Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 5 Reviews
8.5
Supplement Facts
Serving Size:  1 drop (0.001 fl oz/ 0.028 ml)
Amount Per Serving
%DV
Vitamin D (as cholecalciferol)
10 mcg (400 IU)
100%

Top Medical Research Studies

We explored the effects of vitamin D (VD) on gut health during infections caused by a common foodborne bacterium. By using intestinal cells and mouse models, we looked at how this vitamin interacts with the body’s defenses and could potentially restore the gut’s protective barrier during these infections.

Our findings reveal that infections can disrupt gut barrier function and activate the immune system. In patients suffering from campylobacteriosis, we noted that the vitamin D receptor's (VDR) activity was reduced, indicating a weakening of immune responses.

When we supplemented with VD in lab settings, we noticed impressive barrier-preserving effects. In fact, VD reversed the impairment caused by the infection, supporting better functioning of tight junctions within the gut lining. This ultimately led to decreased bacteria moving across the gut barrier.

Overall, our research suggests that vitamin D could be a promising treatment in addressing gut turmoil caused by foodborne infections. It appears that VD supplementation could restore gut barrier functionality, providing a new avenue for both human and animal health.
Read More
8
Vitamin D enhances immune response
We explored the effect of 1,25-dihydroxyvitamin D3, a potent form of vitamin D, on the body's response to food poisoning caused by Salmonella. The research focused on how this vitamin influences key immune proteins produced by intestinal epithelial cells, which are crucial for fighting infections.

Our findings revealed that vitamin D treatment led to decreased levels of interleukin-8, a protein that promotes inflammation, in response to Salmonella. However, it notably enhanced the production of human beta-defensin-2, an important antimicrobial peptide that helps protect against infections.

These effects seem to stem from vitamin D's influence on specific cellular pathways, indicating that it could fine-tune our immune system’s response. By bolstering anti-microbial defense while tempering excessive inflammation, vitamin D may enhance our body’s ability to fend off Salmonella infections, suggesting a potential therapeutic strategy against foodborne diseases.
Read More

Most Useful Reviews

9.5
Healthy child benefits
Supplement for kids. The quality of Carlson is always exceptional, and I trust the brand. The ingredients are great with a neutral taste. A single drop suffices from birth, and the dosage is 400 IU. Although small in size, it lasts long. The packaging is bright and attractive. The improvements in taking D3 are immediately noticeable. My child's health has improved; there’s no sign of rickets or dysplasia. I'm very satisfied with my purchase and would definitely recommend it to others.
Read More
9
Quick vitamin improvement
Excellent! I confidently buy this company's products for my son, who has food allergies. The supplement works well; his vitamin D3 levels rose quickly. It's essential to give higher dosages as prescribed by a doctor. If you only give the recommended 400 IU, it may not be effective.
Read More
8.3
Effective vitamin D
Great quality vitamin D. I have given this to my child from birth, as my own levels were low prior to pregnancy. It has no taste and does not alter food flavours. It's straightforward to use; I adjust the dosage based on age. According to recent test results, the vitamin D levels in children are excellent, confirming it works effectively.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
  • All Researches
We explored the effects of vitamin D (VD) on gut health during infections caused by a common foodborne bacterium. By using intestinal cells and mouse models, we looked at how this vitamin interacts with the body’s defenses and could potentially restore the gut’s protective barrier during these infections.

Our findings reveal that infections can disrupt gut barrier function and activate the immune system. In patients suffering from campylobacteriosis, we noted that the vitamin D receptor's (VDR) activity was reduced, indicating a weakening of immune responses.

When we supplemented with VD in lab settings, we noticed impressive barrier-preserving effects. In fact, VD reversed the impairment caused by the infection, supporting better functioning of tight junctions within the gut lining. This ultimately led to decreased bacteria moving across the gut barrier.

Overall, our research suggests that vitamin D could be a promising treatment in addressing gut turmoil caused by foodborne infections. It appears that VD supplementation could restore gut barrier functionality, providing a new avenue for both human and animal health.
Read More
8
Vitamin D enhances immune response
We explored the effect of 1,25-dihydroxyvitamin D3, a potent form of vitamin D, on the body's response to food poisoning caused by Salmonella. The research focused on how this vitamin influences key immune proteins produced by intestinal epithelial cells, which are crucial for fighting infections.

Our findings revealed that vitamin D treatment led to decreased levels of interleukin-8, a protein that promotes inflammation, in response to Salmonella. However, it notably enhanced the production of human beta-defensin-2, an important antimicrobial peptide that helps protect against infections.

These effects seem to stem from vitamin D's influence on specific cellular pathways, indicating that it could fine-tune our immune system’s response. By bolstering anti-microbial defense while tempering excessive inflammation, vitamin D may enhance our body’s ability to fend off Salmonella infections, suggesting a potential therapeutic strategy against foodborne diseases.
Read More

User Reviews

USERS' SCORE
Good
Based on 5 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Healthy child benefits
Supplement for kids. The quality of Carlson is always exceptional, and I trust the brand. The ingredients are great with a neutral taste. A single drop suffices from birth, and the dosage is 400 IU. Although small in size, it lasts long. The packaging is bright and attractive. The improvements in taking D3 are immediately noticeable. My child's health has improved; there’s no sign of rickets or dysplasia. I'm very satisfied with my purchase and would definitely recommend it to others.
Read More
9
Quick vitamin improvement
Excellent! I confidently buy this company's products for my son, who has food allergies. The supplement works well; his vitamin D3 levels rose quickly. It's essential to give higher dosages as prescribed by a doctor. If you only give the recommended 400 IU, it may not be effective.
Read More
8.3
Effective vitamin D
Great quality vitamin D. I have given this to my child from birth, as my own levels were low prior to pregnancy. It has no taste and does not alter food flavours. It's straightforward to use; I adjust the dosage based on age. According to recent test results, the vitamin D levels in children are excellent, confirming it works effectively.
Read More
8.8
Growth observed
Hand over your analysis if in doubt; this is a good vitamin D, conveniently dosed for children. It's easy to administer a few drops. A larger dose is recommended. Initially, I gave my child evening doses instead of morning, leading to overexcitement. Before starting complementary food, I paused the vitamin D. After switching to the correct dosage, my child's hair growth improved, and there were no allergies or hyperactivity. I've reduced the dosage to one drop of 1000 IU, and I take it myself now.
Read More
6.8
Routine effect noticed
Normal Vitamin D. We have used it multiple times. It is effective. However, when adding it to food for my child, I have to wait 20 seconds for each drop to ensure it dispenses properly.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Lobo de Sá FD, Backert S, Nattramilarasu PK, Mousavi S, Sandle GI, et al. Vitamin D Reverses Disruption of Gut Epithelial Barrier Function Caused by . Int J Mol Sci. 2021;22. doi:10.3390/ijms22168872
  2. Huang FC. The differential effects of 1,25-dihydroxyvitamin D3 on Salmonella-induced interleukin-8 and human beta-defensin-2 in intestinal epithelial cells. Clin Exp Immunol. 2016;185:98. doi:10.1111/cei.12792
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