We focused on understanding the impact of vitamin D supplementation on atopic dermatitis, commonly known as eczema, in both children and adults. This systematic review analyzed data from eleven randomized controlled trials (RCTs), involving a total of 686 participants.
Each study compared participants receiving vitamin D to those in control groups, measuring their eczema severity using established scoring systems. The results were compelling. We found that vitamin D supplementation led to a noteworthy reduction in eczema severity compared to those who did not receive this treatment.
Specifically, the analysis indicated a standardized mean difference of -0.41, suggesting significant benefits for individuals taking vitamin D. However, it’s essential to note that while the findings are promising, larger and longer-term studies are necessary to confirm these results.
Read More
8
Neonatal vitamin D influences eczema
Neonatal Vitamin D and Associations with Longitudinal Changes of Eczema up to 25 Years of Age.
We observed the potential effects of early-life vitamin D levels on the risk of developing eczema in children over a 25-year period. Our study involved measuring the levels of 25(OH)D3 from dried blood spots in 223 children at high risk for allergies. We then used statistical methods to assess different types of eczema that might occur as the children grew.
The findings revealed that higher levels of neonatal vitamin D were linked to a reduced risk of persistent eczema that starts early in life. Specifically, for every 10 nmol/L increase in vitamin D, there was about a 26% lower chance of developing early-onset persistent eczema. Conversely, these higher levels also seemed to increase the odds of early-onset-resolving eczema by around 30%.
However, it’s important to note that we did not find strong evidence connecting neonatal vitamin D levels with current eczema or other distinct eczema-related sensitization patterns. Overall, our results suggest that ensuring adequate vitamin D levels during pregnancy could potentially benefit the long-term skin health of children, particularly regarding the emergence of certain eczema types.
Read More
8
Vitamin D improves eczema symptoms
Oral vitamin D modulates the epidermal expression of the vitamin D receptor and cathelicidin in children with atopic dermatitis.
We investigated how oral vitamin D3 supplements influence eczema, specifically in children with atopic dermatitis (AD). Over six weeks, we administered weekly doses of vitamin D3 to a group of 22 children suffering from moderate to severe AD.
Before and after the treatment, we measured several key factors: serum vitamin D levels, the presence of Staphylococcus aureus on the skin, and the overall severity of eczema, assessed through the SCORAD index.
Remarkably, we found that vitamin D supplementation raised vitamin D levels in the children and led to significant improvements in eczema severity. The SCORAD scores dropped notably, indicating less severe symptoms. Additionally, we saw an increase in the expression of vital skin proteins, specifically Cathelicidin, in affected areas after treatment.
However, while the treatment was beneficial for overall skin condition, the expression of Thymic Stromal Lymphopoietin did not change. Importantly, our findings highlight the direct effects of vitamin D on skin health in children with AD, providing insight into its potential as a supportive treatment for eczema.
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Most Useful Reviews
9
Great for eczema
Superb! This has been a fantastic probiotic for my daughter, who suffers from eczema. It helps relieve her itch at night!
Read More
9
Effective against issues
It worked! When my son had gas problems alongside eczema, we tried this, and both issues disappeared by the time we finished the bottle. I mixed it with baby food, and he took it without any problems. Just ensure to shake it well before use.
Read More
7.5
Less gassy baby
1 people found this helpful
My baby has become less gassy since starting this weeks ago. It's easy to drop in her mouth, with no need to force-feed or chew tablets. It’s simple and fuss-free! Moreover, it contains good strains of bacteria that help keep her eczema at bay.
We investigated the levels of vitamin D and other related factors in children suffering from eczema to better understand their relationship with the severity of this condition. Our analysis included 159 children, categorized by the severity of their eczema symptoms into mild, moderate, and severe groups.
Over the course of the study, we observed that as eczema severity increased, serum levels of vitamin A and 25-(OH)D3 (a form of vitamin D) tended to decrease. Conversely, levels of tissue transglutaminase (TG2), interleukin-4 (IL-4), and interleukin-13 (IL-13), which are markers of inflammation, increased. Significant correlations emerged showing that lower levels of vitamin A and 25-(OH)D3 were linked to higher SCORAD scores (a measure of eczema severity), while increases in TG2, IL-4, and IL-13 levels paralleled worsening symptoms.
Importantly, vitamin D levels had the highest accuracy for assessing eczema severity compared to the other markers studied. After treatment over three months, we noted improvements in the levels of all measured indicators, suggesting that addressing these serum factors could have a positive impact on managing eczema symptoms.
Our findings indicate that monitoring vitamin D levels, along with other serum indicators, might offer valuable insights for clinicians in evaluating and treating eczema in children.
Read More
8
Vitamin D reduces eczema severity
Vitamin D Supplementation for Treating Atopic Dermatitis in Children and Adults: A Systematic Review and Meta-Analysis.
We focused on understanding the impact of vitamin D supplementation on atopic dermatitis, commonly known as eczema, in both children and adults. This systematic review analyzed data from eleven randomized controlled trials (RCTs), involving a total of 686 participants.
Each study compared participants receiving vitamin D to those in control groups, measuring their eczema severity using established scoring systems. The results were compelling. We found that vitamin D supplementation led to a noteworthy reduction in eczema severity compared to those who did not receive this treatment.
Specifically, the analysis indicated a standardized mean difference of -0.41, suggesting significant benefits for individuals taking vitamin D. However, it’s essential to note that while the findings are promising, larger and longer-term studies are necessary to confirm these results.
Read More
8
Maternal vitamin D influences infant eczema
Correlation of Maternal Vitamin D Status in Early Pregnancy and Vitamin D Supplementation during Pregnancy with Atopic Dermatitis in Infants: A Prospective Birth Cohort Study.
We examined the relationship between maternal vitamin D levels during early pregnancy and the occurrence of atopic dermatitis (AD), commonly known as eczema, in infants. Our study involved 4,051 woman-infant pairs, focusing on those with singleton pregnancies. We looked closely at the vitamin D levels of mothers in their first trimester and analyzed how these levels, along with vitamin D supplementation during pregnancy, influenced the likelihood of infants developing AD.
The results showed that infants born to mothers with low vitamin D levels faced a significantly higher risk of developing eczema. Specifically, mothers with vitamin D deficiency had a 77% increased risk of their infants developing AD. Interestingly, this heightened risk was mostly observed in naturally conceived pregnancies, while those conceived through assisted reproductive techniques didn't show the same association.
Additionally, we found that mothers who took vitamin D or multivitamin supplements during pregnancy had a lower risk of having infants with AD. This suggests that adequate vitamin D intake may play a protective role against eczema in infants. Our findings underscore the importance of monitoring vitamin D levels in expectant mothers, as doing so could help reduce the risk of eczema in their future children.
Read More
8
Vitamin D's unclear role in eczema
A systematic review and meta-analysis of nutritional and dietary interventions in randomized controlled trials for skin symptoms in children with atopic dermatitis and without food allergy: An EAACI task force report.
We explored the effectiveness of dietary interventions, particularly vitamin D, in treating eczema symptoms in children without food allergies. Our systematic review included several randomized controlled trials (RCTs) that assessed various treatments. Among these, vitamin D was analyzed alongside other therapies like probiotics and evening primrose oil.
The findings revealed an overall trend suggesting that probiotics, especially when combined with prebiotics, could lead to a notable reduction in eczema symptoms as measured by standard scoring systems. However, the evidence specifically highlighting vitamin D's role in alleviating eczema was limited. This indicates that while some dietary approaches show promise, the impact of vitamin D alone remains less clear.
Thus, we recognize the need for more focused research that can specifically examine the effects of vitamin D on eczema, ideally isolating it from other dietary factors. Well-structured studies are essential to deepen our understanding and develop effective treatment strategies for managing eczema in children.
Read More
8
Neonatal vitamin D influences eczema
Neonatal Vitamin D and Associations with Longitudinal Changes of Eczema up to 25 Years of Age.
We observed the potential effects of early-life vitamin D levels on the risk of developing eczema in children over a 25-year period. Our study involved measuring the levels of 25(OH)D3 from dried blood spots in 223 children at high risk for allergies. We then used statistical methods to assess different types of eczema that might occur as the children grew.
The findings revealed that higher levels of neonatal vitamin D were linked to a reduced risk of persistent eczema that starts early in life. Specifically, for every 10 nmol/L increase in vitamin D, there was about a 26% lower chance of developing early-onset persistent eczema. Conversely, these higher levels also seemed to increase the odds of early-onset-resolving eczema by around 30%.
However, it’s important to note that we did not find strong evidence connecting neonatal vitamin D levels with current eczema or other distinct eczema-related sensitization patterns. Overall, our results suggest that ensuring adequate vitamin D levels during pregnancy could potentially benefit the long-term skin health of children, particularly regarding the emergence of certain eczema types.
Superb! This has been a fantastic probiotic for my daughter, who suffers from eczema. It helps relieve her itch at night!
Read More
9
Effective against issues
It worked! When my son had gas problems alongside eczema, we tried this, and both issues disappeared by the time we finished the bottle. I mixed it with baby food, and he took it without any problems. Just ensure to shake it well before use.
Read More
7.5
Less gassy baby
1 people found this helpful
My baby has become less gassy since starting this weeks ago. It's easy to drop in her mouth, with no need to force-feed or chew tablets. It’s simple and fuss-free! Moreover, it contains good strains of bacteria that help keep her eczema at bay.
Read More
7.5
Doctor recommended
Very good! I have made multiple repurchases due to my daughter's eczema, which the doctor recommended treating with this product. It's much more effective than local alternatives.
Read More
7.5
Recommended for eczema
Without any taste, it would be beneficial to consume it, and it has been effective in reducing eczema. I recommend it.
Eczema, also known as atopic dermatitis, is a chronic skin condition characterized by inflamed, itchy, and red patches on the skin. It is most commonly seen in children but can occur at any age. The condition can range from mild to severe and often leads to dry, scaly skin that can become cracked or even bleed. Eczema is believed to be related to a combination of genetic predisposition, skin barrier dysfunction, and environmental factors, including allergens, irritants, and stress.
Treatment for eczema often involves a multi-faceted approach, including the use of moisturizers to keep the skin hydrated, topical corticosteroids to reduce inflammation, and, in some cases, antihistamines to alleviate itching. Identifying and avoiding triggers such as certain soaps, fabrics, or foods can also play a crucial role in managing the condition. While there is currently no cure for eczema, ongoing advancements in research have led to the development of new therapies, including biologic medications that target specific components of the immune response, offering hope for those with moderate to severe cases.
Children's probiotics are dietary supplements specifically formulated to provide beneficial bacteria that support digestive health and the immune system in children. These probiotics contain various strains of live microorganisms, often including Lactobacillus and Bifidobacterium, which are known to help maintain a healthy balance of gut bacteria. The gut microbiome plays a crucial role in children's overall health, influencing their digestion, immune function, and even mood. Many parents turn to children's probiotics to help address issues like constipation, diarrhea, or colic, as well as to support their child’s immunity, especially during cold and flu season.
When selecting a children's probiotic, it’s essential to consider factors such as the specific strains included, the number of colony-forming units (CFUs), and whether it is tailored to your child's specific health needs. Probiotics can come in various forms, including powders, gummies, and liquids, making them easy to administer to little ones. However, it’s always advisable to consult a pediatrician before starting any new supplement regime for your child, as they can provide personalized recommendations based on the child's health history and current needs.
While the connection between probiotics and eczema is still being researched, some studies suggest that children’s probiotics may offer benefits in managing eczema symptoms. Probiotics are live bacteria that can help balance the gut microbiome, and some evidence indicates that they may enhance skin barrier function and reduce inflammation. For instance, certain strains of probiotics, such as Lactobacillus rhamnosus, have shown promise in small studies as a potential way to alleviate eczema symptoms, particularly in infants and young children.
However, it’s important to approach this option carefully and consult with a pediatrician before starting any new supplement regimen for eczema. Individual responses to probiotics can vary, and what works for one child may not work for another. Moreover, while probiotics can be part of a comprehensive approach to managing eczema, including topical treatments and dietary considerations, they shouldn't replace traditional medical advice or treatment plans. Additional research is necessary to determine definitive benefits, but probiotics could be considered as one possible complementary approach in a holistic strategy for managing eczema in children.
Based on user reviews, the time it takes to see results from this supplement for eczema can vary, but many users report positive effects within a few weeks of starting the regimen. One reviewer noted that their child's eczema improved alongside gas issues after finishing a bottle of the supplement, indicating visible results in about a month's time Read Review. Another user mentioned significant improvement after starting the supplement weeks ago Read Review.
Additionally, several users have expressed satisfaction with the product's effectiveness for eczema relief, suggesting a sense of gradual improvement as they continued its use. Comments regarding enduring benefits and repurchases underscore a consistent positive feedback loop that suggests users can expect to see some changes relatively quickly, typically within a few weeks Read Review. Overall, while individual experiences may differ, a timeframe of a few weeks seems to be common among users looking for eczema relief.
There is growing scientific support for the role of vitamin D supplementation in managing eczema, particularly in children. A systematic review that analyzed eleven randomized controlled trials (RCTs) involving 686 participants found significant benefits from vitamin D supplementation, with a standardized mean difference indicating a noteworthy reduction in eczema severity compared to control groups [2]. Furthermore, research involving children showed that vitamin D levels correlated with the severity of eczema symptoms—lower levels were linked to increased severity as measured by established scoring systems [1]. In a separate study examining the long-term impacts of early-life vitamin D, increased neonatal levels were associated with a lower risk of developing persistent eczema [6].
While evidence suggests that vitamin D could effectively aid in reducing eczema severity, the relationship can be complex, with some studies indicating a need for larger, long-term investigations to fully understand the extent of its impact [9]. Additionally, randomized controlled trials specifically focusing on the benefits of prenatal vitamin D supplementation have demonstrated a protective effect against the development of eczema in infants [13]. This indicates that maintaining optimal vitamin D levels during pregnancy could be a beneficial strategy in preventing the onset of eczema in children. Overall, while results are promising, more targeted research into vitamin D's role in eczema treatment is warranted to confirm these findings.
Based on user reviews, many individuals have reported significant improvements in eczema symptoms after using this probiotic supplement. One user praised the product for helping relieve their daughter's nighttime itching, indicating enhanced comfort during sleep Read Review. Another parent shared that both their son's gas issues and eczema resolved after completing a bottle, showcasing the product's dual-action benefits Read Review. Several reviews highlight a noticeable reduction in symptoms, such as one user who remarked their baby became less gassy as well as managing to keep eczema at bay through the use of this simple probiotic Read Review.
A recurring theme in the reviews is the product's ease of use and effectiveness compared to local alternatives, with one user confirming multiple repurchases based on their child's positive response Read Review. Additionally, users noted benefits such as tastelessness and mild effectiveness in reducing eczema symptoms, suggesting a generally favorable experience Read Review. Overall, while results may vary, trending feedback indicates a promising improvement in eczema symptoms for many users.
Based on user reviews, many individuals have found success in combining this probiotic supplement with other dietary elements to manage eczema symptoms. One user highlighted that mixing the supplement with baby food made it easier for their son, who was experiencing both gas problems and eczema, resulting in a resolution of both issues by the end of the bottle Read Review. This suggests that integrating the supplement into meals can enhance compliance and effectiveness, particularly for younger users or those who may resist taking supplements directly.
Moreover, the convenience of administering the probiotic in a fuss-free manner has been noted by several parents, emphasizing that the ease of use plays a significant role in ensuring consistent intake. One reviewer commented on the ease of giving it to their baby without the fuss of traditional tablets, indicating a preference for a non-taste option that fits seamlessly into their daily routine Read Review. Overall, users appear to appreciate the ability to combine this probiotic with food while observing beneficial effects on eczema symptoms.
According to user reviews, there appears to be a consensus that Children's Probiotics can be beneficial in managing eczema symptoms. Many users report a noticeable improvement in their children's eczema after using the product. For instance, one review notes that a daughter experiencing itching at night found relief with this probiotic Read Review. Others indicate that combining the probiotic with baby food made it easier to administer, and they saw improvements in their children's gas issues and eczema symptoms simultaneously Read Review.
Overall, users seem to appreciate the ease of use, as the probiotic can simply be dropped into the mouth of younger children without fuss. The general sentiment is that consistent use, as indicated by multiple repurchases for ongoing eczema management, enhances its effectiveness Read Review. While the exact dosing recommended was not specified in the reviews, the anecdotal evidence suggests that parents find success when incorporating it into their daily routine.
9
Effective against issues
It worked! When my son had gas problems alongside eczema, we tried this, and both issues disappeared by the time we finished the bottle. I mixed it with baby food, and he took it without any problems. Just ensure to shake it well before use.
7.5
Less gassy baby
1 people found this helpful
My baby has become less gassy since starting this weeks ago. It's easy to drop in her mouth, with no need to force-feed or chew tablets. It’s simple and fuss-free! Moreover, it contains good strains of bacteria that help keep her eczema at bay.
7.5
Doctor recommended
Very good! I have made multiple repurchases due to my daughter's eczema, which the doctor recommended treating with this product. It's much more effective than local alternatives.
9
Great for eczema
Superb! This has been a fantastic probiotic for my daughter, who suffers from eczema. It helps relieve her itch at night!
7.5
Recommended for eczema
Without any taste, it would be beneficial to consume it, and it has been effective in reducing eczema. I recommend it.
8
Vitamin D reduces eczema severity
Vitamin D Supplementation for Treating Atopic Dermatitis in Children and Adults: A Systematic Review and Meta-Analysis.
We focused on understanding the impact of vitamin D supplementation on atopic dermatitis, commonly known as eczema, in both children and adults. This systematic review analyzed data from eleven randomized controlled trials (RCTs), involving a total of 686 participants.
Each study compared participants receiving vitamin D to those in control groups, measuring their eczema severity using established scoring systems. The results were compelling. We found that vitamin D supplementation led to a noteworthy reduction in eczema severity compared to those who did not receive this treatment.
Specifically, the analysis indicated a standardized mean difference of -0.41, suggesting significant benefits for individuals taking vitamin D. However, it’s essential to note that while the findings are promising, larger and longer-term studies are necessary to confirm these results.
8
Vitamin D's role in eczema severity
Changes and clinical significance of serum vitamin A, 25-(OH)D3, TG2, IL-4 and IL-13 levels in children with eczema.
We investigated the levels of vitamin D and other related factors in children suffering from eczema to better understand their relationship with the severity of this condition. Our analysis included 159 children, categorized by the severity of their eczema symptoms into mild, moderate, and severe groups.
Over the course of the study, we observed that as eczema severity increased, serum levels of vitamin A and 25-(OH)D3 (a form of vitamin D) tended to decrease. Conversely, levels of tissue transglutaminase (TG2), interleukin-4 (IL-4), and interleukin-13 (IL-13), which are markers of inflammation, increased. Significant correlations emerged showing that lower levels of vitamin A and 25-(OH)D3 were linked to higher SCORAD scores (a measure of eczema severity), while increases in TG2, IL-4, and IL-13 levels paralleled worsening symptoms.
Importantly, vitamin D levels had the highest accuracy for assessing eczema severity compared to the other markers studied. After treatment over three months, we noted improvements in the levels of all measured indicators, suggesting that addressing these serum factors could have a positive impact on managing eczema symptoms.
Our findings indicate that monitoring vitamin D levels, along with other serum indicators, might offer valuable insights for clinicians in evaluating and treating eczema in children.
8
Neonatal vitamin D influences eczema
Neonatal Vitamin D and Associations with Longitudinal Changes of Eczema up to 25 Years of Age.
We observed the potential effects of early-life vitamin D levels on the risk of developing eczema in children over a 25-year period. Our study involved measuring the levels of 25(OH)D3 from dried blood spots in 223 children at high risk for allergies. We then used statistical methods to assess different types of eczema that might occur as the children grew.
The findings revealed that higher levels of neonatal vitamin D were linked to a reduced risk of persistent eczema that starts early in life. Specifically, for every 10 nmol/L increase in vitamin D, there was about a 26% lower chance of developing early-onset persistent eczema. Conversely, these higher levels also seemed to increase the odds of early-onset-resolving eczema by around 30%.
However, it’s important to note that we did not find strong evidence connecting neonatal vitamin D levels with current eczema or other distinct eczema-related sensitization patterns. Overall, our results suggest that ensuring adequate vitamin D levels during pregnancy could potentially benefit the long-term skin health of children, particularly regarding the emergence of certain eczema types.
4
Vitamin D and eczema link examined
Is antenatal or early-life vitamin D associated with eczema or food allergy in childhood? A systematic review.
We examined the relationship between vitamin D levels and the development of eczema in childhood through a systematic review and meta-analysis of several studies. This research highlighted the experiences of 43 articles, including six randomized controlled trials (RCTs) and several cohort studies, to gather comprehensive insights on this topic.
Interestingly, while some cohort studies indicated that higher vitamin D levels in cord blood were associated with a reduced risk of eczema, the RCTs revealed no significant effect of vitamin D supplementation during pregnancy or infancy on eczema rates. In fact, the pooled odds ratio from four of these trials pointed toward no notable impact, suggesting that vitamin D alone might not be a reliable preventive measure for eczema.
Moreover, three RCTs tested vitamin D's role in food allergies but found no positive associations there either. So, while we observed a potential link between higher vitamin D at birth and lower eczema prevalence, the evidence from clinical trials indicates that vitamin D supplementation isn't a guaranteed solution for preventing eczema in children.
Overall, it seems that the role of vitamin D in childhood eczema requires further investigation, particularly through additional trials focusing on supplementation for mothers and infants.
8
Prenatal vitamin D reduces eczema risk
Maternal antenatal vitamin D supplementation and offspring risk of atopic eczema in the first 4 years of life: evidence from a randomized controlled trial.
We explored the potential impact of maternal vitamin D supplementation during pregnancy on the risk of developing atopic eczema in children up to four years old. In this well-structured study, pregnant women were randomly assigned to receive either 1000 IU of cholecalciferol, a form of vitamin D, or a placebo from around 14 weeks of gestation until delivery.
By assessing the prevalence of atopic eczema in their children at 12, 24, and 48 months, we aimed to gather solid evidence in a field where existing research has mostly stemmed from observational studies. Our findings indicate a notable protective effect of prenatal vitamin D supplementation against the risk of eczema in infants, suggesting that this supplement may improve breast milk cholecalciferol levels, which could benefit the child's skin health.
Overall, our data provide the first randomized controlled trial evidence supporting the idea that maternal vitamin D intake during pregnancy can play a role in reducing the incidence of eczema in young children. This opens the door for potentially important perinatal interventions that could positively affect children's health.
References
Li Y, Wang Z, Li X, Ma K, Shi Z. Changes and clinical significance of serum vitamin A, 25-(OH)D3, TG2, IL-4 and IL-13 levels in children with eczema. Arch Dermatol Res. 2025;317:375. doi:10.1007/s00403-025-03887-8
Nielsen AY, Høj S, Thomsen SF, Meteran H. Vitamin D Supplementation for Treating Atopic Dermatitis in Children and Adults: A Systematic Review and Meta-Analysis. Nutrients. 2024;16. doi:10.3390/nu16234128
Zhang Q, Yang D, Shen Q, Li W, Li R, et al. Correlation of Maternal Vitamin D Status in Early Pregnancy and Vitamin D Supplementation during Pregnancy with Atopic Dermatitis in Infants: A Prospective Birth Cohort Study. Nutrients. 2024;16. doi:10.3390/nu16132168
McCarthy RL, Tawfik SS, Theocharopoulos I, Atkar R, McDonald B, et al. Vitamin D deficiency and atopic dermatitis severity in a Bangladeshi population living in East London: A cross-sectional study. Skin Health Dis. 2024;4:e358. doi:10.1002/ski2.358
Vassilopoulou E, Comotti A, Douladiris N, Konstantinou GΝ, Zuberbier T, et al. A systematic review and meta-analysis of nutritional and dietary interventions in randomized controlled trials for skin symptoms in children with atopic dermatitis and without food allergy: An EAACI task force report. Allergy. 2024;79:1708. doi:10.1111/all.16160
Zeng R, Lodge CJ, Koplin JJ, Lopez DJ, Erbas B, et al. Neonatal Vitamin D and Associations with Longitudinal Changes of Eczema up to 25 Years of Age. Nutrients. 2024;16. doi:10.3390/nu16091303
Ding YJ, Li XN, Xiao Z, Li CY, Jia LH. Low vitamin D during pregnancy is associated with infantile eczema by up-regulation of PI3K/AKT/mTOR signaling pathway and affecting FOXP3 expression: A bidirectional cohort study. J Nutr Biochem. 2024;124:109516. doi:10.1016/j.jnutbio.2023.109516
Ziyab AH, Al-Taiar A, Al-Sabah R, Shaban L, Almousa Z, et al. Sex and obesity status modify the association between vitamin D and eczema among adolescents. Pediatr Res. 2023;94:1235. doi:10.1038/s41390-023-02641-y
Zeng R, Li Y, Shen S, Qiu X, Chang CL, et al. Is antenatal or early-life vitamin D associated with eczema or food allergy in childhood? A systematic review. Clin Exp Allergy. 2023;53:511. doi:10.1111/cea.14281
Cabalín C, Pérez-Mateluna G, Iturriaga C, Camargo CA, Borzutzky A. Oral vitamin D modulates the epidermal expression of the vitamin D receptor and cathelicidin in children with atopic dermatitis. Arch Dermatol Res. 2023;315:761. doi:10.1007/s00403-022-02416-1
Li Q, Zhou Q, Zhang G, Tian X, Li Y, et al. Vitamin D Supplementation and Allergic Diseases during Childhood: A Systematic Review and Meta-Analysis. Nutrients. 2022;14. doi:10.3390/nu14193947
Sangüesa J, Sunyer J, Garcia-Esteban R, Abellan A, Esplugues A, et al. Prenatal and child vitamin D levels and allergy and asthma in childhood. Pediatr Res. 2023;93:1745. doi:10.1038/s41390-022-02256-9
El-Heis S, D'Angelo S, Curtis EM, Healy E, Moon RJ, et al. Maternal antenatal vitamin D supplementation and offspring risk of atopic eczema in the first 4 years of life: evidence from a randomized controlled trial. Br J Dermatol. 2022;187:659. doi:10.1111/bjd.21721