Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
USERS' SCORE
Good
Based on 6 Reviews
8.8
Supplement Facts
Serving Size: Two (2) softgels
Amount Per Serving
%DV
Calories
10
 
Total Fat
1 g
1%**
Total Carbohydrate
<1 g
<1%**
Vitamin C (as ascorbic acid)
120 mg
133%
Pacran® Whole Fruit Cranberry (Vaccinium macrocarpon) 
500 mg

Top Medical Research Studies

9
Vitamin C aids ear infection recovery
We observed that malignant external otitis (MEO), a severe infection of the outer ear often found in elderly patients with uncontrolled diabetes, can significantly impair the body's defense mechanisms. In a notable case, a 58-year-old man struggling with MEO had faced months of ineffective treatments.

To delve deeper, we tested the function of his immune cells, specifically his polymorphonuclear neutrophil leukocytes (PMNs), which play a crucial role in fighting infections. Our findings revealed that his PMNs had difficulty migrating to the site of infection, a critical step for addressing such health issues.

We discovered that ascorbic acid, commonly known as vitamin C, could improve this migration defect in laboratory tests. In practical terms, after just one month of vitamin C treatment, the patient's chemotaxis results normalized, and remarkably, his ear lesions began to heal.

Even though the exact reasons for the PMN dysfunction remain unclear, possibly due to factors like age and diabetes, this case highlights the importance of assessing PMN function in MEO patients and suggests that immunomodulators like vitamin C might offer a valuable treatment pathway.
Read More
9
Vitamin C aids ear infection recovery
We explored the effects of vitamin C, alongside other antioxidants, in the treatment of ear infections in children, particularly focusing on middle ear inflammation. The study aimed to determine if these antioxidants could significantly enhance recovery from what can be quite painful and distressing conditions like purulent inflammation of the middle ear.

Through the trial, we combined ascorbic acid with retinol and alpha-tocopherol as part of a combined treatment approach. The results were promising, showing a high response rate in children suffering from these infections. This suggests that vitamin C and the other antioxidants may play a beneficial role in supporting the healing process.

Overall, the findings indicate that incorporating antioxidants like vitamin C into treatment regimens could potentially improve outcomes for young patients dealing with ear infections. While further research is necessary to confirm these benefits definitively, the initial results are encouraging and highlight an interesting avenue for more effective treatments.
Read More
8
Pediatric ear infection treatment study
We evaluated the effects of a herbal compound that includes Vitamin C, among other ingredients, on recurrent upper respiratory tract infections in children. The study involved 37 kids suffering from conditions like pharyngotonsillitis and otitis media. The children received a treatment called Imoviral® Junior, which is a blend of Echinacea angustifolia, Arabinogalactan, Beta-Glucan, and Zinc, alongside Vitamin C.

Results showed that before treatment, children had an average of 3 inflammatory episodes over six months, which dropped to just 1. After completing the treatment, 77% of the children reported fewer episodes of inflammation. Additionally, their quality of life scores improved significantly. Importantly, there were no reported side effects from using this herbal compound, indicating a safe alternative for managing these conditions.

While this study demonstrates promising outcomes regarding the frequency of ear infections with the use of Vitamin C as part of an herbal blend, we should note that it does not provide specific insights into Vitamin C's individual role on its own. Considering that other compounds were also involved, isolating the effects of Vitamin C alone remains a challenge.
Read More

Most Useful Reviews

9.5
Pain relief achieved
This product works for me. I've dealt with bladder infections, UTIs, and yeast for over a year, trying numerous prescriptions for pain and antibiotics for infection. After taking cranberry pills, especially this one, I noticed a significant improvement. Initially sceptical, I began feeling the positive effects after two weeks. I no longer experience frequent urges to urinate, pain during urination, or pressure in my lower abdomen. This pill has spared me another trip to the doctor and saved me money.
Read More
9.5
Bladder health improved
A must-have for life. I originally thought I had OAB. I started noticing that the urgency and pain were, in fact, due to a UTI and bladder infection. I started taking 2 of these with the AZO UTI pain relief pills and for the first time in weeks, I could relax. After finishing the AZO pills, I went to my doctor, who found my UTI/bladder infection had cleared up. My doctor and I discussed that taking 2 of these cranberry pills daily would benefit my bladder issues. It's now over a month later, and I'm sleeping through the night with no UTIs or bladder infections. These have truly helped me and I don't intend to stop taking them.
Read More
8.8
Reduced UTI symptoms
Nobody likes having urinary tract infections, and I've experienced them for over a decade. Recently, I discovered my difficulties were due to an enlarged prostate, which prevented me from emptying my bladder. Following a friend's recommendation, I tried AZO, which I found reduces both the urgency and burning sensations associated with UTIs. While I'm unsure about continuing it after an antibiotic gets rid of the UTI, it may help with frequency issues.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
  • All Researches
9
Vitamin C aids ear infection recovery
We explored the effects of vitamin C, alongside other antioxidants, in the treatment of ear infections in children, particularly focusing on middle ear inflammation. The study aimed to determine if these antioxidants could significantly enhance recovery from what can be quite painful and distressing conditions like purulent inflammation of the middle ear.

Through the trial, we combined ascorbic acid with retinol and alpha-tocopherol as part of a combined treatment approach. The results were promising, showing a high response rate in children suffering from these infections. This suggests that vitamin C and the other antioxidants may play a beneficial role in supporting the healing process.

Overall, the findings indicate that incorporating antioxidants like vitamin C into treatment regimens could potentially improve outcomes for young patients dealing with ear infections. While further research is necessary to confirm these benefits definitively, the initial results are encouraging and highlight an interesting avenue for more effective treatments.
Read More
9
Vitamin C aids ear infection recovery
We observed that malignant external otitis (MEO), a severe infection of the outer ear often found in elderly patients with uncontrolled diabetes, can significantly impair the body's defense mechanisms. In a notable case, a 58-year-old man struggling with MEO had faced months of ineffective treatments.

To delve deeper, we tested the function of his immune cells, specifically his polymorphonuclear neutrophil leukocytes (PMNs), which play a crucial role in fighting infections. Our findings revealed that his PMNs had difficulty migrating to the site of infection, a critical step for addressing such health issues.

We discovered that ascorbic acid, commonly known as vitamin C, could improve this migration defect in laboratory tests. In practical terms, after just one month of vitamin C treatment, the patient's chemotaxis results normalized, and remarkably, his ear lesions began to heal.

Even though the exact reasons for the PMN dysfunction remain unclear, possibly due to factors like age and diabetes, this case highlights the importance of assessing PMN function in MEO patients and suggests that immunomodulators like vitamin C might offer a valuable treatment pathway.
Read More
8
Pediatric ear infection treatment study
We evaluated the effects of a herbal compound that includes Vitamin C, among other ingredients, on recurrent upper respiratory tract infections in children. The study involved 37 kids suffering from conditions like pharyngotonsillitis and otitis media. The children received a treatment called Imoviral® Junior, which is a blend of Echinacea angustifolia, Arabinogalactan, Beta-Glucan, and Zinc, alongside Vitamin C.

Results showed that before treatment, children had an average of 3 inflammatory episodes over six months, which dropped to just 1. After completing the treatment, 77% of the children reported fewer episodes of inflammation. Additionally, their quality of life scores improved significantly. Importantly, there were no reported side effects from using this herbal compound, indicating a safe alternative for managing these conditions.

While this study demonstrates promising outcomes regarding the frequency of ear infections with the use of Vitamin C as part of an herbal blend, we should note that it does not provide specific insights into Vitamin C's individual role on its own. Considering that other compounds were also involved, isolating the effects of Vitamin C alone remains a challenge.
Read More

User Reviews

USERS' SCORE
Good
Based on 6 Reviews
8.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Pain relief achieved
This product works for me. I've dealt with bladder infections, UTIs, and yeast for over a year, trying numerous prescriptions for pain and antibiotics for infection. After taking cranberry pills, especially this one, I noticed a significant improvement. Initially sceptical, I began feeling the positive effects after two weeks. I no longer experience frequent urges to urinate, pain during urination, or pressure in my lower abdomen. This pill has spared me another trip to the doctor and saved me money.
Read More
9.5
Bladder health improved
A must-have for life. I originally thought I had OAB. I started noticing that the urgency and pain were, in fact, due to a UTI and bladder infection. I started taking 2 of these with the AZO UTI pain relief pills and for the first time in weeks, I could relax. After finishing the AZO pills, I went to my doctor, who found my UTI/bladder infection had cleared up. My doctor and I discussed that taking 2 of these cranberry pills daily would benefit my bladder issues. It's now over a month later, and I'm sleeping through the night with no UTIs or bladder infections. These have truly helped me and I don't intend to stop taking them.
Read More
8.8
Reduced UTI symptoms
Nobody likes having urinary tract infections, and I've experienced them for over a decade. Recently, I discovered my difficulties were due to an enlarged prostate, which prevented me from emptying my bladder. Following a friend's recommendation, I tried AZO, which I found reduces both the urgency and burning sensations associated with UTIs. While I'm unsure about continuing it after an antibiotic gets rid of the UTI, it may help with frequency issues.
Read More
7.5
Minimized UTI occurrences
AZO effectively manages urinary tract infections for my elderly mother. She has persistent UTIs, and AZO helps keep them at bay. She swears by it.
Read More
8.8
My preferred choice
This product has been my go-to for nearly a year due to my tendency for urinary tract infections. I appreciate its easy-to-swallow formula and pleasant flavour, which helps relieve discomfort and protect against UTIs. It certainly saves unnecessary hospital visits.
Read More

Frequently Asked Questions

An ear infection, also known as otitis media, occurs when germs—such as bacteria or viruses—infect the middle ear, which is the space behind the eardrum. This condition can cause a variety of symptoms, including ear pain, difficulty hearing, fluid drainage from the ear, fever, and irritability in children. Ear infections are particularly common in children due to their shorter and more horizontal Eustachian tubes, which make it easier for pathogens to reach the middle ear. When the Eustachian tubes become swollen or blocked due to upper respiratory infections, allergies, or sinus infections, fluid can accumulate and lead to an infection.

Treatment typically depends on the severity and frequency of the infections. For mild cases, doctors may recommend observation, as many ear infections resolve on their own. In more severe cases, particularly when symptoms last longer than 48 hours, antibiotics may be prescribed. Pain relievers can also help manage discomfort. In cases of recurrent infections, additional interventions, such as the placement of ear tubes, might be considered. Proper hygiene and avoiding exposure to smoke can also reduce the risk of developing ear infections.

Cranberries are small, round, red berries that belong to the family Ericaceae, specifically the genus Vaccinium. They are native to North America and are commonly found in acidic bogs in various regions of the United States and Canada. Known for their tart flavor, cranberries are often used in juices, sauces, and numerous culinary dishes. They are typically harvested during the fall, when they are at their peak ripeness, and are characterized by their bright color and firm texture.

Beyond their culinary uses, cranberries are also celebrated for their potential health benefits. They are rich in antioxidants, vitamins, and dietary fiber, which may contribute to heart health and help in the prevention of certain infections, particularly urinary tract infections (UTIs). Many people consider cranberry juice and extracts as natural remedies due to these properties. However, it's important to keep in mind that the sugar content in commercial cranberry beverages can be quite high, so opting for 100% pure cranberry juice or incorporating fresh cranberries into your diet can be a healthier choice. Overall, cranberries offer a delightful tartness while providing various nutritional benefits, making them a valued addition to both seasonal dishes and everyday meals.

Cranberry is often lauded for its potential health benefits, particularly in relation to urinary tract infections (UTIs), due to its high content of proanthocyanidins. However, its efficacy in treating ear infections is less clear. While cranberries may support overall immune health, there is no solid scientific evidence to suggest that consuming cranberry products can directly treat or prevent ear infections. For those experiencing ear infections, it's important to consult with a healthcare professional for appropriate medical guidance.

In general, ear infections are typically caused by bacteria or viruses, making them less susceptible to natural remedies alone. Standard treatments often include antibiotics for bacterial infections or pain relief methods. Natural options like cranberry juice may help in boosting overall health but should not be relied upon as a primary treatment for ear infections. Always consult with a healthcare provider to explore the most effective treatment options for your condition.

Recent research indicates that certain formulations containing Vitamin C may aid in alleviating symptoms related to ear infections, especially in pediatric cases. For instance, a study demonstrated that a herbal compound including Vitamin C significantly reduced the frequency of inflammatory episodes in children suffering from recurrent ear infections, with 77% of participants reporting fewer incidents after treatment [1]. Another study explored the effects of Vitamin C alongside other antioxidants in treating middle ear infections and found promising results, suggesting that antioxidants could enhance recovery rates [2].

Additionally, evidence suggests Vitamin C may play a role in improving immune response in individuals with chronic ear infections, such as malignant external otitis. A case study indicated that Vitamin C helped normalize the immune function of a patient after traditional treatments had failed, leading to healing of ear lesions [3]. While these findings are encouraging, it's important to note that more focused studies on Vitamin C's isolated effects are needed to firmly establish its efficacy for ear infections. Overall, while not conclusively proven on its own, the inclusion of Vitamin C in specific treatment regimens shows potential benefits for managing ear infections.

8
Pediatric ear infection treatment study
We evaluated the effects of a herbal compound that includes Vitamin C, among other ingredients, on recurrent upper respiratory tract infections in children. The study involved 37 kids suffering from conditions like pharyngotonsillitis and otitis media. The children received a treatment called Imoviral® Junior, which is a blend of Echinacea angustifolia, Arabinogalactan, Beta-Glucan, and Zinc, alongside Vitamin C.

Results showed that before treatment, children had an average of 3 inflammatory episodes over six months, which dropped to just 1. After completing the treatment, 77% of the children reported fewer episodes of inflammation. Additionally, their quality of life scores improved significantly. Importantly, there were no reported side effects from using this herbal compound, indicating a safe alternative for managing these conditions.

While this study demonstrates promising outcomes regarding the frequency of ear infections with the use of Vitamin C as part of an herbal blend, we should note that it does not provide specific insights into Vitamin C's individual role on its own. Considering that other compounds were also involved, isolating the effects of Vitamin C alone remains a challenge.
9
Vitamin C aids ear infection recovery
We explored the effects of vitamin C, alongside other antioxidants, in the treatment of ear infections in children, particularly focusing on middle ear inflammation. The study aimed to determine if these antioxidants could significantly enhance recovery from what can be quite painful and distressing conditions like purulent inflammation of the middle ear.

Through the trial, we combined ascorbic acid with retinol and alpha-tocopherol as part of a combined treatment approach. The results were promising, showing a high response rate in children suffering from these infections. This suggests that vitamin C and the other antioxidants may play a beneficial role in supporting the healing process.

Overall, the findings indicate that incorporating antioxidants like vitamin C into treatment regimens could potentially improve outcomes for young patients dealing with ear infections. While further research is necessary to confirm these benefits definitively, the initial results are encouraging and highlight an interesting avenue for more effective treatments.
9
Vitamin C aids ear infection recovery
We observed that malignant external otitis (MEO), a severe infection of the outer ear often found in elderly patients with uncontrolled diabetes, can significantly impair the body's defense mechanisms. In a notable case, a 58-year-old man struggling with MEO had faced months of ineffective treatments.

To delve deeper, we tested the function of his immune cells, specifically his polymorphonuclear neutrophil leukocytes (PMNs), which play a crucial role in fighting infections. Our findings revealed that his PMNs had difficulty migrating to the site of infection, a critical step for addressing such health issues.

We discovered that ascorbic acid, commonly known as vitamin C, could improve this migration defect in laboratory tests. In practical terms, after just one month of vitamin C treatment, the patient's chemotaxis results normalized, and remarkably, his ear lesions began to heal.

Even though the exact reasons for the PMN dysfunction remain unclear, possibly due to factors like age and diabetes, this case highlights the importance of assessing PMN function in MEO patients and suggests that immunomodulators like vitamin C might offer a valuable treatment pathway.

References

  1. Minetti AM, Forti S, Tassone G, Torretta S, Pignataro L. Efficacy of complex herbal compound of Echinacea angustifolia (Imoviral® Junior) in recurrent upper respiratory tract infections during pediatric age: preliminary results. Minerva Pediatr. 2011;63:177.
  2. Karabaev KE, Antoniv VF, Bekmuradov RU. [Pathogenetic validation of optimal antioxidant therapy in suppurative inflammatory otic diseases in children]. Vestn Otorinolaringol. 1997.
  3. Corberand J, Nguyen F, Fraysse B, Enjalbert L. Malignant external otitis and polymorphonuclear leukocyte migration impairment. Improvement with ascorbic acid. Arch Otolaryngol. 1982;108:122.
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