Supplement Facts
Serving Size: 1 lozenge
Amount Per Serving
%DV
Vitamin C (as ascorbic acid)
50 mg
56%
Folate
667 mcg DFE (400 mcg folic acid)
167%
Vitamin B12 (as methylcobalamin)
3,000 mcg
125,000%
The product is found useful for the following medical conditions
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Questionable
Based on 11 Researches
6.3
USERS' SCORE
Good
Based on 2 Reviews
8.5
0
Vitamin B12 ineffective for CFS
We explored the effectiveness of high-dose vitamin B12 injections on chronic fatigue syndrome (CFS) through two case reports that utilized N of 1 trials. This approach allowed us to make tailored treatment decisions based on individual responses to the therapy.
In one case, we found that high-dose vitamin B12 injections did not yield positive results, leaving the patient without significant relief from their symptoms. Conversely, in another case, we observed that nimodipine proved to be a very effective treatment for that patient’s chronic fatigue.
These findings suggest that while vitamin B12 may not be helpful for everyone suffering from CFS, other treatments like nimodipine can be beneficial. Thus, personalized treatment strategies are key in managing this complex and varied condition.
In one case, we found that high-dose vitamin B12 injections did not yield positive results, leaving the patient without significant relief from their symptoms. Conversely, in another case, we observed that nimodipine proved to be a very effective treatment for that patient’s chronic fatigue.
These findings suggest that while vitamin B12 may not be helpful for everyone suffering from CFS, other treatments like nimodipine can be beneficial. Thus, personalized treatment strategies are key in managing this complex and varied condition.
9
Effective energy boost
Most Useful Review
4 people found this helpful
Great Energy Booster I have fibromyalgia and suffer from severe chronic fatigue syndrome. I have taken the equivalent mcg from other manufacturers, but this is the one that truly provides me with an energy boost. I never want to run out of it!
Updated: Apr 2025
Anemia details
SCIENTIFIC SCORE
Possibly Effective
Based on 33 Researches
7.8
USERS' SCORE
Good
Based on 3 Reviews
8.4
9.5
We explored the case of a 23-month-old boy suffering from severe pancytopenia linked to Imerslund-Gräsbeck syndrome, a rare condition caused by an inability to absorb vitamin B12. Upon diagnosis, the boy received vitamin B12 replacement therapy, which effectively addressed his symptoms and improved his health.
This case highlights the significance of early detection and treatment of IGS to avoid potential neurological damage. It's crucial to recognize this condition, even when neurological symptoms are absent, to provide timely care.
This case highlights the significance of early detection and treatment of IGS to avoid potential neurological damage. It's crucial to recognize this condition, even when neurological symptoms are absent, to provide timely care.
8
Increased B12 levels
Most Useful Review
2 people found this helpful
Helped to raise my B12 levels! I take one tablet daily, and my B12 has improved significantly. This method is convenient as it can be taken sublingually after meals. When using traditional pills that need to be swallowed, absorption of B12 is less effective. Therefore, I prefer this method. The therapeutic dosage works well for increasing B12, but prolonged use isn't advisable as excess B12 can be harmful. It’s beneficial for issues related to anemia, hair, skin, and memory. Thank you for the support, wishing everyone good health!
Updated: Apr 2026
Autoimmune Disorder details
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.2
9
We examined a case of a 51-year-old Ugandan man who experienced recurring lower limb weakness linked to pernicious anemia, an autoimmune condition causing vitamin B12 deficiency. After initial treatments, his symptoms reappeared, leading to further testing that confirmed the diagnosis.
Treatment with vitamin B12 injections significantly improved his condition. This case emphasizes the need for healthcare providers to recognize the signs of vitamin B12 deficiency early, particularly in resource-limited settings, to ensure timely diagnosis and treatment.
Treatment with vitamin B12 injections significantly improved his condition. This case emphasizes the need for healthcare providers to recognize the signs of vitamin B12 deficiency early, particularly in resource-limited settings, to ensure timely diagnosis and treatment.
7.5
Effective treatment
Most Useful Review
Wonderful! The product was well arranged and perfectly packed. The effect is certainly noticeable! I will order more! The delivery was also very quick.
Updated: Apr 2025
Sleep Apnea details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 3 Reviews
8.2
8
Folate may protect against OSA
We conducted a thorough investigation into how dietary components, particularly folate, relate to the severity of obstructive sleep apnea (OSA) in a group of adults living in Cyprus. Our study included a diverse sample of 303 participants aged over 18, who completed detailed food frequency and physical activity questionnaires, along with undergoing sleep studies to assess OSA severity.
In our analysis, we found that patients with more severe OSA, identified by a higher apnea-hypopnea index (AHI), had significant characteristics such as increased body mass index (BMI) and higher caloric intake. Interestingly, those with moderate to severe OSA reported higher folic acid consumption compared to those with milder forms of the condition.
This suggests that while greater energy intake appears to correlate with more severe OSA, a higher intake of folate may offer some protective benefits. However, it’s essential to note that we did not isolate the effects of folate alone, as other dietary factors were also at play in our findings, making further research necessary to draw stronger conclusions.
Overall, our results point towards the complexity of dietary influences on sleep apnea severity, highlighting folate as a potentially beneficial nutrient alongside other lifestyle factors.
In our analysis, we found that patients with more severe OSA, identified by a higher apnea-hypopnea index (AHI), had significant characteristics such as increased body mass index (BMI) and higher caloric intake. Interestingly, those with moderate to severe OSA reported higher folic acid consumption compared to those with milder forms of the condition.
This suggests that while greater energy intake appears to correlate with more severe OSA, a higher intake of folate may offer some protective benefits. However, it’s essential to note that we did not isolate the effects of folate alone, as other dietary factors were also at play in our findings, making further research necessary to draw stronger conclusions.
Overall, our results point towards the complexity of dietary influences on sleep apnea severity, highlighting folate as a potentially beneficial nutrient alongside other lifestyle factors.
9
Significant sleep improvement
Most Useful Review
1 people found this helpful
I couldn't live without it! My sleep has greatly improved since I started using this product! It has also alleviated my back problems.
Updated: Apr 2025
Knee Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 2 Reviews
8.1
7
We explored the relationship between folate intake and knee pain in patients suffering from knee osteoarthritis (OA) over a two-year period. In this insightful study, data was collected from participants enrolled in a rigorous clinical trial designed to assess the effects of vitamin D supplementation. While the original trial focused on vitamin D, our post-hoc analysis allowed us to dive into the potential benefits of folate on knee pain and related conditions.
Through the use of dietary questionnaires, we assessed the average daily folate consumption of participants. In addition to evaluating knee pain levels at various intervals, other factors such as inflammatory markers, muscle strength, and comorbidities were also monitored. Impressively, we found that increased folate intake was associated with reduced knee pain and lower levels of inflammatory substances known as adipokines.
Furthermore, individuals with higher folate consumption reported fewer comorbid conditions, suggesting that folate may indeed play a role in enhancing overall health for those dealing with knee OA. However, while our findings are promising, they highlight the need for further research to fully understand the extent of folate's impact in this context.
Through the use of dietary questionnaires, we assessed the average daily folate consumption of participants. In addition to evaluating knee pain levels at various intervals, other factors such as inflammatory markers, muscle strength, and comorbidities were also monitored. Impressively, we found that increased folate intake was associated with reduced knee pain and lower levels of inflammatory substances known as adipokines.
Furthermore, individuals with higher folate consumption reported fewer comorbid conditions, suggesting that folate may indeed play a role in enhancing overall health for those dealing with knee OA. However, while our findings are promising, they highlight the need for further research to fully understand the extent of folate's impact in this context.
7.5
Improved workouts
Most Useful Review
5 people found this helpful
I improved my workouts significantly after discovering I was deficient in B-12 through muscle testing. I switched from a B complex supplement to methyl B-12, which my trainer recommended. Since then, my training sessions have enhanced; I've become stronger and increased my endurance. I also appear to burn more fat, possibly due to the enhanced muscle from the improved workouts. Furthermore, I experience less muscle pain upon waking now.
Updated: Apr 2025
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