Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 4 Reviews
8.8
Supplement Facts
Serving Size: 1 drop (0.001 fl oz/ 0.028 ml)
Amount Per Serving
%DV
Vitamin D (as cholecalciferol)
10 mcg (400 IU)
100%
Top Medical Research Studies
8
We explored how a specific genetic variant associated with vitamin D might influence the occurrence of cold sores, also known as Herpes Simplex Labialis (HSL). Our research involved nearly 1,800 participants from the TwinsUK registry, with a focus on a group of 595 that completed both blood tests and questionnaires regarding their cold sore experiences.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
Read More
Most Useful Reviews
9.5
Reduced illness duration
Vitamin D has had a remarkable effect! It has helped straighten my child's legs, strengthen bones and boost immunity. After trying Aquadetrim and Vigantol without much success, I opted for a higher-quality vitamin D, despite the cost. Within months, my child's fontanel had closed, and after six months, their legs improved significantly, with the valgus deformity disappearing. We generally don’t use orthopedic shoes, allowing for more natural foot development. The child's head sweating ceased, skin appearances improved, and they were less frequently ill with colds. Previously, when unwell, they suffered from SARs for 7-10 days, but now it’s just 2-3 days. Even my high temperature dropped rapidly after taking vitamin D. I believe in the benefits of vitamin D wholeheartedly.
Read More
9.5
No negative effects
Vitamin D has shown a real effect! I experienced no negative side effects, whereas some mothers report issues in their reviews. Over a couple of months, the fontanel closed, and my child’s legs improved, alleviating the valgus deformity. We avoided orthopedic shoes, opting instead for summer barefoot play. The head sweating ceased, skin conditions enhanced, and the child’s SARs episodes significantly reduced. Their fever of 39 dropped to normal within a day after taking vitamin D. I also take it for colds, and I feel revitalised within days. It's widely believed that a lack of sun leads to illness, particularly in colder months. Thanks to vitamin D, we’ve stayed healthy this past year—I wholeheartedly recommend it if prescribed.
Read More
9.5
Sweating and colds resolved
One of the best D3! Previously, my son took Aquadetrim but experienced excessive sweating and frequent colds. After switching him to this vitamin D, those issues have completely resolved.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We explored how a specific genetic variant associated with vitamin D might influence the occurrence of cold sores, also known as Herpes Simplex Labialis (HSL). Our research involved nearly 1,800 participants from the TwinsUK registry, with a focus on a group of 595 that completed both blood tests and questionnaires regarding their cold sore experiences.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
From the participants surveyed, 235 reported having experienced cold sores at least once, and out of these, 160 indicated that they had recurrent episodes. While we investigated several genetic variants, including three commonly discussed in relation to cold sores, we found no significant links between these particular SNPs and the occurrence or recurrence of cold sores.
However, our analysis did reveal a noteworthy association with a genetic variation in the Vitamin D Receptor (VDR) gene. This variant was significantly correlated with both the history of cold sore outbreaks and their frequency. While this suggests a potential relationship between vitamin D-related genetics and cold sore experiences, it does not mean that vitamin D treatment has a proven direct effect on reducing these occurrences.
Overall, our findings provide an intriguing glimpse into the genetic factors that may play a role in cold sore reactivation, especially as it pertains to the VDR gene. Yet, since we didn't explore the direct effects of vitamin D supplementation, more research would be needed to conclusively determine how vitamin D treatment might influence cold sore frequency.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.8
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Reduced illness duration
Vitamin D has had a remarkable effect! It has helped straighten my child's legs, strengthen bones and boost immunity. After trying Aquadetrim and Vigantol without much success, I opted for a higher-quality vitamin D, despite the cost. Within months, my child's fontanel had closed, and after six months, their legs improved significantly, with the valgus deformity disappearing. We generally don’t use orthopedic shoes, allowing for more natural foot development. The child's head sweating ceased, skin appearances improved, and they were less frequently ill with colds. Previously, when unwell, they suffered from SARs for 7-10 days, but now it’s just 2-3 days. Even my high temperature dropped rapidly after taking vitamin D. I believe in the benefits of vitamin D wholeheartedly.
Read More
9.5
No negative effects
Vitamin D has shown a real effect! I experienced no negative side effects, whereas some mothers report issues in their reviews. Over a couple of months, the fontanel closed, and my child’s legs improved, alleviating the valgus deformity. We avoided orthopedic shoes, opting instead for summer barefoot play. The head sweating ceased, skin conditions enhanced, and the child’s SARs episodes significantly reduced. Their fever of 39 dropped to normal within a day after taking vitamin D. I also take it for colds, and I feel revitalised within days. It's widely believed that a lack of sun leads to illness, particularly in colder months. Thanks to vitamin D, we’ve stayed healthy this past year—I wholeheartedly recommend it if prescribed.
Read More
9.5
Sweating and colds resolved
One of the best D3! Previously, my son took Aquadetrim but experienced excessive sweating and frequent colds. After switching him to this vitamin D, those issues have completely resolved.
Read More
8.8
Convenient administration
Excellent! Vitamin D is crucial for overall health, and my family takes it in different dosages. I chose the drops for my son as he cannot yet swallow pills. Administering 2-3 drops in a spoonful of water after breakfast is very convenient. I can increase the dosage during a cold without any adverse reactions. One bottle lasts us a long time.
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Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Santamaria P, Bowyer RCE, Nibali L. Associations between host genetic variants and Herpes Simplex Labialis in the TwinsUK cohort. Arch Oral Biol. 2023;145:105587. doi:10.1016/j.archoralbio.2022.105587
