5/18/2025
Last update
5/18/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 30 Researches
7.1
USERS' SCORE
Good
Based on 2 Reviews
8.4
Supplement Facts
Serving Size: 1 Teaspoon (5 ml)
Amount Per Serving
%DV
Calories
40
Total Fat
4.5 g
6%**
Saturated Fat
0.5 g
3%**
Cholesterol
15 mg
5%
Vitamin A (from cod liver oil and retinyl palmitate)
255 mcg RAE(850 IU)
28%
Vitamin D (from cod liver oil and cholecalciferol)
10 mcg (400 IU)
50%
Vitamin E (as d-alpha tocopherol)
6.7 mg
45%
Norwegian Cod Liver Oil
4.6 g
†
Total Omega-3 Fatty Acids*
1,100 mg
†
DHA (Docosahexaenoic Acid)*
500 mg
†
EPA (Eicosapentaenoic Acid)*
370 mg
†
DPA (Docosapentaenoic Acid)*
50 mg
†
Top Medical Research Studies
9
We aimed to understand how dietary intake of docosahexaenoic acid (DHA) relates to asthma in children. This investigation was based on a substantial group of 14,727 participants from the National Health and Nutrition Examination Survey (NHANES), which provided a comprehensive view of dietary habits and health outcomes over nearly two decades.
In our findings, we observed that asthma was reported in about 15.38% of the participants. Interestingly, we found a notable negative association between DHA intake and asthma prevalence. Specifically, children who consumed higher levels of DHA showed a lower likelihood of having asthma, with the odds especially favorable for boys, children aged 5 to 12 years, and those whose mothers smoked during pregnancy.
The data indicated that DHA, along with other omega-3 fatty acids like eicosapentaenoic acid (EPA), can play a protective role against childhood asthma. These findings suggest that encouraging a diet rich in these healthy fats could be beneficial in reducing asthma risk in young children, particularly among specific groups at greater risk.
In our findings, we observed that asthma was reported in about 15.38% of the participants. Interestingly, we found a notable negative association between DHA intake and asthma prevalence. Specifically, children who consumed higher levels of DHA showed a lower likelihood of having asthma, with the odds especially favorable for boys, children aged 5 to 12 years, and those whose mothers smoked during pregnancy.
The data indicated that DHA, along with other omega-3 fatty acids like eicosapentaenoic acid (EPA), can play a protective role against childhood asthma. These findings suggest that encouraging a diet rich in these healthy fats could be beneficial in reducing asthma risk in young children, particularly among specific groups at greater risk.
Read More
9
Eicosapentaenoic acid improves asthma
We compared how different types of forage affected asthma in Thoroughbred racehorses. Our focus was on assessing dust exposure, airway health, and the presence of eicosapentaenoic acid (EPA), an omega-3 fatty acid known for its anti-inflammatory properties. The horses were randomly assigned to three diets: dry hay, steamed hay, or haylage for a period of six weeks.
Throughout the study, we observed that horses fed steamed hay and haylage had significantly lower dust exposure compared to those that consumed dry hay. Interestingly, those on the haylage diet not only showed reduced levels of neutrophils in their bronchoalveolar lavage fluid, indicating better airway health, but they also had an increase in the ratio of anti-inflammatory to pro-inflammatory lipids, particularly EPA.
In fact, the horses on haylage had higher ratios of eicosapentaenoic acid compared to both their baseline measurements and horses on the other diets. This suggests that incorporating haylage could be beneficial for managing asthma symptoms in racehorses. Overall, it appears that haylage may help improve respiratory health by reducing inflammation linked to asthma through its higher anti-inflammatory lipid profile.
Throughout the study, we observed that horses fed steamed hay and haylage had significantly lower dust exposure compared to those that consumed dry hay. Interestingly, those on the haylage diet not only showed reduced levels of neutrophils in their bronchoalveolar lavage fluid, indicating better airway health, but they also had an increase in the ratio of anti-inflammatory to pro-inflammatory lipids, particularly EPA.
In fact, the horses on haylage had higher ratios of eicosapentaenoic acid compared to both their baseline measurements and horses on the other diets. This suggests that incorporating haylage could be beneficial for managing asthma symptoms in racehorses. Overall, it appears that haylage may help improve respiratory health by reducing inflammation linked to asthma through its higher anti-inflammatory lipid profile.
Read More
8
We explored the connection between maternal supplementation with omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFA) during pregnancy and the risk of asthma or wheeze in children. By analyzing data from eight randomized controlled trials involving over 3,000 mother-infant pairs, we aimed to clarify whether these supplements could provide a protective effect against respiratory issues in offspring.
Our findings indicate that perinatal supplementation with n-3 LC-PUFA may indeed lower the likelihood of asthma and wheezing in children. Notably, the research suggested that higher doses of these fatty acids could yield even better protective effects.
While the evidence appears promising, we recognize the need for further studies to solidify the link between n-3 LC-PUFA intake during pregnancy and the prevention of asthma in children. It's clear that understanding this relationship could have significant implications for maternal and child health.
Our findings indicate that perinatal supplementation with n-3 LC-PUFA may indeed lower the likelihood of asthma and wheezing in children. Notably, the research suggested that higher doses of these fatty acids could yield even better protective effects.
While the evidence appears promising, we recognize the need for further studies to solidify the link between n-3 LC-PUFA intake during pregnancy and the prevention of asthma in children. It's clear that understanding this relationship could have significant implications for maternal and child health.
Read More
Most Useful Reviews
9
Effective for asthma
2 people found this helpful
Asthma. My son used it for asthma, which he has struggled with for years. After using it at night, he said he felt much better and would take it daily.
Read More
7.5
Breathing improved
15 people found this helpful
Unexpected results. This may sound odd, but I've dealt with dry eyes, asthma, and sensitive skin for years. I discovered that my gut health is likely linked to these issues. After using Carlson cod liver oil, my breathing improved immediately. Researching vitamin A and D's effects on my lungs revealed a connection to my asthma issues. I initially purchased it for skin and dry eyes but was pleasantly surprised by the benefits for my asthma.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 30 Researches
7.1
- All Researches
9.5
DHA-derived lipid mediators aid asthma
We explored the potential of lipid mediators derived from docosahexaenoic acid (DHA) in treating allergic asthma using a well-established ovalbumin (OVA) model in mice. The treatment comprised a mix of lipid mediators, including 17S-monohydroxy DHA, resolvin D5, and protectin DX. Through this investigation, we aimed to better understand how these components could alleviate asthma symptoms.
Our findings indicated that administering these lipid mediators significantly reduced key features of allergic asthma. We observed a decrease in inflammatory cell infiltration, particularly in eosinophils, and a drop in the levels of inflammation-related cytokines. Furthermore, treatment with the lipid mediators helped mitigate airway remodeling and oxidative stress, indicating a return to near-normal conditions for the mice.
Notably, the lipid mediators led to a remarkable drop in inflammatory markers such as interleukin-6 and tumor necrosis factor-α, signaling a positive response. We also witnessed an improvement in the lung's oxidative stress status, as shown by increased antioxidant activities and reduced harmful substances.
Collectively, our study suggests that lipid mediators from DHA could represent a promising therapeutic avenue for asthma treatment, particularly by protecting lung tissues from inflammation and oxidative damage.
Our findings indicated that administering these lipid mediators significantly reduced key features of allergic asthma. We observed a decrease in inflammatory cell infiltration, particularly in eosinophils, and a drop in the levels of inflammation-related cytokines. Furthermore, treatment with the lipid mediators helped mitigate airway remodeling and oxidative stress, indicating a return to near-normal conditions for the mice.
Notably, the lipid mediators led to a remarkable drop in inflammatory markers such as interleukin-6 and tumor necrosis factor-α, signaling a positive response. We also witnessed an improvement in the lung's oxidative stress status, as shown by increased antioxidant activities and reduced harmful substances.
Collectively, our study suggests that lipid mediators from DHA could represent a promising therapeutic avenue for asthma treatment, particularly by protecting lung tissues from inflammation and oxidative damage.
Read More
9.5
LCPUFA supplementation's impact on asthma
We explored how chronic asthma affects the levels of specific long-chain polyunsaturated fatty acids (LCPUFAs) in the body and whether supplementation could help rebalance these levels. In our study, mice were sensitized to house dust mite extract to simulate allergic asthma and were then fed either a normal diet, eicosapentaenoic acid (EPA), or a specific combination of LCPUFAs, including docosahexaenoic acid (DHA), over a period of 24 days.
What we observed was quite intriguing. Allergic asthma indeed altered the fatty acid profiles in both blood and lung tissue of the mice. However, when we looked at the effects of our specific combination of n-3 and n-6 LCPUFAs, we found that it completely restored the altered profiles in lung tissue, unlike EPA alone. This suggests that a tailored combination of these fatty acids, which includes DHA, may be highly effective in managing the inflammatory processes associated with asthma.
Thus, our findings highlight the potential of combined LCPUFA supplementation as a meaningful approach to alleviate asthma-related inflammation and improve overall respiratory health.
What we observed was quite intriguing. Allergic asthma indeed altered the fatty acid profiles in both blood and lung tissue of the mice. However, when we looked at the effects of our specific combination of n-3 and n-6 LCPUFAs, we found that it completely restored the altered profiles in lung tissue, unlike EPA alone. This suggests that a tailored combination of these fatty acids, which includes DHA, may be highly effective in managing the inflammatory processes associated with asthma.
Thus, our findings highlight the potential of combined LCPUFA supplementation as a meaningful approach to alleviate asthma-related inflammation and improve overall respiratory health.
Read More
9
We aimed to understand how dietary intake of docosahexaenoic acid (DHA) relates to asthma in children. This investigation was based on a substantial group of 14,727 participants from the National Health and Nutrition Examination Survey (NHANES), which provided a comprehensive view of dietary habits and health outcomes over nearly two decades.
In our findings, we observed that asthma was reported in about 15.38% of the participants. Interestingly, we found a notable negative association between DHA intake and asthma prevalence. Specifically, children who consumed higher levels of DHA showed a lower likelihood of having asthma, with the odds especially favorable for boys, children aged 5 to 12 years, and those whose mothers smoked during pregnancy.
The data indicated that DHA, along with other omega-3 fatty acids like eicosapentaenoic acid (EPA), can play a protective role against childhood asthma. These findings suggest that encouraging a diet rich in these healthy fats could be beneficial in reducing asthma risk in young children, particularly among specific groups at greater risk.
In our findings, we observed that asthma was reported in about 15.38% of the participants. Interestingly, we found a notable negative association between DHA intake and asthma prevalence. Specifically, children who consumed higher levels of DHA showed a lower likelihood of having asthma, with the odds especially favorable for boys, children aged 5 to 12 years, and those whose mothers smoked during pregnancy.
The data indicated that DHA, along with other omega-3 fatty acids like eicosapentaenoic acid (EPA), can play a protective role against childhood asthma. These findings suggest that encouraging a diet rich in these healthy fats could be beneficial in reducing asthma risk in young children, particularly among specific groups at greater risk.
Read More
9
We investigated the potential of Maresin-2, derived from docosahexaenoic acid (DHA), as a treatment for asthma in a mouse model. In our experiment, we compared the effects of Maresin-2 to a standard treatment, dexamethasone, by administering it to mice with asthma induced by ovalbumin and aluminum hydroxide.
Both treatments showed a reduction in airway inflammation and mucus production. We measured the number of inflammatory cells and levels of inflammatory cytokines in biological samples from the mice. Additionally, we looked at markers of oxidative stress and specific proteins related to inflammation. Interestingly, both Maresin-2 and dexamethasone appeared to lower oxidative stress while inhibiting the activation of the NLRP3 inflammasome, which plays a role in the body's immune response.
Overall, our findings suggest that Maresin-2 can effectively alleviate symptoms of asthma, similarly to the established treatment dexamethasone. This points towards Maresin-2 being a potential therapeutic option for those suffering from asthma, helping to reduce inflammation and the overall immune response.
Both treatments showed a reduction in airway inflammation and mucus production. We measured the number of inflammatory cells and levels of inflammatory cytokines in biological samples from the mice. Additionally, we looked at markers of oxidative stress and specific proteins related to inflammation. Interestingly, both Maresin-2 and dexamethasone appeared to lower oxidative stress while inhibiting the activation of the NLRP3 inflammasome, which plays a role in the body's immune response.
Overall, our findings suggest that Maresin-2 can effectively alleviate symptoms of asthma, similarly to the established treatment dexamethasone. This points towards Maresin-2 being a potential therapeutic option for those suffering from asthma, helping to reduce inflammation and the overall immune response.
Read More
9
Eicosapentaenoic acid improves asthma
We compared how different types of forage affected asthma in Thoroughbred racehorses. Our focus was on assessing dust exposure, airway health, and the presence of eicosapentaenoic acid (EPA), an omega-3 fatty acid known for its anti-inflammatory properties. The horses were randomly assigned to three diets: dry hay, steamed hay, or haylage for a period of six weeks.
Throughout the study, we observed that horses fed steamed hay and haylage had significantly lower dust exposure compared to those that consumed dry hay. Interestingly, those on the haylage diet not only showed reduced levels of neutrophils in their bronchoalveolar lavage fluid, indicating better airway health, but they also had an increase in the ratio of anti-inflammatory to pro-inflammatory lipids, particularly EPA.
In fact, the horses on haylage had higher ratios of eicosapentaenoic acid compared to both their baseline measurements and horses on the other diets. This suggests that incorporating haylage could be beneficial for managing asthma symptoms in racehorses. Overall, it appears that haylage may help improve respiratory health by reducing inflammation linked to asthma through its higher anti-inflammatory lipid profile.
Throughout the study, we observed that horses fed steamed hay and haylage had significantly lower dust exposure compared to those that consumed dry hay. Interestingly, those on the haylage diet not only showed reduced levels of neutrophils in their bronchoalveolar lavage fluid, indicating better airway health, but they also had an increase in the ratio of anti-inflammatory to pro-inflammatory lipids, particularly EPA.
In fact, the horses on haylage had higher ratios of eicosapentaenoic acid compared to both their baseline measurements and horses on the other diets. This suggests that incorporating haylage could be beneficial for managing asthma symptoms in racehorses. Overall, it appears that haylage may help improve respiratory health by reducing inflammation linked to asthma through its higher anti-inflammatory lipid profile.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective for asthma
2 people found this helpful
Asthma. My son used it for asthma, which he has struggled with for years. After using it at night, he said he felt much better and would take it daily.
Read More
7.5
Breathing improved
15 people found this helpful
Unexpected results. This may sound odd, but I've dealt with dry eyes, asthma, and sensitive skin for years. I discovered that my gut health is likely linked to these issues. After using Carlson cod liver oil, my breathing improved immediately. Researching vitamin A and D's effects on my lungs revealed a connection to my asthma issues. I initially purchased it for skin and dry eyes but was pleasantly surprised by the benefits for my asthma.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Currie C, Framroze B, Singh D, Lea S, Bjerknes C, et al. Assessing the Anti-Inflammatory Effects of an Orally Dosed Enzymatically Liberated Fish Oil in a House Dust Model of Allergic Asthma. Biomedicines. 2022;10. 10.3390/biomedicines10102574
- Jiang L, Brumpton B, Langhammer A, Chen Y, Mai XM. Intake of multivitamin supplements and incident asthma in Norwegian adults: the HUNT study. ERJ Open Res. 2015;1.
- Mai XM, Langhammer A, Chen Y, Camargo CA. Cod liver oil intake and incidence of asthma in Norwegian adults--the HUNT study. Thorax. 2013;68:25. 10.1136/thoraxjnl-2012-202061
- Hughes AM, Lucas RM, Ponsonby AL, Chapman C, Coulthard A, et al. The role of latitude, ultraviolet radiation exposure and vitamin D in childhood asthma and hayfever: an Australian multicenter study. Pediatr Allergy Immunol. 2011;22:327. 10.1111/j.1399-3038.2010.01099.x
- Laerum BN, Wentzel-Larsen T, Gulsvik A, Omenaas E, Gíslason T, et al. Relationship of fish and cod oil intake with adult asthma. Clin Exp Allergy. 2007;37:1616.
- Su Y, Choi HS, Kwon SK, Han Y, Cho SC, et al. Lipid mediators obtained from docosahexaenoic acid by soybean lipoxygenase alleviate ovalbumin‑induced allergic asthma in mice by reducing airway inflammation and oxidative stress. Mol Med Rep. 2025;31. 10.3892/mmr.2025.13451
- Keenan K, Walton S, Mbayiwa K, Akande L, Cherian A, et al. Short Report: Exploring the Effect of Prenatal Fatty Acid Supplementation on Wheeze and Asthma in Black American Children. J Asthma Allergy. 2024;17:929. 10.2147/JAA.S474009
- Liu G, Ye H, Cheng Q, Zhao J, Ma C, et al. The association of polyunsaturated fatty acids and asthma: a cross-sectional study. J Health Popul Nutr. 2023;42:91. 10.1186/s41043-023-00435-w
- Heires AJ, Samuelson D, Villageliu D, Nordgren TM, Romberger DJ. Agricultural dust derived bacterial extracellular vesicle mediated inflammation is attenuated by DHA. Sci Rep. 2023;13:2767. 10.1038/s41598-023-29781-9
- Jia Y, Huang Y, Wang H, Jiang H. A dose-response meta-analysis of the association between the maternal omega-3 long-chain polyunsaturated fatty acids supplement and risk of asthma/wheeze in offspring. BMC Pediatr. 2022;22:422. 10.1186/s12887-022-03421-z
- Yu CX, Shi ZA, Ou GC, Chen XJ, Liu Q, et al. Maresin-2 alleviates allergic airway inflammation in mice by inhibiting the activation of NLRP3 inflammasome, Th2 type immune response and oxidative stress. Mol Immunol. 2022;146:78. 10.1016/j.molimm.2022.03.118
- Obara K, Inaba R, Kawakita M, De Dios Regadera M, Uetake T, et al. Docosahexaenoic Acid Selectively Suppresses U46619- and PGF-Induced Contractions in Guinea Pig Tracheal Smooth Muscles. Biol Pharm Bull. 2022;45:240. 10.1248/bpb.b21-00905
- Adjibade M, Davisse-Paturet C, Bernard JY, Adel-Patient K, Divaret-Chauveau A, et al. Enrichment of infant formula with long-chain polyunsaturated fatty acids and risk of infection and allergy in the nationwide ELFE birth cohort. Allergy. 2022;77:1522. 10.1111/all.15137
- Ulu A, Burr A, Heires AJ, Pavlik J, Larsen T, et al. A high docosahexaenoic acid diet alters lung inflammation and recovery following repetitive exposure to aqueous organic dust extracts. J Nutr Biochem. 2021;97:108797. 10.1016/j.jnutbio.2021.108797
- Miyata J, Yokokura Y, Moro K, Arai H, Fukunaga K, et al. 12/15-Lipoxygenase Regulates IL-33-Induced Eosinophilic Airway Inflammation in Mice. Front Immunol. 2021;12:687192. 10.3389/fimmu.2021.687192
- Talaei M, Sdona E, Calder PC, Jones LR, Emmett PM, et al. Intake of -3 polyunsaturated fatty acids in childhood, genotype and incident asthma. Eur Respir J. 2021;58. 10.1183/13993003.03633-2020
- Stoodley I, Garg M, Scott H, Macdonald-Wicks L, Berthon B, et al. Higher Omega-3 Index Is Associated with Better Asthma Control and Lower Medication Dose: A Cross-Sectional Study. Nutrients. 2019;12. 10.3390/nu12010074
- Sordillo JE, Rifas-Shiman SL, Switkowski K, Coull B, Gibson H, et al. Prenatal oxidative balance and risk of asthma and allergic disease in adolescence. J Allergy Clin Immunol. 2019;144:1534. 10.1016/j.jaci.2019.07.044
- Fussbroich D, Zimmermann K, Göpel A, Eickmeier O, Trischler J, et al. A specific combined long-chain polyunsaturated fatty acid supplementation reverses fatty acid profile alterations in a mouse model of chronic asthma. Lipids Health Dis. 2019;18:16. 10.1186/s12944-018-0947-6
- Höglund N, Nieminen P, Mustonen AM, Käkelä R, Tollis S, et al. Fatty acid fingerprints in bronchoalveolar lavage fluid and its extracellular vesicles reflect equine asthma severity. Sci Rep. 2023;13:9821. 10.1038/s41598-023-36697-x
- Olave CJ, Ivester KM, Couetil LL, Burgess J, Park JH, et al. Effects of low-dust forages on dust exposure, airway cytology, and plasma omega-3 concentrations in Thoroughbred racehorses: A randomized clinical trial. J Vet Intern Med. 2023;37:338. 10.1111/jvim.16598
- Miles EA, Childs CE, Calder PC. Long-Chain Polyunsaturated Fatty Acids (LCPUFAs) and the Developing Immune System: A Narrative Review. Nutrients. 2021;13. 10.3390/nu13010247
- Fussbroich D, Colas RA, Eickmeier O, Trischler J, Jerkic SP, et al. A combination of LCPUFA ameliorates airway inflammation in asthmatic mice by promoting pro-resolving effects and reducing adverse effects of EPA. Mucosal Immunol. 2020;13:481. 10.1038/s41385-019-0245-2
- Abreu SC, Lopes-Pacheco M, da Silva AL, Xisto DG, de Oliveira TB, et al. Eicosapentaenoic Acid Enhances the Effects of Mesenchymal Stromal Cell Therapy in Experimental Allergic Asthma. Front Immunol. 2018;9:1147. 10.3389/fimmu.2018.01147
- Magnusson J, Ekström S, Kull I, Håkansson N, Nilsson S, et al. Polyunsaturated fatty acids in plasma at 8 years and subsequent allergic disease. J Allergy Clin Immunol. 2018;142:510. 10.1016/j.jaci.2017.09.023
- Lee DI, Kang SA, Md A, Jeong UC, Jin F, et al. Sea Cucumber Lipid-Soluble Extra Fraction Prevents Ovalbumin-Induced Allergic Airway Inflammation. J Med Food. 2018;21:21. 10.1089/jmf.2017.3994
- Bian X, Sun B, Zheng P, Li N, Wu JL. Derivatization enhanced separation and sensitivity of long chain-free fatty acids: Application to asthma using targeted and non-targeted liquid chromatography-mass spectrometry approach. Anal Chim Acta. 2017;989:59. 10.1016/j.aca.2017.08.009
- Mochimaru T, Fukunaga K, Miyata J, Matsusaka M, Masaki K, et al. 12-OH-17,18-Epoxyeicosatetraenoic acid alleviates eosinophilic airway inflammation in murine lungs. Allergy. 2018;73:369. 10.1111/all.13297
- Bisgaard H, Stokholm J, Chawes BL, Vissing NH, Bjarnadóttir E, et al. Fish Oil-Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring. N Engl J Med. 2016;375:2530. 10.1056/NEJMoa1503734
- Khaddaj-Mallat R, Hiram R, Sirois C, Sirois M, Rizcallah E, et al. MAG-DPA curbs inflammatory biomarkers and pharmacological reactivity in cytokine-triggered hyperresponsive airway models. Pharmacol Res Perspect. 2016;4:e00263. 10.1002/prp2.263
