into control, topical, and systemic probiotic groups to observe differences in healing.
After treatment, we noted that the topical administration of probiotics significantly improved the expression of important healing factors, like TNF-α, and increased the presence of immune cells that aid in recovery.
Our findings suggest that topical probiotics may be more effective than systemic methods for treating traumatic ulcers.
After treatment, we noted that the topical administration of probiotics significantly improved the expression of important healing factors, like TNF-α, and increased the presence of immune cells that aid in recovery.
Our findings suggest that topical probiotics may be more effective than systemic methods for treating traumatic ulcers.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Relieves ulcer pain
1 people found this helpful
These greatly assist with my husband's ulcerative colitis symptoms. He suffers severe pain and other issues, but after starting probiotics, we noticed an immediate improvement. In just three weeks, he feels much better and more regular, experiencing far less pain unless he eats something unsuitable. Highly recommend these!
Read More
7.5
Effective for ulcer
2 people found this helpful
Don't let the price deter you! These are fantastic! I tried another reputable brand, but they didn't help as much as this one. I have early signs of a stomach ulcer, and these have significantly alleviated my gas. I am unsure why my doctor didn’t recommend these, but I'm pleased I discovered them.
Read More
7.5
Helps with ulcer treatment
1 people found this helpful
Recommended by a physician, I sought help for a rectal ulcer. A doctor advised taking mineral oil twice a day alongside Align, which significantly improved my digestive health. Although I tried cheaper probiotics, none were as effective as Align. I wholeheartedly support this product, especially considering I can purchase 63 capsules at once on Amazon!
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Savitri IJ, Suprarahardiani SA, Ulinnuha LK, Prahasanti C, Wijaksana IKE, et al. TNF-α Expression and Plasma Cell and Macrophage Numbers in Traumatic Ulcers in a Rat Model Treated by Topical or Systemic Probiotic . Int J Med Sci. 2025;22:318. doi:10.7150/ijms.99156
- Cheng Q, Wang K, Lu R, Xiong Y, Luo X, et al. Effect of white jade snail secretion on antioxidant capacity and intestinal microbial diversity in mouse model of acute gastric ulcer. J Sci Food Agric. 2024;104:1723. doi:10.1002/jsfa.13059
- Dou X, Li G, Wang S, Shao D, Wang D, et al. Probiotic-loaded calcium alginate/fucoidan hydrogels for promoting oral ulcer healing. Int J Biol Macromol. 2023;244:125273. doi:10.1016/j.ijbiomac.2023.125273
- Isik M, Ozbayer C, Donmez DB, Colak E, Ustuner MC, et al. Effects of the probiotic, , on ulcer pathogenesis, HSP70 stress protein and nitric oxide levels in stress induced ulcer. Biotech Histochem. 2022;97:449. doi:10.1080/10520295.2022.2028308
- Vijayasarathy S, Gayathri P, Suneetha V. Fermented Foods and Their Abating Role in Gastric Ulcers. J Am Nutr Assoc. 2022;41:826. doi:10.1080/07315724.2021.1962768
- Yu M, Kim J, Ahn JH, Moon Y. Nononcogenic restoration of the intestinal barrier by E. coli-delivered human EGF. JCI Insight. 2019;4. doi:10.1172/jci.insight.125166
- Mortensen B, Murphy C, O'Grady J, Lucey M, Elsafi G, et al. Bifidobacteriumbreve Bif195 Protects Against Small-Intestinal Damage Caused by Acetylsalicylic Acid in Healthy Volunteers. Gastroenterology. 2019;157:637. doi:10.1053/j.gastro.2019.05.008
