Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.3
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.8
Supplement Facts
Serving Size: 4 capsules
Amount Per Serving
%DV
Vitamin D (as ergocalciferol)
10 mcg (400 I.U.)
50%
Calcium (as calcium hydroxyapatite, calcium citrate, calcium aspartate)â€
1,000 mg
77%
Phosphorus (as calcium hydroxyapatite)â€
500 mg
40%
Magnesium (as magnesium oxide, magnesium aspartate, magnesium citrate, magnesium taurinate)â€
500 mg
119%
Top Medical Research Studies
8
Vitamin D and nausea in gastroparesis
We delved into an intriguing question: how do low vitamin D levels affect nausea in people experiencing gastroparesis, a condition that slows gastric emptying? By measuring the vitamin D levels of patients from the Gastroparesis Clinical Consortium Registry, we aimed to uncover the relationships between vitamin D, nausea, and gastric function.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Read More
8
We conducted a study to discover how magnesium sulfate affects nausea during orthognathic surgery. In this research, we divided 75 adult patients into two groups: one group received magnesium sulfate, while the other received a placebo saline solution.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
Read More
5
We explored how vitamin D levels affect nausea and other premenstrual symptoms (PMS) while considering the influence of genetics. Our study involved 716 women between the ages of 20 and 29, who provided blood samples to measure their vitamin D status and completed questionnaires about their PMS experiences.
By classifying participants as either vitamin D sufficient or insufficient based on their plasma levels, we examined how these levels correlated with nausea, alongside a specific genetic variation in the vitamin D receptor gene. Interestingly, we found that women with the CC genotype who had low vitamin D levels were more likely to experience nausea, whereas those with the TT genotype exhibited a low likelihood of suffering from nausea under similar conditions.
Overall, we can say that vitamin D's impact on nausea does not occur in isolation; it is modified by genetic factors. This highlights the importance of considering both vitamin D status and genetic background when trying to understand the factors contributing to PMS symptoms like nausea.
By classifying participants as either vitamin D sufficient or insufficient based on their plasma levels, we examined how these levels correlated with nausea, alongside a specific genetic variation in the vitamin D receptor gene. Interestingly, we found that women with the CC genotype who had low vitamin D levels were more likely to experience nausea, whereas those with the TT genotype exhibited a low likelihood of suffering from nausea under similar conditions.
Overall, we can say that vitamin D's impact on nausea does not occur in isolation; it is modified by genetic factors. This highlights the importance of considering both vitamin D status and genetic background when trying to understand the factors contributing to PMS symptoms like nausea.
Read More
Most Useful Reviews
0
Immediate nausea reaction
1 people found this helpful
Causes nausea, buyer beware. Immediately after taking my first dose, I felt nauseous to the point of considering a trip to the ER. I reached out to the seller, but they only suggested I return the item. I recommend paying a bit more for a quality brand to avoid a potential nausea episode.
Read More
9
No nausea experienced
This remedy does not induce nausea as the pharmacy "Nycomed" does. While some may prefer capsules, I favour the tablets from the same manufacturer. Each capsule contains 250 mg of calcium, making it easy to split the dosage. I appreciate the combination with magnesium, necessary for supporting the nervous system, alongside a small dose of Vitamin D. With a consistent intake, this drug has proven to be the best choice for me personally. It contains no sugar or unnecessary ingredients, which I find appealing. I take it with food due to a sensitive gastrointestinal tract. Highly recommended! This is my third time using it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.3
- All Researches
9
We explored the effects of a low-opioid anesthesia (LOA) protocol during laparoscopic cholecystectomy and its impact on nausea, vomiting, and pain control. In our study, we compared 40 patients who received LOA, which included magnesium sulfate, with another 40 patients who were given standard opioid-based anesthesia.
While our findings showed that the LOA protocol was more effective in reducing nausea and vomiting compared to traditional opioid analgesia, we didn’t isolate magnesium’s specific role in this improvement. This limitation makes it challenging to determine just how much magnesium alone contributes to reducing nausea.
Nevertheless, the study suggests that using a low-opioid method can enhance patient comfort in the postoperative period. Overall, we found that incorporating non-opioid analgesia and the LOA strategy should be considered more widely in surgical practices.
While our findings showed that the LOA protocol was more effective in reducing nausea and vomiting compared to traditional opioid analgesia, we didn’t isolate magnesium’s specific role in this improvement. This limitation makes it challenging to determine just how much magnesium alone contributes to reducing nausea.
Nevertheless, the study suggests that using a low-opioid method can enhance patient comfort in the postoperative period. Overall, we found that incorporating non-opioid analgesia and the LOA strategy should be considered more widely in surgical practices.
Read More
8
Vitamin D and nausea in gastroparesis
We delved into an intriguing question: how do low vitamin D levels affect nausea in people experiencing gastroparesis, a condition that slows gastric emptying? By measuring the vitamin D levels of patients from the Gastroparesis Clinical Consortium Registry, we aimed to uncover the relationships between vitamin D, nausea, and gastric function.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Our findings revealed that over half of the patients had low vitamin D levels, specifically 56.1% of the 513 individuals studied. We observed a clear association between these low levels of vitamin D and increased experiences of nausea and vomiting. This was particularly notable in patients with delayed gastric emptying, where those with low vitamin D levels reported significantly more nausea.
While the study showed a correlation, it did not address whether supplementing with vitamin D could directly alleviate these symptoms. Instead, we found that lower vitamin D levels also related to a greater retention of food in the stomach after meals, which hints at a connection to gastric neuromuscular dysfunction. Overall, our study emphasized a noteworthy link between vitamin D and nausea but stopped short of confirming any direct treatment benefits.
Read More
8
We conducted a study to discover how magnesium sulfate affects nausea during orthognathic surgery. In this research, we divided 75 adult patients into two groups: one group received magnesium sulfate, while the other received a placebo saline solution.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
Read More
We conducted a thorough investigation into how combining oral pregabalin and intravenous magnesium sulfate influences nausea in patients undergoing a specific type of spine surgery. In a well-structured trial, 104 participants were randomly assigned to one of four groups, where some received magnesium sulfate with pregabalin, while others received either a placebo or just one of the drugs.
Our primary focus was on how much morphine the patients needed on the first day after surgery, which gives us insight into their pain levels. While we noted the overall benefits of combining these two non-opioid treatments for pain relief, the study did mention postoperative nausea and vomiting as secondary outcomes. However, it's important to clarify that the findings did not specifically highlight any significant advantages of magnesium in reducing nausea when compared to the other treatments or placebos.
In essence, while we observed that the combination of magnesium sulfate and pregabalin effectively reduced opioid consumption and improved pain management post-surgery, it did not yield clear evidence pointing to magnesium's effectiveness specifically for alleviating nausea. This nuanced insight is valuable as we continue exploring the best strategies for managing multiple aspects of patient comfort during the recovery process.
Our primary focus was on how much morphine the patients needed on the first day after surgery, which gives us insight into their pain levels. While we noted the overall benefits of combining these two non-opioid treatments for pain relief, the study did mention postoperative nausea and vomiting as secondary outcomes. However, it's important to clarify that the findings did not specifically highlight any significant advantages of magnesium in reducing nausea when compared to the other treatments or placebos.
In essence, while we observed that the combination of magnesium sulfate and pregabalin effectively reduced opioid consumption and improved pain management post-surgery, it did not yield clear evidence pointing to magnesium's effectiveness specifically for alleviating nausea. This nuanced insight is valuable as we continue exploring the best strategies for managing multiple aspects of patient comfort during the recovery process.
Read More
7
Magnesium reduces post-operative nausea
In our exploration of how magnesium treatment influences nausea, we conducted a double-blind clinical trial with 62 children undergoing tonsillectomy. Participants were divided into two groups, where one received magnesium sulfate and the other lidocaine shortly after intubation.
We observed that while both medications were used, magnesium sulfate appeared to offer benefits over lidocaine. Notably, the group receiving magnesium experienced a significantly lower rate of nausea and vomiting compared to those treated with lidocaine. This points to magnesium's potential effectiveness in managing post-operative nausea.
However, it’s essential to note that our study did not find any significant difference in terms of laryngospasm incidence between the two groups. Overall, magnesium sulfate showcased an advantage with fewer instances of nausea and other distressing symptoms, suggesting its role as a valuable option for patient care in similar surgical scenarios.
We observed that while both medications were used, magnesium sulfate appeared to offer benefits over lidocaine. Notably, the group receiving magnesium experienced a significantly lower rate of nausea and vomiting compared to those treated with lidocaine. This points to magnesium's potential effectiveness in managing post-operative nausea.
However, it’s essential to note that our study did not find any significant difference in terms of laryngospasm incidence between the two groups. Overall, magnesium sulfate showcased an advantage with fewer instances of nausea and other distressing symptoms, suggesting its role as a valuable option for patient care in similar surgical scenarios.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
0
Immediate nausea reaction
1 people found this helpful
Causes nausea, buyer beware. Immediately after taking my first dose, I felt nauseous to the point of considering a trip to the ER. I reached out to the seller, but they only suggested I return the item. I recommend paying a bit more for a quality brand to avoid a potential nausea episode.
Read More
9
No nausea experienced
This remedy does not induce nausea as the pharmacy "Nycomed" does. While some may prefer capsules, I favour the tablets from the same manufacturer. Each capsule contains 250 mg of calcium, making it easy to split the dosage. I appreciate the combination with magnesium, necessary for supporting the nervous system, alongside a small dose of Vitamin D. With a consistent intake, this drug has proven to be the best choice for me personally. It contains no sugar or unnecessary ingredients, which I find appealing. I take it with food due to a sensitive gastrointestinal tract. Highly recommended! This is my third time using it.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Koch KL, Parkman HP, Yates KP, Van Natta ML, Grover M, et al. Low Vitamin D Levels in Patients with Symptoms of Gastroparesis: Relationships with Nausea and Vomiting, Gastric Emptying and Gastric Myoelectrical Activity. Dig Dis Sci. 2024;69:2904. doi:10.1007/s10620-024-08520-8
- Jarosz AC, Noori D, Zeitoun T, Garcia-Bailo B, El-Sohemy A. Variation in the vitamin D receptor gene, plasma 25-hydroxyvitamin D, and risk of premenstrual symptoms. Genes Nutr. 2021;16:15. doi:10.1186/s12263-021-00696-2
- Hua X, Chen Y, Wu Z, Zheng G, Yang D, et al. Effects of intra-operative magnesium sulfate infusion on orthognathic surgery: A prospective and randomized controlled trial. Heliyon. 2024;10:e30342. doi:10.1016/j.heliyon.2024.e30342
- Kościuczuk U, Tarnowska K, Rynkiewicz-Szczepanska E. Are There Any Advantages of the Low Opioid Anaesthesia and Non-Opioid Postoperative Analgesia Protocol: A Clinical Observational Study. J Pain Res. 2024;17:941. doi:10.2147/JPR.S449563
- Tavanaei R, Rezaee-Naserabad SS, Alizadeh S, Yazdani KO, Zali A, et al. Analgesic Effects of Preoperative Combination of Oral Pregabalin and Intravenous Magnesium Sulfate on Postoperative Pain in Patients Undergoing Posterolateral Spinal Fusion Surgery: A 4-arm, Randomized, Double-blind, Placebo-controlled Trial. J Neurosurg Anesthesiol. 2024;36:134. doi:10.1097/ANA.0000000000000893
- Manouchehrian N, Abbasi R, Jiryaee N, Beigi RM. Comparison of intravenous injection of magnesium sulfate and lidocaine effectiveness on the prevention of laryngospasm and analgesic requirement in tonsillectomy. Eur J Transl Myol. 2022;32. doi:10.4081/ejtm.2022.10732
