We explored the impact of vitamin D3 levels on bone pain that patients experience after undergoing unicompartmental knee arthroplasty (UKA). The study involved 240 participants who were divided into three groups based on their vitamin D status—some received treatment before surgery, some after, and others had normal levels to begin with.
By administering vitamin D3 in three doses, we aimed to see if correcting deficiencies could alleviate post-operative bone pain. Throughout the recovery period, we measured pain levels using the visual analog scale at various intervals after the surgery.
Our findings clearly demonstrated that patients who corrected their vitamin D3 deficiency before surgery reported significantly better pain control after the operation compared to those who were treated afterwards or those who started with adequate levels. This highlights the importance of testing and addressing vitamin D status prior to orthopedic procedures, showing that it is a modifiable risk factor affecting recovery.
Read More
8
Calcium's role in bone pain unclear
In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution.
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
Read More
9
Effectiveness of calcitriol combination therapy
Clinical efficacy and outcomes of calcitriol combined with bisphosphonates in the treatment of postmenopausal osteoporosis: A quasi-experimental study.
We conducted an insightful study to analyze how combining calcitriol, a form of vitamin D, with bisphosphonates affects bone pain in postmenopausal women suffering from osteoporosis. This quasi-experimental approach allowed us to compare two groups: one treated with calcitriol alone and the other with the combination treatment.
Our findings highlighted that adding bisphosphonates to calcitriol significantly alleviated bone pain among the participants. We observed improved evaluations of joint pain through the Visual Analogue Scale/Score, indicating that patients felt much better post-treatment. Furthermore, the combination therapy enhanced the patients' overall daily living capabilities and positively influenced bone metabolism and density.
Overall, our results suggest that calcitriol combined with bisphosphonates is effective in not just relieving pain but also supporting the long-term health of bones in postmenopausal women. This approach may pave the way for improved treatment strategies for osteoporosis in this demographic.
Read More
Most Useful Reviews
9
Improved bone density
6 people found this helpful
Better with slow release. Since switching from regular Citracal, I've felt better absorption throughout the day, crucial for my osteoporosis. My parathyroid surgeon recommended Citracal, and I noticed my bone density has improved, all while managing without Reclast. No broken bones now, thankfully.
Read More
9
Eliminated bone pain
2 people found this helpful
This calcium has significantly helped my mother after chemotherapy. Her osteoporosis worsened, causing bone pain, but after she started taking calcium, the pains disappeared. It also helped my sister with her own arm pain, and she can now raise her arms effortlessly.
Read More
10
Increased bone growth
1 people found this helpful
This calcium truly works! Both my husband and I take it, and our dentist has noticed significant bone growth. After just six months, my bone condition improved enough for me to receive a dental implant. Very satisfied with this calcium.
We explored the impact of vitamin D3 levels on bone pain that patients experience after undergoing unicompartmental knee arthroplasty (UKA). The study involved 240 participants who were divided into three groups based on their vitamin D status—some received treatment before surgery, some after, and others had normal levels to begin with.
By administering vitamin D3 in three doses, we aimed to see if correcting deficiencies could alleviate post-operative bone pain. Throughout the recovery period, we measured pain levels using the visual analog scale at various intervals after the surgery.
Our findings clearly demonstrated that patients who corrected their vitamin D3 deficiency before surgery reported significantly better pain control after the operation compared to those who were treated afterwards or those who started with adequate levels. This highlights the importance of testing and addressing vitamin D status prior to orthopedic procedures, showing that it is a modifiable risk factor affecting recovery.
Read More
9
Effectiveness of calcitriol combination therapy
Clinical efficacy and outcomes of calcitriol combined with bisphosphonates in the treatment of postmenopausal osteoporosis: A quasi-experimental study.
We conducted an insightful study to analyze how combining calcitriol, a form of vitamin D, with bisphosphonates affects bone pain in postmenopausal women suffering from osteoporosis. This quasi-experimental approach allowed us to compare two groups: one treated with calcitriol alone and the other with the combination treatment.
Our findings highlighted that adding bisphosphonates to calcitriol significantly alleviated bone pain among the participants. We observed improved evaluations of joint pain through the Visual Analogue Scale/Score, indicating that patients felt much better post-treatment. Furthermore, the combination therapy enhanced the patients' overall daily living capabilities and positively influenced bone metabolism and density.
Overall, our results suggest that calcitriol combined with bisphosphonates is effective in not just relieving pain but also supporting the long-term health of bones in postmenopausal women. This approach may pave the way for improved treatment strategies for osteoporosis in this demographic.
Read More
8
Case study on JPD treatment
Juvenile paget's disease in an Iranian kindred with vitamin D deficiency and novel homozygous TNFRSF11B mutation.
We explored a unique case of a 3-year-old Iranian girl with Juvenile Paget's disease (JPD) linked to a new mutation and vitamin D deficiency. This rare condition led to her experiencing significant bone pain, fractures, and deformities from an early age.
Our findings revealed that she had a unique mutation in the TNFRSF11B gene, which contributes to OPG deficiency. Remarkably, she showed improvement following treatment with oral vitamin D and intravenous pamidronate. This case highlights both the impact of genetic factors and the importance of vitamin D in managing JPD effectively.
Read More
8
Vitamin D reduces fracture risk
Association Between 25-hydroxyvitamin D Status and New Vertebral Fractures Post Percutaneous Vertebral Augmentation in Patients During Postmenopause: A Retrospective Case-control Study.
We investigated the connection between vitamin D levels and the risk of new vertebral fractures in postmenopausal women who had undergone percutaneous vertebral augmentation. Through a retrospective case-control study involving patients aged 50 and older, we analyzed records to categorize participants into groups based on whether they experienced refractures and how serum levels of 25-hydroxyvitamin D (25[OH]D) influenced these outcomes.
Our findings revealed that low levels of serum 25(OH)D are linked to an increased risk of new vertebral fractures in these patients. What's noteworthy is that vitamin D plays a crucial role in maintaining bone health, and adequate levels can help reduce the likelihood of subsequent fractures after surgery. This underscores the potential importance of vitamin D supplementation for patients recovering from vertebral augmentation.
In conclusion, ensuring that patients receive appropriate vitamin D intake might be pivotal in preventing further bone pain and fractures following surgery. By addressing vitamin D deficiency, we could significantly improve bone health outcomes and enhance the quality of life for postmenopausal women recovering from vertebral fractures.
Read More
8
Calcium's role in bone pain unclear
In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution.
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
Read More
User Reviews
USERS' SCORE
Good
Based on 14 Reviews
8.2
All Reviews
Positive Reviews
Negative Reviews
9
Improved bone density
6 people found this helpful
Better with slow release. Since switching from regular Citracal, I've felt better absorption throughout the day, crucial for my osteoporosis. My parathyroid surgeon recommended Citracal, and I noticed my bone density has improved, all while managing without Reclast. No broken bones now, thankfully.
Read More
9
Eliminated bone pain
2 people found this helpful
This calcium has significantly helped my mother after chemotherapy. Her osteoporosis worsened, causing bone pain, but after she started taking calcium, the pains disappeared. It also helped my sister with her own arm pain, and she can now raise her arms effortlessly.
Read More
10
Increased bone growth
1 people found this helpful
This calcium truly works! Both my husband and I take it, and our dentist has noticed significant bone growth. After just six months, my bone condition improved enough for me to receive a dental implant. Very satisfied with this calcium.
Read More
9
Strengthened bones
A good medication prescribed by my doctor to bolster my bones, especially due to my osteoporosis.
Read More
9
Significant pain relief
This supplement truly works for my bone pain. My knee used to hurt significantly, even waking me at night. I added calcium along with turmeric, boswellia, and collagen. It's a sustained-release formula, which I prefer. After one can, my knee pain improved tremendously; calcium is surely beneficial.
Bone pain is a discomfort or ache that originates within the bones themselves and can range from mild to severe. It is different from muscle or joint pain, as it directly affects the skeletal structure. Bone pain can be caused by a variety of factors, including injuries, medical conditions such as osteoarthritis or osteoporosis, infections, or tumors. Symptoms may vary depending on the underlying cause but often include a dull, penetrating ache that may worsen with movement or pressure.
If you're experiencing persistent bone pain, it’s essential to consult with a healthcare professional for a proper diagnosis and treatment plan. Imaging tests like X-rays, MRI, or CT scans may be utilized to determine the root cause of the pain. Treatment can vary widely, ranging from medications to alleviate pain and inflammation to physical therapy or, in some cases, surgical interventions. Understanding the underlying cause is crucial to effectively managing bone pain and ensuring the best path to recovery.
Calcium Plus Vitamin D is a dietary supplement that combines calcium, an essential mineral vital for maintaining strong bones and teeth, with Vitamin D, a nutrient that enhances calcium absorption in the body. This combination is particularly beneficial for individuals looking to support their bone health, especially those at risk for osteoporosis or conditions that lead to decreased bone density. Calcium plays a key role in various bodily functions, including muscle contraction and nerve signaling, while Vitamin D aids in the regulation of calcium levels within the blood and helps promote overall immune function.
Many formulations of Calcium Plus Vitamin D are available in various forms, including tablets, capsules, and chewables, catering to different preferences and dietary needs. When considering adding a calcium and vitamin D supplement to your daily routine, it's essential to consult with a healthcare professional to ensure it's appropriate for your specific health requirements and to determine the right dosage. A balanced diet combined with regular sunlight exposure can also help maintain adequate calcium and vitamin D levels without the need for supplementation. However, for individuals who have limited sun exposure or have dietary restrictions, such supplements can provide a convenient and effective way to support bone health.
Calcium and Vitamin D are essential nutrients that play a significant role in maintaining bone health. Calcium is a primary component of bones, while Vitamin D is crucial for calcium absorption in the body. Therefore, ensuring adequate intake of both can help strengthen bones and may alleviate bone pain related to deficiencies. If your bone pain is due to conditions such as osteoporosis or osteomalacia, supplementing with Calcium Plus Vitamin D may help in managing symptoms and improving overall bone strength.
However, it's important to consult a healthcare professional before starting any supplementation, as bone pain can arise from various underlying causes that may not be related to nutrient deficiencies. In some cases, excess calcium can lead to other health issues, so professional guidance is essential. Remember that while supplements can be beneficial, they are most effective when combined with a balanced diet and a healthy lifestyle that includes weight-bearing exercises.
Based on user reviews, the time it takes to see results from this calcium supplement for bone pain varies among individuals, with many reporting improvement within a few weeks to several months. One user indicated a significant reduction in knee pain after one can of the supplement, stating that their knee pain improved tremendously Read Review. Another reviewer mentioned that after just six months, their bone condition improved enough to receive a dental implant, showcasing the potential for longer-term benefits Read Review.
It's also worth noting that many users emphasize the importance of consistent use to achieve maximum benefits, as evidenced by a user who experienced improvements in joint and bone pain after spending some time on the supplement Read Review. Overall, while some may notice immediate relief in a matter of weeks, others might find the most significant effects requiring several months of consistent supplementation.
Scientific research supports the use of vitamin D as a beneficial supplement for alleviating bone pain, particularly in specific populations. For instance, a study on postmenopausal women recovering from vertebral fractures indicated that adequate vitamin D levels can significantly reduce the risk of new fractures and associated bone pain. Participants with low serum levels of 25-hydroxyvitamin D experienced higher incidences of refractures, emphasizing the importance of vitamin D supplementation for bone health and pain management [2]. Similarly, research focused on knee surgery patients demonstrated that those who corrected their vitamin D3 deficiency prior to surgery reported substantially better control over post-operative bone pain, showcasing vitamin D's role as a modifiable risk factor for recovery [3].
Additionally, studies involving postmenopausal women with osteoporosis have found that combining calcitriol (a form of vitamin D) with bisphosphonates not only alleviated bone pain but also improved bone density and overall quality of life [4]. Although the direct effects of other treatments like calcium on bone pain in osteomalacia have been observed, isolating its impact remains challenging due to the complexity of treatment combinations [5]. Overall, these findings suggest that vitamin D supplementation can be a valuable addition to therapies aimed at managing bone pain.
Users have reported a range of positive improvements in their symptoms after using this calcium supplement. Many have noted significant reductions in bone pain, particularly in the knees. For instance, one user shared that their knee pain, which previously disrupted their sleep, improved tremendously after just one can of the supplement, complemented by other natural remedies Read Review. Another review highlights how the supplement has relieved the pain experienced by a mother after chemotherapy, illustrating its potential to assist with post-treatment conditions Read Review.
Consistent use of the supplement has also led to notable benefits, such as increased bone density and overall improvement in bone health. One user reported significant bone growth as noticed by their dentist after six months of use, which ultimately made them eligible for a dental implant Read Review. Additionally, multiple users emphasized the importance of the supplement in bolstering their bone health for conditions like osteoporosis, often citing improved mobility and less discomfort Read Review. Overall, while individual experiences vary, many users have found this supplement beneficial in alleviating pain and supporting bone health.
Users report positive experiences when combining this calcium supplement with other natural remedies to manage bone pain. For example, one user highlighted that along with calcium, they incorporated turmeric, boswellia, and collagen, which significantly improved their knee pain after using the supplement for just one can Read Review. Another reviewer mentioned how the supplement has not only helped their mother after chemotherapy but also provided relief to their sister for her arm pain, illustrating the supplement's versatility in addressing various bone pain issues within a family setting Read Review.
Moreover, several users noted the importance of combining this calcium supplement with vitamin D for better absorption and effectiveness. One reviewer emphasized that Citracal, enriched with high levels of Vitamin D3, helped them combat bone pain effectively, suggesting that adequate calcium and Vitamin D play crucial roles in supporting bone health and reducing osteoporosis risk Read Review. Overall, the consensus appears to favor combining this calcium supplement with complementary supplements for enhanced results in managing bone pain.
Users report that the right dosage of Calcium Plus Vitamin D can lead to significant improvements in bone pain management. Many testimonials highlight the efficacy of the supplement in alleviating bone pain, particularly for individuals suffering from conditions like osteoporosis. For instance, one user notes that their mother saw a disappearance of bone pain after chemotherapy following the introduction of a calcium supplement into her routine Read Review. Another reviewer mentions that taking the supplement helped relieve intense knee pain that disrupted their sleep, underscoring the supplement's role in effectively managing joint and bone discomfort Read Review.
In terms of specific dosages, several users emphasize the importance of combining calcium with vitamin D for optimal results. One user reports taking two tablets daily to ensure sufficient calcium intake, particularly as they approach their 60s Read Review. Another review highlights a formulation with a recommended amount of 1200 mg calcium and 1000 IU of vitamin D3, which users found effective for better absorption and pain relief Read Review. Overall, a balance of calcium and vitamin D is consistently mentioned as essential for treating bone pain and improving bone health.
9
Significant pain relief
This supplement truly works for my bone pain. My knee used to hurt significantly, even waking me at night. I added calcium along with turmeric, boswellia, and collagen. It's a sustained-release formula, which I prefer. After one can, my knee pain improved tremendously; calcium is surely beneficial.
10
Increased bone growth
1 people found this helpful
This calcium truly works! Both my husband and I take it, and our dentist has noticed significant bone growth. After just six months, my bone condition improved enough for me to receive a dental implant. Very satisfied with this calcium.
7.5
Eases joint pain
I’ve noticed that when I use this supplement, my joint and bone pain in my back are alleviated.
9
Eliminated bone pain
2 people found this helpful
This calcium has significantly helped my mother after chemotherapy. Her osteoporosis worsened, causing bone pain, but after she started taking calcium, the pains disappeared. It also helped my sister with her own arm pain, and she can now raise her arms effortlessly.
7.5
Improves joint condition
This supplement has been useful for me, and I’ve purchased it numerous times. After taking it, I observed improvements in my knee joints and a reduction in bone pain.
7.5
Reduced osteoporosis risk
Citracal with high Vitamin D3 helps combat bone pain. Adequate calcium and vitamin D intake can lower the risk of osteoporosis. The Slo-Cal technology offers efficient calcium absorption, giving me 1200 mg of calcium and 1000 IU of vitamin D3 in one daily dose. Great quality for the price!
6
Sufficient calcium intake
I take two of these daily to ensure my bones receive sufficient calcium. At 60 years old, I struggle to get enough calcium in my diet.
8
Vitamin D reduces fracture risk
Association Between 25-hydroxyvitamin D Status and New Vertebral Fractures Post Percutaneous Vertebral Augmentation in Patients During Postmenopause: A Retrospective Case-control Study.
We investigated the connection between vitamin D levels and the risk of new vertebral fractures in postmenopausal women who had undergone percutaneous vertebral augmentation. Through a retrospective case-control study involving patients aged 50 and older, we analyzed records to categorize participants into groups based on whether they experienced refractures and how serum levels of 25-hydroxyvitamin D (25[OH]D) influenced these outcomes.
Our findings revealed that low levels of serum 25(OH)D are linked to an increased risk of new vertebral fractures in these patients. What's noteworthy is that vitamin D plays a crucial role in maintaining bone health, and adequate levels can help reduce the likelihood of subsequent fractures after surgery. This underscores the potential importance of vitamin D supplementation for patients recovering from vertebral augmentation.
In conclusion, ensuring that patients receive appropriate vitamin D intake might be pivotal in preventing further bone pain and fractures following surgery. By addressing vitamin D deficiency, we could significantly improve bone health outcomes and enhance the quality of life for postmenopausal women recovering from vertebral fractures.
9
Vitamin D3 correction improves pain
Role of Pre-operative Correction of Vitamin D3 Deficiency in Controlling Post-operative Bone Pain after Unicompartmental Knee Arthroplasty.
We explored the impact of vitamin D3 levels on bone pain that patients experience after undergoing unicompartmental knee arthroplasty (UKA). The study involved 240 participants who were divided into three groups based on their vitamin D status—some received treatment before surgery, some after, and others had normal levels to begin with.
By administering vitamin D3 in three doses, we aimed to see if correcting deficiencies could alleviate post-operative bone pain. Throughout the recovery period, we measured pain levels using the visual analog scale at various intervals after the surgery.
Our findings clearly demonstrated that patients who corrected their vitamin D3 deficiency before surgery reported significantly better pain control after the operation compared to those who were treated afterwards or those who started with adequate levels. This highlights the importance of testing and addressing vitamin D status prior to orthopedic procedures, showing that it is a modifiable risk factor affecting recovery.
9
Effectiveness of calcitriol combination therapy
Clinical efficacy and outcomes of calcitriol combined with bisphosphonates in the treatment of postmenopausal osteoporosis: A quasi-experimental study.
We conducted an insightful study to analyze how combining calcitriol, a form of vitamin D, with bisphosphonates affects bone pain in postmenopausal women suffering from osteoporosis. This quasi-experimental approach allowed us to compare two groups: one treated with calcitriol alone and the other with the combination treatment.
Our findings highlighted that adding bisphosphonates to calcitriol significantly alleviated bone pain among the participants. We observed improved evaluations of joint pain through the Visual Analogue Scale/Score, indicating that patients felt much better post-treatment. Furthermore, the combination therapy enhanced the patients' overall daily living capabilities and positively influenced bone metabolism and density.
Overall, our results suggest that calcitriol combined with bisphosphonates is effective in not just relieving pain but also supporting the long-term health of bones in postmenopausal women. This approach may pave the way for improved treatment strategies for osteoporosis in this demographic.
8
Calcium's role in bone pain unclear
In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution.
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
References
Saki F, Karamizadeh Z, Nasirabadi S, Mumm S, McAlister WH, et al. Juvenile paget's disease in an Iranian kindred with vitamin D deficiency and novel homozygous TNFRSF11B mutation. J Bone Miner Res. 2013;28:1501. 10.1002/jbmr.1868
Zhang SB, Yang J, Xu HW, Yi YY, Ren CX, et al. Association Between 25-hydroxyvitamin D Status and New Vertebral Fractures Post Percutaneous Vertebral Augmentation in Patients During Postmenopause: A Retrospective Case-control Study. Pain Physician. 2025;28:E31.
Rajani AM, Mittal A, Kulkarni VU, Rajani KA, Rajani KA. Role of Pre-operative Correction of Vitamin D3 Deficiency in Controlling Post-operative Bone Pain after Unicompartmental Knee Arthroplasty. Malays Orthop J. 2024;18:7. 10.5704/MOJ.2411.002
Han K, Wang X. Clinical efficacy and outcomes of calcitriol combined with bisphosphonates in the treatment of postmenopausal osteoporosis: A quasi-experimental study. Medicine (Baltimore). 2024;103:e40171. 10.1097/MD.0000000000040171
von Brackel FN, Grambeck J, Barvencik F, Amling M, Oheim R. In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution. JBMR Plus. 2024;8:ziae139. 10.1093/jbmrpl/ziae139