We aimed to explore the connection between Vitamin D levels and excessive daytime sleepiness in patients diagnosed with obstructive sleep apnea (OSA). In this study, we analyzed serum Vitamin D levels in a group of newly diagnosed OSA patients, dividing them into two categories: those who experienced excessive daytime sleepiness (EDS) and those who did not.
Our findings indicated that patients with EDS had significantly lower levels of Vitamin D compared to their non-somnolent counterparts. The study showed that lower Vitamin D levels correlated with higher apnea-hypopnea indices (AHI) and lower oxyhemoglobin saturation during sleep. This suggests that sleep-related hypoxia may impact Vitamin D status and contribute to sleepiness.
Moreover, our analysis indicated that lower Vitamin D levels were independent predictors of EDS. This further emphasizes the potential role of Vitamin D in managing sleep quality for these patients. In summary, our study highlights an important association between Vitamin D levels and daytime sleepiness in people with sleep apnea, suggesting that improving Vitamin D status could be beneficial for managing EDS in these individuals.
Read More
7
Vitamin D's role in sleep apnea
Associations between Vitamin D Status and Polysomnographic Parameters in Adults with Obstructive Sleep Apnea.
We explored the connection between vitamin D levels and obstructive sleep apnea (OSA) severity in a group of 262 adults who were diagnosed with OSA through polysomnography (a type of sleep study). Our aim was to understand if vitamin D deficiency could influence the severity of sleep apnea symptoms, particularly given the growing evidence linking these two health issues.
In our findings, we observed that 63% of participants had low vitamin D levels, which were associated with increased severity of OSA. The results showed a negative correlation between vitamin D levels and key sleep parameters, meaning that lower vitamin D was linked to worse apnea-hypopnea indices, which measure the frequency of breathing interruptions.
Notably, when we adjusted for various factors like age, sex, and body mass index, our analysis revealed that individuals with higher vitamin D levels had lower chances of experiencing severe OSA. Conversely, those with vitamin D deficiency were nearly three times more likely to have severe symptoms, particularly in individuals over 50 or those categorized as obese.
This study suggests that maintaining adequate vitamin D levels might be important in managing OSA severity. However, it’s essential to note that we did not specifically examine the effects of vitamin D treatment, so more research is needed to determine whether increasing vitamin D can effectively improve sleep apnea outcomes.
Overall, our work highlights the potential role of vitamin D as a modifiable factor in the complex management of obstructive sleep apnea and its symptoms.
Read More
7
Vitamin D and sleep apnea explored
Exploring the link between vitamin D deficiency and obstructive sleep apnea: A comprehensive review.
We delved into the intriguing link between vitamin D deficiency and obstructive sleep apnea (OSA). Our investigation revealed that many individuals with OSA also struggle with low vitamin D levels, no matter where they are located around the globe. This finding suggests that there may be underlying factors contributing to vitamin D deficiency beyond just insufficient sunlight exposure.
Furthermore, we observed that reduced levels of vitamin D might correlate with more severe cases of OSA. This led us to consider whether boosting vitamin D levels through supplementation could serve as a potential treatment for OSA. Notably, some studies pointed out that patients who took vitamin D supplements reported improvements in sleep quality and a decrease in the severity of their OSA symptoms.
We proposed several potential mechanisms for how vitamin D might influence OSA. These included its role in reducing inflammation and oxidative stress, improving immune function, affecting muscle function, and even involving genetic factors related to vitamin D receptors. However, we underline the need for further research to better understand these connections and to figure out the best dosages and treatment durations for vitamin D supplementation.
Read More
Most Useful Reviews
9
Reduced sweating
1 people found this helpful
A very good vitamin! My daughter used to have a sweaty head during sleep, but just a few days after starting this vitamin, that symptom has disappeared.
Read More
9
Normal sleep restored
I chose this vitamin as a cheaper alternative and have noticed my child’s sleep has returned to normal. It's important to experiment with different brands, as not all are suitable for everyone.
Read More
9
Convenient dosage
This vitamin D is excellent. I gave it to my twins aged 3, and after 4-5 days, the sweating at the back of the head during sleep ceased. Administering 3 drops in the morning with breakfast is very convenient. A single bottle lasts for 1.5 months between the two children.
We embarked on an intriguing study to see how an eight-week weight loss and lifestyle intervention could influence vitamin D levels in men suffering from obstructive sleep apnea (OSA). Our group of 89 men was split into two; one group received usual care, while the second group engaged in the lifestyle program alongside their standard treatment.
After this intervention, we observed some promising results regarding vitamin D levels. Specifically, the intervention group showed a significant increase in serum 25-hydroxyvitamin D (25(OH)D) levels, with improvements noted at both the end of the 8 weeks and six months later. Indeed, their vitamin D deficiency was potentially resolved.
Moreover, we found that these higher vitamin D levels correlated with better sleep quality, as evidenced by increased sleep efficiency and improvements in several sleep metrics, such as the apnea-hypopnea index (AHI) and oxygen desaturation index. Additionally, body composition measurements, including fat mass, also showed positive changes.
In conclusion, our findings suggest that a coordinated approach combining weight loss and lifestyle changes can be beneficial not just for vitamin D status, but also for overall health aspects related to obstructive sleep apnea.
Read More
8
Vitamin D may reduce OSA risk
Relationship of serum 25-hydroxyvitamin D, obesity with new-onset obstructive sleep apnea.
We embarked on a large-scale study to understand how vitamin D influences obstructive sleep apnea (OSA), especially in those who are obese. Analyzing data from nearly 445,000 participants from the UK Biobank, we focused on individuals who had no previous diagnosis of OSA. The key outcome was the development of new cases of OSA over an average follow-up of 12 years.
What we found was intriguing: higher serum levels of 25-hydroxyvitamin D, the main form of vitamin D in the bloodstream, were associated with a reduced risk of developing new-onset OSA, particularly in participants struggling with obesity. Those with both a body mass index (BMI) of 25 or higher and waist circumference measurements of 90 cm or more showed a significant inverse relationship. This suggests that those with these characteristics might benefit more from maintaining higher vitamin D levels.
The results indicate that while vitamin D supplementation on its own wasn't tested, our findings certainly highlight its potential role in preventing OSA, particularly in at-risk populations. It's a reminder of the importance of monitoring and maintaining adequate vitamin D levels, especially for those dealing with obesity.
Read More
7
Vitamin D3 aids OSA treatment
Unveiling the benefits of Vitamin D3 with SGLT-2 inhibitors for hypertensive obese obstructive sleep apnea patients.
We conducted a study aimed at understanding how vitamin D3 might influence obstructive sleep apnea (OSA), particularly in hypertensive, obese patients. The research carefully examined the potential benefits of combining vitamin D3 with a medication called Dapagliflozin, a type of SGLT-2 inhibitor known for its additional cardiovascular advantages.
Over 16 weeks, participants were divided into four groups: those receiving Dapagliflozin, those receiving vitamin D3, those receiving both treatments, and a control group that received no treatment. We looked at a range of health parameters, including weight, blood sugar levels, and quality of life scores, to assess the overall impact of these treatments.
Our findings revealed positive outcomes from using vitamin D3 alongside SGLT-2 inhibitors, suggesting that this combination therapy could help improve cardiac and metabolic health, as well as quality of life in patients struggling with OSA. However, we acknowledged the need for further studies to isolate the specific effects of vitamin D on sleep apnea independently from the benefits provided by the medication.
Read More
7
Vitamin D's role in sleep apnea
Sleepiness and Vitamin D Levels in Patients with Obstructive Sleep Apnea.
We aimed to explore the connection between Vitamin D levels and excessive daytime sleepiness in patients diagnosed with obstructive sleep apnea (OSA). In this study, we analyzed serum Vitamin D levels in a group of newly diagnosed OSA patients, dividing them into two categories: those who experienced excessive daytime sleepiness (EDS) and those who did not.
Our findings indicated that patients with EDS had significantly lower levels of Vitamin D compared to their non-somnolent counterparts. The study showed that lower Vitamin D levels correlated with higher apnea-hypopnea indices (AHI) and lower oxyhemoglobin saturation during sleep. This suggests that sleep-related hypoxia may impact Vitamin D status and contribute to sleepiness.
Moreover, our analysis indicated that lower Vitamin D levels were independent predictors of EDS. This further emphasizes the potential role of Vitamin D in managing sleep quality for these patients. In summary, our study highlights an important association between Vitamin D levels and daytime sleepiness in people with sleep apnea, suggesting that improving Vitamin D status could be beneficial for managing EDS in these individuals.
Read More
7
Vitamin D and sleep apnea explored
Exploring the link between vitamin D deficiency and obstructive sleep apnea: A comprehensive review.
We delved into the intriguing link between vitamin D deficiency and obstructive sleep apnea (OSA). Our investigation revealed that many individuals with OSA also struggle with low vitamin D levels, no matter where they are located around the globe. This finding suggests that there may be underlying factors contributing to vitamin D deficiency beyond just insufficient sunlight exposure.
Furthermore, we observed that reduced levels of vitamin D might correlate with more severe cases of OSA. This led us to consider whether boosting vitamin D levels through supplementation could serve as a potential treatment for OSA. Notably, some studies pointed out that patients who took vitamin D supplements reported improvements in sleep quality and a decrease in the severity of their OSA symptoms.
We proposed several potential mechanisms for how vitamin D might influence OSA. These included its role in reducing inflammation and oxidative stress, improving immune function, affecting muscle function, and even involving genetic factors related to vitamin D receptors. However, we underline the need for further research to better understand these connections and to figure out the best dosages and treatment durations for vitamin D supplementation.
A very good vitamin! My daughter used to have a sweaty head during sleep, but just a few days after starting this vitamin, that symptom has disappeared.
Read More
9
Normal sleep restored
I chose this vitamin as a cheaper alternative and have noticed my child’s sleep has returned to normal. It's important to experiment with different brands, as not all are suitable for everyone.
Read More
9
Convenient dosage
This vitamin D is excellent. I gave it to my twins aged 3, and after 4-5 days, the sweating at the back of the head during sleep ceased. Administering 3 drops in the morning with breakfast is very convenient. A single bottle lasts for 1.5 months between the two children.
Read More
2
Disrupts sleep pattern
11 people found this helpful
Take in the morning. When given in the evening, my child couldn't sleep until 3 am. If taken in the morning, it only slightly reduces daytime sleep duration.
Read More
2
Child too active
3 people found this helpful
Did not like. Firstly, it is inconvenient to administer as the bottle requires turning for a long time to dispense the drops into the child's mouth. Secondly, my child becomes overly active and agitated while taking this vitamin, which disrupts sleep. We have not found this vitamin suitable, and will now be looking for alternatives.
Sleep apnea is a common and potentially serious sleep disorder characterized by irregular breathing patterns during sleep. Individuals with sleep apnea experience episodes of disrupted or paused breathing, which can occur multiple times throughout the night. These interruptions can last a few seconds to several minutes and often lead to fragmented sleep, which may result in excessive daytime sleepiness, irritability, and difficulty concentrating. The condition can be broadly classified into two main types: obstructive sleep apnea (OSA), caused by a blockage of the upper airway, and central sleep apnea (CSA), which occurs when the brain fails to send the proper signals to the muscles that control breathing.
The diagnosis of sleep apnea typically involves a sleep study, either conducted in a sleep clinic or at home using portable monitoring devices. Treatment options vary depending on the severity of the condition but may include lifestyle changes, the use of continuous positive airway pressure (CPAP) machines, oral appliances, or even surgery in some cases. If left untreated, sleep apnea can lead to various health complications, including cardiovascular issues, metabolic disorders, and impaired cognitive function, making it essential to consult a healthcare professional if you suspect you or someone you know may be affected by this disorder.
Children's Vitamin D is a dietary supplement specifically formulated to support the health and development of children. Vitamin D is crucial for maintaining healthy bones and teeth, and it plays an essential role in the functioning of the immune system. Young children, especially those who may have limited sun exposure or dietary intake of vitamin D, are often recommended to take these supplements to ensure they receive adequate levels for optimal growth and development.
Typically, children's vitamin D supplements come in various forms such as chewable tablets, gummies, or liquid drops, making them more palatable for younger audiences. The most common form is vitamin D3 (cholecalciferol), which is considered more effective in raising vitamin D levels in the body than D2 (ergocalciferol). It's essential for parents to consult with a pediatrician before starting any supplement to determine the right dosage based on individual health needs and lifestyle factors. Proper intake of vitamin D not only supports bone health but also has been linked to other health benefits, such as improved mood and immune response, making it a valuable addition to children's wellness routines.
Based on user reviews, the time it takes to see results when using this supplement for sleep-related issues, such as Sleep Apnea, can vary. Some users report noticeable improvements in just a few days. For instance, one review indicates that after starting the supplement, their child's sweating during sleep ceased within 4-5 days (Read Review). Similarly, another user noted that their child's sleep returned to normal shortly after switching to this vitamin (Read Review).
However, results aren't uniform for everyone. A few reviewers experienced adverse effects, such as increased agitation and disrupted sleep resulting from the supplement (Read Review). This variability underscores the importance of individual experimentation with the dosage and timing of administration. Overall, while some users report quick results, others caution that finding the right fit may take longer, depending on personal responses to the supplement.
The relationship between vitamin D and obstructive sleep apnea (OSA) is emerging as a point of interest in scientific research, with findings suggesting that vitamin D may play a role in managing this condition. Several studies indicate that individuals with OSA often have low levels of vitamin D, and this deficiency might correlate with the severity of apnea symptoms. For instance, a study involving 262 adults found that those with lower vitamin D levels were nearly three times more likely to experience severe OSA symptoms, particularly among older adults and those who are obese [5]. Additionally, the link between vitamin D deficiency and excessive daytime sleepiness in patients with OSA has been noted, where lower levels of vitamin D were associated with higher apnea-hypopnea indices [3].
Moreover, research has shown that lifestyle interventions aimed at improving vitamin D levels can lead to enhanced sleep quality and reduced sleep apnea severity [2]. While some studies indicate that increasing vitamin D levels could improve health outcomes related to OSA, the precise effects of vitamin D supplementation as a standalone treatment remain to be established. Overall, while vitamin D is not confirmed as a definitive treatment for sleep apnea, there is substantial preliminary evidence supporting its potential benefits in managing the condition, warranting further exploration [4].
Based on user reviews, many individuals report significant improvements in symptoms related to sleep issues after using this vitamin. For instance, several parents noted that their children experienced a cessation of nighttime sweating within just a few days of starting the supplement. One user shared that after administering the vitamin to their twins, the sweating at the back of their heads during sleep stopped after 4-5 days (Read Review). Another parent remarked that their child's sleep returned to normal after switching to this vitamin, highlighting the positive impact it had within a short timeframe (Read Review).
However, it’s important to note that results can vary considerably among users. While some found relief, others reported negative experiences, including increased agitation and disturbed sleep. One review emphasized that, despite this vitamin being ineffective for their child, it had worked well for a relative's child, illustrating the variability of responses (Read Review). Therefore, it's recommended for users to experiment with dosage and timing while keeping in mind that individual results may differ.
Based on user reviews, there appears to be a mixed response regarding the combination of this supplement with other supplements for managing Sleep Apnea. Several parents have reported success in alleviating symptoms like nighttime sweating and improving sleep quality, suggesting that this vitamin may complement existing routines effectively (Read Review, Read Review). However, there are also accounts of adverse effects such as increased agitation and disrupted sleep when combined with other supplements or taken at night, which indicates that careful monitoring is essential (Read Review, Read Review).
Users recommend experimenting with the timing and dosage when considering this vitamin alongside other supplements. For example, one parent noted that administering the vitamin in the morning helped avoid sleep disruption, highlighting the importance of how it is incorporated into a daily routine (Read Review). Ultimately, while many users have reported positive outcomes, the variability in individual responses suggests that those looking to combine this supplement with others for Sleep Apnea should proceed with caution and under guidance when possible.
Based on user reviews, it appears that there isn't a one-size-fits-all dosage for Children's Vitamin D when it comes to addressing sleep apnea or sleep issues in children. A few users have noted positive outcomes within just a few days of administration. For instance, one reviewer mentioned that their twin children stopped sweating during sleep after taking 3 drops in the morning with breakfast (Read Review). However, another user shared a recommendation from their pediatrician to start with 4 drops for a month and then reduce to 2, indicating the importance of consulting a professional for tailoring the dosages to individual needs (Read Review).
Additionally, timing may be a critical factor; a user reported adverse effects when giving the vitamin in the evening, causing their child to struggle with sleep until 3 am, whereas taking it in the morning seemed to work better (Read Review). This indicates that finding the right dosing schedule, along with the appropriate quantity, can be essential in managing any sleep-related issues associated with Vitamin D supplementation.
9
Convenient dosage
This vitamin D is excellent. I gave it to my twins aged 3, and after 4-5 days, the sweating at the back of the head during sleep ceased. Administering 3 drops in the morning with breakfast is very convenient. A single bottle lasts for 1.5 months between the two children.
9
Normal sleep restored
I chose this vitamin as a cheaper alternative and have noticed my child’s sleep has returned to normal. It's important to experiment with different brands, as not all are suitable for everyone.
2
Child too active
3 people found this helpful
Did not like. Firstly, it is inconvenient to administer as the bottle requires turning for a long time to dispense the drops into the child's mouth. Secondly, my child becomes overly active and agitated while taking this vitamin, which disrupts sleep. We have not found this vitamin suitable, and will now be looking for alternatives.
2
Sleep disturbances noted
Unfortunately, this medicine did not work for us. My daughter was always agitated and her sleep became disturbed. I had to stop giving it. Interestingly, it worked well for my sister.
9
Reduced sweating
1 people found this helpful
A very good vitamin! My daughter used to have a sweaty head during sleep, but just a few days after starting this vitamin, that symptom has disappeared.
2
Disrupts sleep pattern
11 people found this helpful
Take in the morning. When given in the evening, my child couldn't sleep until 3 am. If taken in the morning, it only slightly reduces daytime sleep duration.
2
Improved hair growth
2 people found this helpful
The vitamins were effective; my child's hair is growing more vigorously, and there's less sweating. The paediatrician recommended administering 4 drops for a month, then reducing to 2. There was an allergy and some sleeping issues related to aquadritis.
7
Vitamin D's role in sleep apnea
Associations between Vitamin D Status and Polysomnographic Parameters in Adults with Obstructive Sleep Apnea.
We explored the connection between vitamin D levels and obstructive sleep apnea (OSA) severity in a group of 262 adults who were diagnosed with OSA through polysomnography (a type of sleep study). Our aim was to understand if vitamin D deficiency could influence the severity of sleep apnea symptoms, particularly given the growing evidence linking these two health issues.
In our findings, we observed that 63% of participants had low vitamin D levels, which were associated with increased severity of OSA. The results showed a negative correlation between vitamin D levels and key sleep parameters, meaning that lower vitamin D was linked to worse apnea-hypopnea indices, which measure the frequency of breathing interruptions.
Notably, when we adjusted for various factors like age, sex, and body mass index, our analysis revealed that individuals with higher vitamin D levels had lower chances of experiencing severe OSA. Conversely, those with vitamin D deficiency were nearly three times more likely to have severe symptoms, particularly in individuals over 50 or those categorized as obese.
This study suggests that maintaining adequate vitamin D levels might be important in managing OSA severity. However, it’s essential to note that we did not specifically examine the effects of vitamin D treatment, so more research is needed to determine whether increasing vitamin D can effectively improve sleep apnea outcomes.
Overall, our work highlights the potential role of vitamin D as a modifiable factor in the complex management of obstructive sleep apnea and its symptoms.
7
Vitamin D's role in sleep apnea
Sleepiness and Vitamin D Levels in Patients with Obstructive Sleep Apnea.
We aimed to explore the connection between Vitamin D levels and excessive daytime sleepiness in patients diagnosed with obstructive sleep apnea (OSA). In this study, we analyzed serum Vitamin D levels in a group of newly diagnosed OSA patients, dividing them into two categories: those who experienced excessive daytime sleepiness (EDS) and those who did not.
Our findings indicated that patients with EDS had significantly lower levels of Vitamin D compared to their non-somnolent counterparts. The study showed that lower Vitamin D levels correlated with higher apnea-hypopnea indices (AHI) and lower oxyhemoglobin saturation during sleep. This suggests that sleep-related hypoxia may impact Vitamin D status and contribute to sleepiness.
Moreover, our analysis indicated that lower Vitamin D levels were independent predictors of EDS. This further emphasizes the potential role of Vitamin D in managing sleep quality for these patients. In summary, our study highlights an important association between Vitamin D levels and daytime sleepiness in people with sleep apnea, suggesting that improving Vitamin D status could be beneficial for managing EDS in these individuals.
9.5
Weight loss improves vitamin D levels
Impact of weight loss and lifestyle intervention on vitamin D in men with obstructive sleep apnea: The INTERAPNEA trial.
We embarked on an intriguing study to see how an eight-week weight loss and lifestyle intervention could influence vitamin D levels in men suffering from obstructive sleep apnea (OSA). Our group of 89 men was split into two; one group received usual care, while the second group engaged in the lifestyle program alongside their standard treatment.
After this intervention, we observed some promising results regarding vitamin D levels. Specifically, the intervention group showed a significant increase in serum 25-hydroxyvitamin D (25(OH)D) levels, with improvements noted at both the end of the 8 weeks and six months later. Indeed, their vitamin D deficiency was potentially resolved.
Moreover, we found that these higher vitamin D levels correlated with better sleep quality, as evidenced by increased sleep efficiency and improvements in several sleep metrics, such as the apnea-hypopnea index (AHI) and oxygen desaturation index. Additionally, body composition measurements, including fat mass, also showed positive changes.
In conclusion, our findings suggest that a coordinated approach combining weight loss and lifestyle changes can be beneficial not just for vitamin D status, but also for overall health aspects related to obstructive sleep apnea.
7
Vitamin D and sleep apnea explored
Exploring the link between vitamin D deficiency and obstructive sleep apnea: A comprehensive review.
We delved into the intriguing link between vitamin D deficiency and obstructive sleep apnea (OSA). Our investigation revealed that many individuals with OSA also struggle with low vitamin D levels, no matter where they are located around the globe. This finding suggests that there may be underlying factors contributing to vitamin D deficiency beyond just insufficient sunlight exposure.
Furthermore, we observed that reduced levels of vitamin D might correlate with more severe cases of OSA. This led us to consider whether boosting vitamin D levels through supplementation could serve as a potential treatment for OSA. Notably, some studies pointed out that patients who took vitamin D supplements reported improvements in sleep quality and a decrease in the severity of their OSA symptoms.
We proposed several potential mechanisms for how vitamin D might influence OSA. These included its role in reducing inflammation and oxidative stress, improving immune function, affecting muscle function, and even involving genetic factors related to vitamin D receptors. However, we underline the need for further research to better understand these connections and to figure out the best dosages and treatment durations for vitamin D supplementation.
References
Loh HH, Tay SP, Koa AJ, Yong MC, Said A, et al. Unveiling the benefits of Vitamin D3 with SGLT-2 inhibitors for hypertensive obese obstructive sleep apnea patients. J Transl Med. 2025;23:296. 10.1186/s12967-025-06312-w
Vázquez-Lorente H, Herrera-Quintana L, Ruiz JR, Amaro-Gahete FJ, Carneiro-Barrera A. Impact of weight loss and lifestyle intervention on vitamin D in men with obstructive sleep apnea: The INTERAPNEA trial. Sleep Med. 2025;128:37. 10.1016/j.sleep.2025.01.011
Archontogeorgis K, Economou NT, Bargiotas P, Nena E, Voulgaris A, et al. Sleepiness and Vitamin D Levels in Patients with Obstructive Sleep Apnea. Healthcare (Basel). 2024;12. 10.3390/healthcare12060698
Yao N, Ma C, Dou R, Shen C, Yuan Y, et al. Exploring the link between vitamin D deficiency and obstructive sleep apnea: A comprehensive review. J Sleep Res. 2024;33:e14166. 10.1111/jsr.14166
Kechribari I, Kontogianni MD, Georgoulis M, Lamprou K, Perraki E, et al. Associations between Vitamin D Status and Polysomnographic Parameters in Adults with Obstructive Sleep Apnea. Life (Basel). 2024;14. 10.3390/life14020275
Zhang Y, Zhang Y, Ye Z, Zhou C, Yang S, et al. Relationship of serum 25-hydroxyvitamin D, obesity with new-onset obstructive sleep apnea. Int J Obes (Lond). 2024;48:218. 10.1038/s41366-023-01402-5
Locci C, Ruiu A, Saderi L, Sotgiu G, Bassu S, et al. Relationships between 25-Hydroxyvitamin D Levels and Obstructive Sleep Apnea Severity in Children: An Observational Study. J Clin Med. 2023;12. 10.3390/jcm12031242