I don't use these for urinary tract infection. I use these mostly for irritated kidneys and bladder that you can sometimes get when you take supplements. My diet was very poor for a long time and I became deficient in vitamin D and several other vitamins that my body really needs. The problem with me is that I have always had very sensitive kidneys and a very sensitive bladder from the time I was a kid. While all my soda loving Southern relatives were drinking soda pop by the gallon when I was little, I would always ask for water because even when I was little if I drank too much soda, I would feel that familiar irritation in my bladder and lower Back pain. As an adult, whenever I take multiple vitamin supplements or have too much tea or coffee, by the end of the day I can feel that familiar pain in my lower back and that tingling sensation in my bladder that lets me know that they are inflamed. I would have to drink pure water for a day or two and cease all supplements. According to my doctor, my kidney function is fine. I don't have stones. I just have a body that responds with disapproval when I take multiple supplements (at USRDA) or have too much caffeine! But right now, I need the the supplements and I can't bear the thought of parting with my morning coffee. I take 2 of these every night. I started taking them a couple weeks ago. From the first night, all the symptoms of irritated kidneys and bladder resolved for me by the very next day and have not returned. Not a bad price and I don't get extra sugar from drinking cranberry juice -- which I don't love enough to drink every day. I get the antioxidants plus bladder and kidney support. It's a win-win