Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 45 Researches
7.3
USERS' SCORE
Good
Based on 22 Reviews
8
Supplement Facts
Serving Size: One (1) Capsule
Amount Per Serving
%DV
Calories
0
Total Carbohydrate
0 g
0%+
Total Sugars
0 g
**
Incl. 0 g Added Sugars
0%+
Lactobacillus rhamnosus GG
40 mg (10 billion CFUs)
**
Inulin (Chicory Root Extract)
200 mg
**
Top Medical Research Studies
9.5
We assessed the effectiveness of a probiotic blend of two Lactobacillus strains in treating diarrhea-predominant irritable bowel syndrome (IBS-D) through a randomized, single-blinded trial. Involving 100 patients, one group received standard IBS treatment while the other added probiotics.
After 12 weeks, both groups experienced symptom relief, but the probiotic group showed a greater decrease in their IBS symptoms. Remarkably, all patients on probiotics either found complete symptom relief or had mild symptoms, compared to over 14% of those on standard treatment who still experienced moderate IBS.
After 12 weeks, both groups experienced symptom relief, but the probiotic group showed a greater decrease in their IBS symptoms. Remarkably, all patients on probiotics either found complete symptom relief or had mild symptoms, compared to over 14% of those on standard treatment who still experienced moderate IBS.
Read More
9
We aimed to understand how Lacticaseibacillus rhamnosus IDCC 3201 (RH 3201) affects irritable bowel syndrome with constipation (IBS-C) through a thorough study. In a randomized, double-blind trial, 30 participants took either RH 3201 or a placebo for 8 weeks.
Those taking RH 3201 experienced significant improvements, including fewer bowel discomforts and reduced bloating issues. We also observed an increase in certain beneficial gut bacteria and a link between specific metabolites and symptom relief. Overall, RH 3201 shows promise as an effective treatment for IBS-C.
Those taking RH 3201 experienced significant improvements, including fewer bowel discomforts and reduced bloating issues. We also observed an increase in certain beneficial gut bacteria and a link between specific metabolites and symptom relief. Overall, RH 3201 shows promise as an effective treatment for IBS-C.
Read More
We evaluated how the probiotic Neobiotic Lactobalance® can help patients with irritable bowel syndrome (IBS) experiencing diarrhea and those suffering from antibiotic-associated diarrhea (AAD). Over a 21-day period, 54 participants took one capsule daily.
The results were promising, as symptoms like abdominal pain and diarrheal disorders significantly improved. Patients experienced a notable drop in symptom severity, and beneficial changes in gut bacteria were also observed.
Overall, Lactobalance® appears to support a healthier gut microbiome and alleviate symptoms for these patients.
The results were promising, as symptoms like abdominal pain and diarrheal disorders significantly improved. Patients experienced a notable drop in symptom severity, and beneficial changes in gut bacteria were also observed.
Overall, Lactobalance® appears to support a healthier gut microbiome and alleviate symptoms for these patients.
Read More
Most Useful Reviews
9
Pain relief
2 people found this helpful
A lifesaver! I've endured gut-related issues for years. After three months of taking Culturelle, my painful bloating has significantly reduced. Even during a vacation with an unfamiliar diet, I took it daily and experienced no stomach problems, achieving regular bowel movements.
Read More
9
Improved regularity
1 people found this helpful
I've noticed significant improvement in my bowel regularity. This probiotic has effectively addressed my occasional constipation, helping me feel more balanced and in control of my digestive health.
Read More
7.5
Reduced GERD symptoms
1 people found this helpful
This probiotic is good, though a bit pricey. I take it before breakfast, and it has reduced my GERD symptoms. Initially, I had a rumbling stomach for a week, but that has passed. My bowel movements are now regular, and I feel better overall.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 45 Researches
7.3
- All Researches
9.5
Our evaluation focused on the effectiveness of combining probiotics with trimebutine for treating irritable bowel syndrome (IBS). Through a systematic review of 37 randomized controlled trials involving 4,360 participants, we found that this combination therapy significantly outperformed trimebutine alone.
The effective rate was an impressive 93.5% for those receiving both treatments compared to just 73.8% for trimebutine alone. Notably, while side effects were mild in both groups, the combination therapy displayed a favorable safety profile. This suggests that using specific probiotic strains can enhance the treatment outcome for individuals with IBS.
The effective rate was an impressive 93.5% for those receiving both treatments compared to just 73.8% for trimebutine alone. Notably, while side effects were mild in both groups, the combination therapy displayed a favorable safety profile. This suggests that using specific probiotic strains can enhance the treatment outcome for individuals with IBS.
Read More
9.5
We assessed the effectiveness of a probiotic blend of two Lactobacillus strains in treating diarrhea-predominant irritable bowel syndrome (IBS-D) through a randomized, single-blinded trial. Involving 100 patients, one group received standard IBS treatment while the other added probiotics.
After 12 weeks, both groups experienced symptom relief, but the probiotic group showed a greater decrease in their IBS symptoms. Remarkably, all patients on probiotics either found complete symptom relief or had mild symptoms, compared to over 14% of those on standard treatment who still experienced moderate IBS.
After 12 weeks, both groups experienced symptom relief, but the probiotic group showed a greater decrease in their IBS symptoms. Remarkably, all patients on probiotics either found complete symptom relief or had mild symptoms, compared to over 14% of those on standard treatment who still experienced moderate IBS.
Read More
9
Probiotics support intestinal health
We assessed how a multi-strain probiotic, Serobioma, affects gut health in individuals with Irritable Bowel Syndrome (IBS). This study involved IBS patients and healthy controls, looking at how Serobioma interacts with mucosal mediators from IBS patients' biopsies.
Remarkably, Serobioma improved the integrity of intestinal cell layers affected by IBS mediators, particularly in patients with diarrhea and mixed bowel habits. It successfully countered increased permeability, indicating its potential to support gut barrier function in IBS.
Remarkably, Serobioma improved the integrity of intestinal cell layers affected by IBS mediators, particularly in patients with diarrhea and mixed bowel habits. It successfully countered increased permeability, indicating its potential to support gut barrier function in IBS.
Read More
9
Synbiotic reduced IBS pain effectively
We explored the effects of a new synbiotic combination of chitin-glucan (CG) and NCFM in a rat model of irritable bowel syndrome (IBS).
After nine weeks, we found that both CG and NCFM reduced abdominal pain when used separately, but together, they significantly lessened visceral pain and intestinal inflammation.
Not only did this combination improve pain perception, but it also reduced colon lesions and inflammation markers. Overall, our findings suggest that this synbiotic approach holds promise for alleviating IBS symptoms.
After nine weeks, we found that both CG and NCFM reduced abdominal pain when used separately, but together, they significantly lessened visceral pain and intestinal inflammation.
Not only did this combination improve pain perception, but it also reduced colon lesions and inflammation markers. Overall, our findings suggest that this synbiotic approach holds promise for alleviating IBS symptoms.
Read More
We evaluated how the probiotic Neobiotic Lactobalance® can help patients with irritable bowel syndrome (IBS) experiencing diarrhea and those suffering from antibiotic-associated diarrhea (AAD). Over a 21-day period, 54 participants took one capsule daily.
The results were promising, as symptoms like abdominal pain and diarrheal disorders significantly improved. Patients experienced a notable drop in symptom severity, and beneficial changes in gut bacteria were also observed.
Overall, Lactobalance® appears to support a healthier gut microbiome and alleviate symptoms for these patients.
The results were promising, as symptoms like abdominal pain and diarrheal disorders significantly improved. Patients experienced a notable drop in symptom severity, and beneficial changes in gut bacteria were also observed.
Overall, Lactobalance® appears to support a healthier gut microbiome and alleviate symptoms for these patients.
Read More
User Reviews
USERS' SCORE
Good
Based on 22 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Pain relief
2 people found this helpful
A lifesaver! I've endured gut-related issues for years. After three months of taking Culturelle, my painful bloating has significantly reduced. Even during a vacation with an unfamiliar diet, I took it daily and experienced no stomach problems, achieving regular bowel movements.
Read More
9
Improved regularity
1 people found this helpful
I've noticed significant improvement in my bowel regularity. This probiotic has effectively addressed my occasional constipation, helping me feel more balanced and in control of my digestive health.
Read More
7.5
Reduced GERD symptoms
1 people found this helpful
This probiotic is good, though a bit pricey. I take it before breakfast, and it has reduced my GERD symptoms. Initially, I had a rumbling stomach for a week, but that has passed. My bowel movements are now regular, and I feel better overall.
Read More
9
Essential for IBS
Essential for managing my irritable bowel syndrome.
Read More
9
Restores function
Probiotics work remarkably well, instantly restoring my bowel function.
Read More
Frequently Asked Questions
7.5
Reduces bloating
Suffering from irritable bowel syndrome, I often felt gassy. After taking this, the effects were noticeable from day one, significantly reducing abdominal bloating.
8
Healthier stools
1 people found this helpful
After using this product for one box, my bowel movements have become much healthier. I used to experience diarrhoea easily, but now I have formed stools daily, and my bowel timings are more regular. The packaging is also safe and convenient.
9
Pain relief
2 people found this helpful
A lifesaver! I've endured gut-related issues for years. After three months of taking Culturelle, my painful bloating has significantly reduced. Even during a vacation with an unfamiliar diet, I took it daily and experienced no stomach problems, achieving regular bowel movements.
9
Improved regularity
1 people found this helpful
I've noticed significant improvement in my bowel regularity. This probiotic has effectively addressed my occasional constipation, helping me feel more balanced and in control of my digestive health.
7.5
Relieves constipation
This is a high-quality product that helps manage my digestion. It has assisted with constipation and occasional bloating, though I must remember to take it consistently.
9
Good for digestion
This probiotic by Culturelle offers 10 billion CFUs per capsule, with a pack containing 50 capsules for almost two months if taken daily. It really helps with my irritable bowel syndrome, as I've stopped experiencing diarrhoea. However, it is quite pricey compared to other brands.
7.5
Excellent for bloating
1 people found this helpful
I take these probiotics daily to combat bloating and improve gut health. Culturelle works wonderfully for me, aiding bowel movements and alleviating occasional bloating.
9
Probiotics support intestinal health
We assessed how a multi-strain probiotic, Serobioma, affects gut health in individuals with Irritable Bowel Syndrome (IBS). This study involved IBS patients and healthy controls, looking at how Serobioma interacts with mucosal mediators from IBS patients' biopsies.
Remarkably, Serobioma improved the integrity of intestinal cell layers affected by IBS mediators, particularly in patients with diarrhea and mixed bowel habits. It successfully countered increased permeability, indicating its potential to support gut barrier function in IBS.
Remarkably, Serobioma improved the integrity of intestinal cell layers affected by IBS mediators, particularly in patients with diarrhea and mixed bowel habits. It successfully countered increased permeability, indicating its potential to support gut barrier function in IBS.
9
Probiotics effective for IBS relief
We aimed to explore the effectiveness of probiotics in managing irritable bowel syndrome (IBS). By reviewing 52 rigorous trials with nearly 6,300 participants, we found that probiotics significantly enhanced overall symptom relief, improved subjective well-being, and alleviated abdominal pain.
Notably, a daily dose of 10 billion cfu seemed particularly beneficial, with effects visible as early as four weeks into treatment. While probiotics demonstrated clear advantages, the roles of prebiotics and synbiotics remain less certain due to limited studies.
Notably, a daily dose of 10 billion cfu seemed particularly beneficial, with effects visible as early as four weeks into treatment. While probiotics demonstrated clear advantages, the roles of prebiotics and synbiotics remain less certain due to limited studies.
8
We investigated whether delivering probiotics via colonoscopy could help patients suffering from irritable bowel syndrome with diarrhea (IBS-D). In a controlled trial involving 22 IBS-D patients, we found notable improvements in symptoms.
After treatment, participants experienced fewer bowel movements, reduced abdominal pain, and better quality of life scores. However, changes in gut microbiota diversity weren’t significantly different between the groups. This suggests probiotics might be beneficial but highlights the need for further research.
After treatment, participants experienced fewer bowel movements, reduced abdominal pain, and better quality of life scores. However, changes in gut microbiota diversity weren’t significantly different between the groups. This suggests probiotics might be beneficial but highlights the need for further research.
We studied the effects of a biotic mixture—microencapsulated sodium butyrate, specific probiotics, and short-chain fructooligosaccharides—on irritable bowel syndrome (IBS). This randomized, double-blind, placebo-controlled trial included 120 adults over 12 weeks. We found that after four weeks, more patients reported symptom relief with the biotic treatment compared to placebo (64.7% vs. 42.0%). By week 12, fewer patients in the biotic group experienced symptom worsening. While the intervention showed safety and some positive results, it did not significantly improve overall quality of life measures.
9
Synbiotic reduced IBS pain effectively
We explored the effects of a new synbiotic combination of chitin-glucan (CG) and NCFM in a rat model of irritable bowel syndrome (IBS).
After nine weeks, we found that both CG and NCFM reduced abdominal pain when used separately, but together, they significantly lessened visceral pain and intestinal inflammation.
Not only did this combination improve pain perception, but it also reduced colon lesions and inflammation markers. Overall, our findings suggest that this synbiotic approach holds promise for alleviating IBS symptoms.
After nine weeks, we found that both CG and NCFM reduced abdominal pain when used separately, but together, they significantly lessened visceral pain and intestinal inflammation.
Not only did this combination improve pain perception, but it also reduced colon lesions and inflammation markers. Overall, our findings suggest that this synbiotic approach holds promise for alleviating IBS symptoms.
References
- Barbaro MR, Bianco F, Cremon C, Marasco G, Stanghellini V, et al. A Probiotic Mixture of LR 32, BL 04, and BB 536 Counteracts the Increase in Permeability Induced by the Mucosal Mediators of Irritable Bowel Syndrome by Acting on Zonula Occludens 1. Int J Mol Sci. 2025;26. doi:10.3390/ijms26062656
- Wei JJ, Zhang PH, Yang ZY, Liu LP, Lian TT, et al. Colonoscopic administration of probiotics to treat irritable bowel syndrome with predominant diarrhea: a randomized placebo-controlled clinical trial. Surg Endosc. 2025;39:1893. doi:10.1007/s00464-025-11542-6
- Gąsiorowska A, Romanowski M, Walecka-Kapica E, Kaczka A, Chojnacki C, et al. Efficacy and Safety of a Mixture of Microencapsulated Sodium Butyrate, Probiotics, and Short Chain Fructooligosaccharides in Patients with Irritable Bowel Syndrome-A Randomized, Double-Blind, Placebo-Controlled Study. J Clin Med. 2024;14. doi:10.3390/jcm14010006
- Yu QX, Wang DD, Dong PJ, Zheng LH. Probiotics Combined With Trimebutine for the Treatment of Irritable Bowel Syndrome Patients: A Systematic Review and Meta-Analysis. J Gastroenterol Hepatol. 2025;40:677. doi:10.1111/jgh.16858
- Capirchio L, Rousseaux C, Dubuquoy C, Ouwehand AC, Maquet V, et al. A Synbiotic Combining Chitin-Glucan and NCFM Induces a Colonic Molecular Signature Soothing Intestinal Pain and Inflammation in an Animal Model of IBS. Int J Mol Sci. 2024;25. doi:10.3390/ijms251910732
- Biskou O, Walter S, Israelsen H, Winberg ME, Bednarska O, et al. ReFerm: a postbiotic fermented oat gruel composition is reducing mast cell degranulation in the colon of patients with irritable bowel syndrome. Front Med (Lausanne). 2024;11:1408623. doi:10.3389/fmed.2024.1408623
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- Torres-Maravilla E, Carvalho FA, Holowacz S, Delannoy J, Lenoir L, et al. Screening of probiotic strains to improve visceral hypersensitivity in irritable bowel syndrome by using in vitro and in vivo approaches. Benef Microbes. 2024;15:293. doi:10.1163/18762891-bja00006
- Sarkawi M, Raja Ali RA, Abdul Wahab N, Abdul Rathi ND, Mokhtar NM. A randomized, double-blinded, placebo-controlled clinical trial on Lactobacillus-containing cultured milk drink as adjuvant therapy for depression in irritable bowel syndrome. Sci Rep. 2024;14:9478. doi:10.1038/s41598-024-60029-2
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- Shanshal SA, Alsaaty MH, Al-Qazaz H, Al-Zidan RN. Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial. Ceska Slov Farm. 2024;72:233.
- Chang YH, Choi YJ, Shin CM, Moon JS, Kim TY, et al. Efficacy of Quadruple-coated Probiotics in Patients With Irritable Bowel Syndrome: A Randomized, Double-blind, Placebo-controlled, Parallel-group Study. J Neurogastroenterol Motil. 2024;30:73. doi:10.5056/jnm23036
- Drozdov VN, Shikh EV, Astapovskii AA, Khalaidzheva KN, Solovieva SA, et al. [Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea and antibiotic-associated diarrhea]. Vopr Pitan. 2023;92:92. doi:10.33029/0042-8833-2023-92-4-92-103
- Zhang WX, Shi LB, Zhou MS, Wu J, Shi HY. Efficacy of probiotics, prebiotics and synbiotics in irritable bowel syndrome: a systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials. J Med Microbiol. 2023;72. doi:10.1099/jmm.0.001758
- Goodoory VC, Khasawneh M, Black CJ, Quigley EMM, Moayyedi P, et al. Efficacy of Probiotics in Irritable Bowel Syndrome: Systematic Review and Meta-analysis. Gastroenterology. 2023;165:1206. doi:10.1053/j.gastro.2023.07.018
- Kwon H, Nam EH, Kim H, Jo H, Bang WY, et al. Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial. Sci Rep. 2024;14:22384. doi:10.1038/s41598-024-72887-x
- Zhang L, Ni X, Jiang M, Du M, Zhang S, et al. Strains for Alleviation of Irritable Bowel Disease and Chronic Fatigue Syndrome. Microorganisms. 2024;12. doi:10.3390/microorganisms12061081
- Skrzydło-Radomańska B, Prozorow-Król B, Cichoż-Lach H, Majsiak E, Bierła JB, et al. The Effectiveness of Synbiotic Preparation Containing and Probiotic Strains and Short Chain Fructooligosaccharides in Patients with Diarrhea Predominant Irritable Bowel Syndrome-A Randomized Double-Blind, Placebo-Controlled Study. Nutrients. 2020;12. doi:10.3390/nu12071999
- Bonfrate L, Di Palo DM, Celano G, Albert A, Vitellio P, et al. Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients. Eur J Clin Invest. 2020;50:e13201. doi:10.1111/eci.13201
- Ding FCL, Karkhaneh M, Zorzela L, Jou H, Vohra S. Probiotics for paediatric functional abdominal pain disorders: A rapid review. Paediatr Child Health. 2019;24:383. doi:10.1093/pch/pxz036
- Nocerino R, Di Costanzo M, Bedogni G, Cosenza L, Maddalena Y, et al. Dietary Treatment with Extensively Hydrolyzed Casein Formula Containing the Probiotic Lactobacillus rhamnosus GG Prevents the Occurrence of Functional Gastrointestinal Disorders in Children with Cow's Milk Allergy. J Pediatr. 2019;213:137. doi:10.1016/j.jpeds.2019.06.004
- Hojsak I. Probiotics in Functional Gastrointestinal Disorders. Adv Exp Med Biol. 2019;1125:121. doi:10.1007/5584_2018_321
- Han X, Lee A, Huang S, Gao J, Spence JR, et al. Lactobacillus rhamnosus GG prevents epithelial barrier dysfunction induced by interferon-gamma and fecal supernatants from irritable bowel syndrome patients in human intestinal enteroids and colonoids. Gut Microbes. 2019;10:59. doi:10.1080/19490976.2018.1479625
- Preston K, Krumian R, Hattner J, de Montigny D, Stewart M, et al. Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R and Lactobacillus rhamnosus CLR2 improve quality-of-life and IBS symptoms: a double-blind, randomised, placebo-controlled study. Benef Microbes. 2018;9:697. doi:10.3920/BM2017.0105
- Wegh CAM, Benninga MA, Tabbers MM. Effectiveness of Probiotics in Children With Functional Abdominal Pain Disorders and Functional Constipation: A Systematic Review. J Clin Gastroenterol. 2018;52 Suppl 1, Proceedings from the 9th Probiotics, Prebiotics and New Foods, Nutraceuticals and Botanicals for Nutrition & Human and Microbiota Health Meeting, held in Rome, Italy from September 10 to 12, 2017:S10. doi:10.1097/MCG.0000000000001054
- Darbaky Y, Evrard B, Patrier S, Falenta J, Garcin S, et al. Oral probiotic treatment of Lactobacillus rhamnosus Lcr35 prevents visceral hypersensitivity to a colonic inflammation and an acute psychological stress. J Appl Microbiol. 2017;122:188. doi:10.1111/jam.13320
- Yoon H, Park YS, Lee DH, Seo JG, Shin CM, et al. Effect of administering a multi-species probiotic mixture on the changes in fecal microbiota and symptoms of irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Clin Biochem Nutr. 2015;57:129. doi:10.3164/jcbn.15-14
- Cruchet S, Furnes R, Maruy A, Hebel E, Palacios J, et al. The use of probiotics in pediatric gastroenterology: a review of the literature and recommendations by Latin-American experts. Paediatr Drugs. 2015;17:199. doi:10.1007/s40272-015-0124-6
- Koc F, Arendt E, Coffey A, Ross RP, Stanton C. Impact of low FODMAP sourdough bread on gut microbiota using an colonic fermentation model. Front Microbiol. 2024;15:1496022. doi:10.3389/fmicb.2024.1496022
- Andreozzi V, Cuoco S, Balestrieri M, Fierro F, Ferrara N, et al. Synbiotic supplementation may globally improve non-motor symptoms in patients with stable Parkinson's disease: results from an open label single-arm study. Sci Rep. 2024;14:23095. doi:10.1038/s41598-024-74400-w
- Garvey SM, LeMoire A, Wang J, Lin L, Sharif B, et al. Safety and Tolerability of Microbial Inulinase Supplementation in Healthy Adults: A Randomized, Placebo-Controlled Trial. Gastro Hep Adv. 2024;3:920. doi:10.1016/j.gastha.2024.05.013
- Isakov VA, Pilipenko VI, Vlasova AV, Kochetkova AA. Evaluation of the Efficacy of Kombucha-Based Drink Enriched with Inulin and Vitamins for the Management of Constipation-Predominant Irritable Bowel Syndrome in Females: A Randomized Pilot Study. Curr Dev Nutr. 2023;7:102037. doi:10.1016/j.cdnut.2023.102037
- Pilipenko VI, Isakov VA, Morozov SV, Vlasova AV, Kochetkova AA. [Efficacy of newly developed kombucha-based specialized food product for treatment of constipation-predominant irritable bowel syndrome]. Vopr Pitan. 2022;91:95. doi:10.33029/0042-8833-2022-91-5-95-104
- Ochoa KC, Samant S, Liu A, Duysburgh C, Marzorati M, et al. In Vitro Efficacy of Targeted Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols Enzymatic Digestion in a High-Fidelity Simulated Gastrointestinal Environment. Gastro Hep Adv. 2023;2:283. doi:10.1016/j.gastha.2022.10.011
- Bărboi OB, Chirilă I, Ciortescu I, Anton C, Drug VL. Inulin, Choline and Silymarin in the Treatment of Irritable Bowel Syndrome with Constipation-Randomized Case-Control Study. J Clin Med. 2022;11. doi:10.3390/jcm11082248
- Gunn D, Abbas Z, Harris HC, Major G, Hoad C, et al. Psyllium reduces inulin-induced colonic gas production in IBS: MRI and fermentation studies. Gut. 2022;71:919. doi:10.1136/gutjnl-2021-324784
- Bărboi OB, Ciortescu I, Chirilă I, Anton C, Drug V. Effect of inulin in the treatment of irritable bowel syndrome with constipation (Review). Exp Ther Med. 2020;20:185. doi:10.3892/etm.2020.9315
- Ahluwalia B, Magnusson MK, Böhn L, Störsrud S, Larsson F, et al. Randomized clinical trial: Effects of Aloe barbadensis Mill. extract on symptoms, fecal microbiota and fecal metabolite profiles in patients with irritable bowel syndrome. Neurogastroenterol Motil. 2020;32:e13860. doi:10.1111/nmo.13860
- Abhari K, Saadati S, Hosseini-Oskouiee F, Yari Z, Hosseini H, et al. Is Bacillus coagulans supplementation plus low FODMAP diet superior to low FODMAP diet in irritable bowel syndrome management?. Eur J Nutr. 2020;59:2111. doi:10.1007/s00394-019-02060-y
- Baştürk A, Artan R, Yılmaz A. Efficacy of synbiotic, probiotic, and prebiotic treatments for irritable bowel syndrome in children: A randomized controlled trial. Turk J Gastroenterol. 2016;27:439. doi:10.5152/tjg.2016.16301
- Major G, Pritchard S, Murray K, Alappadan JP, Hoad CL, et al. Colon Hypersensitivity to Distension, Rather Than Excessive Gas Production, Produces Carbohydrate-Related Symptoms in Individuals With Irritable Bowel Syndrome. Gastroenterology. 2017;152:124. doi:10.1053/j.gastro.2016.09.062
- Pilipenko VI, Teplyuk DA, Shakhovskaya AK, Isakov VA, Vorobyova VM, et al. [Using a multicomponent functional food in IBS patients with constipation a comparative controlled study]. Vopr Pitan. 2016;85:84.
- Bogovič Matijašić B, Obermajer T, Lipoglavšek L, Sernel T, Locatelli I, et al. Effects of synbiotic fermented milk containing Lactobacillus acidophilus La-5 and Bifidobacterium animalis ssp. lactis BB-12 on the fecal microbiota of adults with irritable bowel syndrome: A randomized double-blind, placebo-controlled trial. J Dairy Sci. 2016;99:5008. doi:10.3168/jds.2015-10743
- Pilipenko VI, Teplyuk DA, Shakhovskaya AK, Isakov VA, Vorobyova VM, et al. [Dry jelly concentrate with vitamins and dietary fiber in patients with IBS with constipation: a comparative controlled study]. Vopr Pitan. 2015;84:83.
