Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Moderately Good
Based on 19 Reviews
7.9
Supplement Facts
Serving Size: 1 Capsule
Serving Per Container: 120
Amount Per Serving
%DV
Alpha Lipoic Acid
600 mg
*
Top Medical Research Studies
8
We explored the protective effects of alpha-lipoic acid (LA) against liver damage caused by arsenic, a well-known environmental toxin. In our examination, we uncovered the mechanisms through which arsenic harms the liver, including its ability to induce autophagy, apoptosis, and oxidative stress, as well as disrupt lipid metabolism.
Our findings revealed that arsenic negatively impacts liver function primarily by reducing the expression of SIRT1, damaging mitochondria, and impairing a process called peroxisomal β-oxidation. This disruption leads to an increase in lipid accumulation and enhances lipophagy, which is the body's way of breaking down fats. However, when we administered LA, we observed a marked improvement. LA appeared to counteract the damage inflicted by arsenic by boosting SIRT1 levels, improving mitochondrial function, and encouraging peroxisomal β-oxidation.
This study clearly illustrates the potential of alpha-lipoic acid as a protective agent against liver injury due to arsenic exposure. By promoting better lipid metabolism and reducing harmful fat buildup, LA could serve as a valuable option for those affected by liver diseases induced by environmental toxins.
Our findings revealed that arsenic negatively impacts liver function primarily by reducing the expression of SIRT1, damaging mitochondria, and impairing a process called peroxisomal β-oxidation. This disruption leads to an increase in lipid accumulation and enhances lipophagy, which is the body's way of breaking down fats. However, when we administered LA, we observed a marked improvement. LA appeared to counteract the damage inflicted by arsenic by boosting SIRT1 levels, improving mitochondrial function, and encouraging peroxisomal β-oxidation.
This study clearly illustrates the potential of alpha-lipoic acid as a protective agent against liver injury due to arsenic exposure. By promoting better lipid metabolism and reducing harmful fat buildup, LA could serve as a valuable option for those affected by liver diseases induced by environmental toxins.
Read More
8
Alpha-lipoic acid improves liver health
We conducted a clinical trial to evaluate the effectiveness of a special formulation combining alpha-lipoic acid (ALA) with a Mediterranean diet in improving liver health for individuals with metabolic dysfunction-associated steatosis (MASLD). In this study, patients were divided into two groups: one received the ALA and Mediterranean diet while the other was given a placebo along with the Mediterranean diet over a span of 24 weeks.
Throughout the trial, we carefully measured various health indicators and liver function. Our findings were promising; those who took the ALA alongside the Mediterranean diet showed significant reductions in visceral fat and waist circumference, translating to improvements in metabolic parameters. Notably, the controlled attenuation parameter, an indicator of liver fat, steadily decreased in this group, reinforcing the potential benefits of ALA in conjunction with a healthy diet.
While both groups reported mild side effects at similar rates, these did not overshadow the positive outcomes associated with ALA and the Mediterranean diet. Overall, our results emphasize the potential of this combination approach in enhancing liver health among individuals dealing with MASLD.
Throughout the trial, we carefully measured various health indicators and liver function. Our findings were promising; those who took the ALA alongside the Mediterranean diet showed significant reductions in visceral fat and waist circumference, translating to improvements in metabolic parameters. Notably, the controlled attenuation parameter, an indicator of liver fat, steadily decreased in this group, reinforcing the potential benefits of ALA in conjunction with a healthy diet.
While both groups reported mild side effects at similar rates, these did not overshadow the positive outcomes associated with ALA and the Mediterranean diet. Overall, our results emphasize the potential of this combination approach in enhancing liver health among individuals dealing with MASLD.
Read More
Most Useful Reviews
9
Improves liver health
2 people found this helpful
Great price! I would choose alpha-lipoic acid for health. Its effects benefit the nerves, liver, and blood sugar levels. This quality product is offered at a great price—highly recommended!
Read More
9
Strengthens liver function
1 people found this helpful
An excellent product at an affordable price. The small capsules and neutral taste make it easy to take. Alpha-lipoic acid combats oxidation effectively, improves blood vessel health, and has helped me feel more energised without fatigue. It’s essential for diabetics and aids liver detoxification.
Read More
9
Detoxifies liver effectively
1 people found this helpful
Alpha-lipoic acid is a unique antioxidant that helps in energy production and detoxifying the liver. The quality is exceptional with small capsules. I noticed a clearer head and improved skin quality—essential for diabetics and liver detoxification.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
- All Researches
8
We explored the protective effects of alpha-lipoic acid (LA) against liver damage caused by arsenic, a well-known environmental toxin. In our examination, we uncovered the mechanisms through which arsenic harms the liver, including its ability to induce autophagy, apoptosis, and oxidative stress, as well as disrupt lipid metabolism.
Our findings revealed that arsenic negatively impacts liver function primarily by reducing the expression of SIRT1, damaging mitochondria, and impairing a process called peroxisomal β-oxidation. This disruption leads to an increase in lipid accumulation and enhances lipophagy, which is the body's way of breaking down fats. However, when we administered LA, we observed a marked improvement. LA appeared to counteract the damage inflicted by arsenic by boosting SIRT1 levels, improving mitochondrial function, and encouraging peroxisomal β-oxidation.
This study clearly illustrates the potential of alpha-lipoic acid as a protective agent against liver injury due to arsenic exposure. By promoting better lipid metabolism and reducing harmful fat buildup, LA could serve as a valuable option for those affected by liver diseases induced by environmental toxins.
Our findings revealed that arsenic negatively impacts liver function primarily by reducing the expression of SIRT1, damaging mitochondria, and impairing a process called peroxisomal β-oxidation. This disruption leads to an increase in lipid accumulation and enhances lipophagy, which is the body's way of breaking down fats. However, when we administered LA, we observed a marked improvement. LA appeared to counteract the damage inflicted by arsenic by boosting SIRT1 levels, improving mitochondrial function, and encouraging peroxisomal β-oxidation.
This study clearly illustrates the potential of alpha-lipoic acid as a protective agent against liver injury due to arsenic exposure. By promoting better lipid metabolism and reducing harmful fat buildup, LA could serve as a valuable option for those affected by liver diseases induced by environmental toxins.
Read More
8
Alpha-lipoic acid improves liver health
We conducted a clinical trial to evaluate the effectiveness of a special formulation combining alpha-lipoic acid (ALA) with a Mediterranean diet in improving liver health for individuals with metabolic dysfunction-associated steatosis (MASLD). In this study, patients were divided into two groups: one received the ALA and Mediterranean diet while the other was given a placebo along with the Mediterranean diet over a span of 24 weeks.
Throughout the trial, we carefully measured various health indicators and liver function. Our findings were promising; those who took the ALA alongside the Mediterranean diet showed significant reductions in visceral fat and waist circumference, translating to improvements in metabolic parameters. Notably, the controlled attenuation parameter, an indicator of liver fat, steadily decreased in this group, reinforcing the potential benefits of ALA in conjunction with a healthy diet.
While both groups reported mild side effects at similar rates, these did not overshadow the positive outcomes associated with ALA and the Mediterranean diet. Overall, our results emphasize the potential of this combination approach in enhancing liver health among individuals dealing with MASLD.
Throughout the trial, we carefully measured various health indicators and liver function. Our findings were promising; those who took the ALA alongside the Mediterranean diet showed significant reductions in visceral fat and waist circumference, translating to improvements in metabolic parameters. Notably, the controlled attenuation parameter, an indicator of liver fat, steadily decreased in this group, reinforcing the potential benefits of ALA in conjunction with a healthy diet.
While both groups reported mild side effects at similar rates, these did not overshadow the positive outcomes associated with ALA and the Mediterranean diet. Overall, our results emphasize the potential of this combination approach in enhancing liver health among individuals dealing with MASLD.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 19 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improves liver health
2 people found this helpful
Great price! I would choose alpha-lipoic acid for health. Its effects benefit the nerves, liver, and blood sugar levels. This quality product is offered at a great price—highly recommended!
Read More
9
Strengthens liver function
1 people found this helpful
An excellent product at an affordable price. The small capsules and neutral taste make it easy to take. Alpha-lipoic acid combats oxidation effectively, improves blood vessel health, and has helped me feel more energised without fatigue. It’s essential for diabetics and aids liver detoxification.
Read More
9
Detoxifies liver effectively
1 people found this helpful
Alpha-lipoic acid is a unique antioxidant that helps in energy production and detoxifying the liver. The quality is exceptional with small capsules. I noticed a clearer head and improved skin quality—essential for diabetics and liver detoxification.
Read More
9
Improves liver function
Alpha-lipoic acid contains quality ingredients that deliver quick results. It is beneficial for adults needing liver function improvement and its effects are noticeable within days.
Read More
9
Restores liver cells
Alpha-lipoic acid, an antioxidant produced in cells, aids in promoting glucose absorption and restoring liver cells, preventing fatty degeneration, and is essential for energy metabolism.
Read More
Frequently Asked Questions
9
Improves liver function
Alpha-lipoic acid contains quality ingredients that deliver quick results. It is beneficial for adults needing liver function improvement and its effects are noticeable within days.
7.5
Regulates liver function
1 people found this helpful
This medicine normalises metabolic processes and reduces blood sugar. It enhances glucose absorption in liver cells, combats insulin resistance, and helps in fighting excess weight when coupled with diet and exercise. Alpha-lipoic acid also improves nerve functionality and aids in managing symptoms from liver disease.
7.5
Eases liver load
3 people found this helpful
I purchased alpha-lipoic acid for liver health as it lessens its workload and aids in the removal of toxins. It also helps regulate blood sugar and enhances tissue sensitivity to insulin. The quality is high, and the packaging is generous.
7.5
Weight loss aid
I took this supplement to improve liver function, and it worked excellently, reducing weight and appetite. I continue to take it due to its beneficial effects on liver disease.
9
Strengthens liver function
1 people found this helpful
An excellent product at an affordable price. The small capsules and neutral taste make it easy to take. Alpha-lipoic acid combats oxidation effectively, improves blood vessel health, and has helped me feel more energised without fatigue. It’s essential for diabetics and aids liver detoxification.
7.5
Cell sensitivity improvement
This product is of good quality, acting as an antioxidant that enhances cell sensitivity to insulin, which aids in reducing blood sugar and improving liver function, thus combating liver disease.
7.5
Boosts liver function
18 people found this helpful
Universal antioxidant alpha-lipoic acid is lipid and water-soluble, acting as an antioxidant in various body tissues. Its remarkable properties promote cardiovascular and cognitive health, aid in detoxification, and provide benefits for conditions characterised by oxidative stress, including liver disease. To enhance absorption, it should be taken on an empty stomach. Zinc, iron, and copper should be consumed four hours post-usage. The product quality is excellent, and the capsules are of average size with convenient packaging.
7.5
Insulin resistance assistance
7 people found this helpful
Alpha-lipoic acid is crucial for a healthy lifestyle, reducing blood glucose, aiding in liver glycogen levels, and improving liver function, while cautioning about possible weakness if iron levels are low.
7.5
Good antioxidant properties
This bottle of alpha-lipoic acid has 600 mg, sufficient for daily intake. It is an energy-supplementing product with good antioxidant properties that combats free radicals, thus aiding in the prevention of liver disease.
8
We explored the protective effects of alpha-lipoic acid (LA) against liver damage caused by arsenic, a well-known environmental toxin. In our examination, we uncovered the mechanisms through which arsenic harms the liver, including its ability to induce autophagy, apoptosis, and oxidative stress, as well as disrupt lipid metabolism.
Our findings revealed that arsenic negatively impacts liver function primarily by reducing the expression of SIRT1, damaging mitochondria, and impairing a process called peroxisomal β-oxidation. This disruption leads to an increase in lipid accumulation and enhances lipophagy, which is the body's way of breaking down fats. However, when we administered LA, we observed a marked improvement. LA appeared to counteract the damage inflicted by arsenic by boosting SIRT1 levels, improving mitochondrial function, and encouraging peroxisomal β-oxidation.
This study clearly illustrates the potential of alpha-lipoic acid as a protective agent against liver injury due to arsenic exposure. By promoting better lipid metabolism and reducing harmful fat buildup, LA could serve as a valuable option for those affected by liver diseases induced by environmental toxins.
Our findings revealed that arsenic negatively impacts liver function primarily by reducing the expression of SIRT1, damaging mitochondria, and impairing a process called peroxisomal β-oxidation. This disruption leads to an increase in lipid accumulation and enhances lipophagy, which is the body's way of breaking down fats. However, when we administered LA, we observed a marked improvement. LA appeared to counteract the damage inflicted by arsenic by boosting SIRT1 levels, improving mitochondrial function, and encouraging peroxisomal β-oxidation.
This study clearly illustrates the potential of alpha-lipoic acid as a protective agent against liver injury due to arsenic exposure. By promoting better lipid metabolism and reducing harmful fat buildup, LA could serve as a valuable option for those affected by liver diseases induced by environmental toxins.
8
Alpha-lipoic acid improves liver health
We conducted a clinical trial to evaluate the effectiveness of a special formulation combining alpha-lipoic acid (ALA) with a Mediterranean diet in improving liver health for individuals with metabolic dysfunction-associated steatosis (MASLD). In this study, patients were divided into two groups: one received the ALA and Mediterranean diet while the other was given a placebo along with the Mediterranean diet over a span of 24 weeks.
Throughout the trial, we carefully measured various health indicators and liver function. Our findings were promising; those who took the ALA alongside the Mediterranean diet showed significant reductions in visceral fat and waist circumference, translating to improvements in metabolic parameters. Notably, the controlled attenuation parameter, an indicator of liver fat, steadily decreased in this group, reinforcing the potential benefits of ALA in conjunction with a healthy diet.
While both groups reported mild side effects at similar rates, these did not overshadow the positive outcomes associated with ALA and the Mediterranean diet. Overall, our results emphasize the potential of this combination approach in enhancing liver health among individuals dealing with MASLD.
Throughout the trial, we carefully measured various health indicators and liver function. Our findings were promising; those who took the ALA alongside the Mediterranean diet showed significant reductions in visceral fat and waist circumference, translating to improvements in metabolic parameters. Notably, the controlled attenuation parameter, an indicator of liver fat, steadily decreased in this group, reinforcing the potential benefits of ALA in conjunction with a healthy diet.
While both groups reported mild side effects at similar rates, these did not overshadow the positive outcomes associated with ALA and the Mediterranean diet. Overall, our results emphasize the potential of this combination approach in enhancing liver health among individuals dealing with MASLD.
References
- Zhao Y, Guo M, Pei T, Shang C, Chen Y, et al. α-Lipoic Acid Ameliorates Arsenic-Induced Lipid Disorders by Promoting Peroxisomal β-Oxidation and Reducing Lipophagy in Chicken Hepatocyte. Adv Sci (Weinh). 2025. doi:10.1002/advs.202413255
- Cano Contreras AD, Del Rocío Francisco M, Vargas Basurto JL, Gonzalez-Gomez KD, Amieva-Balmori M, et al. Effect of alpha-lipoic acid and supplementation with a Mediterranean diet on metabolic dysfunction-associated steatosis. World J Hepatol. 2025;17:101704. doi:10.4254/wjh.v17.i1.101704
