' 
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.5
USERS' SCORE
Good
Based on 4 Reviews
8.8
Supplement Facts
Serving Size: 1 tablet
Amount Per Serving
%DV
Selenium (as L-selenomethionine)
100 mcg
182%
Top Medical Research Studies
9
Selenium nanoparticles reduce allergies
Translational Selenium Nanoparticles to Attenuate Allergic Dermatitis through Nrf2-Keap1-Driven Activation of Selenoproteins.
Direct exploration of selenium's effects
We examined how selenium, a trace element known for its role in health, can help those suffering from allergic dermatitis. In our exploration, we focused on how selenium nanoparticles, specifically designed for easier manufacturing and use, can activate the body's natural defenses against allergies.
The study highlighted how selenium impacts allergic reactions by enhancing the production of selenoproteins, which are crucial in regulating inflammation and oxidative stress. We saw that these selenium nanoparticles effectively inhibited mast cell activation. Mast cells are known to release substances that can trigger allergic reactions, so by reducing their activation, the potential for severe allergic responses decreased.
Additionally, through a series of experiments on allergic mouse models, we confirmed the nanoparticles increased selenium levels in the skin, which led to a reduction in inflammatory cells and mast cell activation. The results indicated significant therapeutic benefits, providing a promising avenue for managing allergic reactions.
Ultimately, this study not only demonstrates the innovative use of selenium nanoparticles in treating allergies but also emphasizes the importance of scaling up their production for broader clinical application.
The study highlighted how selenium impacts allergic reactions by enhancing the production of selenoproteins, which are crucial in regulating inflammation and oxidative stress. We saw that these selenium nanoparticles effectively inhibited mast cell activation. Mast cells are known to release substances that can trigger allergic reactions, so by reducing their activation, the potential for severe allergic responses decreased.
Additionally, through a series of experiments on allergic mouse models, we confirmed the nanoparticles increased selenium levels in the skin, which led to a reduction in inflammatory cells and mast cell activation. The results indicated significant therapeutic benefits, providing a promising avenue for managing allergic reactions.
Ultimately, this study not only demonstrates the innovative use of selenium nanoparticles in treating allergies but also emphasizes the importance of scaling up their production for broader clinical application.
Read More
9
Selenium polysaccharides reduce allergies
Se-rich tea polysaccharide extracted by high hydrostatic pressure attenuated anaphylaxis by improving gut microbiota and metabolic regulation.
Study highlights selenium’s allergy potential
We explored the role of selenium-rich tea polysaccharides (Se-TPS) in managing allergies, focusing on how they influence immune responses and gut health. Using a method called high hydrostatic pressure, we extracted Se-TPS at a pressure of 400 MPa for a specific duration. This process allowed us to isolate several polysaccharide components, particularly Se-TPS3-4, which turned out to be the most effective.
Our research involved both laboratory experiments and tests on mice sensitized to a specific allergen. We observed that these polysaccharides reduced the release of various inflammatory substances, including histamine and interleukin-4, both of which are known to play roles in allergic reactions. In the treated mice, levels of undesirable immune markers decreased, while those associated with a balanced immune response increased.
Importantly, we found that Se-TPS also encouraged the growth of beneficial gut bacteria, such as Lactobacillus, while enhancing metabolites that can support overall gut health. These findings indicate the strong potential of selenium-rich tea polysaccharides as a natural way to reduce allergic reactions by improving immune balance and gut microbiota.
Our research involved both laboratory experiments and tests on mice sensitized to a specific allergen. We observed that these polysaccharides reduced the release of various inflammatory substances, including histamine and interleukin-4, both of which are known to play roles in allergic reactions. In the treated mice, levels of undesirable immune markers decreased, while those associated with a balanced immune response increased.
Importantly, we found that Se-TPS also encouraged the growth of beneficial gut bacteria, such as Lactobacillus, while enhancing metabolites that can support overall gut health. These findings indicate the strong potential of selenium-rich tea polysaccharides as a natural way to reduce allergic reactions by improving immune balance and gut microbiota.
Read More
9
Selenium influences milk allergy response
Selenium Modulates the Allergic Response to Whey Protein in a Mouse Model for Cow's Milk Allergy.
Highly relevant to selenium and allergies
We investigated the impact of dietary selenium on cow's milk allergy, a common condition affecting infants. In our study, we used a mouse model and sensitized three-week-old female C3H/HeOuJ mice with whey protein and cholera toxin. These mice were then divided into groups and fed diets with varying levels of selenium: control, low, medium, or high.
After subjecting the mice to a whey challenge, we noted some interesting changes. Notably, the body temperature of mice on a medium selenium diet was significantly higher 60 minutes post-challenge, suggesting a less severe allergic reaction. We also observed decreased levels of allergen-specific immunoglobulin E and reduced release of mouse mast cell protease-1, indicating a dampened immune response.
This research points towards selenium supplementation as a potential method to modulate allergic reactions to whey. By lowering specific antibody responses and mast cell activity, selenium might help lessen the severity of allergies associated with cow's milk. Overall, our findings could open up new avenues for managing food allergies effectively.
After subjecting the mice to a whey challenge, we noted some interesting changes. Notably, the body temperature of mice on a medium selenium diet was significantly higher 60 minutes post-challenge, suggesting a less severe allergic reaction. We also observed decreased levels of allergen-specific immunoglobulin E and reduced release of mouse mast cell protease-1, indicating a dampened immune response.
This research points towards selenium supplementation as a potential method to modulate allergic reactions to whey. By lowering specific antibody responses and mast cell activity, selenium might help lessen the severity of allergies associated with cow's milk. Overall, our findings could open up new avenues for managing food allergies effectively.
Read More
Most Useful Reviews
9.5
Effective against allergies
Great product! It is well absorbed and does not cause allergies. Thank you, iHerb!
Read More
9.5
Aids recovery
This helped with recovering from COVID-19 in conjunction with Zinc, vitamin C, and vitamin D. It did not trigger any allergies.
Read More
9.5
Highly recommended
đź‘Ť The doctor recommended this. Another brand caused an allergy, but this one is excellent.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.5
9
Selenium polysaccharides reduce allergies
Se-rich tea polysaccharide extracted by high hydrostatic pressure attenuated anaphylaxis by improving gut microbiota and metabolic regulation.
Study highlights selenium’s allergy potential
We explored the role of selenium-rich tea polysaccharides (Se-TPS) in managing allergies, focusing on how they influence immune responses and gut health. Using a method called high hydrostatic pressure, we extracted Se-TPS at a pressure of 400 MPa for a specific duration. This process allowed us to isolate several polysaccharide components, particularly Se-TPS3-4, which turned out to be the most effective.
Our research involved both laboratory experiments and tests on mice sensitized to a specific allergen. We observed that these polysaccharides reduced the release of various inflammatory substances, including histamine and interleukin-4, both of which are known to play roles in allergic reactions. In the treated mice, levels of undesirable immune markers decreased, while those associated with a balanced immune response increased.
Importantly, we found that Se-TPS also encouraged the growth of beneficial gut bacteria, such as Lactobacillus, while enhancing metabolites that can support overall gut health. These findings indicate the strong potential of selenium-rich tea polysaccharides as a natural way to reduce allergic reactions by improving immune balance and gut microbiota.
Our research involved both laboratory experiments and tests on mice sensitized to a specific allergen. We observed that these polysaccharides reduced the release of various inflammatory substances, including histamine and interleukin-4, both of which are known to play roles in allergic reactions. In the treated mice, levels of undesirable immune markers decreased, while those associated with a balanced immune response increased.
Importantly, we found that Se-TPS also encouraged the growth of beneficial gut bacteria, such as Lactobacillus, while enhancing metabolites that can support overall gut health. These findings indicate the strong potential of selenium-rich tea polysaccharides as a natural way to reduce allergic reactions by improving immune balance and gut microbiota.
Read More
9
Selenium nanoparticles reduce allergies
Translational Selenium Nanoparticles to Attenuate Allergic Dermatitis through Nrf2-Keap1-Driven Activation of Selenoproteins.
Direct exploration of selenium's effects
We examined how selenium, a trace element known for its role in health, can help those suffering from allergic dermatitis. In our exploration, we focused on how selenium nanoparticles, specifically designed for easier manufacturing and use, can activate the body's natural defenses against allergies.
The study highlighted how selenium impacts allergic reactions by enhancing the production of selenoproteins, which are crucial in regulating inflammation and oxidative stress. We saw that these selenium nanoparticles effectively inhibited mast cell activation. Mast cells are known to release substances that can trigger allergic reactions, so by reducing their activation, the potential for severe allergic responses decreased.
Additionally, through a series of experiments on allergic mouse models, we confirmed the nanoparticles increased selenium levels in the skin, which led to a reduction in inflammatory cells and mast cell activation. The results indicated significant therapeutic benefits, providing a promising avenue for managing allergic reactions.
Ultimately, this study not only demonstrates the innovative use of selenium nanoparticles in treating allergies but also emphasizes the importance of scaling up their production for broader clinical application.
The study highlighted how selenium impacts allergic reactions by enhancing the production of selenoproteins, which are crucial in regulating inflammation and oxidative stress. We saw that these selenium nanoparticles effectively inhibited mast cell activation. Mast cells are known to release substances that can trigger allergic reactions, so by reducing their activation, the potential for severe allergic responses decreased.
Additionally, through a series of experiments on allergic mouse models, we confirmed the nanoparticles increased selenium levels in the skin, which led to a reduction in inflammatory cells and mast cell activation. The results indicated significant therapeutic benefits, providing a promising avenue for managing allergic reactions.
Ultimately, this study not only demonstrates the innovative use of selenium nanoparticles in treating allergies but also emphasizes the importance of scaling up their production for broader clinical application.
Read More
9
Selenium influences milk allergy response
Selenium Modulates the Allergic Response to Whey Protein in a Mouse Model for Cow's Milk Allergy.
Highly relevant to selenium and allergies
We investigated the impact of dietary selenium on cow's milk allergy, a common condition affecting infants. In our study, we used a mouse model and sensitized three-week-old female C3H/HeOuJ mice with whey protein and cholera toxin. These mice were then divided into groups and fed diets with varying levels of selenium: control, low, medium, or high.
After subjecting the mice to a whey challenge, we noted some interesting changes. Notably, the body temperature of mice on a medium selenium diet was significantly higher 60 minutes post-challenge, suggesting a less severe allergic reaction. We also observed decreased levels of allergen-specific immunoglobulin E and reduced release of mouse mast cell protease-1, indicating a dampened immune response.
This research points towards selenium supplementation as a potential method to modulate allergic reactions to whey. By lowering specific antibody responses and mast cell activity, selenium might help lessen the severity of allergies associated with cow's milk. Overall, our findings could open up new avenues for managing food allergies effectively.
After subjecting the mice to a whey challenge, we noted some interesting changes. Notably, the body temperature of mice on a medium selenium diet was significantly higher 60 minutes post-challenge, suggesting a less severe allergic reaction. We also observed decreased levels of allergen-specific immunoglobulin E and reduced release of mouse mast cell protease-1, indicating a dampened immune response.
This research points towards selenium supplementation as a potential method to modulate allergic reactions to whey. By lowering specific antibody responses and mast cell activity, selenium might help lessen the severity of allergies associated with cow's milk. Overall, our findings could open up new avenues for managing food allergies effectively.
Read More
9
Selenium compound reduces allergy symptoms
Suppressive effect of 1,4-anhydro-4-seleno-D-talitol (SeTal) on atopic dermatitis-like skin lesions in mice through regulation of inflammatory mediators.
Direct relevance to allergy treatment
We explored how a novel water-soluble selenium compound, known as SeTal, impacts atopic dermatitis (AD), a common allergic skin condition. In experiments, we applied 2,4-dinitrochlorobenzene (DNCB) to sensitized mice, creating a model for AD symptoms. By treating these mice with either SeTal or hydrocortisone, we aimed to measure the severity of skin lesions and related inflammation.
The results were compelling. SeTal, at concentrations of 1% and 2%, showed significant effectiveness in reducing the symptoms and inflammatory indicators of AD. In fact, the results were comparable to, and in some cases, even better than the results achieved with hydrocortisone, a traditional steroid treatment often used for such conditions.
This study suggests that SeTal could offer a promising alternative for treating atopic dermatitis, providing a new avenue for those seeking relief from this chronic and often bothersome allergy-related skin issue. With common steroid treatments posing potential side effects, our findings around SeTal support exploring safer, more effective options in the future.
The results were compelling. SeTal, at concentrations of 1% and 2%, showed significant effectiveness in reducing the symptoms and inflammatory indicators of AD. In fact, the results were comparable to, and in some cases, even better than the results achieved with hydrocortisone, a traditional steroid treatment often used for such conditions.
This study suggests that SeTal could offer a promising alternative for treating atopic dermatitis, providing a new avenue for those seeking relief from this chronic and often bothersome allergy-related skin issue. With common steroid treatments posing potential side effects, our findings around SeTal support exploring safer, more effective options in the future.
Read More
8
Prenatal selenium reduces allergy risk
Prenatal exposure to selenium, mercury, and manganese during pregnancy and allergic diseases in early childhood: The Japan Environment and Children's study.
Highlights selenium's positive effects
We delved into the connections between prenatal exposure to certain metals—specifically, selenium, mercury, and manganese—and the risk of allergic diseases during early childhood. Using data from 94,794 mother-infant pairs from the Japan Environment and Children's study, we analyzed maternal blood samples taken during mid-pregnancy to assess levels of these metallic elements.
Our findings point to a promising role for selenium: it appears to be linked with a reduced risk of atopic dermatitis, food allergies, allergic rhinitis, and overall allergic diseases in children by their third birthday. Notably, this beneficial effect seems even more pronounced when mercury exposure during pregnancy is lower.
While we also explored the interaction between selenium and mercury, the highlights of our results firmly place selenium in a positive light regarding its potential to mitigate allergy risks in early childhood.
Our findings point to a promising role for selenium: it appears to be linked with a reduced risk of atopic dermatitis, food allergies, allergic rhinitis, and overall allergic diseases in children by their third birthday. Notably, this beneficial effect seems even more pronounced when mercury exposure during pregnancy is lower.
While we also explored the interaction between selenium and mercury, the highlights of our results firmly place selenium in a positive light regarding its potential to mitigate allergy risks in early childhood.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.8
9.5
Effective against allergies
Great product! It is well absorbed and does not cause allergies. Thank you, iHerb!
9.5
Aids recovery
This helped with recovering from COVID-19 in conjunction with Zinc, vitamin C, and vitamin D. It did not trigger any allergies.
9.5
Highly recommended
đź‘Ť The doctor recommended this. Another brand caused an allergy, but this one is excellent.
9.5
Quality product
I have nothing negative to say about this product. After taking it for 10 days, I did not notice any signs of allergies, which is, for me, a sign of quality.
