We investigated how vitamin D3 supplementation impacts cholesterol levels in pediatric patients with obesity. During our study, we divided 723 children into two groups: one received vitamin D3 supplements, while the other received a placebo. This allowed us to comprehensively assess the relationship between vitamin D and metabolic health, especially focusing on high cholesterol.
What we found was promising. After introducing vitamin D3 to the participants, we observed a significant drop in various lipid levels among those who received the supplements compared to those who were on the placebo. Specifically, there were notable reductions in total cholesterol, triglycerides, and low-density lipoprotein (LDL), alongside improvements in high-density lipoprotein (HDL).
Our results highlight that vitamin D3 not only boosted vitamin D levels but also positively influenced cholesterol metabolism. This suggests that supplementing with vitamin D could be a helpful strategy for managing high cholesterol, particularly in children struggling with obesity. Overall, our findings underscore the potential of vitamin D in improving metabolic health in younger populations.
Read More
8
Vitamin D improves triglycerides and HDL-C
Effect of Vitamin D Supplementation on Lipid Profile in Overweight or Obese Women: A Meta-analysis and Systematic Review of Randomized Controlled Trials.
We wanted to understand how vitamin D supplementation affects cholesterol levels, especially in women who are overweight or obese. Our analysis involved reviewing multiple randomized controlled trials, allowing us to look closely at the changes potential vitamin D can bring to lipid profiles.
We found that taking vitamin D led to significant reductions in triglyceride levels and total cholesterol. Specifically, triglycerides dropped by about 6.13 mg/dL, while total cholesterol saw a decrease of 4.45 mg/dL. Interestingly, we also noticed that vitamin D supplementation was linked to an increase in levels of high-density lipoprotein cholesterol (HDL-C), which is often referred to as the "good" cholesterol.
However, it's worth noting that despite these positive changes, vitamin D did not significantly impact low-density lipoprotein cholesterol (LDL-C), often known as the "bad" cholesterol. Therefore, while vitamin D can help with some lipid profile issues, its effect on LDL-C isn’t as pronounced.
Overall, we are encouraged by the results indicating that vitamin D can play a beneficial role in managing triglycerides and cholesterol levels among overweight or obese women, but we acknowledge that more research is needed to fully understand its effects on LDL-C.
Read More
8
Vitamin D associated with cholesterol improvement
Vitamin D Is Associated with Lipid Metabolism: A Sex- and Age-Dependent Analysis of a Large Outpatient Cohort.
Our investigation centered around the link between vitamin D levels and cholesterol, particularly focusing on high cholesterol. We analyzed data from nearly 48,000 outpatients to see how two forms of vitamin D—25-hydroxyvitamin D and 1,25-dihydroxyvitamin D—relate to various cholesterol parameters, such as LDL (the "bad" cholesterol), HDL (the "good" cholesterol), and total cholesterol levels.
We discovered that higher levels of 25(OH)D are connected with lower LDL and total cholesterol levels across the board. This relationship was especially strong among men over 50. Interestingly, the pattern varied for women; they showed a positive correlation with LDL and total cholesterol before age 50, but a negative association afterwards.
HDL levels consistently improved with higher 25(OH)D levels in all age groups, demonstrating the strongest link in postmenopausal women. However, the other form, 1,25(OH)D, only positively associated with HDL in people over 50 and didn't show significant effects on LDL or total cholesterol in any age category.
Overall, we pointed out that elevated levels of 25(OH)D can contribute to better cholesterol profiles, marked by lower levels of LDL and total cholesterol as well as higher HDL levels. This effect was particularly notable in those over 50 and postmenopausal women, highlighting the potential role of vitamin D in managing cholesterol levels.
Read More
Most Useful Reviews
9
Reduced fussiness
17 people found this helpful
Fussy baby? Buy these drops and thank me later! My NICU baby was on IV antibiotics, leaving him gassy and fussy. After switching from an expensive probiotic to these drops, I saw huge improvements. My son is no longer fussy, and his reflux is significantly better. I can't recommend them highly enough.
Read More
9
Relieved colic symptoms
4 people found this helpful
Great product, I bought it on my pediatrician's recommendation. It has significantly relieved my baby’s colic issue. Highly recommended.
Read More
9
Eased colic troubles
3 people found this helpful
Excellent! I was sceptical about this product for my daughter’s colic due to high expectations, but it pleasantly surprised me. From the first application, I noticed a wonderful effect. It truly helped us during those difficult three months of colic, and I recommend it for all mothers.
We investigated how vitamin D3 supplementation impacts cholesterol levels in pediatric patients with obesity. During our study, we divided 723 children into two groups: one received vitamin D3 supplements, while the other received a placebo. This allowed us to comprehensively assess the relationship between vitamin D and metabolic health, especially focusing on high cholesterol.
What we found was promising. After introducing vitamin D3 to the participants, we observed a significant drop in various lipid levels among those who received the supplements compared to those who were on the placebo. Specifically, there were notable reductions in total cholesterol, triglycerides, and low-density lipoprotein (LDL), alongside improvements in high-density lipoprotein (HDL).
Our results highlight that vitamin D3 not only boosted vitamin D levels but also positively influenced cholesterol metabolism. This suggests that supplementing with vitamin D could be a helpful strategy for managing high cholesterol, particularly in children struggling with obesity. Overall, our findings underscore the potential of vitamin D in improving metabolic health in younger populations.
Read More
8
Vitamin D's impact on cholesterol
A cohort study of serum 25-hydroxyvitamin D levels and the risk of hyperlipidaemia in adults.
We investigated the relationship between serum levels of vitamin D and the risk of high cholesterol, or hyperlipidemia, among adults in a prospective cohort study. This research involved collecting data over three years to understand how vitamin D might influence cholesterol levels, particularly focusing on different ranges of vitamin D sufficiency.
Our findings indicated that individuals with low vitamin D levels faced a significantly higher risk of developing hyperlipidemia. Specifically, those deficient in vitamin D had over 1.5 times the risk compared to those with adequate levels of this essential vitamin.
Additionally, a notable percentage of participants were found to have vitamin D deficiency, particularly among middle-aged and older adults. This suggests a potential link between lifestyle factors accompanying low vitamin D levels and the increased likelihood of high cholesterol.
Overall, these insights point to the promising possibility of improving cholesterol profiles through adequate vitamin D intake, but further research is likely needed to develop clear treatment pathways based solely on vitamin D supplementation.
Read More
8
Vitamin D improves triglycerides and HDL-C
Effect of Vitamin D Supplementation on Lipid Profile in Overweight or Obese Women: A Meta-analysis and Systematic Review of Randomized Controlled Trials.
We wanted to understand how vitamin D supplementation affects cholesterol levels, especially in women who are overweight or obese. Our analysis involved reviewing multiple randomized controlled trials, allowing us to look closely at the changes potential vitamin D can bring to lipid profiles.
We found that taking vitamin D led to significant reductions in triglyceride levels and total cholesterol. Specifically, triglycerides dropped by about 6.13 mg/dL, while total cholesterol saw a decrease of 4.45 mg/dL. Interestingly, we also noticed that vitamin D supplementation was linked to an increase in levels of high-density lipoprotein cholesterol (HDL-C), which is often referred to as the "good" cholesterol.
However, it's worth noting that despite these positive changes, vitamin D did not significantly impact low-density lipoprotein cholesterol (LDL-C), often known as the "bad" cholesterol. Therefore, while vitamin D can help with some lipid profile issues, its effect on LDL-C isn’t as pronounced.
Overall, we are encouraged by the results indicating that vitamin D can play a beneficial role in managing triglycerides and cholesterol levels among overweight or obese women, but we acknowledge that more research is needed to fully understand its effects on LDL-C.
Read More
8
Ergosterol may improve cholesterol levels
Impact of Daily High Ergosterol Intake for 14 Weeks in Ovariectomized Rats on Cholesterol and Vitamin D Biosynthesis Pathways.
We explored how ergosterol, a precursor of vitamin D, impacts cholesterol levels and vitamin D biosynthesis in ovariectomized (OVX) rats. Our study revealed that daily high ergosterol intake over 14 weeks significantly lowered plasma cholesterol levels, an important finding since high cholesterol can lead to various health issues.
Additionally, we found that treated OVX rats had higher levels of 7-dehydrocholesterol, a precursor to vitamin D, suggesting that ergosterol not only helps decrease cholesterol but may also promote improved vitamin D synthesis. We also observed a slight increase in the active form of vitamin D in these rats.
Perhaps most excitingly, ergosterol contributed to better bone strength, countering some of the effects of OVX-induced bone resorption. This suggests that ergosterol could be a promising option for addressing both dyslipidemia and osteoporosis in postmenopausal women, providing a dual benefit for health.
Overall, our findings support the idea that ergosterol could be an adjunct to traditional treatments for managing cholesterol and promoting vitamin D levels.
Read More
8
Vitamin D associated with cholesterol improvement
Vitamin D Is Associated with Lipid Metabolism: A Sex- and Age-Dependent Analysis of a Large Outpatient Cohort.
Our investigation centered around the link between vitamin D levels and cholesterol, particularly focusing on high cholesterol. We analyzed data from nearly 48,000 outpatients to see how two forms of vitamin D—25-hydroxyvitamin D and 1,25-dihydroxyvitamin D—relate to various cholesterol parameters, such as LDL (the "bad" cholesterol), HDL (the "good" cholesterol), and total cholesterol levels.
We discovered that higher levels of 25(OH)D are connected with lower LDL and total cholesterol levels across the board. This relationship was especially strong among men over 50. Interestingly, the pattern varied for women; they showed a positive correlation with LDL and total cholesterol before age 50, but a negative association afterwards.
HDL levels consistently improved with higher 25(OH)D levels in all age groups, demonstrating the strongest link in postmenopausal women. However, the other form, 1,25(OH)D, only positively associated with HDL in people over 50 and didn't show significant effects on LDL or total cholesterol in any age category.
Overall, we pointed out that elevated levels of 25(OH)D can contribute to better cholesterol profiles, marked by lower levels of LDL and total cholesterol as well as higher HDL levels. This effect was particularly notable in those over 50 and postmenopausal women, highlighting the potential role of vitamin D in managing cholesterol levels.
Fussy baby? Buy these drops and thank me later! My NICU baby was on IV antibiotics, leaving him gassy and fussy. After switching from an expensive probiotic to these drops, I saw huge improvements. My son is no longer fussy, and his reflux is significantly better. I can't recommend them highly enough.
Read More
9
Relieved colic symptoms
4 people found this helpful
Great product, I bought it on my pediatrician's recommendation. It has significantly relieved my baby’s colic issue. Highly recommended.
Read More
9
Eased colic troubles
3 people found this helpful
Excellent! I was sceptical about this product for my daughter’s colic due to high expectations, but it pleasantly surprised me. From the first application, I noticed a wonderful effect. It truly helped us during those difficult three months of colic, and I recommend it for all mothers.
Read More
9
Improved digestive health
2 people found this helpful
A highly effective product designed to combat colic and infant digestive discomfort, it minimises or even eliminates these issues, greatly enhancing the quality of life for newborns.
Read More
9
Significant improvement
2 people found this helpful
I am immensely grateful for Biogaia Probiotics! My baby struggled with acid reflux and colic, but after using this supplement, her symptoms improved significantly. The ingredients are safe and effective for young infants, and I highly recommend this product for alleviating their digestive issues.
High cholesterol, or hyperlipidemia, is a medical condition characterized by an elevated level of cholesterol in the bloodstream. Cholesterol is a waxy, fat-like substance that’s essential for building healthy cells, but too much of it can lead to serious health issues, including heart disease and stroke. Cholesterol is carried through the blood by lipoproteins, with two main types being low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL, often referred to as "bad" cholesterol, can lead to the buildup of plaque in the arteries, while HDL, known as "good" cholesterol, helps carry cholesterol away from the arteries and back to the liver.
Factors contributing to high cholesterol can include poor diet, lack of exercise, obesity, smoking, and genetic predisposition. Regular health screenings are crucial, as high cholesterol often presents no overt symptoms. Maintaining a heart-healthy diet rich in fruits, vegetables, whole grains, and healthy fats, coupled with regular physical activity and avoiding tobacco, can help manage cholesterol levels effectively. In some cases, medications may be necessary to control high cholesterol, so consulting with a healthcare provider is key for tailored advice.
Children's probiotics are dietary supplements specifically formulated to provide beneficial bacteria that support digestive health and the immune system in children. These probiotics contain various strains of live microorganisms, often including Lactobacillus and Bifidobacterium, which are known to help maintain a healthy balance of gut bacteria. The gut microbiome plays a crucial role in children's overall health, influencing their digestion, immune function, and even mood. Many parents turn to children's probiotics to help address issues like constipation, diarrhea, or colic, as well as to support their child’s immunity, especially during cold and flu season.
When selecting a children's probiotic, it’s essential to consider factors such as the specific strains included, the number of colony-forming units (CFUs), and whether it is tailored to your child's specific health needs. Probiotics can come in various forms, including powders, gummies, and liquids, making them easy to administer to little ones. However, it’s always advisable to consult a pediatrician before starting any new supplement regime for your child, as they can provide personalized recommendations based on the child's health history and current needs.
Based on user reviews, the timeline for seeing results from this supplement for high cholesterol can vary, but many users report noticeable changes typically within a few weeks. For instance, one review noted that it takes up to two weeks to see improvements, suggesting that patience might be needed for effective results Read Review. Another aspect to consider is that individual responses can vary significantly, and factors such as diet, lifestyle, and other personal health conditions may influence the effectiveness and timing of results.
Additionally, while some users have shared their experiences more positively, they don't specify a definitive timeframe, indicating that consistent use over time might lead to cumulative benefits. Therefore, while two weeks may be a common expectation, it would be prudent to continue monitoring your levels and maintain a regular intake of the supplement for optimal results.
Vitamin D supplementation has shown potential benefits in managing cholesterol levels according to various scientific studies. For instance, a study involving overweight or obese women indicated that vitamin D supplementation led to reductions in triglycerides and total cholesterol levels, along with an increase in high-density lipoprotein (HDL-C), the "good" cholesterol[2]. Additionally, research on children with obesity showed noteworthy improvements in cholesterol metabolism following vitamin D3 supplementation, including significant drops in total cholesterol and low-density lipoprotein (LDL) levels[4].
However, while there are promising signs regarding vitamin D's impact on cholesterol management, the results are not universally conclusive. Some studies suggest a link between low vitamin D levels and a higher risk of high cholesterol without establishing direct treatment effectiveness[1]. Furthermore, a significant study indicated that while elevated vitamin D levels might correlate with better cholesterol profiles, the direct role of vitamin D supplementation in treating high cholesterol remains underexplored and warrants further research[6]. Overall, vitamin D may contribute positively to cholesterol management, but more targeted research is necessary to define its therapeutic potential.
Based on user reviews, many parents report significant improvements in their infants’ digestive issues after using these probiotic drops. A couple of parents highlighted dramatic reductions in fussiness and colic symptoms; one noted that after switching to these drops, their previously gassy and fussy NICU baby showed large improvements in both fussiness and reflux symptoms Read Review. Another user, who initially had high expectations, was pleasantly surprised by the immediate effects, stating that the drops were effective right from the first application, helping their daughter during a difficult phase of colic Read Review.
In addition to addressing colic, several reviews mention the product's efficacy in alleviating constipation. One parent reported that their baby, who had struggled with constipation since birth, experienced significant relief and more frequent bowel movements after using the drops Read Review. Other parents echoed similar sentiments, noting improvements in their children's digestion and overall comfort Read Review. As always, individual results may vary, but the consistency of positive feedback suggests that many parents have found these drops to be beneficial in managing their infants' digestive issues.
7.5
Digestive system support
1 people found this helpful
I buy this repeatedly as it greatly benefits my child’s digestive system and helps with acne. Highly recommended from birth. I like that it contains vitamin D. It takes up to two weeks to see results, but the wait is worthwhile.
9
Reduced fussiness
17 people found this helpful
Fussy baby? Buy these drops and thank me later! My NICU baby was on IV antibiotics, leaving him gassy and fussy. After switching from an expensive probiotic to these drops, I saw huge improvements. My son is no longer fussy, and his reflux is significantly better. I can't recommend them highly enough.
9
Eased colic troubles
3 people found this helpful
Excellent! I was sceptical about this product for my daughter’s colic due to high expectations, but it pleasantly surprised me. From the first application, I noticed a wonderful effect. It truly helped us during those difficult three months of colic, and I recommend it for all mothers.
9
Relieved constipation
1 people found this helpful
My premature child has been constipated since birth. After using this product, he had significant relief, with bowel movements occurring more frequently. It's remarkable how effective it has been, leading me to make regular purchases.
9
Colic relief
1 people found this helpful
I am very satisfied with the product. Using BioGaia for my baby has made a noticeable difference in their digestive health and overall well-being. The easy-to-administer drops have alleviated colic symptoms and improved digestion. I would highly recommend BioGaia to parents seeking a safe and effective probiotic supplement for their little ones.
8
Vitamin D improves triglycerides and HDL-C
Effect of Vitamin D Supplementation on Lipid Profile in Overweight or Obese Women: A Meta-analysis and Systematic Review of Randomized Controlled Trials.
We wanted to understand how vitamin D supplementation affects cholesterol levels, especially in women who are overweight or obese. Our analysis involved reviewing multiple randomized controlled trials, allowing us to look closely at the changes potential vitamin D can bring to lipid profiles.
We found that taking vitamin D led to significant reductions in triglyceride levels and total cholesterol. Specifically, triglycerides dropped by about 6.13 mg/dL, while total cholesterol saw a decrease of 4.45 mg/dL. Interestingly, we also noticed that vitamin D supplementation was linked to an increase in levels of high-density lipoprotein cholesterol (HDL-C), which is often referred to as the "good" cholesterol.
However, it's worth noting that despite these positive changes, vitamin D did not significantly impact low-density lipoprotein cholesterol (LDL-C), often known as the "bad" cholesterol. Therefore, while vitamin D can help with some lipid profile issues, its effect on LDL-C isn’t as pronounced.
Overall, we are encouraged by the results indicating that vitamin D can play a beneficial role in managing triglycerides and cholesterol levels among overweight or obese women, but we acknowledge that more research is needed to fully understand its effects on LDL-C.
9
Vitamin D lowers cholesterol levels
Vitamin D Supplementation Reduces Hyperlipidemia and Improves Bone Mass in Pediatric Obesity.
We investigated how vitamin D3 supplementation impacts cholesterol levels in pediatric patients with obesity. During our study, we divided 723 children into two groups: one received vitamin D3 supplements, while the other received a placebo. This allowed us to comprehensively assess the relationship between vitamin D and metabolic health, especially focusing on high cholesterol.
What we found was promising. After introducing vitamin D3 to the participants, we observed a significant drop in various lipid levels among those who received the supplements compared to those who were on the placebo. Specifically, there were notable reductions in total cholesterol, triglycerides, and low-density lipoprotein (LDL), alongside improvements in high-density lipoprotein (HDL).
Our results highlight that vitamin D3 not only boosted vitamin D levels but also positively influenced cholesterol metabolism. This suggests that supplementing with vitamin D could be a helpful strategy for managing high cholesterol, particularly in children struggling with obesity. Overall, our findings underscore the potential of vitamin D in improving metabolic health in younger populations.
8
Vitamin D's impact on cholesterol
A cohort study of serum 25-hydroxyvitamin D levels and the risk of hyperlipidaemia in adults.
We investigated the relationship between serum levels of vitamin D and the risk of high cholesterol, or hyperlipidemia, among adults in a prospective cohort study. This research involved collecting data over three years to understand how vitamin D might influence cholesterol levels, particularly focusing on different ranges of vitamin D sufficiency.
Our findings indicated that individuals with low vitamin D levels faced a significantly higher risk of developing hyperlipidemia. Specifically, those deficient in vitamin D had over 1.5 times the risk compared to those with adequate levels of this essential vitamin.
Additionally, a notable percentage of participants were found to have vitamin D deficiency, particularly among middle-aged and older adults. This suggests a potential link between lifestyle factors accompanying low vitamin D levels and the increased likelihood of high cholesterol.
Overall, these insights point to the promising possibility of improving cholesterol profiles through adequate vitamin D intake, but further research is likely needed to develop clear treatment pathways based solely on vitamin D supplementation.
7
Vitamin D's link to cholesterol
Relationship between serum vitamin D levels and the atherogenic index of plasma: a study based on NHANES database 2011-2018.
We investigated the relationship between vitamin D levels and the atherogenic index of plasma (AIP), which is closely tied to cholesterol levels. Our analysis included data from 9,637 adults collected in the National Health and Nutrition Examination Survey between 2011 and 2018.
We found that higher serum vitamin D levels are linked to lower AIP values, indicating a potential benefit in managing cholesterol. This negative correlation was particularly significant among male participants, Non-Hispanic Black individuals, and those aged 40-70.
Interestingly, we observed a saturation effect, meaning that after reaching a certain level of vitamin D, additional increases didn't result in further decreases in AIP. This turning point was identified at about 8.56 nmol/L of serum vitamin D.
Overall, while our findings suggest a beneficial relationship between vitamin D and cholesterol levels, it's essential to approach this with caution since the study did not explicitly test vitamin D as a treatment for high cholesterol. Further research would be needed to establish any direct treatment implications.
References
Liu ZY, Liu S, Yao X, Wang CY, Song Y, et al. A cohort study of serum 25-hydroxyvitamin D levels and the risk of hyperlipidaemia in adults. Front Nutr. 2024;11:1492621. 10.3389/fnut.2024.1492621
Hu L, Velu P, Prabahar K, Hernández-Wolters B, Kord-Varkaneh H, et al. Effect of Vitamin D Supplementation on Lipid Profile in Overweight or Obese Women: A Meta-analysis and Systematic Review of Randomized Controlled Trials. Nutr Rev. 2025. 10.1093/nutrit/nuae226
Kuwabara N, Kanda J, Sato S, Nakagawa S. Impact of Daily High Ergosterol Intake for 14 Weeks in Ovariectomized Rats on Cholesterol and Vitamin D Biosynthesis Pathways. Biol Pharm Bull. 2025;48:39. 10.1248/bpb.b24-00536
Wang F, Bei L, Zhang X, Fu Y. Vitamin D Supplementation Reduces Hyperlipidemia and Improves Bone Mass in Pediatric Obesity. Crit Rev Immunol. 2025;45:31. 10.1615/CritRevImmunol.2024052129
Li X, Liu Y, Wang J, Chen X, Reichetzeder C, et al. Vitamin D Is Associated with Lipid Metabolism: A Sex- and Age-Dependent Analysis of a Large Outpatient Cohort. Nutrients. 2024;16. 10.3390/nu16223936
Hu T, Zhang Y, Chen Z, Su J. Relationship between serum vitamin D levels and the atherogenic index of plasma: a study based on NHANES database 2011-2018. Front Nutr. 2024;11:1468284. 10.3389/fnut.2024.1468284
Xu H, Qiu S, Lin P, Liao X, Lin Y, et al. Vitamin D has therapeutic effects on obesity and hyperandrogenemia in PCOS mouse model induced by low dose DHEA and high-fat diet. BMC Womens Health. 2024;24:601. 10.1186/s12905-024-03445-w
Sadeghi M, Momeni A, Mirsaeidi FS, Jamalian M, Amirpour A, et al. The Effect of Vitamin D Deficiency Treatment on Lipid Profile and C-reactive Protein in Patients with Ischemic Heart Disease: Double-blind Randomized Clinical Trial. Adv Biomed Res. 2024;13:79. 10.4103/abr.abr_380_23
Wang J, Shi T, Xu L, Li Y, Mi W, et al. Correlation between hyperlipidemia and serum vitamin D levels in an adult Chinese cohort. Front Nutr. 2024;11:1302260. 10.3389/fnut.2024.1302260