We explored the effects of vitamin D (VD) on gut health during infections caused by a common foodborne bacterium. By using intestinal cells and mouse models, we looked at how this vitamin interacts with the body’s defenses and could potentially restore the gut’s protective barrier during these infections.
Our findings reveal that infections can disrupt gut barrier function and activate the immune system. In patients suffering from campylobacteriosis, we noted that the vitamin D receptor's (VDR) activity was reduced, indicating a weakening of immune responses.
When we supplemented with VD in lab settings, we noticed impressive barrier-preserving effects. In fact, VD reversed the impairment caused by the infection, supporting better functioning of tight junctions within the gut lining. This ultimately led to decreased bacteria moving across the gut barrier.
Overall, our research suggests that vitamin D could be a promising treatment in addressing gut turmoil caused by foodborne infections. It appears that VD supplementation could restore gut barrier functionality, providing a new avenue for both human and animal health.
Read More
8
Vitamin D enhances immune response
The differential effects of 1,25-dihydroxyvitamin D3 on Salmonella-induced interleukin-8 and human beta-defensin-2 in intestinal epithelial cells.
We explored the effect of 1,25-dihydroxyvitamin D3, a potent form of vitamin D, on the body's response to food poisoning caused by Salmonella. The research focused on how this vitamin influences key immune proteins produced by intestinal epithelial cells, which are crucial for fighting infections.
Our findings revealed that vitamin D treatment led to decreased levels of interleukin-8, a protein that promotes inflammation, in response to Salmonella. However, it notably enhanced the production of human beta-defensin-2, an important antimicrobial peptide that helps protect against infections.
These effects seem to stem from vitamin D's influence on specific cellular pathways, indicating that it could fine-tune our immune system’s response. By bolstering anti-microbial defense while tempering excessive inflammation, vitamin D may enhance our body’s ability to fend off Salmonella infections, suggesting a potential therapeutic strategy against foodborne diseases.
Read More
Most Useful Reviews
9
Best supplement
3 people found this helpful
This remedy for colic is effective! It tastes like oil; I use 5 drops with food, and it's the best option from birth. I can confidently say this is the best supplement that has significantly helped us.
Read More
9
Effective laxative
2 people found this helpful
My son has been constipated since starting baby food. I tried magnesium oxide, but once it was stopped, the issue returned. Since introducing this, he has been able to pass stools easily, marking a significant improvement.
Read More
9
Quick recovery noted
1 people found this helpful
Quick fix for nausea, diarrhoea, tummy ache, or even flu symptoms! This strain of bacteria is especially beneficial for children experiencing these issues. With just a couple of doses, they show noticeable improvement. It is best taken on an empty stomach a few minutes before food. The taste is tolerable, even for babies. I can guarantee the quality as its action is quite fast. Within 2-3 days of usage (as often as needed), my child felt better. I once used it on my elderly mother who suffered from severe gastroenteritis, and after one dose, she stopped vomiting. You just need to keep taking it every few hours to balance the gut bacteria.
We explored the effects of vitamin D (VD) on gut health during infections caused by a common foodborne bacterium. By using intestinal cells and mouse models, we looked at how this vitamin interacts with the body’s defenses and could potentially restore the gut’s protective barrier during these infections.
Our findings reveal that infections can disrupt gut barrier function and activate the immune system. In patients suffering from campylobacteriosis, we noted that the vitamin D receptor's (VDR) activity was reduced, indicating a weakening of immune responses.
When we supplemented with VD in lab settings, we noticed impressive barrier-preserving effects. In fact, VD reversed the impairment caused by the infection, supporting better functioning of tight junctions within the gut lining. This ultimately led to decreased bacteria moving across the gut barrier.
Overall, our research suggests that vitamin D could be a promising treatment in addressing gut turmoil caused by foodborne infections. It appears that VD supplementation could restore gut barrier functionality, providing a new avenue for both human and animal health.
Read More
8
Vitamin D enhances immune response
The differential effects of 1,25-dihydroxyvitamin D3 on Salmonella-induced interleukin-8 and human beta-defensin-2 in intestinal epithelial cells.
We explored the effect of 1,25-dihydroxyvitamin D3, a potent form of vitamin D, on the body's response to food poisoning caused by Salmonella. The research focused on how this vitamin influences key immune proteins produced by intestinal epithelial cells, which are crucial for fighting infections.
Our findings revealed that vitamin D treatment led to decreased levels of interleukin-8, a protein that promotes inflammation, in response to Salmonella. However, it notably enhanced the production of human beta-defensin-2, an important antimicrobial peptide that helps protect against infections.
These effects seem to stem from vitamin D's influence on specific cellular pathways, indicating that it could fine-tune our immune system’s response. By bolstering anti-microbial defense while tempering excessive inflammation, vitamin D may enhance our body’s ability to fend off Salmonella infections, suggesting a potential therapeutic strategy against foodborne diseases.
Read More
User Reviews
USERS' SCORE
Good
Based on 15 Reviews
8.4
All Reviews
Positive Reviews
Negative Reviews
9
Best supplement
3 people found this helpful
This remedy for colic is effective! It tastes like oil; I use 5 drops with food, and it's the best option from birth. I can confidently say this is the best supplement that has significantly helped us.
Read More
9
Effective laxative
2 people found this helpful
My son has been constipated since starting baby food. I tried magnesium oxide, but once it was stopped, the issue returned. Since introducing this, he has been able to pass stools easily, marking a significant improvement.
Read More
9
Quick recovery noted
1 people found this helpful
Quick fix for nausea, diarrhoea, tummy ache, or even flu symptoms! This strain of bacteria is especially beneficial for children experiencing these issues. With just a couple of doses, they show noticeable improvement. It is best taken on an empty stomach a few minutes before food. The taste is tolerable, even for babies. I can guarantee the quality as its action is quite fast. Within 2-3 days of usage (as often as needed), my child felt better. I once used it on my elderly mother who suffered from severe gastroenteritis, and after one dose, she stopped vomiting. You just need to keep taking it every few hours to balance the gut bacteria.
Read More
9
Constipation resolved
1 people found this helpful
While introducing baby food, my son encountered mild constipation. However, after consistently using this supplement, the issue has cleared up entirely, and I’m pleased with the results after ten months of regular use.
Read More
9
Stomach issues resolved
1 people found this helpful
Since the age of two months, my son had been constipated and required daily cotton swab enemas. After trying this at eleven months, I noticed that, following the introduction of oatmeal as baby food, constipation has greatly improved. Moreover, I found that my son's sleep has vastly improved too—he now sleeps longer periods without waking as frequently. I wish I had discovered this sooner!
Food poisoning, also known as foodborne illness, occurs when you consume contaminated food or beverages. This contamination can result from bacteria, viruses, parasites, or chemical substances that have infected the food. Common symptoms of food poisoning include nausea, vomiting, diarrhea, abdominal cramps, and fever, which usually appear within hours or days following the consumption of contaminated food. While most cases resolve on their own within a few days, some can lead to severe complications, especially in vulnerable populations such as young children, the elderly, and individuals with weakened immune systems.
To prevent food poisoning, it's essential to practice safe food handling techniques such as washing hands, cooking food to the appropriate temperatures, and avoiding cross-contamination between raw and cooked foods. Keeping your refrigerator at the correct temperature and being mindful of expiration dates can also help reduce the risk of foodborne illnesses. If you suspect that you have food poisoning, particularly if symptoms are severe or persistent, it's important to seek medical attention.
Children's probiotics are dietary supplements specifically formulated to provide beneficial bacteria that support digestive health and the immune system in children. These probiotics contain various strains of live microorganisms, often including Lactobacillus and Bifidobacterium, which are known to help maintain a healthy balance of gut bacteria. The gut microbiome plays a crucial role in children's overall health, influencing their digestion, immune function, and even mood. Many parents turn to children's probiotics to help address issues like constipation, diarrhea, or colic, as well as to support their child’s immunity, especially during cold and flu season.
When selecting a children's probiotic, it’s essential to consider factors such as the specific strains included, the number of colony-forming units (CFUs), and whether it is tailored to your child's specific health needs. Probiotics can come in various forms, including powders, gummies, and liquids, making them easy to administer to little ones. However, it’s always advisable to consult a pediatrician before starting any new supplement regime for your child, as they can provide personalized recommendations based on the child's health history and current needs.
While children's probiotics are often touted for their potential benefits in gut health and digestion, their effectiveness in treating food poisoning specifically is not well-established. Probiotics can help restore the balance of good bacteria in the gut, particularly following antibiotic use or gastrointestinal disturbances. Some studies suggest that probiotics may reduce the duration of diarrhea in cases of infectious gastroenteritis, which can accompany food poisoning. However, it's important to note that they are not a cure and should not replace traditional treatment methods, such as hydration and rest.
If your child is experiencing symptoms of food poisoning, such as vomiting, diarrhea, or abdominal pain, it's essential to consult a healthcare professional for appropriate guidance. They can assess the situation and determine whether probiotics may be a beneficial addition to your child's recovery plan or if other treatments are necessary. Always prioritize safety and proper medical advice when it comes to food-related illnesses.
Based on user reviews, many parents have reported seeing results from this supplement fairly quickly, particularly when addressing symptoms associated with gastrointestinal issues. Users have indicated that noticeable improvement can occur within 2-3 days of consistent use, especially in cases of nausea and diarrhea. One reviewer mentioned that after just a couple of doses, their child showed significant improvement, aligning with others who experienced similar rapid relief from symptoms related to food poisoning and gut health Read Review.
In a few instances, longer-term use has also yielded benefits. For example, one user shared that after a duration of ten months using the supplement, their child achieved consistent relief from digestive issues Read Review. Although initial results can be prompt, ongoing usage may continue to support gut health and provide cumulative benefits over time, making this product a reliable choice for both immediate relief and ongoing maintenance of digestive wellness.
Scientific research supports the potential use of Vitamin D to combat food poisoning, particularly in cases caused by common pathogens like Salmonella. A study highlighted how 1,25-dihydroxyvitamin D3, an active metabolite of Vitamin D, can modulate immune responses during Salmonella infections. This research found that Vitamin D treatment resulted in reduced inflammation, evidenced by lower interleukin-8 levels, while simultaneously boosting the production of human beta-defensin-2, an antimicrobial peptide essential for fighting infections [2]. These findings suggest that Vitamin D could enhance the body’s defenses, making it a promising candidate for managing foodborne illnesses.
Additionally, another study investigated the effects of Vitamin D on gut health during infections caused by foodborne bacteria. The results demonstrated that Vitamin D supplementation could restore gut barrier function impaired by infections. The research indicated that Vitamin D helped maintain tight junctions within the gut lining, ultimately reducing bacterial translocation across the gut barrier [1]. In summary, the studies collectively point to Vitamin D not only as a potential treatment for food poisoning but also as a means to bolster our immune system against such infections.
Based on user reviews, many parents have reported significant improvements in their children's gastrointestinal symptoms after using this supplement. For instance, one user noted that their child who struggled with constipation could pass stools easily after introducing the product, highlighting a noticeable difference in their bowel movements Read Review. Another reviewer shared that their son experienced improved sleep patterns subsequent to using the supplement, which contributed to a resolution of long-standing constipation issues Read Review.
Users have also praised the supplement for alleviating a range of symptoms including colic, nausea, and tummy aches, with many experiencing rapid relief within just a couple of doses Read Review. Several parents mentioned a marked enhancement in their children's digestive health over time, with consistent use leading to regular bowel movements and overall improved well-being Read Review. While experiences vary on an individual level, the collective feedback suggests that this product may effectively support gastrointestinal health in young children.
Based on user reviews, there are several insights regarding the combination of this supplement with other substances when managing food poisoning and gastrointestinal issues. Users have enthusiastically reported that the supplement works well on its own, but some have offered suggestions for additional complementary support. For example, one user indicated that it's helpful to take the supplement on an empty stomach a few minutes before meals to maximize its effects on nausea and diarrhea, ensuring a quicker balance of gut bacteria Read Review. Additionally, users have noted that consistent dosing after initial relief serves to prevent further gastrointestinal issues, making it potentially beneficial to integrate with other dietary adjustments or supplements aimed at maintaining gut health.
Though specific combinations with other supplements weren’t widely discussed, several users emphasized that the effective outcomes they experienced with this product allowed them to manage food poisoning symptoms more easily. One reviewer even noted that it benefited an elderly relative suffering from severe gastroenteritis, indicating its potential versatility across different age groups Read Review. Overall, user feedback suggests that while the supplement is highly regarded for its efficacy on its own, incorporating it with food or possibly other supportive supplements may enhance its effectiveness in dealing with food-related gastrointestinal disruptions.
Based on user reviews, there appears to be a consensus among parents regarding the effective dosing of Children's Probiotics for treating gastrointestinal issues, including food poisoning. One user noted a significant improvement in their child's symptoms after administering a couple of doses, indicating that the probiotics are best taken on an empty stomach before meals, with favorable results typically noted within 2-3 days of consistent use Read Review. Additionally, another review highlights that the product helped alleviate symptoms quickly, suggesting the need for regular dosing to maintain gut balance Read Review.
Overall, when tackling food-related illnesses, the general recommendation from users seems to lean towards using one or two drops of the probiotic several times a day, with an emphasis on monitoring the child's reaction and adjusting based on their needs. Parents noted that making the probiotics part of their child's routine—even during times of distress—resulted in better digestive health and recovery Read Review.
9
Quick recovery noted
1 people found this helpful
Quick fix for nausea, diarrhoea, tummy ache, or even flu symptoms! This strain of bacteria is especially beneficial for children experiencing these issues. With just a couple of doses, they show noticeable improvement. It is best taken on an empty stomach a few minutes before food. The taste is tolerable, even for babies. I can guarantee the quality as its action is quite fast. Within 2-3 days of usage (as often as needed), my child felt better. I once used it on my elderly mother who suffered from severe gastroenteritis, and after one dose, she stopped vomiting. You just need to keep taking it every few hours to balance the gut bacteria.
9
Constipation resolved
1 people found this helpful
While introducing baby food, my son encountered mild constipation. However, after consistently using this supplement, the issue has cleared up entirely, and I’m pleased with the results after ten months of regular use.
9
Effective laxative
2 people found this helpful
My son has been constipated since starting baby food. I tried magnesium oxide, but once it was stopped, the issue returned. Since introducing this, he has been able to pass stools easily, marking a significant improvement.
9
Stomach issues resolved
1 people found this helpful
Since the age of two months, my son had been constipated and required daily cotton swab enemas. After trying this at eleven months, I noticed that, following the introduction of oatmeal as baby food, constipation has greatly improved. Moreover, I found that my son's sleep has vastly improved too—he now sleeps longer periods without waking as frequently. I wish I had discovered this sooner!
7.5
Prevented hospitalisation
1 people found this helpful
My child, who started nursery school, had stomach issues and was hospitalised for two weeks due to a viral infection. After being discharged, I sought this supplement to help prevent further illnesses and regulate his stomach. Initially, I gave him two drops each morning and evening, which seemed beneficial as he hasn't caught a cold since. He’s regained weight lost during hospitalisation and seems to be doing well. While I cannot pinpoint its exact effect on his gastrointestinal environment, it appears to alleviate teething discomfort and mouth inflammation, which has been encouraging. Although a bit pricey, it’s worth it for my child’s health.
9
Probiotic necessity
6 people found this helpful
The best for your child! Contains 100% reuteri, which is essential for the body. I have given it since birth after my baby was on antibiotics early on. Despite the stress of the situation, this product has worked wonders in conjunction with breastfeeding. There are no issues now, and my baby is thriving at 8 months, so I ordered a second pack as complementary foods are being introduced.
8
Vitamin D enhances immune response
The differential effects of 1,25-dihydroxyvitamin D3 on Salmonella-induced interleukin-8 and human beta-defensin-2 in intestinal epithelial cells.
We explored the effect of 1,25-dihydroxyvitamin D3, a potent form of vitamin D, on the body's response to food poisoning caused by Salmonella. The research focused on how this vitamin influences key immune proteins produced by intestinal epithelial cells, which are crucial for fighting infections.
Our findings revealed that vitamin D treatment led to decreased levels of interleukin-8, a protein that promotes inflammation, in response to Salmonella. However, it notably enhanced the production of human beta-defensin-2, an important antimicrobial peptide that helps protect against infections.
These effects seem to stem from vitamin D's influence on specific cellular pathways, indicating that it could fine-tune our immune system’s response. By bolstering anti-microbial defense while tempering excessive inflammation, vitamin D may enhance our body’s ability to fend off Salmonella infections, suggesting a potential therapeutic strategy against foodborne diseases.
9
Vitamin D aids gut health restoration
Vitamin D Reverses Disruption of Gut Epithelial Barrier Function Caused by .
We explored the effects of vitamin D (VD) on gut health during infections caused by a common foodborne bacterium. By using intestinal cells and mouse models, we looked at how this vitamin interacts with the body’s defenses and could potentially restore the gut’s protective barrier during these infections.
Our findings reveal that infections can disrupt gut barrier function and activate the immune system. In patients suffering from campylobacteriosis, we noted that the vitamin D receptor's (VDR) activity was reduced, indicating a weakening of immune responses.
When we supplemented with VD in lab settings, we noticed impressive barrier-preserving effects. In fact, VD reversed the impairment caused by the infection, supporting better functioning of tight junctions within the gut lining. This ultimately led to decreased bacteria moving across the gut barrier.
Overall, our research suggests that vitamin D could be a promising treatment in addressing gut turmoil caused by foodborne infections. It appears that VD supplementation could restore gut barrier functionality, providing a new avenue for both human and animal health.
References
Lobo de Sá FD, Backert S, Nattramilarasu PK, Mousavi S, Sandle GI, et al. Vitamin D Reverses Disruption of Gut Epithelial Barrier Function Caused by . Int J Mol Sci. 2021;22. doi:10.3390/ijms22168872
Huang FC. The differential effects of 1,25-dihydroxyvitamin D3 on Salmonella-induced interleukin-8 and human beta-defensin-2 in intestinal epithelial cells. Clin Exp Immunol. 2016;185:98. doi:10.1111/cei.12792