Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.2
USERS' SCORE
Good
Based on 4 Reviews
8.5
Supplement Facts
Serving Size: 5 Drops
Amount Per Serving
%DV
Vitamin D (as cholecalciferol)
10 mcg (400 IU)
100%
L.reuteriDSM 17938(L. reuteriProtectis®)
100 million CFU
†
Top Medical Research Studies
8
We set out to explore the connection between serum vitamin D levels and urinary tract infections (UTIs) in children. Our thorough investigation involved a systematic review and meta-analysis of various studies, including 12 case-control studies and a cross-sectional study. This comprehensive analysis incorporated data from a total of 839 children suffering from UTIs and 929 healthy controls.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
8
We set out to explore the link between vitamin D deficiency and urinary tract infections (UTIs) in children. Our research included a well-defined case-control study with children aged one to five years. We compared 82 children experiencing their first febrile UTI to 82 healthy peers.
By measuring vitamin D levels in their blood, we found that children suffering from UTIs had significantly lower levels of 25-hydroxy vitamin D. The average level in the UTI group was 24.27 ng/mL, while the control group had a healthier average of 31.97 ng/mL. Alarmingly, we discovered that 41.5% of the children with UTIs were vitamin D deficient compared to just 2.2% in the healthy group.
Our study indicates that low vitamin D levels may indeed be a risk factor for UTIs in young children. This finding sheds light on an important aspect of pediatric health that could lead to better prevention strategies for these infections.
By measuring vitamin D levels in their blood, we found that children suffering from UTIs had significantly lower levels of 25-hydroxy vitamin D. The average level in the UTI group was 24.27 ng/mL, while the control group had a healthier average of 31.97 ng/mL. Alarmingly, we discovered that 41.5% of the children with UTIs were vitamin D deficient compared to just 2.2% in the healthy group.
Our study indicates that low vitamin D levels may indeed be a risk factor for UTIs in young children. This finding sheds light on an important aspect of pediatric health that could lead to better prevention strategies for these infections.
8
Vitamin D deficiency increases UTI risk
We explored the link between vitamin D levels and late-onset urinary tract infections (UTIs) among kidney transplant recipients. Our study analyzed data from 2,207 individuals who had measurements of their vitamin D levels after transplantation.
We found that lower levels of circulating vitamin D were associated with a higher risk of developing late-onset infections. Specifically, every time the vitamin D level dropped by 5 ng/mL, the risk of infection increased by 5%. This connection was notably stronger for urinary tract infections, particularly in male recipients, showing a more than twofold increase in risk for those with vitamin D deficiency.
These findings suggest that maintaining adequate vitamin D levels could be a valuable strategy in preventing infections after kidney transplants. However, further research, including clinical trials, will be crucial to determine a clear causal relationship between vitamin D and urinary tract infections.
We found that lower levels of circulating vitamin D were associated with a higher risk of developing late-onset infections. Specifically, every time the vitamin D level dropped by 5 ng/mL, the risk of infection increased by 5%. This connection was notably stronger for urinary tract infections, particularly in male recipients, showing a more than twofold increase in risk for those with vitamin D deficiency.
These findings suggest that maintaining adequate vitamin D levels could be a valuable strategy in preventing infections after kidney transplants. However, further research, including clinical trials, will be crucial to determine a clear causal relationship between vitamin D and urinary tract infections.
Most Useful Reviews
10
Digestive improvement
20 people found this helpful
These baby drops are of very high quality, containing vitamin D as well. They helped relieve my child's colic, with noticeable improvements in digestive function. I would recommend them to everyone!
7.5
Tangible improvement noted
1 people found this helpful
High-quality, natural ingredients; the taste isn't unpleasant, and my child drinks it without issues. I administer it once a day, which is convenient as the size is manageable and the packaging is robust. The benefits are substantial, with noticeable improvements within the first week. All mediators recommended this product, and I struggled to find it for a long time.
9
Stronger immune system
The best probiotic for children from birth: BioGaia drops. This Swedish probiotic helps alleviate dysbiosis and restores gastrointestinal microflora, reducing issues such as colic, constipation, and regurgitation in infants. It strengthens the immune system as well. Although the package is small and empties quickly, we've noticed definite benefits, even when using a slightly lower dosage than recommended. Based on my paediatrician's advice and its neutral taste, it’s a great choice.
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.2
- All Researches
8
Vitamin D deficiency increases UTI risk
We explored the link between vitamin D levels and late-onset urinary tract infections (UTIs) among kidney transplant recipients. Our study analyzed data from 2,207 individuals who had measurements of their vitamin D levels after transplantation.
We found that lower levels of circulating vitamin D were associated with a higher risk of developing late-onset infections. Specifically, every time the vitamin D level dropped by 5 ng/mL, the risk of infection increased by 5%. This connection was notably stronger for urinary tract infections, particularly in male recipients, showing a more than twofold increase in risk for those with vitamin D deficiency.
These findings suggest that maintaining adequate vitamin D levels could be a valuable strategy in preventing infections after kidney transplants. However, further research, including clinical trials, will be crucial to determine a clear causal relationship between vitamin D and urinary tract infections.
We found that lower levels of circulating vitamin D were associated with a higher risk of developing late-onset infections. Specifically, every time the vitamin D level dropped by 5 ng/mL, the risk of infection increased by 5%. This connection was notably stronger for urinary tract infections, particularly in male recipients, showing a more than twofold increase in risk for those with vitamin D deficiency.
These findings suggest that maintaining adequate vitamin D levels could be a valuable strategy in preventing infections after kidney transplants. However, further research, including clinical trials, will be crucial to determine a clear causal relationship between vitamin D and urinary tract infections.
We explored the relationship between vitamin D levels and urinary tract infections (UTIs) in children. In our study, we assessed the serum vitamin D and zinc levels among two groups: 40 healthy children and 40 children suffering from UTIs, ensuring that no other health factors influenced the results.
Our findings revealed a stark difference between the groups. A staggering 80% of the children with UTIs had vitamin D deficiency, compared to only 17.5% in the healthy group. This significant gap raised an interesting question: could low vitamin D levels contribute to the likelihood of developing UTIs in children?
We also noted that low zinc levels paralleled vitamin D deficiency, with 60% of UTI patients showing zinc insufficiency compared to just 17.5% in the healthy cohort. This observation suggests that both nutrients might be crucial for maintaining a healthy immune response, particularly in young children.
Overall, our study highlights the potential importance of addressing vitamin D levels in children prone to UTIs. Supplementing with vitamin D and zinc could become a vital strategy in not only treating infections but also preventing future occurrences.
Our findings revealed a stark difference between the groups. A staggering 80% of the children with UTIs had vitamin D deficiency, compared to only 17.5% in the healthy group. This significant gap raised an interesting question: could low vitamin D levels contribute to the likelihood of developing UTIs in children?
We also noted that low zinc levels paralleled vitamin D deficiency, with 60% of UTI patients showing zinc insufficiency compared to just 17.5% in the healthy cohort. This observation suggests that both nutrients might be crucial for maintaining a healthy immune response, particularly in young children.
Overall, our study highlights the potential importance of addressing vitamin D levels in children prone to UTIs. Supplementing with vitamin D and zinc could become a vital strategy in not only treating infections but also preventing future occurrences.
8
We set out to explore the connection between serum vitamin D levels and urinary tract infections (UTIs) in children. Our thorough investigation involved a systematic review and meta-analysis of various studies, including 12 case-control studies and a cross-sectional study. This comprehensive analysis incorporated data from a total of 839 children suffering from UTIs and 929 healthy controls.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
8
We set out to explore the link between vitamin D deficiency and urinary tract infections (UTIs) in children. Our research included a well-defined case-control study with children aged one to five years. We compared 82 children experiencing their first febrile UTI to 82 healthy peers.
By measuring vitamin D levels in their blood, we found that children suffering from UTIs had significantly lower levels of 25-hydroxy vitamin D. The average level in the UTI group was 24.27 ng/mL, while the control group had a healthier average of 31.97 ng/mL. Alarmingly, we discovered that 41.5% of the children with UTIs were vitamin D deficient compared to just 2.2% in the healthy group.
Our study indicates that low vitamin D levels may indeed be a risk factor for UTIs in young children. This finding sheds light on an important aspect of pediatric health that could lead to better prevention strategies for these infections.
By measuring vitamin D levels in their blood, we found that children suffering from UTIs had significantly lower levels of 25-hydroxy vitamin D. The average level in the UTI group was 24.27 ng/mL, while the control group had a healthier average of 31.97 ng/mL. Alarmingly, we discovered that 41.5% of the children with UTIs were vitamin D deficient compared to just 2.2% in the healthy group.
Our study indicates that low vitamin D levels may indeed be a risk factor for UTIs in young children. This finding sheds light on an important aspect of pediatric health that could lead to better prevention strategies for these infections.
8
We conducted a study to investigate the relationship between vitamin D levels and urinary tract infections (UTIs) in children. This case-control research involved 80 children, aged between 1 and 12 years, who had been diagnosed with UTIs. For every child in the UTI group, we matched a control child of the same age and sex who did not have a UTI.
We measured the serum vitamin D levels using a method called ELISA. The results were telling. Our findings revealed that children with UTIs had significantly lower levels of vitamin D compared to their healthy peers. In fact, the odds of having a UTI were more than three times greater for those with low vitamin D levels.
Interestingly, we observed that this connection was particularly pronounced in female children. They showed an even higher risk of UTI when their vitamin D levels were low. As for male children, we didn't find a significant difference in vitamin D levels between those with UTIs and those without.
Our conclusions highlight a vital relationship between vitamin D deficiency and the prevalence of UTIs in children. Not only does vitamin D deficiency appear to increase the risk of UTIs, but female gender also seems to be a prominent risk factor.
We measured the serum vitamin D levels using a method called ELISA. The results were telling. Our findings revealed that children with UTIs had significantly lower levels of vitamin D compared to their healthy peers. In fact, the odds of having a UTI were more than three times greater for those with low vitamin D levels.
Interestingly, we observed that this connection was particularly pronounced in female children. They showed an even higher risk of UTI when their vitamin D levels were low. As for male children, we didn't find a significant difference in vitamin D levels between those with UTIs and those without.
Our conclusions highlight a vital relationship between vitamin D deficiency and the prevalence of UTIs in children. Not only does vitamin D deficiency appear to increase the risk of UTIs, but female gender also seems to be a prominent risk factor.
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
10
Digestive improvement
20 people found this helpful
These baby drops are of very high quality, containing vitamin D as well. They helped relieve my child's colic, with noticeable improvements in digestive function. I would recommend them to everyone!
7.5
Tangible improvement noted
1 people found this helpful
High-quality, natural ingredients; the taste isn't unpleasant, and my child drinks it without issues. I administer it once a day, which is convenient as the size is manageable and the packaging is robust. The benefits are substantial, with noticeable improvements within the first week. All mediators recommended this product, and I struggled to find it for a long time.
9
Stronger immune system
The best probiotic for children from birth: BioGaia drops. This Swedish probiotic helps alleviate dysbiosis and restores gastrointestinal microflora, reducing issues such as colic, constipation, and regurgitation in infants. It strengthens the immune system as well. Although the package is small and empties quickly, we've noticed definite benefits, even when using a slightly lower dosage than recommended. Based on my paediatrician's advice and its neutral taste, it’s a great choice.
2
No effect seen
I purchased this for my baby due to gastrointestinal issues, hoping it would normalise hard stools, but unfortunately, it did not work. Despite the high price, I expected better results but did not notice any effect. The small tube runs out quickly as well.
Frequently Asked Questions
10
Digestive improvement
20 people found this helpful
These baby drops are of very high quality, containing vitamin D as well. They helped relieve my child's colic, with noticeable improvements in digestive function. I would recommend them to everyone!
7.5
Tangible improvement noted
1 people found this helpful
High-quality, natural ingredients; the taste isn't unpleasant, and my child drinks it without issues. I administer it once a day, which is convenient as the size is manageable and the packaging is robust. The benefits are substantial, with noticeable improvements within the first week. All mediators recommended this product, and I struggled to find it for a long time.
9
Stronger immune system
The best probiotic for children from birth: BioGaia drops. This Swedish probiotic helps alleviate dysbiosis and restores gastrointestinal microflora, reducing issues such as colic, constipation, and regurgitation in infants. It strengthens the immune system as well. Although the package is small and empties quickly, we've noticed definite benefits, even when using a slightly lower dosage than recommended. Based on my paediatrician's advice and its neutral taste, it’s a great choice.
2
No effect seen
I purchased this for my baby due to gastrointestinal issues, hoping it would normalise hard stools, but unfortunately, it did not work. Despite the high price, I expected better results but did not notice any effect. The small tube runs out quickly as well.
8
Vitamin D deficiency increases UTI risk
We explored the link between vitamin D levels and late-onset urinary tract infections (UTIs) among kidney transplant recipients. Our study analyzed data from 2,207 individuals who had measurements of their vitamin D levels after transplantation.
We found that lower levels of circulating vitamin D were associated with a higher risk of developing late-onset infections. Specifically, every time the vitamin D level dropped by 5 ng/mL, the risk of infection increased by 5%. This connection was notably stronger for urinary tract infections, particularly in male recipients, showing a more than twofold increase in risk for those with vitamin D deficiency.
These findings suggest that maintaining adequate vitamin D levels could be a valuable strategy in preventing infections after kidney transplants. However, further research, including clinical trials, will be crucial to determine a clear causal relationship between vitamin D and urinary tract infections.
We found that lower levels of circulating vitamin D were associated with a higher risk of developing late-onset infections. Specifically, every time the vitamin D level dropped by 5 ng/mL, the risk of infection increased by 5%. This connection was notably stronger for urinary tract infections, particularly in male recipients, showing a more than twofold increase in risk for those with vitamin D deficiency.
These findings suggest that maintaining adequate vitamin D levels could be a valuable strategy in preventing infections after kidney transplants. However, further research, including clinical trials, will be crucial to determine a clear causal relationship between vitamin D and urinary tract infections.
We explored the relationship between vitamin D levels and urinary tract infections (UTIs) in children. In our study, we assessed the serum vitamin D and zinc levels among two groups: 40 healthy children and 40 children suffering from UTIs, ensuring that no other health factors influenced the results.
Our findings revealed a stark difference between the groups. A staggering 80% of the children with UTIs had vitamin D deficiency, compared to only 17.5% in the healthy group. This significant gap raised an interesting question: could low vitamin D levels contribute to the likelihood of developing UTIs in children?
We also noted that low zinc levels paralleled vitamin D deficiency, with 60% of UTI patients showing zinc insufficiency compared to just 17.5% in the healthy cohort. This observation suggests that both nutrients might be crucial for maintaining a healthy immune response, particularly in young children.
Overall, our study highlights the potential importance of addressing vitamin D levels in children prone to UTIs. Supplementing with vitamin D and zinc could become a vital strategy in not only treating infections but also preventing future occurrences.
Our findings revealed a stark difference between the groups. A staggering 80% of the children with UTIs had vitamin D deficiency, compared to only 17.5% in the healthy group. This significant gap raised an interesting question: could low vitamin D levels contribute to the likelihood of developing UTIs in children?
We also noted that low zinc levels paralleled vitamin D deficiency, with 60% of UTI patients showing zinc insufficiency compared to just 17.5% in the healthy cohort. This observation suggests that both nutrients might be crucial for maintaining a healthy immune response, particularly in young children.
Overall, our study highlights the potential importance of addressing vitamin D levels in children prone to UTIs. Supplementing with vitamin D and zinc could become a vital strategy in not only treating infections but also preventing future occurrences.
8
We set out to explore the connection between serum vitamin D levels and urinary tract infections (UTIs) in children. Our thorough investigation involved a systematic review and meta-analysis of various studies, including 12 case-control studies and a cross-sectional study. This comprehensive analysis incorporated data from a total of 839 children suffering from UTIs and 929 healthy controls.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
7
We examined the impact of vitamin D on the prevention of urinary tract infections (UTIs) as part of a broader review of nonantibiotic interventions. The study analyzed data from multiple randomized controlled trials, involving thousands of participants, to assess the effectiveness of vitamin D alongside other treatments.
Our findings revealed that vitamin D was part of a combination treatment known as triple therapy, which included cranberry and probiotics. While this combined approach showed benefits, isolating the individual effect of vitamin D on UTI prevention proved challenging. However, when we looked closer, we found that vitamin D did exhibit some efficacy in long-term follow-ups, specifically over a year, where it demonstrated a notable impact in reducing UTI incidents.
Overall, our exploration highlighted that while vitamin D plays a role in UTI prevention as part of a combination therapy, the evidence does not strongly support its standalone effectiveness. Therefore, those looking for UTI prevention strategies may find other nonantibiotic options, like probiotics and cranberry, to be more effective.
Our findings revealed that vitamin D was part of a combination treatment known as triple therapy, which included cranberry and probiotics. While this combined approach showed benefits, isolating the individual effect of vitamin D on UTI prevention proved challenging. However, when we looked closer, we found that vitamin D did exhibit some efficacy in long-term follow-ups, specifically over a year, where it demonstrated a notable impact in reducing UTI incidents.
Overall, our exploration highlighted that while vitamin D plays a role in UTI prevention as part of a combination therapy, the evidence does not strongly support its standalone effectiveness. Therefore, those looking for UTI prevention strategies may find other nonantibiotic options, like probiotics and cranberry, to be more effective.
References
- Yuan Z, Melamed ML, Parajuli S, Mandelbrot D, Astor BC. Association of Posttransplant Circulating 25-Hydroxyvitamin D and Late-Onset Infections Among Kidney Transplant Recipients: The Wisconsin Allograft Recipient Database (WisARD). Transpl Infect Dis. 2025. doi:10.1111/tid.70016
- Han Z, Yi X, Li J, Liao D, Ai J. Nonantibiotic prophylaxis for urinary tract infections: a network meta-analysis of randomized controlled trials. Infection. 2024. doi:10.1007/s15010-024-02357-z
- Seifollahi M, Heidarzadeh Arani M, Hoseini Shamsabadi R, Nakhaie S, Karimi Aghche M, et al. Serum Vitamin D and Zinc Levels in Children with Urinary Tract Infection without Confounding Factors: A Case-Control Study. Med J Islam Repub Iran. 2024;38:36. doi:10.47176/mjiri.38.36
- Gan Y, You S, Ying J, Mu D. The Association between Serum Vitamin D Levels and Urinary Tract Infection Risk in Children: A Systematic Review and Meta-Analysis. Nutrients. 2023;15. doi:10.3390/nu15122690
- Chidambaram S, Pasupathy U, Geminiganesan S, R D. The Association Between Vitamin D and Urinary Tract Infection in Children: A Case-Control Study. Cureus. 2022;14:e25291. doi:10.7759/cureus.25291
- Sadeghzadeh M, Khoshnevisasl P, Motamed N, Faghfouri L. The serum vitamin D levels in children with urinary tract infection: a case-control study. New Microbes New Infect. 2021;43:100911. doi:10.1016/j.nmni.2021.100911
- Qadir S, Memon S, Chohan MN, Memon Y. Frequency of Vitamin-D deficiency in children with Urinary tract infection: A descriptive cross-sectional study. Pak J Med Sci. 2021;37:1058. doi:10.12669/pjms.37.4.3896
- Muntean C, Săsăran M. Vitamin D Status and Its Role in First-Time and Recurrent Urinary Tract Infections in Children: A Case-Control Study. Children (Basel). 2021;8. doi:10.3390/children8050419
- Habibi M, Azimi S, Khoobbakht D, Roghanian P, Asadi Karam MR. Immunization with recombinant protein Ag43::UpaH with alum and 1,25(OH)2D3 adjuvants significantly protects Balb/C mice against urinary tract infection caused by uropathogenic Escherichia coli. Int Immunopharmacol. 2021;96:107638. doi:10.1016/j.intimp.2021.107638
- Li X, Yu Q, Qin F, Zhang B, Lu Y. Serum Vitamin D Level and the Risk of Urinary Tract Infection in Children: A Systematic Review and Meta-Analysis. Front Public Health. 2021;9:637529. doi:10.3389/fpubh.2021.637529
- Pirdel L, Pirdel M. A Differential Immune Modulating Role of Vitamin D in Urinary Tract Infection. Immunol Invest. 2022;51:531. doi:10.1080/08820139.2020.1845723
- Sürmeli Döven S, Erdoğan S. Vitamin D deficiency as a risk factor for renal scarring in recurrent urinary tract infections. Pediatr Int. 2021;63:295. doi:10.1111/ped.14397
- Ali SB, Perdawood D, Abdulrahman R, Al Farraj DA, Alkubaisi NA. Vitamin D deficiency as a risk factor for urinary tract infection in women at reproductive age. Saudi J Biol Sci. 2020;27:2942. doi:10.1016/j.sjbs.2020.08.008
