Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
USERS' SCORE
Good
Based on 6 Reviews
8.4
Supplement Facts
Serving Size: 1 tablet
Amount Per Serving
%DV
Selenium (as L-selenomethionine)
100 mcg
182%
Top Medical Research Studies
9
We examined the impact of selenium supplements on thyroid autoantibody levels in patients with Hashimoto's thyroiditis.
In our analysis, selenium showed significant effectiveness in lowering both thyroid peroxidase and thyroglobulin autoantibodies compared to placebo.
However, other supplements like Vitamin D and Myo-inositol, including their combinations, did not demonstrate similar benefits over six months.
This suggests that including selenium might be a valuable addition to traditional treatments for individuals managing Hashimoto's.
In our analysis, selenium showed significant effectiveness in lowering both thyroid peroxidase and thyroglobulin autoantibodies compared to placebo.
However, other supplements like Vitamin D and Myo-inositol, including their combinations, did not demonstrate similar benefits over six months.
This suggests that including selenium might be a valuable addition to traditional treatments for individuals managing Hashimoto's.
Read More
9
We examined how selenium supplementation affects patients with autoimmune thyroid disease (AITD) by reviewing 17 randomized controlled trials involving nearly 2,000 participants.
The results revealed promising benefits; selenium significantly reduced levels of free triiodothyronine (FT3), free thyroxine (FT4), and anti-thyroid peroxidase antibodies (TPOAb).
However, thyroid-stimulating hormone (TSH) and anti-thyroglobulin antibody (TGAb) levels showed no significant changes. Overall, these findings indicate that selenium plays a crucial role in managing AITD.
The results revealed promising benefits; selenium significantly reduced levels of free triiodothyronine (FT3), free thyroxine (FT4), and anti-thyroid peroxidase antibodies (TPOAb).
However, thyroid-stimulating hormone (TSH) and anti-thyroglobulin antibody (TGAb) levels showed no significant changes. Overall, these findings indicate that selenium plays a crucial role in managing AITD.
Read More
8
We searched extensive studies to evaluate selenium supplementation's impact on Hashimoto thyroiditis (HT). Our analysis of 35 trials revealed that selenium can significantly lower TSH and thyroid antibodies in those not undergoing thyroid hormone replacement therapy. Despite these positive effects, there were no noticeable changes in thyroid hormone levels or other immune markers. Importantly, selenium was deemed safe, with no increased side effects compared to control groups. Overall, while selenium shows promise in managing certain aspects of HT, its effects on hormone production remain limited.
Read More
Most Useful Reviews
9
Balanced hormones
2 people found this helpful
It is crucial for my health. I have a thyroid issue (Hashimoto) but do not need to take additional hormone pills. Within 3-6 months, my hormone levels improved; I feel less tired and my weight is more balanced. My ultrasound showed that I no longer have thyroid nodules. The quality is excellent and the size is just right. Due to a lack of the iodine mineral, I use it daily.
Read More
9
Reduces inflammation
Selenium is a vital trace element influencing thyroid function. It possesses antioxidant properties that aid in reducing inflammation and enhancing thyroid function in thyroiditis. For autoimmune thyroiditis, like Hashimoto's disease, selenium can be beneficial as it lowers the antibodies that attack the thyroid gland and reduces inflammation. However, it is essential to consult your doctor before starting selenium treatments to ensure proper assessment and dosage.
Read More
7.5
Reduced blood glucose
2 people found this helpful
Easy to swallow, I take this for my Hashimoto’s hypothyroidism. My doctor informed me that studies in Europe suggest selenium can slow the progression of the disease. I need to take two pills each since I couldn't locate a 200mcg version. Thankfully, the pills are relatively small. I absolutely love this as it has reduced my fasting blood glucose by 30 points.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
- All Researches
9
We examined the impact of selenium supplements on thyroid autoantibody levels in patients with Hashimoto's thyroiditis.
In our analysis, selenium showed significant effectiveness in lowering both thyroid peroxidase and thyroglobulin autoantibodies compared to placebo.
However, other supplements like Vitamin D and Myo-inositol, including their combinations, did not demonstrate similar benefits over six months.
This suggests that including selenium might be a valuable addition to traditional treatments for individuals managing Hashimoto's.
In our analysis, selenium showed significant effectiveness in lowering both thyroid peroxidase and thyroglobulin autoantibodies compared to placebo.
However, other supplements like Vitamin D and Myo-inositol, including their combinations, did not demonstrate similar benefits over six months.
This suggests that including selenium might be a valuable addition to traditional treatments for individuals managing Hashimoto's.
Read More
9
We examined how selenium supplementation affects patients with autoimmune thyroid disease (AITD) by reviewing 17 randomized controlled trials involving nearly 2,000 participants.
The results revealed promising benefits; selenium significantly reduced levels of free triiodothyronine (FT3), free thyroxine (FT4), and anti-thyroid peroxidase antibodies (TPOAb).
However, thyroid-stimulating hormone (TSH) and anti-thyroglobulin antibody (TGAb) levels showed no significant changes. Overall, these findings indicate that selenium plays a crucial role in managing AITD.
The results revealed promising benefits; selenium significantly reduced levels of free triiodothyronine (FT3), free thyroxine (FT4), and anti-thyroid peroxidase antibodies (TPOAb).
However, thyroid-stimulating hormone (TSH) and anti-thyroglobulin antibody (TGAb) levels showed no significant changes. Overall, these findings indicate that selenium plays a crucial role in managing AITD.
Read More
8
We searched extensive studies to evaluate selenium supplementation's impact on Hashimoto thyroiditis (HT). Our analysis of 35 trials revealed that selenium can significantly lower TSH and thyroid antibodies in those not undergoing thyroid hormone replacement therapy. Despite these positive effects, there were no noticeable changes in thyroid hormone levels or other immune markers. Importantly, selenium was deemed safe, with no increased side effects compared to control groups. Overall, while selenium shows promise in managing certain aspects of HT, its effects on hormone production remain limited.
Read More
8
We explored the potential benefits of selenium supplementation for patients with Hashimoto thyroiditis (HT). In our systematic review of seven controlled trials with 342 participants, we found that while there was no notable change in thyroid peroxidase antibodies (TPOAb) levels after three months, there was a significant reduction in TPOAb and thyroglobulin antibodies (TgAb) levels after six months of treatment.
Although these findings indicate positive effects of selenium, further research is necessary to assess overall health quality and disease progression in HT patients.
Although these findings indicate positive effects of selenium, further research is necessary to assess overall health quality and disease progression in HT patients.
Read More
8
Selenium intake may reduce HT risk
We examined how dietary selenium influences Hashimoto's thyroiditis (HT) using data from the National Health and Nutrition Examination Survey, involving over 8,700 participants. The findings suggest that higher selenium intake is linked to a lower risk of developing HT.
We also noted a negative correlation between selenium and thyroid peroxidase antibodies, indicating that selenium might help manage this autoimmune condition effectively. This suggests that incorporating selenium into our diet could serve as a beneficial, affordable strategy for preventing and treating HT.
We also noted a negative correlation between selenium and thyroid peroxidase antibodies, indicating that selenium might help manage this autoimmune condition effectively. This suggests that incorporating selenium into our diet could serve as a beneficial, affordable strategy for preventing and treating HT.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Balanced hormones
2 people found this helpful
It is crucial for my health. I have a thyroid issue (Hashimoto) but do not need to take additional hormone pills. Within 3-6 months, my hormone levels improved; I feel less tired and my weight is more balanced. My ultrasound showed that I no longer have thyroid nodules. The quality is excellent and the size is just right. Due to a lack of the iodine mineral, I use it daily.
Read More
9
Reduces inflammation
Selenium is a vital trace element influencing thyroid function. It possesses antioxidant properties that aid in reducing inflammation and enhancing thyroid function in thyroiditis. For autoimmune thyroiditis, like Hashimoto's disease, selenium can be beneficial as it lowers the antibodies that attack the thyroid gland and reduces inflammation. However, it is essential to consult your doctor before starting selenium treatments to ensure proper assessment and dosage.
Read More
7.5
Reduced blood glucose
2 people found this helpful
Easy to swallow, I take this for my Hashimoto’s hypothyroidism. My doctor informed me that studies in Europe suggest selenium can slow the progression of the disease. I need to take two pills each since I couldn't locate a 200mcg version. Thankfully, the pills are relatively small. I absolutely love this as it has reduced my fasting blood glucose by 30 points.
Read More
9
Works wonderfully
I adore this product; it works wonderfully for my Hashimoto.
Read More
7.5
Good treatment assist
I purchased something to aid in the treatment of Hashimoto's, and the effects have been quite good. It surpasses the selenium yeast prescribed by the hospital, as Hashimoto's patients should avoid ingesting yeast.
Read More
Frequently Asked Questions
9
Balanced hormones
2 people found this helpful
It is crucial for my health. I have a thyroid issue (Hashimoto) but do not need to take additional hormone pills. Within 3-6 months, my hormone levels improved; I feel less tired and my weight is more balanced. My ultrasound showed that I no longer have thyroid nodules. The quality is excellent and the size is just right. Due to a lack of the iodine mineral, I use it daily.
7.5
Reduced blood glucose
2 people found this helpful
Easy to swallow, I take this for my Hashimoto’s hypothyroidism. My doctor informed me that studies in Europe suggest selenium can slow the progression of the disease. I need to take two pills each since I couldn't locate a 200mcg version. Thankfully, the pills are relatively small. I absolutely love this as it has reduced my fasting blood glucose by 30 points.
9
Reduces inflammation
Selenium is a vital trace element influencing thyroid function. It possesses antioxidant properties that aid in reducing inflammation and enhancing thyroid function in thyroiditis. For autoimmune thyroiditis, like Hashimoto's disease, selenium can be beneficial as it lowers the antibodies that attack the thyroid gland and reduces inflammation. However, it is essential to consult your doctor before starting selenium treatments to ensure proper assessment and dosage.
7.5
Good treatment assist
I purchased something to aid in the treatment of Hashimoto's, and the effects have been quite good. It surpasses the selenium yeast prescribed by the hospital, as Hashimoto's patients should avoid ingesting yeast.
9
We examined the impact of selenium supplements on thyroid autoantibody levels in patients with Hashimoto's thyroiditis.
In our analysis, selenium showed significant effectiveness in lowering both thyroid peroxidase and thyroglobulin autoantibodies compared to placebo.
However, other supplements like Vitamin D and Myo-inositol, including their combinations, did not demonstrate similar benefits over six months.
This suggests that including selenium might be a valuable addition to traditional treatments for individuals managing Hashimoto's.
In our analysis, selenium showed significant effectiveness in lowering both thyroid peroxidase and thyroglobulin autoantibodies compared to placebo.
However, other supplements like Vitamin D and Myo-inositol, including their combinations, did not demonstrate similar benefits over six months.
This suggests that including selenium might be a valuable addition to traditional treatments for individuals managing Hashimoto's.
7
We examined the impact of selenium supplementation on autoimmune thyroiditis (AIT) by assessing data from various databases. Although findings indicated a potential reduction in thyroid peroxidase antibodies (TPO-Ab) and thyroglobulin antibodies (Tg-Ab) at three and six months for those not treated with levothyroxine (LT4), the certainty of this evidence remains low.
In contrast, the effects on those treated with LT4 were mixed, with some antibody levels showing improvement. However, the overall conclusion suggests that while selenium might offer some benefits, the evidence isn’t strong enough to make definitive claims.
In contrast, the effects on those treated with LT4 were mixed, with some antibody levels showing improvement. However, the overall conclusion suggests that while selenium might offer some benefits, the evidence isn’t strong enough to make definitive claims.
8
We explored the potential benefits of selenium supplementation for patients with Hashimoto thyroiditis (HT). In our systematic review of seven controlled trials with 342 participants, we found that while there was no notable change in thyroid peroxidase antibodies (TPOAb) levels after three months, there was a significant reduction in TPOAb and thyroglobulin antibodies (TgAb) levels after six months of treatment.
Although these findings indicate positive effects of selenium, further research is necessary to assess overall health quality and disease progression in HT patients.
Although these findings indicate positive effects of selenium, further research is necessary to assess overall health quality and disease progression in HT patients.
8
We searched extensive studies to evaluate selenium supplementation's impact on Hashimoto thyroiditis (HT). Our analysis of 35 trials revealed that selenium can significantly lower TSH and thyroid antibodies in those not undergoing thyroid hormone replacement therapy. Despite these positive effects, there were no noticeable changes in thyroid hormone levels or other immune markers. Importantly, selenium was deemed safe, with no increased side effects compared to control groups. Overall, while selenium shows promise in managing certain aspects of HT, its effects on hormone production remain limited.
8
Selenium intake may reduce HT risk
We examined how dietary selenium influences Hashimoto's thyroiditis (HT) using data from the National Health and Nutrition Examination Survey, involving over 8,700 participants. The findings suggest that higher selenium intake is linked to a lower risk of developing HT.
We also noted a negative correlation between selenium and thyroid peroxidase antibodies, indicating that selenium might help manage this autoimmune condition effectively. This suggests that incorporating selenium into our diet could serve as a beneficial, affordable strategy for preventing and treating HT.
We also noted a negative correlation between selenium and thyroid peroxidase antibodies, indicating that selenium might help manage this autoimmune condition effectively. This suggests that incorporating selenium into our diet could serve as a beneficial, affordable strategy for preventing and treating HT.
8
We explored the role of selenium supplementation in patients with autoimmune thyroiditis (AIT). Although selenium is widely prescribed by endocrinologists in Europe, we found the existing evidence suggests mixed benefits.
Selenium may help reduce symptoms, lower thyroid autoantibodies, and improve the quality of life for many, including pregnant women by lowering risks of complications. However, the balance is crucial, as both deficiency and excess can negatively impact health.
More research is necessary to develop thorough guidelines for safe selenium use in different patient populations.
Selenium may help reduce symptoms, lower thyroid autoantibodies, and improve the quality of life for many, including pregnant women by lowering risks of complications. However, the balance is crucial, as both deficiency and excess can negatively impact health.
More research is necessary to develop thorough guidelines for safe selenium use in different patient populations.
4
We explored the effects of selenium supplementation on patients with chronic autoimmune thyroiditis (also known as Hashimoto's disease). We reviewed 23 studies that compared selenium use alongside standard treatment versus a placebo. While selenium appeared to reduce autoantibody levels, it did not significantly impact thyroid-stimulating hormone levels.
Ultimately, despite some positive findings, the overall evidence does not support the routine use of selenium in managing Hashimoto's disease, particularly given the potential for adverse effects.
Ultimately, despite some positive findings, the overall evidence does not support the routine use of selenium in managing Hashimoto's disease, particularly given the potential for adverse effects.
8
We evaluated how selenium supplementation might help patients with Hashimoto's thyroiditis (HT) in a structured study. Patients were split into two groups: one received selenium tablets for six months, while the other did not.
Results indicated that those taking selenium had lower levels of thyroid autoantibodies and improved thyroid function. Additionally, we noticed a rise in certain regulatory T cells, which may play a role in managing thyroid autoimmunity. Overall, selenium seems promising, especially for those with milder forms of HT.
Results indicated that those taking selenium had lower levels of thyroid autoantibodies and improved thyroid function. Additionally, we noticed a rise in certain regulatory T cells, which may play a role in managing thyroid autoimmunity. Overall, selenium seems promising, especially for those with milder forms of HT.
9
We examined how selenium supplementation affects patients with autoimmune thyroid disease (AITD) by reviewing 17 randomized controlled trials involving nearly 2,000 participants.
The results revealed promising benefits; selenium significantly reduced levels of free triiodothyronine (FT3), free thyroxine (FT4), and anti-thyroid peroxidase antibodies (TPOAb).
However, thyroid-stimulating hormone (TSH) and anti-thyroglobulin antibody (TGAb) levels showed no significant changes. Overall, these findings indicate that selenium plays a crucial role in managing AITD.
The results revealed promising benefits; selenium significantly reduced levels of free triiodothyronine (FT3), free thyroxine (FT4), and anti-thyroid peroxidase antibodies (TPOAb).
However, thyroid-stimulating hormone (TSH) and anti-thyroglobulin antibody (TGAb) levels showed no significant changes. Overall, these findings indicate that selenium plays a crucial role in managing AITD.
4
We examined how selenium affects women newly diagnosed with Hashimoto's thyroiditis by supplementing them with 100 µg a day for six months.
Throughout this time, we tracked changes in various immune markers, focusing on cytokine production.
Interestingly, selenium appeared to influence two specific cytokines: we observed a decrease in interferon γ and an increase in interleukin 1β.
While this suggests selenium might have a role in altering immune responses, more research is needed to fully understand its effects on thyroid function.
Throughout this time, we tracked changes in various immune markers, focusing on cytokine production.
Interestingly, selenium appeared to influence two specific cytokines: we observed a decrease in interferon γ and an increase in interleukin 1β.
While this suggests selenium might have a role in altering immune responses, more research is needed to fully understand its effects on thyroid function.
8
We explored the impacts of selenium supplementation on patients with Hashimoto's thyroiditis, a common autoimmune condition. After studying 100 participants over six months, we found that those who received 200 micrograms of selenium yeast showed an improvement in their selenium levels.
Most importantly, we observed a significant reduction in thyroid antibodies, TGAb and TPOAb, suggesting that selenium may help manage this condition by lowering these autoantibodies. While selenium deficiency was common initially, supplementation appears beneficial in these patients.
Most importantly, we observed a significant reduction in thyroid antibodies, TGAb and TPOAb, suggesting that selenium may help manage this condition by lowering these autoantibodies. While selenium deficiency was common initially, supplementation appears beneficial in these patients.
References
- Peng B, Wang W, Gu Q, Wang P, Teng W, et al. Effects of different supplements on Hashimoto's thyroiditis: a systematic review and network meta-analysis. Front Endocrinol (Lausanne). 2024;15:1445878. doi:10.3389/fendo.2024.1445878
- Huwiler VV, Maissen-Abgottspon S, Stanga Z, Mühlebach S, Trepp R, et al. Selenium Supplementation in Patients with Hashimoto Thyroiditis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Thyroid. 2024;34:295. doi:10.1089/thy.2023.0556
- Wang W, Jiang QL, Xu Q, Zeng Y, Jiang R, et al. Selenium regulates T cell differentiation in experimental autoimmune thyroiditis in mice. Int Immunopharmacol. 2023;124:110993. doi:10.1016/j.intimp.2023.110993
- Wang YS, Liang SS, Ren JJ, Wang ZY, Deng XX, et al. The Effects of Selenium Supplementation in the Treatment of Autoimmune Thyroiditis: An Overview of Systematic Reviews. Nutrients. 2023;15. doi:10.3390/nu15143194
- Kong XQ, Qiu GY, Yang ZB, Tan ZX, Quan XQ. Clinical efficacy of selenium supplementation in patients with Hashimoto thyroiditis: A systematic review and meta-analysis. Medicine (Baltimore). 2023;102:e33791. doi:10.1097/MD.0000000000033791
- Zheng G, Cai Y, Guo Y, Song F, Hu Y, et al. The association between dietary selenium intake and Hashimoto's thyroiditis among US adults: National Health and Nutrition Examination Survey (NHANES), 2007-2012. J Endocrinol Invest. 2023;46:1385. doi:10.1007/s40618-022-01987-0
- Kryczyk-Kozioł J, Prochownik E, Błażewska-Gruszczyk A, Słowiaczek M, Sun Q, et al. Assessment of the Effect of Selenium Supplementation on Production of Selected Cytokines in Women with Hashimoto's Thyroiditis. Nutrients. 2022;14. doi:10.3390/nu14142869
- Wu Q, Wang Y, Chen P, Wei J, Lv H, et al. Increased Incidence of Hashimoto Thyroiditis in Selenium Deficiency: A Prospective 6-Year Cohort Study. J Clin Endocrinol Metab. 2022;107:e3603. doi:10.1210/clinem/dgac410
- Minnetti M, Sada V, Feola T, Giannetta E, Pozza C, et al. Selenium Supplementation in Pregnant Women with Autoimmune Thyroiditis: A Practical Approach. Nutrients. 2022;14. doi:10.3390/nu14112234
- Wang LF, Sun RX, Li CF, Wang XH. The effects of selenium supplementation on antibody titres in patients with Hashimoto's thyroiditis. Endokrynol Pol. 2021;72:666. doi:10.5603/EP.a2021.0074
- Kryczyk-Kozioł J, Zagrodzki P, Prochownik E, Błażewska-Gruszczyk A, Słowiaczek M, et al. Positive effects of selenium supplementation in women with newly diagnosed Hashimoto's thyroiditis in an area with low selenium status. Int J Clin Pract. 2021;75:e14484. doi:10.1111/ijcp.14484
- Filipowicz D, Majewska K, Kalantarova A, Szczepanek-Parulska E, Ruchała M. The rationale for selenium supplementation in patients with autoimmune thyroiditis, according to the current state of knowledge. Endokrynol Pol. 2021;72:153. doi:10.5603/EP.a2021.0017
- Zuo Y, Li Y, Gu X, Lei Z. The correlation between selenium levels and autoimmune thyroid disease: a systematic review and meta-analysis. Ann Palliat Med. 2021;10:4398. doi:10.21037/apm-21-449
- Qiu Y, Xing Z, Xiang Q, Yang Q, Zhu J, et al. Insufficient evidence to support the clinical efficacy of selenium supplementation for patients with chronic autoimmune thyroiditis. Endocrine. 2021;73:384. doi:10.1007/s12020-021-02642-z
- Hu Y, Feng W, Chen H, Shi H, Jiang L, et al. Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto's thyroiditis: A prospective randomized-controlled trial. Clin Transl Sci. 2021;14:1390. doi:10.1111/cts.12993
- Pace C, Tumino D, Russo M, Le Moli R, Naselli A, et al. Role of selenium and myo-inositol supplementation on autoimmune thyroiditis progression. Endocr J. 2020;67:1093. doi:10.1507/endocrj.EJ20-0062
