5/20/2025
Last update
5/20/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 20 Researches
7
USERS' SCORE
Good
Based on 4 Reviews
8.6
Supplement Facts
Serving Size: 2 Soft Gels
Amount Per Serving
%DV
Calories
30
Total Fat
2.5 g
3%**
Cholesterol
<5 mg
1%
Protein
<1 g
Vitamin E (as natural d-alpha tocopherol)
13.4 mg
89%
Norwegian Fish Oil
2.5 g
†
Total Omega-3 Fatty Acids*
1,600 mg
†
EPA (Eicosapentaenoic Acid)*
800 mg
†
DHA (Docosahexaenoic Acid)*
600 mg
†
Top Medical Research Studies
9
We embarked on a study to find out how dietary eicosapentaenoic acid (EPA) could help children suffering from atopic dermatitis, a common form of eczema. In a randomized triple-blind clinical trial, 48 children with this condition were divided into two groups—one received 250 mg of EPA twice daily, while the other received a placebo for four weeks.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
Read More
8
In a controlled trial, we assessed how docosahexaenoic acid (DHA)—an omega-3 fatty acid—affects atopic eczema. Fifty-three patients, aged 18 to 40, were randomly assigned to receive either 5.4 grams of DHA daily or an isoenergetic control comprising saturated fatty acids for eight weeks. This double-blind setup helped ensure that neither the participants nor the researchers knew who received which treatment, thereby reducing bias in the results.
Throughout the study, we measured the severity of eczema using the SCORAD index at multiple intervals. Our findings showed that DHA supplementation led to a notable improvement in eczema symptoms, with patients experiencing a significant decrease in their SCORAD scores. This contrasted with the control group, which did not show similar improvements. Notably, we also found that DHA reduced certain immune responses linked to eczema, indicating its potential role in managing this condition.
Given these encouraging results, it appears that DHA could be an effective dietary addition for people suffering from atopic eczema. However, further research with a larger participant pool is necessary to confirm these findings and fully understand the benefits of DHA on this skin condition.
Throughout the study, we measured the severity of eczema using the SCORAD index at multiple intervals. Our findings showed that DHA supplementation led to a notable improvement in eczema symptoms, with patients experiencing a significant decrease in their SCORAD scores. This contrasted with the control group, which did not show similar improvements. Notably, we also found that DHA reduced certain immune responses linked to eczema, indicating its potential role in managing this condition.
Given these encouraging results, it appears that DHA could be an effective dietary addition for people suffering from atopic eczema. However, further research with a larger participant pool is necessary to confirm these findings and fully understand the benefits of DHA on this skin condition.
Read More
We examined how dietary factors, particularly docosahexaenoic acid (DHA), influence the prevalence of atopic eczema among pregnant Japanese females. In a study involving 1,002 participants, we gathered data through a detailed diet history questionnaire, focusing on their intake of various fatty acids and the occurrence of atopic eczema.
Our findings revealed that DHA intake was significantly linked to a reduced rate of atopic eczema both currently and after the age of 18. However, we did not find consistent evidence supporting the idea that n-3 and n-6 polyunsaturated fatty acids, as well as total fat and other types of dietary fat, had a meaningful effect on eczema.
While the study encourages the inclusion of DHA in the diet during pregnancy, it also highlights the complexity of dietary impacts on allergic conditions like eczema. Overall, we observed a noteworthy association between higher DHA intake and lower prevalence rates of eczema in this group, suggesting that it could be a beneficial addition to the diets of pregnant women.
Our findings revealed that DHA intake was significantly linked to a reduced rate of atopic eczema both currently and after the age of 18. However, we did not find consistent evidence supporting the idea that n-3 and n-6 polyunsaturated fatty acids, as well as total fat and other types of dietary fat, had a meaningful effect on eczema.
While the study encourages the inclusion of DHA in the diet during pregnancy, it also highlights the complexity of dietary impacts on allergic conditions like eczema. Overall, we observed a noteworthy association between higher DHA intake and lower prevalence rates of eczema in this group, suggesting that it could be a beneficial addition to the diets of pregnant women.
Read More
Most Useful Reviews
10
Eczema improvement
1 people found this helpful
I started taking these omega 3 supplements due to an unbearably itchy eczema flare-up. After researching the underlying causes of eczema, I decided to give these vitamins a try. WOW!! Not only is my eczema almost nonexistent, but my facial skin has cleared up, and my hair is growing quicker as well. I have always been hesitant with fish oils due to fish burps causing me to vomit in the past, but these have no fishy aftertaste. I am so impressed!! Highly recommended.
Read More
9
Eczema relief
I bought this for my 18-year-old daughter to take in the winter. She has eczema on her hands, and when she takes omega and fish oil, the aggravations subside. This omega is of very high quality, with no allergic reactions; my daughter enjoys taking it. I recommend it for purchase.
Read More
9
Skin condition improvement
In addition to the quality of the ingredients and the overall health benefits, it improved the condition of my skin. I have eczema, and after a month of taking it, the peeling disappeared. 👍🏼
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 20 Researches
7
- All Researches
9
We embarked on a study to find out how dietary eicosapentaenoic acid (EPA) could help children suffering from atopic dermatitis, a common form of eczema. In a randomized triple-blind clinical trial, 48 children with this condition were divided into two groups—one received 250 mg of EPA twice daily, while the other received a placebo for four weeks.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
Read More
8
We examined the relationship between maternal polyunsaturated fatty acids (PUFA) during pregnancy and the risk of allergies, including eczema, in their children within the first two years of life.
In our study with 573 mother-infant pairs, we found that higher levels of certain fatty acids, especially arachidonic acid and omega-3 PUFA, were associated with a reduced risk of allergies in children.
This trend was notably stronger for children whose mothers had a history of allergies. Overall, our research suggests that maternal PUFA intake might play a protective role against eczema and other allergic conditions.
In our study with 573 mother-infant pairs, we found that higher levels of certain fatty acids, especially arachidonic acid and omega-3 PUFA, were associated with a reduced risk of allergies in children.
This trend was notably stronger for children whose mothers had a history of allergies. Overall, our research suggests that maternal PUFA intake might play a protective role against eczema and other allergic conditions.
Read More
8
EPA-E improves eczema-like symptoms
We explored how eicosapentaenoic acid ethyl ester (EPA-E), a component of omega-3 fish oil, affects atopic dermatitis-like symptoms in mice. This study showed that EPA-E could improve skin barrier issues and reduce itching in mice with conditions similar to human eczema.
We observed that the treatment helped restore important lipids in the skin, known as ceramides. These results suggest that EPA-E may offer a promising approach to treat eczema in people, but further testing is needed.
We observed that the treatment helped restore important lipids in the skin, known as ceramides. These results suggest that EPA-E may offer a promising approach to treat eczema in people, but further testing is needed.
Read More
8
We investigated how fish consumption during pregnancy and infancy influences allergic conditions in children. Our analysis included a range of studies, revealing that while mothers eating fish during pregnancy didn't seem to lower allergy risks, infants consuming fish in their first year notably reduced eczema occurrences.
Specifically, we found a reduced risk of eczema and allergic rhinitis in those who consumed fish early in life. This indicates that introducing fish to infants' diets may offer important allergy protection.
Overall, while maternal intake showed no significant benefits, early fish consumption appears promising for reducing eczema.
Specifically, we found a reduced risk of eczema and allergic rhinitis in those who consumed fish early in life. This indicates that introducing fish to infants' diets may offer important allergy protection.
Overall, while maternal intake showed no significant benefits, early fish consumption appears promising for reducing eczema.
Read More
8
We investigated how oral fatty acids and carbohydrates influence eczema symptoms. In a pilot study with OVA-sensitized mice, those fed a diet rich in arachidonic acid/docosahexaenoic acid (AA/DHA) and galactooligosaccharides/polydextrose (GOS/PDX) showed pronounced skin improvement.
The mice demonstrated reduced skin inflammation and improved skin barrier function. Specifically, the combination of AA/DHA and GOS/PDX yielded the most benefits. These findings suggest dietary additions may effectively support humans dealing with atopic eczema.
The mice demonstrated reduced skin inflammation and improved skin barrier function. Specifically, the combination of AA/DHA and GOS/PDX yielded the most benefits. These findings suggest dietary additions may effectively support humans dealing with atopic eczema.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
10
Eczema improvement
1 people found this helpful
I started taking these omega 3 supplements due to an unbearably itchy eczema flare-up. After researching the underlying causes of eczema, I decided to give these vitamins a try. WOW!! Not only is my eczema almost nonexistent, but my facial skin has cleared up, and my hair is growing quicker as well. I have always been hesitant with fish oils due to fish burps causing me to vomit in the past, but these have no fishy aftertaste. I am so impressed!! Highly recommended.
Read More
9
Eczema relief
I bought this for my 18-year-old daughter to take in the winter. She has eczema on her hands, and when she takes omega and fish oil, the aggravations subside. This omega is of very high quality, with no allergic reactions; my daughter enjoys taking it. I recommend it for purchase.
Read More
9
Skin condition improvement
In addition to the quality of the ingredients and the overall health benefits, it improved the condition of my skin. I have eczema, and after a month of taking it, the peeling disappeared. 👍🏼
Read More
7.5
Eczema and dryness relief
I really love Omega 3 from Carlson; in my opinion, it’s the best on Eicherb. It helps me fight eczema and moisturises my skin. My hair looks gorgeous, and after experiencing eye dryness post-vision correction, I no longer need drops; my eyes are now comfortable while watching TV. I take 1 capsule twice a day for 3 months, followed by a month break! All health!!
Read More
Frequently Asked Questions
9
Skin condition improvement
In addition to the quality of the ingredients and the overall health benefits, it improved the condition of my skin. I have eczema, and after a month of taking it, the peeling disappeared. 👍🏼
9
Eczema relief
I bought this for my 18-year-old daughter to take in the winter. She has eczema on her hands, and when she takes omega and fish oil, the aggravations subside. This omega is of very high quality, with no allergic reactions; my daughter enjoys taking it. I recommend it for purchase.
7.5
Eczema and dryness relief
I really love Omega 3 from Carlson; in my opinion, it’s the best on Eicherb. It helps me fight eczema and moisturises my skin. My hair looks gorgeous, and after experiencing eye dryness post-vision correction, I no longer need drops; my eyes are now comfortable while watching TV. I take 1 capsule twice a day for 3 months, followed by a month break! All health!!
10
Eczema improvement
1 people found this helpful
I started taking these omega 3 supplements due to an unbearably itchy eczema flare-up. After researching the underlying causes of eczema, I decided to give these vitamins a try. WOW!! Not only is my eczema almost nonexistent, but my facial skin has cleared up, and my hair is growing quicker as well. I have always been hesitant with fish oils due to fish burps causing me to vomit in the past, but these have no fishy aftertaste. I am so impressed!! Highly recommended.
7
We investigated the effects of docosahexaenoic acid (DHA), a type of omega-3 fatty acid, on the incidence of eczema in infants. Our study involved 145 pregnant women who had allergies or family histories of allergies. They participated in a randomized, placebo-controlled trial where some received daily supplements of DHA during pregnancy and breastfeeding, while others received a placebo.
We found that infants whose mothers took DHA experienced a lower prevalence of eczema related to immunoglobulin E (IgE). Specifically, only 8% of infants in the DHA group developed IgE-associated eczema compared to a concerning 24% in the placebo group, marking a significant difference.
This suggests that maternal omega-3 supplementation, particularly with DHA, could play a beneficial role in reducing the risk of eczema in infants with a family history of allergies. Thus, incorporating omega-3 fatty acids in a mother’s diet during pregnancy and lactation may be a simple yet effective strategy to help protect babies from developing eczema.
We found that infants whose mothers took DHA experienced a lower prevalence of eczema related to immunoglobulin E (IgE). Specifically, only 8% of infants in the DHA group developed IgE-associated eczema compared to a concerning 24% in the placebo group, marking a significant difference.
This suggests that maternal omega-3 supplementation, particularly with DHA, could play a beneficial role in reducing the risk of eczema in infants with a family history of allergies. Thus, incorporating omega-3 fatty acids in a mother’s diet during pregnancy and lactation may be a simple yet effective strategy to help protect babies from developing eczema.
7
Omega-3’s role in allergy prevention
We explored the potential benefits of omega-3 fatty acids found in fish oils during pregnancy to see if they could decrease the risk of allergic diseases in children. Our findings indicate that increased fish oil intake may indeed reduce the prevalence and severity of atopic eczema within the first year of life.
However, while there are some positive associations, the results from various studies are inconsistent. There’s no clear consensus on the effectiveness of omega-3s in preventing allergies across all children. Thus, more research is needed to confirm these findings and fortify strategies for preventing allergic conditions.
However, while there are some positive associations, the results from various studies are inconsistent. There’s no clear consensus on the effectiveness of omega-3s in preventing allergies across all children. Thus, more research is needed to confirm these findings and fortify strategies for preventing allergic conditions.
8
EPA-E improves eczema-like symptoms
We explored how eicosapentaenoic acid ethyl ester (EPA-E), a component of omega-3 fish oil, affects atopic dermatitis-like symptoms in mice. This study showed that EPA-E could improve skin barrier issues and reduce itching in mice with conditions similar to human eczema.
We observed that the treatment helped restore important lipids in the skin, known as ceramides. These results suggest that EPA-E may offer a promising approach to treat eczema in people, but further testing is needed.
We observed that the treatment helped restore important lipids in the skin, known as ceramides. These results suggest that EPA-E may offer a promising approach to treat eczema in people, but further testing is needed.
9
We embarked on a study to find out how dietary eicosapentaenoic acid (EPA) could help children suffering from atopic dermatitis, a common form of eczema. In a randomized triple-blind clinical trial, 48 children with this condition were divided into two groups—one received 250 mg of EPA twice daily, while the other received a placebo for four weeks.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
8
In a controlled trial, we assessed how docosahexaenoic acid (DHA)—an omega-3 fatty acid—affects atopic eczema. Fifty-three patients, aged 18 to 40, were randomly assigned to receive either 5.4 grams of DHA daily or an isoenergetic control comprising saturated fatty acids for eight weeks. This double-blind setup helped ensure that neither the participants nor the researchers knew who received which treatment, thereby reducing bias in the results.
Throughout the study, we measured the severity of eczema using the SCORAD index at multiple intervals. Our findings showed that DHA supplementation led to a notable improvement in eczema symptoms, with patients experiencing a significant decrease in their SCORAD scores. This contrasted with the control group, which did not show similar improvements. Notably, we also found that DHA reduced certain immune responses linked to eczema, indicating its potential role in managing this condition.
Given these encouraging results, it appears that DHA could be an effective dietary addition for people suffering from atopic eczema. However, further research with a larger participant pool is necessary to confirm these findings and fully understand the benefits of DHA on this skin condition.
Throughout the study, we measured the severity of eczema using the SCORAD index at multiple intervals. Our findings showed that DHA supplementation led to a notable improvement in eczema symptoms, with patients experiencing a significant decrease in their SCORAD scores. This contrasted with the control group, which did not show similar improvements. Notably, we also found that DHA reduced certain immune responses linked to eczema, indicating its potential role in managing this condition.
Given these encouraging results, it appears that DHA could be an effective dietary addition for people suffering from atopic eczema. However, further research with a larger participant pool is necessary to confirm these findings and fully understand the benefits of DHA on this skin condition.
8
We investigated how fish consumption during pregnancy and infancy influences allergic conditions in children. Our analysis included a range of studies, revealing that while mothers eating fish during pregnancy didn't seem to lower allergy risks, infants consuming fish in their first year notably reduced eczema occurrences.
Specifically, we found a reduced risk of eczema and allergic rhinitis in those who consumed fish early in life. This indicates that introducing fish to infants' diets may offer important allergy protection.
Overall, while maternal intake showed no significant benefits, early fish consumption appears promising for reducing eczema.
Specifically, we found a reduced risk of eczema and allergic rhinitis in those who consumed fish early in life. This indicates that introducing fish to infants' diets may offer important allergy protection.
Overall, while maternal intake showed no significant benefits, early fish consumption appears promising for reducing eczema.
References
- Jia Y, Huang Y, Wang H, Jiang H. Effect of Prenatal Omega-3 Polyunsaturated Fatty Acid Supplementation on Childhood Eczema: A Systematic Review and Meta-Analysis. Int Arch Allergy Immunol. 2023;184:21. 10.1159/000526366
- Peng S, Du Z, He Y, Zhao F, Chen Y, et al. Association of Maternal Erythrocyte PUFA during Pregnancy with Offspring Allergy in the Chinese Population. Nutrients. 2022;14. 10.3390/nu14112312
- Øien T, Schjelvaag A, Storrø O, Johnsen R, Simpson MR. Fish Consumption at One Year of Age Reduces the Risk of Eczema, Asthma and Wheeze at Six Years of Age. Nutrients. 2019;11. 10.3390/nu11091969
- Fujii M, Ohyanagi C, Kawaguchi N, Matsuda H, Miyamoto Y, et al. Eicosapentaenoic acid ethyl ester ameliorates atopic dermatitis-like symptoms in special diet-fed hairless mice, partly by restoring covalently bound ceramides in the stratum corneum. Exp Dermatol. 2018;27:837. 10.1111/exd.13507
- Miles EA, Calder PC. Can Early Omega-3 Fatty Acid Exposure Reduce Risk of Childhood Allergic Disease?. Nutrients. 2017;9. 10.3390/nu9070784
- Zhang GQ, Liu B, Li J, Luo CQ, Zhang Q, et al. Fish intake during pregnancy or infancy and allergic outcomes in children: A systematic review and meta-analysis. Pediatr Allergy Immunol. 2017;28:152. 10.1111/pai.12648
- Gunaratne AW, Makrides M, Collins CT. Maternal prenatal and/or postnatal n-3 long chain polyunsaturated fatty acids (LCPUFA) supplementation for preventing allergies in early childhood. Cochrane Database Syst Rev. 2015;2015:CD010085. 10.1002/14651858.CD010085.pub2
- Chisaguano AM, Montes R, Castellote AI, Morales E, Júlvez J, et al. Elaidic, vaccenic, and rumenic acid status during pregnancy: association with maternal plasmatic LC-PUFAs and atopic manifestations in infants. Pediatr Res. 2014;76:470. 10.1038/pr.2014.119
- Makrides M, Gunaratne AW, Collins CT. Dietary n-3 LC-PUFA during the perinatal period as a strategy to minimize childhood allergic disease. Nestle Nutr Inst Workshop Ser. 2013;77:155. 10.1159/000351398
- Weise C, Ernst D, van Tol EA, Worm M. Dietary polyunsaturated fatty acids and non-digestible oligosaccharides reduce dermatitis in mice. Pediatr Allergy Immunol. 2013;24:361. 10.1111/pai.12073
- Montes R, Chisaguano AM, Castellote AI, Morales E, Sunyer J, et al. Fatty-acid composition of maternal and umbilical cord plasma and early childhood atopic eczema in a Spanish cohort. Eur J Clin Nutr. 2013;67:658. 10.1038/ejcn.2013.68
- D'Vaz N, Meldrum SJ, Dunstan JA, Lee-Pullen TF, Metcalfe J, et al. Fish oil supplementation in early infancy modulates developing infant immune responses. Clin Exp Allergy. 2012;42:1206. 10.1111/j.1365-2222.2012.04031.x
- Palmer DJ, Sullivan T, Gold MS, Prescott SL, Heddle R, et al. Effect of n-3 long chain polyunsaturated fatty acid supplementation in pregnancy on infants' allergies in first year of life: randomised controlled trial. BMJ. 2012;344:e184. 10.1136/bmj.e184
- Kunitsugu I, Okuda M, Murakami N, Hashimoto M, Yamanishi R, et al. Self-reported seafood intake and atopy in Japanese school-aged children. Pediatr Int. 2012;54:233. 10.1111/j.1442-200X.2011.03542.x
- Furuhjelm C, Warstedt K, Fagerås M, Fälth-Magnusson K, Larsson J, et al. Allergic disease in infants up to 2 years of age in relation to plasma omega-3 fatty acids and maternal fish oil supplementation in pregnancy and lactation. Pediatr Allergy Immunol. 2011;22:505. 10.1111/j.1399-3038.2010.01096.x
- Sato A, Sato G, Yabuki A, Ogawa Y, Nemoto H, et al. Ameliorative effects of squid phospholipids from Todarodes pacificus on atopic dermatitis-like lesions in NC/Nga mice. Arch Dermatol Res. 2025;317:239. 10.1007/s00403-024-03773-9
- Mirrahimi B, Moazemi M, Eslami N, Jamshidi E, Mir M, et al. Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial. J Pediatr Pharmacol Ther. 2023;28:29. 10.5863/1551-6776-28.1.29
- Furuhjelm C, Warstedt K, Larsson J, Fredriksson M, Böttcher MF, et al. Fish oil supplementation in pregnancy and lactation may decrease the risk of infant allergy. Acta Paediatr. 2009;98:1461. 10.1111/j.1651-2227.2009.01355.x
- Miyake Y, Sasaki S, Tanaka K, Ohya Y, Matsunaga I, et al. Relationship between dietary fat and fish intake and the prevalence of atopic eczema in pregnant Japanese females: baseline data from the Osaka Maternal and Child Health Study. Asia Pac J Clin Nutr. 2008;17:612.
- Koch C, Dölle S, Metzger M, Rasche C, Jungclas H, et al. Docosahexaenoic acid (DHA) supplementation in atopic eczema: a randomized, double-blind, controlled trial. Br J Dermatol. 2008;158:786. 10.1111/j.1365-2133.2007.08430.x
