Last update
4/8/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
USERS' SCORE
Good
Based on 6 Reviews
8.4
Top Medical Research Studies
9
We analyzed various medical treatments for solitary rectal ulcer syndrome (SRUS), focusing on fiber-rich diets among other options. After reviewing trials and studies, we observed that patients treated with a high-fiber diet, along with other medical interventions, generally reported improvements and achieved ulcer remission.
While most treatments were effective, we didn’t find the fiber treatment to be a standout option compared to others. Nevertheless, the overall findings highlight the importance of medical intervention for managing SRUS effectively.
While most treatments were effective, we didn’t find the fiber treatment to be a standout option compared to others. Nevertheless, the overall findings highlight the importance of medical intervention for managing SRUS effectively.
Read More
8
We assessed how including silage in the diets of fattening pigs impacts their health, specifically looking at gastric ulcers and skin lesions. In our study, 128 pigs were divided into groups and fed either traditional feed or mixed diets containing silage.
While we didn’t find significant improvements in skin lesions, we observed that pigs receiving silage had noticeably fewer gastric lesions and ulcers compared to those on standard diets. This suggests that adding silage can be beneficial for gut health in pigs.
While we didn’t find significant improvements in skin lesions, we observed that pigs receiving silage had noticeably fewer gastric lesions and ulcers compared to those on standard diets. This suggests that adding silage can be beneficial for gut health in pigs.
Read More
9
TTT boosts ulcer healing efficiency
We explored how tibial transverse transport (TTT) can speed up healing in chronic foot ulcers through its effects on certain cells and pathways. In our study, we observed rabbits with induced foot ulcers undergoing unilateral and bilateral TTT surgeries.
Results showed that TTT not only decreased healing time but also increased critical healing factors like collagen and microvascular markers. The treatment amplified the levels of VEGFA and CXCL12, which help mobilize endothelial progenitor cells, thereby enhancing blood vessel formation and aiding in the overall healing process.
These findings suggest that TTT is an effective method for accelerating ulcer recovery.
Results showed that TTT not only decreased healing time but also increased critical healing factors like collagen and microvascular markers. The treatment amplified the levels of VEGFA and CXCL12, which help mobilize endothelial progenitor cells, thereby enhancing blood vessel formation and aiding in the overall healing process.
These findings suggest that TTT is an effective method for accelerating ulcer recovery.
Read More
Most Useful Reviews
9
Effective zinc supplement
263 people found this helpful
Highly dosed and well-absorbed zinc. It plays a crucial role in immune function and can prevent ulcer healing issues. My father used it to heal a leg ulcer, which had not improved with prescribed therapies. It healed quickly, and my husband took it to enhance his vision and noticed an increase in testosterone levels too.
Read More
9
No more ulcers
9 people found this helpful
Mouth ulcers have completely healed. Regardless of how many hours I sleep, I feel energised and no longer suffer from ulcers. After taking this supplement, I wake up earlier and feel fantastic. If you tire easily, I highly recommend trying it!
Read More
0
No improvement noted
8 people found this helpful
Complete nonsense! I awaited these pills as if they were manna from the sky. After finishing the jar, my hair began to fall out, my fingernails weakened, and I developed ulcers on my mucous membrane. There were no improvements at all! Instead, it felt as if everything had gotten worse. Normally, I don’t get ill, but here I was, experiencing one issue after the other. I was influenced by the reviews and the price, but my immunity has weakened, and I regret the months wasted on this.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
- All Researches
9
TTT boosts ulcer healing efficiency
We explored how tibial transverse transport (TTT) can speed up healing in chronic foot ulcers through its effects on certain cells and pathways. In our study, we observed rabbits with induced foot ulcers undergoing unilateral and bilateral TTT surgeries.
Results showed that TTT not only decreased healing time but also increased critical healing factors like collagen and microvascular markers. The treatment amplified the levels of VEGFA and CXCL12, which help mobilize endothelial progenitor cells, thereby enhancing blood vessel formation and aiding in the overall healing process.
These findings suggest that TTT is an effective method for accelerating ulcer recovery.
Results showed that TTT not only decreased healing time but also increased critical healing factors like collagen and microvascular markers. The treatment amplified the levels of VEGFA and CXCL12, which help mobilize endothelial progenitor cells, thereby enhancing blood vessel formation and aiding in the overall healing process.
These findings suggest that TTT is an effective method for accelerating ulcer recovery.
Read More
9
We analyzed various medical treatments for solitary rectal ulcer syndrome (SRUS), focusing on fiber-rich diets among other options. After reviewing trials and studies, we observed that patients treated with a high-fiber diet, along with other medical interventions, generally reported improvements and achieved ulcer remission.
While most treatments were effective, we didn’t find the fiber treatment to be a standout option compared to others. Nevertheless, the overall findings highlight the importance of medical intervention for managing SRUS effectively.
While most treatments were effective, we didn’t find the fiber treatment to be a standout option compared to others. Nevertheless, the overall findings highlight the importance of medical intervention for managing SRUS effectively.
Read More
9
Silver-hyaluronan dressing aids healing
We examined a new type of wound dressing made from silver and hyaluronan that shows promise for treating chronic ulcers. By combining these components, we created fabrics with strong antibacterial properties against bacteria like E. coli and found no harmful effects on human skin cells.
In tests with rats, those treated with our fabric healed faster compared to traditional options. Ultimately, our research indicates that this advanced dressing could enhance recovery for various wounds, offering hopeful applications in medical treatment and tissue engineering.
In tests with rats, those treated with our fabric healed faster compared to traditional options. Ultimately, our research indicates that this advanced dressing could enhance recovery for various wounds, offering hopeful applications in medical treatment and tissue engineering.
Read More
8
We assessed how including silage in the diets of fattening pigs impacts their health, specifically looking at gastric ulcers and skin lesions. In our study, 128 pigs were divided into groups and fed either traditional feed or mixed diets containing silage.
While we didn’t find significant improvements in skin lesions, we observed that pigs receiving silage had noticeably fewer gastric lesions and ulcers compared to those on standard diets. This suggests that adding silage can be beneficial for gut health in pigs.
While we didn’t find significant improvements in skin lesions, we observed that pigs receiving silage had noticeably fewer gastric lesions and ulcers compared to those on standard diets. This suggests that adding silage can be beneficial for gut health in pigs.
Read More
8
We investigated how dietary fiber impacts the formation of small intestinal ulcers caused by non-steroidal anti-inflammatory drugs (NSAIDs) in dogs. By varying the fiber content in their diets and examining the resulting gastrointestinal lesions after treatment with NSAIDs, we noticed some interesting patterns.
Dogs on a very low fiber diet showed no lesions, while those on a regular diet had many. Interestingly, moving to low-fiber options led to reduced lesions, suggesting that lower fiber intake may help decrease gastrointestinal side effects from NSAIDs.
Dogs on a very low fiber diet showed no lesions, while those on a regular diet had many. Interestingly, moving to low-fiber options led to reduced lesions, suggesting that lower fiber intake may help decrease gastrointestinal side effects from NSAIDs.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective zinc supplement
263 people found this helpful
Highly dosed and well-absorbed zinc. It plays a crucial role in immune function and can prevent ulcer healing issues. My father used it to heal a leg ulcer, which had not improved with prescribed therapies. It healed quickly, and my husband took it to enhance his vision and noticed an increase in testosterone levels too.
Read More
9
No more ulcers
9 people found this helpful
Mouth ulcers have completely healed. Regardless of how many hours I sleep, I feel energised and no longer suffer from ulcers. After taking this supplement, I wake up earlier and feel fantastic. If you tire easily, I highly recommend trying it!
Read More
0
No improvement noted
8 people found this helpful
Complete nonsense! I awaited these pills as if they were manna from the sky. After finishing the jar, my hair began to fall out, my fingernails weakened, and I developed ulcers on my mucous membrane. There were no improvements at all! Instead, it felt as if everything had gotten worse. Normally, I don’t get ill, but here I was, experiencing one issue after the other. I was influenced by the reviews and the price, but my immunity has weakened, and I regret the months wasted on this.
Read More
8
Fast healing noted
4 people found this helpful
I take one tablet in the morning and one in the evening. My urine is yellow all day, indicating release. I've not noticed other effects, but my mouth ulcer healed quickly. While it makes my negative state zero, I wonder if I could create a positive from that.
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7
Effective sustained relief
2 people found this helpful
I opted for this product due to its sustained release. Even taking it in the evening, my urine the following day retains the Vitamin B colour, indicating its effectiveness. I believe that without this, I would likely develop mouth ulcers.
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Frequently Asked Questions
9
No more ulcers
9 people found this helpful
Mouth ulcers have completely healed. Regardless of how many hours I sleep, I feel energised and no longer suffer from ulcers. After taking this supplement, I wake up earlier and feel fantastic. If you tire easily, I highly recommend trying it!
References
- Tian W, Feng B, Zhang L, Dai G, Lin L, et al. Tibial transverse transport induces mobilization of endothelial progenitor cells to accelerate angiogenesis and ulcer wound healing through the VEGFA/CXCL12 pathway. Biochem Biophys Res Commun. 2024;709:149853. 10.1016/j.bbrc.2024.149853
- Varol Fİ, Güngör Ş, Selimoğlu MA, Şamdancı E. Rare Cause of Hematochezia in Children: Solitary Rectal Ulcer, Single Center Experience. Korean J Gastroenterol. 2024;83:17. 10.4166/kjg.2023.093
- Friman J, Verbeek E, Sannö A, Åkerfeldt MP. Inclusion of silage in diets to fattening pigs: effect on gastric ulcers and skin lesions. Animal. 2024;18:101045. 10.1016/j.animal.2023.101045
- Qari Y, Mosli M. A systematic review and meta-analysis of the efficacy of medical treatments for the management of solitary rectal ulcer syndrome. Saudi J Gastroenterol. 2020;26:4. 10.4103/sjg.SJG_213_19
- Gouriou C, Chambaz M, Ropert A, Bouguen G, Desfourneaux V, et al. A systematic literature review on solitary rectal ulcer syndrome: is there a therapeutic consensus in 2018?. Int J Colorectal Dis. 2018;33:1647. 10.1007/s00384-018-3162-z
- Abdel-Mohsen AM, Jancar J, Abdel-Rahman RM, Vojtek L, Hyršl P, et al. A novel in situ silver/hyaluronan bio-nanocomposite fabrics for wound and chronic ulcer dressing: In vitro and in vivo evaluations. Int J Pharm. 2017;520:241. 10.1016/j.ijpharm.2017.02.003
- AlGhulayqah AI, Abu-Farhaneh EH, AlSohaibani FI, Almadi MA, AlMana HM. Solitary rectal ulcer syndrome: A single-center case series. Saudi J Gastroenterol. 2016;22:456. 10.4103/1319-3767.195555
- Satoh H, Kondo R, Shinoda T, Idaka S, Ishigami K, et al. Diets with no or low amounts of dietary fiber can reduce small intestinal ulcers induced by non-steroidal anti-inflammatory drugs in dogs. J Physiol Pharmacol. 2016;67:563. PubMed
- Satoh H, Matsumoto H, Hirakawa T, Wada N. Soluble Dietary Fibers Can Protect the Small Intestinal Mucosa Without Affecting the Anti-inflammatory Effect of Indomethacin in Adjuvant-Induced Arthritis Rats. Dig Dis Sci. 2016;61:91. 10.1007/s10620-015-3889-0
- Temiz A, Tander B, Temiz M, Barış S, Arıtürk E. A rare cause of chronic rectal bleeding in children; solitary rectal ulcer: case report. Ulus Travma Acil Cerrahi Derg. 2011;17:173. PubMed
- Suresh N, Ganesh R, Sathiyasekaran M. Solitary rectal ulcer syndrome: a case series. Indian Pediatr. 2010;47:1059. PubMed
- Somani SK, Ghosh A, Avasthi G, Goyal R, Gupta P. Healing of solitary rectal ulcers with multiple sessions of argon plasma coagulation. Dig Endosc. 2010;22:107. 10.1111/j.1443-1661.2010.00941.x
- Somani SK, Ghosh A, Avasthi G, Goyal R, Gupta P. Healing of a bleeding solitary rectal ulcer with multiple sessions of argon plasma. Gastrointest Endosc. 2010;71:578. 10.1016/j.gie.2009.10.038
- Satoh H. Role of dietary fiber in formation and prevention of small intestinal ulcers induced by nonsteroidal anti-inflammatory drug. Curr Pharm Des. 2010;16:1209. PubMed
- Satoh H, Shiotani S, Otsuka N, Hatao K, Nishimura S. Role of dietary fibres, intestinal hypermotility and leukotrienes in the pathogenesis of NSAID-induced small intestinal ulcers in cats. Gut. 2009;58:1590. 10.1136/gut.2008.156596
- Ortega AE, Klipfel N, Kelso R, Petrone P, Román I, et al. Changing concepts in the pathogenesis, evaluation, and management of solitary rectal ulcer syndrome. Am Surg. 2008;74:967. PubMed
