Induces Two Types of Dendritic Cell Activation and Effectively Suppresses Onset of the Common Cold: A Randomized, Double-Blind, Placebo-Controlled Trial.
We looked into how GCL1815, a type of lactic acid bacterium, might aid in preventing the common cold. In our randomized, double-blind study with 200 participants, we found that those who took GCL1815 capsules for eight weeks had significantly lower symptoms of colds, like fatigue and nasal congestion, compared to those on placebo. We also observed key immune responses related to dendritic cell activation that were notably more enhanced in participants taking GCL1815. This suggests that GCL1815 is promising in boosting the body’s defenses against the cold.
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5
Lactobacillus impact on immunity
Supplementation with heat-sterilized Lactobacillus crispatus strain KT-11 stimulates the T cell-related immune function of healthy Japanese adults: A pilot randomized, placebo-controlled, double-blind, parallel-group study.
We conducted a pilot study to explore the effects of heat-sterilized Lactobacillus crispatus strain KT-11 on immune function in healthy adults. Over four weeks, 22 participants took either KT-11 or a placebo. We observed that those taking KT-11 had higher counts of certain immune cells and reported fewer cold-like symptoms, particularly fatigue. However, there were no significant increases in antibodies related to SARS-CoV-2. This indicates potential benefits of KT-11 for immune activity, suggesting further studies on its effectiveness are warranted.
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Most Useful Reviews
10
No cold symptoms
1 people found this helpful
This probiotic truly works. I took it while on antibiotics without experiencing dysbiosis, and my body functions well. I haven't noticed any side effects, and remarkably, I did not suffer from seasonal colds this year! Is that a coincidence? I prefer to believe it strengthened my immune system.
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9
Immune strengthener
Culturelle is a fantastic probiotic that I purchase for my family during the winter to strengthen their immune system. Everyone was coming down with illness, so I ensure they all take probiotics to fend off colds and flu. These are reliable probiotics that I buy when on sale.
Read More
8
Early cold relief
Excellent! I liked the probiotic. It worked well for me and my husband. I take it at the first signs of a cold.
Induces Two Types of Dendritic Cell Activation and Effectively Suppresses Onset of the Common Cold: A Randomized, Double-Blind, Placebo-Controlled Trial.
We looked into how GCL1815, a type of lactic acid bacterium, might aid in preventing the common cold. In our randomized, double-blind study with 200 participants, we found that those who took GCL1815 capsules for eight weeks had significantly lower symptoms of colds, like fatigue and nasal congestion, compared to those on placebo. We also observed key immune responses related to dendritic cell activation that were notably more enhanced in participants taking GCL1815. This suggests that GCL1815 is promising in boosting the body’s defenses against the cold.
Read More
5
Lactobacillus impact on immunity
Supplementation with heat-sterilized Lactobacillus crispatus strain KT-11 stimulates the T cell-related immune function of healthy Japanese adults: A pilot randomized, placebo-controlled, double-blind, parallel-group study.
We conducted a pilot study to explore the effects of heat-sterilized Lactobacillus crispatus strain KT-11 on immune function in healthy adults. Over four weeks, 22 participants took either KT-11 or a placebo. We observed that those taking KT-11 had higher counts of certain immune cells and reported fewer cold-like symptoms, particularly fatigue. However, there were no significant increases in antibodies related to SARS-CoV-2. This indicates potential benefits of KT-11 for immune activity, suggesting further studies on its effectiveness are warranted.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.2
All Reviews
Positive Reviews
Negative Reviews
10
No cold symptoms
1 people found this helpful
This probiotic truly works. I took it while on antibiotics without experiencing dysbiosis, and my body functions well. I haven't noticed any side effects, and remarkably, I did not suffer from seasonal colds this year! Is that a coincidence? I prefer to believe it strengthened my immune system.
Read More
9
Immune strengthener
Culturelle is a fantastic probiotic that I purchase for my family during the winter to strengthen their immune system. Everyone was coming down with illness, so I ensure they all take probiotics to fend off colds and flu. These are reliable probiotics that I buy when on sale.
Read More
8
Early cold relief
Excellent! I liked the probiotic. It worked well for me and my husband. I take it at the first signs of a cold.
Read More
7
Speeds cold recovery
I recommend these probiotics during a cold, as the strains included in the composition contribute to a faster recovery.
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6
Reduced cold frequency
I took these probiotics in winter during cold seasons to boost immunity, and I found I got sick less often.
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References
Watanabe I, Suzuki N, Takara T. Supplementation with heat-sterilized Lactobacillus crispatus strain KT-11 stimulates the T cell-related immune function of healthy Japanese adults: A pilot randomized, placebo-controlled, double-blind, parallel-group study. Nutr Res. 2025;134:99. 10.1016/j.nutres.2024.12.004
Wada H, Mawatari T, Saito Y, Azuma N, Iwama Y. Induces Two Types of Dendritic Cell Activation and Effectively Suppresses Onset of the Common Cold: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2024;17. 10.3390/nu17010101