Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.3
USERS' SCORE
Good
Based on 4 Reviews
8.4
Supplement Facts
Serving Size: One (1) Capsule
Amount Per Serving
%DV
Calories
0
Total Carbohydrate
0 g
0%+
Total Sugars
0 g
**
Incl. 0 g Added Sugars
0%+
Lactobacillus rhamnosus GG
83 mg (20 billion CFUs)
**
Inulin (Chicory root extract)
200 mg
**
Top Medical Research Studies
8
We examined the effects of Lactobacillus rhamnosus HN001 on eczema prevention among children with genetic predispositions. In our double-blind, randomized, placebo-controlled study involving 331 children, we discovered that those with specific high-risk gene variants experienced lower eczema rates when treated with HN001, compared to those receiving a placebo. This suggests Lactobacillus rhamnosus might be particularly beneficial for children at greater genetic risk of eczema and may even influence the severity of eczema and related allergic conditions.
Read More
2
We investigated whether taking the probiotic Lactobacillus rhamnosus GG during pregnancy could help lower the risk of eczema in infants. In a randomized controlled trial, 250 pregnant women, whose babies were at high risk for allergic diseases, took this probiotic from 36 weeks until delivery.
Unfortunately, we found that this prenatal treatment didn’t significantly reduce the incidence of eczema or any allergic reactions in their babies. This suggests that probiotics might need to be given after birth, or we may need to explore different strains for better results.
Unfortunately, we found that this prenatal treatment didn’t significantly reduce the incidence of eczema or any allergic reactions in their babies. This suggests that probiotics might need to be given after birth, or we may need to explore different strains for better results.
Read More
9
We explored the potential of Lactobacillus rhamnosus HN001 in reducing eczema among infants at high risk. Through a robust double-blind trial, expecting mothers took the probiotic from 35 weeks pregnant and continued while breastfeeding, while infants received it from birth to two years. Remarkably, this approach halved the prevalence of eczema by ages 2 and 4. Even better, the benefits seemed to last until age 6, showing promising potential in preventing eczema and associated allergic sensitization. However, another probiotic, HN019, did not show similar effects, suggesting specific benefits tied to HN001.
Read More
Most Useful Reviews
9
Cured my eczema
1 people found this helpful
The best probiotic! It has significantly helped me eliminate my chronic eczema.
Read More
9
Rebalances gut microbiome
This probiotic is outstanding; it has helped rebalance my gut microbiome and aids in managing eczema. Highly recommended!
Read More
7.5
Controls eczema
1 people found this helpful
Close to the original probiotics of the human body, it can effectively manage eczema.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.3
- All Researches
9.5
We conducted a study to see if giving probiotics to mothers during pregnancy and breastfeeding could help reduce eczema in infants at risk. This double-blind, placebo-controlled trial involved 241 mother-infant pairs, where mothers were given either specific probiotics or a placebo.
Our findings showed that infants whose mothers took Lactobacillus rhamnosus and Bifidobacterium longum had a significantly lower risk of developing eczema in their first two years. This suggests that probiotics can be a safe and effective preventive measure for high-risk infants.
Our findings showed that infants whose mothers took Lactobacillus rhamnosus and Bifidobacterium longum had a significantly lower risk of developing eczema in their first two years. This suggests that probiotics can be a safe and effective preventive measure for high-risk infants.
Read More
9
We explored the potential of Lactobacillus rhamnosus HN001 in reducing eczema among infants at high risk. Through a robust double-blind trial, expecting mothers took the probiotic from 35 weeks pregnant and continued while breastfeeding, while infants received it from birth to two years. Remarkably, this approach halved the prevalence of eczema by ages 2 and 4. Even better, the benefits seemed to last until age 6, showing promising potential in preventing eczema and associated allergic sensitization. However, another probiotic, HN019, did not show similar effects, suggesting specific benefits tied to HN001.
Read More
9
Lactobacillus rhamnosus reduces eczema prevalence
We conducted a robust study using a double-blind randomized placebo-controlled trial to explore the impact of Lactobacillus rhamnosus HN001 on eczema in young children.
Mothers supplemented with HN001 from the 35th week of pregnancy until 6 months of breastfeeding, while infants continued taking the probiotic until age 2.
Remarkably, we found that this approach halved the prevalence of eczema by age 2, and its protective effects persisted up to age 4. HN001 may be a promising preventive measure for infants at high risk of allergic diseases.
Mothers supplemented with HN001 from the 35th week of pregnancy until 6 months of breastfeeding, while infants continued taking the probiotic until age 2.
Remarkably, we found that this approach halved the prevalence of eczema by age 2, and its protective effects persisted up to age 4. HN001 may be a promising preventive measure for infants at high risk of allergic diseases.
Read More
8
Probiotic formula benefits allergy management
We examined the impact of several infant formulas on allergies in children with cow's milk allergy over 36 months.
Our findings showed that the extensively hydrolyzed casein formula containing Lactobacillus rhamnosus GG led to a significantly lower rate of eczema and other allergic issues compared to other formula types.
Children treated with this particular formula also exhibited a faster development of immune tolerance.
It appears that incorporating this probiotic could be beneficial for managing allergies in infants.
Our findings showed that the extensively hydrolyzed casein formula containing Lactobacillus rhamnosus GG led to a significantly lower rate of eczema and other allergic issues compared to other formula types.
Children treated with this particular formula also exhibited a faster development of immune tolerance.
It appears that incorporating this probiotic could be beneficial for managing allergies in infants.
Read More
8
In a double-blind, placebo-controlled trial, we evaluated the effect of Lactobacillus rhamnosus alongside Bifidobacterium on eczema development in infants.
Over 290 participants received either the probiotic mixture or a placebo. Notably, at the end of the six-month intervention, only 4.2% of the probiotic group developed eczema, compared to 11.5% in the placebo group.
Other allergic conditions like asthma and rhinitis showed no significant differences, indicating that while probiotics may help with eczema, they don’t necessarily prevent other common allergies.
Over 290 participants received either the probiotic mixture or a placebo. Notably, at the end of the six-month intervention, only 4.2% of the probiotic group developed eczema, compared to 11.5% in the placebo group.
Other allergic conditions like asthma and rhinitis showed no significant differences, indicating that while probiotics may help with eczema, they don’t necessarily prevent other common allergies.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Cured my eczema
1 people found this helpful
The best probiotic! It has significantly helped me eliminate my chronic eczema.
Read More
9
Rebalances gut microbiome
This probiotic is outstanding; it has helped rebalance my gut microbiome and aids in managing eczema. Highly recommended!
Read More
7.5
Controls eczema
1 people found this helpful
Close to the original probiotics of the human body, it can effectively manage eczema.
Read More
7.5
Improves children's eczema
Culturelle Ultimate Strength Probiotic is beneficial for children with eczema; my kids have shown visible improvements.
Read More
Frequently Asked Questions
9
Cured my eczema
1 people found this helpful
The best probiotic! It has significantly helped me eliminate my chronic eczema.
9
Rebalances gut microbiome
This probiotic is outstanding; it has helped rebalance my gut microbiome and aids in managing eczema. Highly recommended!
7.5
Improves children's eczema
Culturelle Ultimate Strength Probiotic is beneficial for children with eczema; my kids have shown visible improvements.
7.5
Controls eczema
1 people found this helpful
Close to the original probiotics of the human body, it can effectively manage eczema.
9
We explored the potential of Lactobacillus rhamnosus HN001 in reducing eczema among infants at high risk. Through a robust double-blind trial, expecting mothers took the probiotic from 35 weeks pregnant and continued while breastfeeding, while infants received it from birth to two years. Remarkably, this approach halved the prevalence of eczema by ages 2 and 4. Even better, the benefits seemed to last until age 6, showing promising potential in preventing eczema and associated allergic sensitization. However, another probiotic, HN019, did not show similar effects, suggesting specific benefits tied to HN001.
8
This study looked into how two probiotics, Lactobacillus rhamnosus HN001 and Bifidobacterium animalis HN019, could affect the risk of eczema in genetically predisposed infants. Using a double-blind, randomized, placebo-controlled trial with 331 participants, we found that HN001 significantly reduced eczema risks linked to genetic variations, while HN019 had minimal impact.
Our results indicate that HN001 is particularly effective, addressing multiple genetic factors that contribute to eczema development. This opens new avenues for preventive strategies in at-risk populations.
Our results indicate that HN001 is particularly effective, addressing multiple genetic factors that contribute to eczema development. This opens new avenues for preventive strategies in at-risk populations.
2
We conducted a randomized placebo-controlled trial to evaluate whether maternal supplementation with the probiotic Lactobacillus rhamnosus HN001 could reduce the risk of infant eczema. Mothers took the probiotic from 14 to 16 weeks of pregnancy until 6 months after birth while breastfeeding, but the infants didn’t receive the probiotic directly.
Unfortunately, our findings showed that this approach did not significantly reduce eczema or related conditions by the time the children reached 12 months old. This contrasts with previous research where both mothers and infants took the supplement and saw better results.
Unfortunately, our findings showed that this approach did not significantly reduce eczema or related conditions by the time the children reached 12 months old. This contrasts with previous research where both mothers and infants took the supplement and saw better results.
8
Eczema prevention linked to probiotics
We explored the effectiveness of probiotics, particularly Lactobacillus rhamnosus, in preventing eczema and food allergies. The research highlights that combining prenatal and postnatal probiotic treatment can significantly reduce eczema prevalence in infants up to 2 years old, with some benefits lasting until age 4. However, not all studies are consistent—while many show promising results, others do not find any significant effects. This suggests that the timing and specific strain of probiotics play a crucial role in their potential benefits.
9
Lactobacillus rhamnosus reduces eczema prevalence
We conducted a robust study using a double-blind randomized placebo-controlled trial to explore the impact of Lactobacillus rhamnosus HN001 on eczema in young children.
Mothers supplemented with HN001 from the 35th week of pregnancy until 6 months of breastfeeding, while infants continued taking the probiotic until age 2.
Remarkably, we found that this approach halved the prevalence of eczema by age 2, and its protective effects persisted up to age 4. HN001 may be a promising preventive measure for infants at high risk of allergic diseases.
Mothers supplemented with HN001 from the 35th week of pregnancy until 6 months of breastfeeding, while infants continued taking the probiotic until age 2.
Remarkably, we found that this approach halved the prevalence of eczema by age 2, and its protective effects persisted up to age 4. HN001 may be a promising preventive measure for infants at high risk of allergic diseases.
References
- Voigt J, Lele M. Lactobacillus rhamnosus Used in the Perinatal Period for the Prevention of Atopic Dermatitis in Infants: A Systematic Review and Meta-Analysis of Randomized Trials. Am J Clin Dermatol. 2022;23:801. doi:10.1007/s40257-022-00723-x
- Nocerino R, Bedogni G, Carucci L, Cosenza L, Cozzolino T, et al. The Impact of Formula Choice for the Management of Pediatric Cow's Milk Allergy on the Occurrence of Other Allergic Manifestations: The Atopic March Cohort Study. J Pediatr. 2021;232:183. doi:10.1016/j.jpeds.2021.01.059
- Schmidt RM, Pilmann Laursen R, Bruun S, Larnkjaer A, Mølgaard C, et al. Probiotics in late infancy reduce the incidence of eczema: A randomized controlled trial. Pediatr Allergy Immunol. 2019;30:335. doi:10.1111/pai.13018
- Murphy R, Morgan XC, Wang XY, Wickens K, Purdie G, et al. Eczema-protective probiotic alters infant gut microbiome functional capacity but not composition: sub-sample analysis from a RCT. Benef Microbes. 2019;10:5. doi:10.3920/BM2017.0191
- Wickens K, Barthow C, Mitchell EA, Kang J, van Zyl N, et al. Effects of Lactobacillus rhamnosus HN001 in early life on the cumulative prevalence of allergic disease to 11 years. Pediatr Allergy Immunol. 2018;29:808. doi:10.1111/pai.12982
- Gulliver WP, Hutton AS, Ship N. Investigating the therapeutic potential of a probiotic in a clinical population with chronic hand dermatitis. Clin Cosmet Investig Dermatol. 2018;11:265. doi:10.2147/CCID.S164748
- Wickens K, Barthow C, Mitchell EA, Stanley TV, Purdie G, et al. Maternal supplementation alone with Lactobacillus rhamnosus HN001 during pregnancy and breastfeeding does not reduce infant eczema. Pediatr Allergy Immunol. 2018;29:296. doi:10.1111/pai.12874
- Berni Canani R, Di Costanzo M, Bedogni G, Amoroso A, Cosenza L, et al. Extensively hydrolyzed casein formula containing Lactobacillus rhamnosus GG reduces the occurrence of other allergic manifestations in children with cow's milk allergy: 3-year randomized controlled trial. J Allergy Clin Immunol. 2017;139:1906. doi:10.1016/j.jaci.2016.10.050
- Marlow G, Han DY, Wickens K, Stanley T, Crane J, et al. Differential effects of two probiotics on the risks of eczema and atopy associated with single nucleotide polymorphisms to Toll-like receptors. Pediatr Allergy Immunol. 2015;26:262. doi:10.1111/pai.12371
- Ismail IH, Boyle RJ, Mah LJ, Licciardi PV, Tang ML. Reduced neonatal regulatory T cell response to microbial stimuli associates with subsequent eczema in high-risk infants. Pediatr Allergy Immunol. 2014;25:674. doi:10.1111/pai.12303
- Morgan AR, Han DY, Wickens K, Barthow C, Mitchell EA, et al. Differential modification of genetic susceptibility to childhood eczema by two probiotics. Clin Exp Allergy. 2014;44:1255. doi:10.1111/cea.12394
- Wickens K, Stanley TV, Mitchell EA, Barthow C, Fitzharris P, et al. Early supplementation with Lactobacillus rhamnosus HN001 reduces eczema prevalence to 6 years: does it also reduce atopic sensitization?. Clin Exp Allergy. 2013;43:1048. doi:10.1111/cea.12154
- Kuitunen M. Probiotics and prebiotics in preventing food allergy and eczema. Curr Opin Allergy Clin Immunol. 2013;13:280. doi:10.1097/ACI.0b013e328360ed66
- Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130:1355. doi:10.1016/j.jaci.2012.09.003
- Wickens K, Black P, Stanley TV, Mitchell E, Barthow C, et al. A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years. Clin Exp Allergy. 2012;42:1071. doi:10.1111/j.1365-2222.2012.03975.x
- Boyle RJ, Ismail IH, Kivivuori S, Licciardi PV, Robins-Browne RM, et al. Lactobacillus GG treatment during pregnancy for the prevention of eczema: a randomized controlled trial. Allergy. 2011;66:509. doi:10.1111/j.1398-9995.2010.02507.x
