Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.4
USERS' SCORE
Good
Based on 2 Reviews
8.3
Supplement Facts
Serving Size: Two (2) softgels
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%**
Total Carbohydrate
<1 g
<1%**
Vitamin C (as ascorbic acid)
120 mg
133%
Pacran® Whole Fruit Cranberry (Vaccinium macrocarpon)
500 mg
†
Top Medical Research Studies
9
Vitamin C reduces cholesterol levels
We explored how vitamin C supplementation affects cholesterol levels in broiler chickens, particularly under heat stress conditions. Through a thorough meta-analysis of 35 studies conducted between 1985 and 2023, we assessed various performance metrics, including blood parameters, carcass characteristics, and overall meat quality.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
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8
Cranberry extract aids cholesterol management
We evaluated the effects of cranberry extract on high cholesterol levels in rats that were made obese through a high-fat diet. Male Wistar rats were divided into two main groups: one group received a standard diet, while the other was fed a high-fat diet. After a certain period, the rats in each group were further split to receive either cranberry extract or water for a month.
Our findings indicated that the high-fat diet led to increased body weight, high levels of cholesterol and triglycerides, and signs of liver damage. Interestingly, the group that received cranberry extract showed a reduction in cholesterol and triglyceride levels compared to those that did not receive the extract. Although the cranberry extract did not completely reverse obesity, it significantly improved the metabolic health of the rats, suggesting potential benefits for managing high cholesterol in obesity-related conditions.
This study highlights the promising role of cranberry extract as a natural intervention for improving cholesterol levels, although more research is needed to confirm its effects in humans.
Our findings indicated that the high-fat diet led to increased body weight, high levels of cholesterol and triglycerides, and signs of liver damage. Interestingly, the group that received cranberry extract showed a reduction in cholesterol and triglyceride levels compared to those that did not receive the extract. Although the cranberry extract did not completely reverse obesity, it significantly improved the metabolic health of the rats, suggesting potential benefits for managing high cholesterol in obesity-related conditions.
This study highlights the promising role of cranberry extract as a natural intervention for improving cholesterol levels, although more research is needed to confirm its effects in humans.
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8
We explored the potential benefits of cranberry juice, specifically from the vaccinium macrocarpon berry, on cholesterol levels and vascular health. To investigate this, we conducted a study with ovariectomized rats, an animal model that mimics certain aspects of postmenopausal women, who are at increased risk for heart disease due to hormonal changes.
Over eight weeks, these rats received a daily dose of cranberry juice, equivalent to what's been used in recent human clinical studies. Our measurements focused on cholesterol levels in their serum and the vascular responses of their aorta.
We observed favorable changes in both cholesterol profiles and endothelial function, which is crucial for maintaining healthy blood vessels. This suggests that incorporating cranberry juice into one’s diet could be a simple yet effective strategy for improving cardiovascular health, especially for those experiencing estrogen deficiency.
Overall, our findings present exciting possibilities for developing cranberry products as dietary supplements tailored for postmenopausal women, contributing positively to their heart health.
Over eight weeks, these rats received a daily dose of cranberry juice, equivalent to what's been used in recent human clinical studies. Our measurements focused on cholesterol levels in their serum and the vascular responses of their aorta.
We observed favorable changes in both cholesterol profiles and endothelial function, which is crucial for maintaining healthy blood vessels. This suggests that incorporating cranberry juice into one’s diet could be a simple yet effective strategy for improving cardiovascular health, especially for those experiencing estrogen deficiency.
Overall, our findings present exciting possibilities for developing cranberry products as dietary supplements tailored for postmenopausal women, contributing positively to their heart health.
Read More
Most Useful Reviews
7.5
Reduced uric acid
1 people found this helpful
I purchased this for my husband when he had high levels of uric acid, and he mentioned it helped lower his uric acid levels.
Read More
7.5
Highly recommended pills
These effective pills have provided pleasing results. The softgels are easy to swallow. I highly recommend them for anyone needing to manage their high cholesterol.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.4
- All Researches
9
Vitamin C reduces cholesterol levels
We explored how vitamin C supplementation affects cholesterol levels in broiler chickens, particularly under heat stress conditions. Through a thorough meta-analysis of 35 studies conducted between 1985 and 2023, we assessed various performance metrics, including blood parameters, carcass characteristics, and overall meat quality.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Read More
9
We conducted a study to explore how vitamin C, combined with chromium, affects high cholesterol levels in patients with type 2 diabetes. This interesting research involved 60 participants, evenly split between a treatment group receiving vitamin C (500mg) and chromium (200µg), and a control group taking a placebo.
Our analysis revealed notable reductions in several important lipid measurements within the treatment group. Specifically, we observed a significant drop in total cholesterol and improvements in High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL), and triglyceride levels.
The results illuminate the potential benefits of vitamin C and chromium in managing cholesterol levels for those impacted by type 2 diabetes. While this study doesn't focus solely on vitamin C, the combined effects of both supplements indicate a promising avenue for improving lipid profiles and overall health in diabetic patients.
Our analysis revealed notable reductions in several important lipid measurements within the treatment group. Specifically, we observed a significant drop in total cholesterol and improvements in High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL), and triglyceride levels.
The results illuminate the potential benefits of vitamin C and chromium in managing cholesterol levels for those impacted by type 2 diabetes. While this study doesn't focus solely on vitamin C, the combined effects of both supplements indicate a promising avenue for improving lipid profiles and overall health in diabetic patients.
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9
To explore the impact of vitamin C on high cholesterol levels, we designed a study involving 106 young male athletes. They were divided into five groups, including those who did not exercise and those who underwent high-intensity interval training (HIIT), some with added vitamin C, vitamin E, or both. Over eight weeks, we assessed changes in lipid profiles and various blood variables.
Our findings were promising for those taking vitamins C and E alongside regular exercise. Participants who supplemented with these vitamins and engaged in HIIT showed significant drops in body weight, overall fat percentage, total cholesterol, and triglycerides. Remarkably, levels of high-density lipoprotein cholesterol, often dubbed "good cholesterol," increased in all four intervention groups. This suggests a potential role for vitamin C in improving cholesterol levels, especially when paired with an active lifestyle.
However, we also noted some adverse changes—specifically, reductions in certain blood cell counts among those only doing HIIT. While the vitamin-supplemented groups did experience effective elevation in beneficial vitamin levels, the overall effects of vitamin C alone on high cholesterol were less definitive, as the benefits appeared more in combination with exercise. It's safe to say that although vitamin C shows some promise in reducing cholesterol, the strongest benefits occur when it's part of a broader healthy regimen.
Our findings were promising for those taking vitamins C and E alongside regular exercise. Participants who supplemented with these vitamins and engaged in HIIT showed significant drops in body weight, overall fat percentage, total cholesterol, and triglycerides. Remarkably, levels of high-density lipoprotein cholesterol, often dubbed "good cholesterol," increased in all four intervention groups. This suggests a potential role for vitamin C in improving cholesterol levels, especially when paired with an active lifestyle.
However, we also noted some adverse changes—specifically, reductions in certain blood cell counts among those only doing HIIT. While the vitamin-supplemented groups did experience effective elevation in beneficial vitamin levels, the overall effects of vitamin C alone on high cholesterol were less definitive, as the benefits appeared more in combination with exercise. It's safe to say that although vitamin C shows some promise in reducing cholesterol, the strongest benefits occur when it's part of a broader healthy regimen.
Read More
8
Cranberry beverage improves cholesterol
In a recent study, we explored the effects of a low calorie, high polyphenol cranberry beverage on health markers associated with high cholesterol and inflammation. Conducted with 78 overweight individuals, the research employed a randomized, double-blind, placebo-controlled design over eight weeks. Participants consumed either the cranberry extract beverage or a placebo, allowing us to carefully evaluate the impact of the cranberry drink on various health parameters.
At the end of the trial, we observed interesting changes in the participants' health. Notably, the participants who consumed the cranberry beverage showed improvements in blood sugar regulation and reduced levels of inflammation markers. Additionally, there was a rise in HDL cholesterol, which is often referred to as the "good" cholesterol because it helps reduce the risk of heart disease.
Although the study didn't isolate the specific effects of vaccinium macrocarpon on cholesterol per se, the results suggest that the high polyphenol content in cranberry could play a beneficial role in managing cardiovascular risk factors. Overall, this could be a promising addition to a diet aimed at improving cholesterol levels and overall heart health.
At the end of the trial, we observed interesting changes in the participants' health. Notably, the participants who consumed the cranberry beverage showed improvements in blood sugar regulation and reduced levels of inflammation markers. Additionally, there was a rise in HDL cholesterol, which is often referred to as the "good" cholesterol because it helps reduce the risk of heart disease.
Although the study didn't isolate the specific effects of vaccinium macrocarpon on cholesterol per se, the results suggest that the high polyphenol content in cranberry could play a beneficial role in managing cardiovascular risk factors. Overall, this could be a promising addition to a diet aimed at improving cholesterol levels and overall heart health.
Read More
8
We explored how cranberry anthocyanins, the natural pigments found in cranberries, could help manage high cholesterol levels. In our study, we tested this by feeding hamsters a high-cholesterol diet alongside different amounts of cranberry extract. The hamsters were divided into five groups: one group received a standard diet, while others had varying levels of cranberry extract or a well-known cholesterol-lowering drug.
Over six weeks, we measured the levels of cholesterol in their blood and tracked how much cholesterol was excreted in their feces. Our goal was to see if cranberry anthocyanins could lower cholesterol by increasing how much cholesterol was expelled from the body.
The results showed that cranberry anthocyanins did indeed help improve the cholesterol profiles of the hamsters on a high-cholesterol diet. They enhanced the excretion of cholesterol, which is a promising finding for natural remedies. However, it appears that this effect may not be linked to changes in the genes responsible for cholesterol absorption and metabolism.
Overall, our findings suggest that incorporating cranberry extract could be a simple and effective way to help manage cholesterol levels, although more research is needed to fully understand the mechanisms at work.
Over six weeks, we measured the levels of cholesterol in their blood and tracked how much cholesterol was excreted in their feces. Our goal was to see if cranberry anthocyanins could lower cholesterol by increasing how much cholesterol was expelled from the body.
The results showed that cranberry anthocyanins did indeed help improve the cholesterol profiles of the hamsters on a high-cholesterol diet. They enhanced the excretion of cholesterol, which is a promising finding for natural remedies. However, it appears that this effect may not be linked to changes in the genes responsible for cholesterol absorption and metabolism.
Overall, our findings suggest that incorporating cranberry extract could be a simple and effective way to help manage cholesterol levels, although more research is needed to fully understand the mechanisms at work.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Reduced uric acid
1 people found this helpful
I purchased this for my husband when he had high levels of uric acid, and he mentioned it helped lower his uric acid levels.
Read More
7.5
Highly recommended pills
These effective pills have provided pleasing results. The softgels are easy to swallow. I highly recommend them for anyone needing to manage their high cholesterol.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Tavakolinasab F, Hashemi M. Effect of Using Vitamin C Supplementation on Performance, Blood Parameters, Carcass Characteristics and Meat Quality of Broiler Chickens Under Heat Stress Condition: A Meta-Analysis. J Anim Physiol Anim Nutr (Berl). 2025. 10.1111/jpn.14091
- Sabar N, Hussain MI, Saleem H, Khan MA, Khalid H, et al. Synchronizing positive effect of vitamin C and chromium on hyper lipidemia, hyperglycemia, liver enzymes and BMI of diabetes mellitus type 2 patients. Pak J Pharm Sci. 2024;37:199.
- Son J, Lee WD, Kim H, Hong EC, Kim HJ, et al. A comparative study on feeding timing and additive types of broilers in a high-temperature environment. J Anim Sci. 2023;101. 10.1093/jas/skad290
- Sarkar S, Dey SK, Datta G, Bandyopadhyay A. Vitamin C and E supplementation and high intensity interval training induced changes in lipid profile and haematological variables of young males. Sports Med Health Sci. 2023;5:137. 10.1016/j.smhs.2023.03.006
- Darand M, Salehi-Abargouei A, Vahidi Mehrjardi MY, Feizi A, Seyedhossaini SM, et al. Joint effects of paraoxonase 1 rs662 polymorphism and vitamins C/E intake on coronary artery disease severity (Gensini and SYNTAX scores) and lipid profile in patients undergoing coronary angiography. Front Nutr. 2022;9:1097411. 10.3389/fnut.2022.1097411
- Omidi S, Bouyeh M, Seidavi A. The effect of vitamin C and aspirin supplementation on the performance of turkeys under normal conditions. Anim Biotechnol. 2023;34:3395. 10.1080/10495398.2022.2152037
- Li X, Chen W, Xia J, Pan D, Sun G. The Effects of Cranberry Consumption on Glycemic and Lipid Profiles in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients. 2024;16. 10.3390/nu16060782
- Caceres C, Kim MB, Bae M, Pham TX, Lee Y, et al. The effect of cranberry consumption on lipid metabolism and inflammation in human apo A-I transgenic mice fed a high-fat and high-cholesterol diet. Br J Nutr. 2021;126:183. 10.1017/S0007114520004080
- Chew B, Mathison B, Kimble L, McKay D, Kaspar K, et al. Chronic consumption of a low calorie, high polyphenol cranberry beverage attenuates inflammation and improves glucoregulation and HDL cholesterol in healthy overweight humans: a randomized controlled trial. Eur J Nutr. 2019;58:1223. 10.1007/s00394-018-1643-z
- Wang L, Zhu H, Zhao Y, Jiao R, Lei L, et al. Cranberry anthocyanin as an herbal medicine lowers plasma cholesterol by increasing excretion of fecal sterols. Phytomedicine. 2018;38:98. 10.1016/j.phymed.2017.11.008
- Peixoto TC, Moura EG, de Oliveira E, Soares PN, Guarda DS, et al. Cranberry (Vaccinium macrocarpon) extract treatment improves triglyceridemia, liver cholesterol, liver steatosis, oxidative damage and corticosteronemia in rats rendered obese by high fat diet. Eur J Nutr. 2018;57:1829. 10.1007/s00394-017-1467-2
- Novotny JA, Baer DJ, Khoo C, Gebauer SK, Charron CS. Cranberry juice consumption lowers markers of cardiometabolic risk, including blood pressure and circulating C-reactive protein, triglyceride, and glucose concentrations in adults. J Nutr. 2015;145:1185. 10.3945/jn.114.203190
- Yung LM, Tian XY, Wong WT, Leung FP, Yung LH, et al. Chronic cranberry juice consumption restores cholesterol profiles and improves endothelial function in ovariectomized rats. Eur J Nutr. 2013;52:1145. 10.1007/s00394-012-0425-2
- Lee IT, Chan YC, Lin CW, Lee WJ, Sheu WH. Effect of cranberry extracts on lipid profiles in subjects with Type 2 diabetes. Diabet Med. 2008;25:1473. 10.1111/j.1464-5491.2008.02588.x
